PT71917B - Process for preparing novel antiinflamatory and immunoregulatory piridines and pyrimidines - Google Patents
Process for preparing novel antiinflamatory and immunoregulatory piridines and pyrimidinesInfo
- Publication number
- PT71917B PT71917B PT71917A PT7191780A PT71917B PT 71917 B PT71917 B PT 71917B PT 71917 A PT71917 A PT 71917A PT 7191780 A PT7191780 A PT 7191780A PT 71917 B PT71917 B PT 71917B
- Authority
- PT
- Portugal
- Prior art keywords
- pyridine
- immunoregulatory
- piridines
- antiinflamatory
- pyrimidines
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
- C07D213/32—Sulfur atoms
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01D—HARVESTING; MOWING
- A01D34/00—Mowers; Mowing apparatus of harvesters
- A01D34/001—Accessories not otherwise provided for
- A01D34/003—Means for cleaning the machine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C33/00—Moulds or cores; Details thereof or accessories therefor
- B29C33/56—Coatings, e.g. enameled or galvanised; Releasing, lubricating or separating agents
- B29C33/60—Releasing, lubricating or separating agents
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C70/00—Shaping composites, i.e. plastics material comprising reinforcements, fillers or preformed parts, e.g. inserts
- B29C70/68—Shaping composites, i.e. plastics material comprising reinforcements, fillers or preformed parts, e.g. inserts by incorporating or moulding on preformed parts, e.g. inserts or layers, e.g. foam blocks
- B29C70/84—Shaping composites, i.e. plastics material comprising reinforcements, fillers or preformed parts, e.g. inserts by incorporating or moulding on preformed parts, e.g. inserts or layers, e.g. foam blocks by moulding material on preformed parts to be joined
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/55—Acids; Esters
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/63—One oxygen atom
- C07D213/65—One oxygen atom attached in position 3 or 5
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/26—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
- F16C—SHAFTS; FLEXIBLE SHAFTS; ELEMENTS OR CRANKSHAFT MECHANISMS; ROTARY BODIES OTHER THAN GEARING ELEMENTS; BEARINGS
- F16C11/00—Pivots; Pivotal connections
- F16C11/04—Pivotal connections
- F16C11/06—Ball-joints; Other joints having more than one degree of angular freedom, i.e. universal joints
- F16C11/0604—Construction of the male part
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
- F16C—SHAFTS; FLEXIBLE SHAFTS; ELEMENTS OR CRANKSHAFT MECHANISMS; ROTARY BODIES OTHER THAN GEARING ELEMENTS; BEARINGS
- F16C11/00—Pivots; Pivotal connections
- F16C11/04—Pivotal connections
- F16C11/06—Ball-joints; Other joints having more than one degree of angular freedom, i.e. universal joints
- F16C11/068—Special features relating to lubrication
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Mechanical Engineering (AREA)
- General Engineering & Computer Science (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Environmental Sciences (AREA)
- Composite Materials (AREA)
- Transplantation (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/085,011 US4246263A (en) | 1979-10-15 | 1979-10-15 | Antiinflammatory and immunoregulatory pyrimidines, their method of use and pharmaceutical compositions |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PT71917A PT71917A (en) | 1980-12-01 |
| PT71917B true PT71917B (en) | 1983-01-10 |
Family
ID=22188737
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT71917A PT71917B (en) | 1979-10-15 | 1980-10-14 | Process for preparing novel antiinflamatory and immunoregulatory piridines and pyrimidines |
