DK166546C - Fremgangsmaade til spaltning af peptider og proteiner ved methionyl-bindingen - Google Patents
Fremgangsmaade til spaltning af peptider og proteiner ved methionyl-bindingenInfo
- Publication number
- DK166546C DK166546C DK516485A DK516485A DK166546C DK 166546 C DK166546 C DK 166546C DK 516485 A DK516485 A DK 516485A DK 516485 A DK516485 A DK 516485A DK 166546 C DK166546 C DK 166546C
- Authority
- DK
- Denmark
- Prior art keywords
- proteins
- methionyl
- bonding
- detecting peptides
- peptides
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 2
- 102000004169 proteins and genes Human genes 0.000 title abstract 2
- 108090000623 proteins and genes Proteins 0.000 title abstract 2
- 238000003776 cleavage reaction Methods 0.000 abstract 1
- QPJDMGCKMHUXFD-UHFFFAOYSA-N cyanogen chloride Chemical compound ClC#N QPJDMGCKMHUXFD-UHFFFAOYSA-N 0.000 abstract 1
- 230000007017 scission Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/12—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by hydrolysis, i.e. solvolysis in general
- C07K1/126—Aminolysis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/12—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by hydrolysis, i.e. solvolysis in general
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/81—Carrier - bound or immobilized peptides or proteins and the preparation thereof, e.g. biological cell or cell fragment as carrier
- Y10S530/812—Peptides or proteins is immobilized on, or in, an organic carrier
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Life Sciences & Earth Sciences (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
- Saccharide Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE3440988 | 1984-11-09 | ||
DE19843440988 DE3440988A1 (de) | 1984-11-09 | 1984-11-09 | Verfahren zur spaltung von peptiden und proteinen an der methionyl-bindung |
Publications (4)
Publication Number | Publication Date |
---|---|
DK516485D0 DK516485D0 (da) | 1985-11-08 |
DK516485A DK516485A (da) | 1986-05-10 |
DK166546B DK166546B (da) | 1993-06-07 |
DK166546C true DK166546C (da) | 1993-10-25 |
Family
ID=6249917
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK516485A DK166546C (da) | 1984-11-09 | 1985-11-08 | Fremgangsmaade til spaltning af peptider og proteiner ved methionyl-bindingen |
Country Status (15)
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4745178A (en) * | 1987-04-22 | 1988-05-17 | Eli Lilly And Company | Process for selective peptide bond cleavage using sulfoxides and CF3 CO |
DE3726655A1 (de) * | 1987-08-11 | 1989-02-23 | Hoechst Ag | Verfahren zur isolierung basischer proteine aus proteingemischen, welche solche basischen proteine enthalten |
US4945157A (en) * | 1988-05-27 | 1990-07-31 | University Of Florida | Novel Extraction procedure for protein G |
SK279686B6 (sk) * | 1990-09-05 | 1999-02-11 | Hoechst Aktiengesellschaft | Spôsob hydrolýzy reťazca aminokyselín preproinzulí |
EP0821006B1 (de) | 1996-07-26 | 2004-04-21 | Aventis Pharma Deutschland GmbH | Insulinderivate mit erhöhter Zinkbindung |
DE19726167B4 (de) | 1997-06-20 | 2008-01-24 | Sanofi-Aventis Deutschland Gmbh | Insulin, Verfahren zu seiner Herstellung und es enthaltende pharmazeutische Zubereitung |
DE19825447A1 (de) | 1998-06-06 | 1999-12-09 | Hoechst Marion Roussel De Gmbh | Neue Insulinanaloga mit erhöhter Zinkbildung |
DE10114178A1 (de) | 2001-03-23 | 2002-10-10 | Aventis Pharma Gmbh | Zinkfreie und zinkarme Insulinzubereitungen mit verbesserter Stabilität |
DE10227232A1 (de) | 2002-06-18 | 2004-01-15 | Aventis Pharma Deutschland Gmbh | Saure Insulinzubereitungen mit verbesserter Stabilität |
US7193035B2 (en) * | 2002-10-29 | 2007-03-20 | Sanofi-Aventis Deutschland Gmbh | Crystals of insulin analogs and processes for their preparation |