Country Status (39)
| Country | Link |
|---|---|
| US (1) | US4246263A (pt) |
| JP (1) | JPS5663962A (pt) |
| KR (2) | KR840001614B1 (pt) |
| AR (3) | AR226864A1 (pt) |
| AT (2) | AT377513B (pt) |
| AU (1) | AU517763B2 (pt) |
| BE (1) | BE885709A (pt) |
| CA (1) | CA1156231A (pt) |
| CH (1) | CH646425A5 (pt) |
| CS (2) | CS226020B2 (pt) |
| DD (2) | DD154816B3 (pt) |
| DE (1) | DE3038593A1 (pt) |
| DK (1) | DK152427C (pt) |
| EG (1) | EG14676A (pt) |
| ES (2) | ES8201972A1 (pt) |
| FI (1) | FI75560C (pt) |
| FR (1) | FR2467199A1 (pt) |
| GB (2) | GB2092133B (pt) |
| GR (1) | GR70311B (pt) |
| HK (2) | HK1185A (pt) |
| HU (2) | HU183233B (pt) |
| IE (1) | IE50665B1 (pt) |
| IL (1) | IL61261A (pt) |
| IN (2) | IN154554B (pt) |
| IT (1) | IT1195269B (pt) |
| KE (2) | KE3461A (pt) |
| LU (1) | LU82844A1 (pt) |
| MY (2) | MY8500325A (pt) |
| NL (1) | NL8005652A (pt) |
| NO (1) | NO156566C (pt) |
| NZ (1) | NZ195246A (pt) |
| PH (1) | PH18277A (pt) |
| PL (2) | PL125314B1 (pt) |
| PT (1) | PT71917B (pt) |
| SE (1) | SE437023B (pt) |
| SG (2) | SG56384G (pt) |
| SU (2) | SU1083907A3 (pt) |
| YU (2) | YU41740B (pt) |
| ZA (1) | ZA806306B (pt) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4371696A (en) * | 1980-07-14 | 1983-02-01 | Pfizer Inc. | Certain pyridine methylthio acetaldehyde derivatives and non-cyclic and cyclic acetals thereof |
| GB8405896D0 (en) * | 1984-03-07 | 1984-04-11 | Sandoz Ltd | Organic compounds |
| EP0311616B1 (en) * | 1986-06-17 | 1991-09-25 | Biogen, Inc. | Combinations of gamma interferons and anti-inflammatory or anti-pyretic agents for treating diseases |
| WO2003024955A2 (en) * | 2001-09-18 | 2003-03-27 | Sunesis Pharmaceuticals, Inc. | Small molecule inhibitors of caspases |
| US8143453B2 (en) * | 2005-02-25 | 2012-03-27 | Temple University—Of the Commonwealth System of Higher Education | Unsaturated sulfides, sulfones, sulfoxides and sulfonamides synthesis |
| JP5287033B2 (ja) * | 2007-08-23 | 2013-09-11 | 住友化学株式会社 | 含フッ素有機硫黄化合物およびその有害節足動物防除剤 |
| CN108530606B (zh) * | 2018-04-19 | 2020-11-20 | 山东师范大学 | 一种pH敏感性医用聚氨酯脲材料及其制备方法 |
| US11981625B2 (en) | 2018-10-08 | 2024-05-14 | Ecolab Usa Inc. | Sulfide-based compounds and uses thereof |
| CN110483740B (zh) * | 2019-08-12 | 2021-08-27 | 山东师范大学 | 一种聚合物、pH敏感性纳米囊泡及制备方法与应用 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3409626A (en) * | 1963-09-17 | 1968-11-05 | Neisler Lab Inc | Indolylethyl pyridinium quaternary ammonium compounds |
| NL144484B (nl) * | 1967-07-26 | 1975-01-15 | Merck & Co Inc | Werkwijze ter bereiding van een geneesmiddel met anti-anflammatoire werking, alsmede werkwijze ter bereiding van de anti-inflammatoir werkzame aralkylmercaptoaminozuren. |
| US3558640A (en) * | 1967-12-20 | 1971-01-26 | Merck & Co Inc | Certain pyridyl and thiazolyl methylthiopropionic acids and derivatives |
| US3636074A (en) * | 1968-08-05 | 1972-01-18 | Hooker Chemical Corp | Novel mercaptophenol derivatives |
| US3591584A (en) | 1968-08-27 | 1971-07-06 | Pfizer | Benzothiazine dioxides |
| US3818009A (en) * | 1969-12-29 | 1974-06-18 | Lilly Co Eli | Alpha, alpha-disubstituted-5-pyrimidinemethanes |
| US3676463A (en) | 1970-10-15 | 1972-07-11 | Pfizer | Oxobenzofuran carboxamides |
| US3707475A (en) | 1970-11-16 | 1972-12-26 | Pfizer | Antiinflammatory imidazoles |
| JPS52125170A (en) * | 1976-04-12 | 1977-10-20 | Yoshitomi Pharmaceut Ind Ltd | Pyridine derivatives |
-
1979
- 1979-10-15 US US06/085,011 patent/US4246263A/en not_active Expired - Lifetime
-
1980
- 1980-08-16 IN IN597/DEL/80A patent/IN154554B/en unknown
- 1980-09-24 DK DK403080A patent/DK152427C/da not_active IP Right Cessation
- 1980-10-09 AR AR282823A patent/AR226864A1/es active
- 1980-10-10 CA CA000362238A patent/CA1156231A/en not_active Expired
- 1980-10-11 GR GR63147A patent/GR70311B/el unknown
- 1980-10-13 IL IL61261A patent/IL61261A/xx unknown
- 1980-10-13 AT AT0508980A patent/AT377513B/de not_active IP Right Cessation
- 1980-10-13 YU YU2626/80A patent/YU41740B/xx unknown
- 1980-10-13 DE DE19803038593 patent/DE3038593A1/de active Granted
- 1980-10-13 GB GB8137997A patent/GB2092133B/en not_active Expired
- 1980-10-13 GB GB8032971A patent/GB2061928B/en not_active Expired
- 1980-10-13 NZ NZ195246A patent/NZ195246A/en unknown
- 1980-10-13 LU LU82844A patent/LU82844A1/fr unknown
- 1980-10-14 PT PT71917A patent/PT71917B/pt unknown
- 1980-10-14 ZA ZA00806306A patent/ZA806306B/xx unknown
- 1980-10-14 PH PH24725A patent/PH18277A/en unknown
- 1980-10-14 HU HU802494A patent/HU183233B/hu not_active IP Right Cessation
- 1980-10-14 ES ES495932A patent/ES8201972A1/es not_active Expired
- 1980-10-14 DD DD80224544A patent/DD154816B3/de not_active IP Right Cessation
- 1980-10-14 EG EG80638A patent/EG14676A/xx active
- 1980-10-14 FR FR8021931A patent/FR2467199A1/fr active Granted
- 1980-10-14 JP JP14357280A patent/JPS5663962A/ja active Granted
- 1980-10-14 AU AU63240/80A patent/AU517763B2/en not_active Ceased
- 1980-10-14 FI FI803239A patent/FI75560C/fi not_active IP Right Cessation
- 1980-10-14 NO NO803073A patent/NO156566C/no unknown
- 1980-10-14 SE SE8007193A patent/SE437023B/sv not_active IP Right Cessation
- 1980-10-14 SU SU802993951A patent/SU1083907A3/ru active
- 1980-10-14 IT IT25324/80A patent/IT1195269B/it active
- 1980-10-14 IE IE2125/80A patent/IE50665B1/en unknown
- 1980-10-14 BE BE0/202467A patent/BE885709A/fr not_active IP Right Cessation
- 1980-10-14 HU HU83101A patent/HU191824B/hu not_active IP Right Cessation
- 1980-10-14 NL NL8005652A patent/NL8005652A/nl not_active Application Discontinuation
- 1980-10-15 KR KR1019800003966A patent/KR840001614B1/ko active
- 1980-10-15 PL PL1980227307A patent/PL125314B1/pl unknown
- 1980-10-15 CS CS806985A patent/CS226020B2/cs unknown
- 1980-10-15 PL PL1980231782A patent/PL125402B1/pl unknown
- 1980-10-15 CH CH771980A patent/CH646425A5/fr not_active IP Right Cessation
-
1981
- 1981-09-08 CS CS816610A patent/CS226034B2/cs unknown
- 1981-09-16 ES ES505544A patent/ES505544A0/es active Granted
- 1981-11-04 SU SU813349450A patent/SU1144617A3/ru active
-
1982
- 1982-01-18 DD DD82236826A patent/DD202543A5/de not_active IP Right Cessation
- 1982-02-18 AR AR288464A patent/AR227576A1/es active
- 1982-02-18 AR AR288463A patent/AR227089A1/es active
- 1982-12-01 YU YU2668/82A patent/YU42059B/xx unknown
-
1983
- 1983-07-22 AT AT0268783A patent/AT379801B/de not_active IP Right Cessation
-
1984
- 1984-06-05 IN IN464/DEL/84A patent/IN163553B/en unknown
- 1984-08-13 SG SG563/84A patent/SG56384G/en unknown
- 1984-08-22 KR KR1019840005076A patent/KR840001615B1/ko not_active IP Right Cessation
- 1984-09-24 KE KE3461A patent/KE3461A/xx unknown
- 1984-09-25 SG SG691/84A patent/SG69184G/en unknown
- 1984-10-05 KE KE3466A patent/KE3466A/xx unknown
-
1985
- 1985-01-03 HK HK11/85A patent/HK1185A/xx unknown
- 1985-12-30 MY MY325/85A patent/MY8500325A/xx unknown
- 1985-12-30 MY MY323/85A patent/MY8500323A/xx unknown
-
1987
- 1987-09-17 HK HK668/87A patent/HK66887A/xx unknown
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