CN102159588B (zh) | 2008-08-07 | 2015-09-02 | 拜康有限公司 | 一种用于制备胰岛素化合物的方法 |
NZ592283A (en) | 2008-10-17 | 2012-09-28 | Sanofi Aventis Deutschland | Combination of an insulin and the GLP-1 agonist AVE0010 |
CN107308442B (zh) | 2009-11-13 | 2022-10-18 | 赛诺菲-安万特德国有限公司 | 包含glp-1激动剂、胰岛素和甲硫氨酸的药物组合物 |
DK2498801T3 (en) | 2009-11-13 | 2018-05-07 | Sanofi Aventis Deutschland | PHARMACEUTICAL COMPOSITION INCLUDING desPro36Exendin-4 (1-39) -Lys6-NH2 AND METHIONIN |
BR112013004756B1 (pt) | 2010-08-30 | 2020-04-28 | Sanofi Aventis Deutschland | uso de ave0010 para a fabricação de um medicamento para o tratamento da diabetes melito tipo 2 |
US9821032B2 (en) | 2011-05-13 | 2017-11-21 | Sanofi-Aventis Deutschland Gmbh | Pharmaceutical combination for improving glycemic control as add-on therapy to basal insulin |
JP6367115B2 (ja) | 2011-08-29 | 2018-08-01 | サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング | 2型糖尿病患者の血糖コントロールに使用する組合せ医薬 |
TWI559929B (en) | 2011-09-01 | 2016-12-01 | Sanofi Aventis Deutschland | Pharmaceutical composition for use in the treatment of a neurodegenerative disease |
US9950039B2 (en) | 2014-12-12 | 2018-04-24 | Sanofi-Aventis Deutschland Gmbh | Insulin glargine/lixisenatide fixed ratio formulation |
TWI748945B (zh) | 2015-03-13 | 2021-12-11 | 德商賽諾菲阿凡提斯德意志有限公司 | 第2型糖尿病病患治療 |
TW201705975A (zh) | 2015-03-18 | 2017-02-16 | 賽諾菲阿凡提斯德意志有限公司 | 第2型糖尿病病患之治療 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE337223B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * | 1967-05-23 | 1971-08-02 | Pharmacia Ab | |
US3935072A (en) * | 1972-08-10 | 1976-01-27 | Tanabe Seiyaku Co., Ltd. | Purification of coenzyme A |
US3876501A (en) * | 1973-05-17 | 1975-04-08 | Baxter Laboratories Inc | Binding enzymes to activated water-soluble carbohydrates |
US3919049A (en) * | 1974-06-27 | 1975-11-11 | Tokyo Tanabe Co | Process for preparing {62 -galactosidase |
SE8302758L (sv) * | 1983-05-17 | 1984-11-18 | Pharmacia Ab | Sett for uppspjelkning av disulfidbindningar och derigenom erhallen forening |
GB8317697D0 (en) * | 1983-06-29 | 1983-08-03 | Shell Int Research | Dissolution of peptides in non-aqueous and mixed non-aqueous/aqueous solvents |
US4496689A (en) * | 1983-12-27 | 1985-01-29 | Miles Laboratories, Inc. | Covalently attached complex of alpha-1-proteinase inhibitor with a water soluble polymer |
-
1984
- 1984-11-09 DE DE19843440988 patent/DE3440988A1/de not_active Withdrawn
-
1985
- 1985-10-31 DE DE8585113857T patent/DE3585078D1/de not_active Expired - Fee Related
- 1985-10-31 EP EP85113857A patent/EP0180920B1/de not_active Expired - Lifetime
- 1985-10-31 AT AT85113857T patent/ATE71109T1/de not_active IP Right Cessation
- 1985-11-07 GR GR852693A patent/GR852693B/el unknown
- 1985-11-07 US US06/795,920 patent/US4644057A/en not_active Expired - Lifetime
- 1985-11-07 PT PT81445A patent/PT81445B/pt not_active IP Right Cessation
- 1985-11-07 ES ES548617A patent/ES8701780A1/es not_active Expired
- 1985-11-07 FI FI854383A patent/FI85494C/fi not_active IP Right Cessation
- 1985-11-08 JP JP60249148A patent/JPH0714960B2/ja not_active Expired - Lifetime
- 1985-11-08 DK DK516485A patent/DK166546C/da not_active IP Right Cessation
- 1985-11-08 AU AU49713/85A patent/AU580348B2/en not_active Ceased
- 1985-11-08 ZA ZA858603A patent/ZA858603B/xx unknown
- 1985-11-08 CA CA000494971A patent/CA1247081A/en not_active Expired
- 1985-11-08 IE IE279585A patent/IE58683B1/en not_active IP Right Cessation
- 1985-11-09 KR KR1019850008387A patent/KR930007428B1/ko not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
FI85494B (fi) | 1992-01-15 |
JPH0714960B2 (ja) | 1995-02-22 |
KR860003832A (ko) | 1986-06-13 |
DE3585078D1 (de) | 1992-02-13 |
US4644057A (en) | 1987-02-17 |
FI854383L (fi) | 1986-05-10 |
FI85494C (fi) | 1992-04-27 |
ES8701780A1 (es) | 1986-12-01 |
JPS61115096A (ja) | 1986-06-02 |
DK516485D0 (da) | 1985-11-08 |
CA1247081A (en) | 1988-12-20 |
PT81445B (pt) | 1987-12-30 |
IE58683B1 (en) | 1993-11-03 |
PT81445A (de) | 1985-12-01 |
IE852795L (en) | 1986-05-09 |
FI854383A0 (fi) | 1985-11-07 |
DK166546B (da) | 1993-06-07 |
EP0180920B1 (de) | 1992-01-02 |
ZA858603B (en) | 1986-07-30 |
EP0180920A3 (en) | 1989-01-04 |
ATE71109T1 (de) | 1992-01-15 |
EP0180920A2 (de) | 1986-05-14 |
AU4971385A (en) | 1986-05-15 |
GR852693B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1986-03-10 |
AU580348B2 (en) | 1989-01-12 |
KR930007428B1 (ko) | 1993-08-10 |
ES548617A0 (es) | 1986-12-01 |
DE3440988A1 (de) | 1986-07-10 |
DK516485A (da) | 1986-05-10 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DK166546C (da) | Fremgangsmaade til spaltning af peptider og proteiner ved methionyl-bindingen | |
DK84288A (da) | Fusionsproteiner og oprensning deraf | |
DK0458841T3 (da) | Fremgangsmåde til anvendelse og fremstilling af peptider | |
DK496489D0 (da) | Fremgangsmaade til stabilisering af proteiner ved tilrettelaeggelse af indbyrdes elektrostatiske paavirkninger ved metalionbindingssteder | |
FI870981A7 (fi) | Menetelmä yhdistelmä-DNA-tekniikalla mikrobin avulla tuotetun risiinitoksiinin A-ketjun talteenottamiseksi. | |
DK315187A (da) | Fremgangsmaade til forbedret fremstilling af antistoffer under anvendelse af uoploeseliggjorte immunkomplekser | |
DE69018625D1 (de) | Verfahren zum aufkonzentrieren von chlorgas. | |
FI882396L (fi) | Menetelmä keraamisten kappaleiden sitomiseksi toisiinsa | |
FI822065A7 (fi) | Menetelmä aspartiinihapon ja glutamiinihapon täydelliseksi tai osittaiseksi poistamiseksi proteiiniproteiinihydrolyysisaasteista ja aminohapposeoksista sekä näin saadut aminohapposeokset. | |
ATE50458T1 (de) | Bestimmung von fibrin mit fibrin-spezifischen antikoerpern. | |
DE3576527D1 (de) | Trennung von aminosaeureracematen. | |
DK0428984T3 (da) | Fremgangsmåde til fraskillelse af aminosyrer | |
DE3767052D1 (de) | Verfahren zur trennung von monohydraten von l-cysteine-hydrochloriden. | |
ATE78873T1 (de) | Verfahren zur selektiven spaltung von fusionsproteinen. | |
DK0401657T3 (da) | Fremgangsmåde til C-terminal modificering af proteiner | |
FI884652L (fi) | Menetelmä t-PA-kaltaisten proteiinien tuotannon tehostamiseksi | |
GB2256870B (en) | Method for enhancing recovery of recombinant proteins | |
DK370186A (da) | Kloningsvehikel til kloning af et stort dna-fragment og en vaccine indeholdende 987p fimbrielt protein | |
DK162604C (da) | Fremgangsmaade til fremstilling af humant immuninterferon samt farmaceutiske praeparater indeholdende immuninterferon fremstillet ved fremgangsmaaden ifoelge opfindelsen og anvendelse af humant interferon fremstillet ved fremgangsmaaden ifoelge opfindelsen til fremstilling af et terapeutisk middel | |
DK571189A (da) | Monoklonalt antistof, der genkender et reg-protein, hybridoma frembringende et saadant og metode til afsloering af reg-protein | |
DK212284D0 (da) | Fremgangsmaade til fremstilling af 20-keto-delta 16-steroider og mellemprodukter dannet ved denne fremgangsmaade | |
FI860043A7 (fi) | Peptidisubstraatit sekä menetelmä endotoksiinin kvantitatiiviseksi määrittämiseksi. | |
DK277688D0 (da) | Fremgangsmaade til fremstilling af et hmg-coa-lignende protein | |
ATE33019T1 (de) | Verfahren zum oeffnen des ringes von gemdicyanepoxyden und mit diesem verfahren hergestellte verbindungen. | |
FI864044A7 (fi) | Menetelmä vasta-aineiden tai antigeenien määrittämiseksi. |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PBP | Patent lapsed |
Country of ref document: DK |