US5625A
(en)
|
|
1848-06-13 |
|
Machinery for cutting and punching copper sheathing |
US126A
(en)
|
|
1837-02-16 |
|
Improvement in machines for cutting the screws of screw-bedsteads |
FR2413974A1
(fr)
|
1978-01-06 |
1979-08-03 |
David Bernard |
Sechoir pour feuilles imprimees par serigraphie
|
US4444887A
(en)
|
1979-12-10 |
1984-04-24 |
Sloan-Kettering Institute |
Process for making human antibody producing B-lymphocytes
|
US5179017A
(en)
|
1980-02-25 |
1993-01-12 |
The Trustees Of Columbia University In The City Of New York |
Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials
|
US4399216A
(en)
|
1980-02-25 |
1983-08-16 |
The Trustees Of Columbia University |
Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials
|
US4634665A
(en)
|
1980-02-25 |
1987-01-06 |
The Trustees Of Columbia University In The City Of New York |
Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials
|
US4309418A
(en)
|
1980-03-25 |
1982-01-05 |
Sloan-Kettering Research Institute For Cancer |
Anti-tumor agent from human serum and process
|
US4475196A
(en)
|
1981-03-06 |
1984-10-02 |
Zor Clair G |
Instrument for locating faults in aircraft passenger reading light and attendant call control system
|
US4447233A
(en)
|
1981-04-10 |
1984-05-08 |
Parker-Hannifin Corporation |
Medication infusion pump
|
SE8204382L
(sv)
|
1981-07-21 |
1983-01-22 |
Hayashibara Biochem Lab |
Sett att framstella malcellysfaktor och anvendning derav
|
US4439196A
(en)
|
1982-03-18 |
1984-03-27 |
Merck & Co., Inc. |
Osmotic drug delivery system
|
US4522811A
(en)
|
1982-07-08 |
1985-06-11 |
Syntex (U.S.A.) Inc. |
Serial injection of muramyldipeptides and liposomes enhances the anti-infective activity of muramyldipeptides
|
US4716111A
(en)
|
1982-08-11 |
1987-12-29 |
Trustees Of Boston University |
Process for producing human antibodies
|
US4457916A
(en)
|
1982-08-31 |
1984-07-03 |
Asahi Kasei Kogyo Kabushiki Kaisha |
Method for stabilizing Tumor Necrosis Factor and a stable aqueous solution or powder containing the same
|
US4447224A
(en)
|
1982-09-20 |
1984-05-08 |
Infusaid Corporation |
Variable flow implantable infusion apparatus
|
US4510245A
(en)
|
1982-11-18 |
1985-04-09 |
Chiron Corporation |
Adenovirus promoter system
|
US4487603A
(en)
|
1982-11-26 |
1984-12-11 |
Cordis Corporation |
Implantable microinfusion pump system
|
CA1254846A
(en)
|
1982-11-30 |
1989-05-30 |
Anthony Albino |
Monoclonal antibodies against melanocytes and melanomas
|
GB8308235D0
(en)
|
1983-03-25 |
1983-05-05 |
Celltech Ltd |
Polypeptides
|
US4816567A
(en)
|
1983-04-08 |
1989-03-28 |
Genentech, Inc. |
Recombinant immunoglobin preparations
|
US4486194A
(en)
|
1983-06-08 |
1984-12-04 |
James Ferrara |
Therapeutic device for administering medicaments through the skin
|
US5288852A
(en)
|
1984-03-06 |
1994-02-22 |
Dainippon Pharmaceutical Co., Ltd. |
Human tumor necrosis factor polypeptides
|
US4879226A
(en)
|
1984-04-06 |
1989-11-07 |
Asahi Kasei Kogyo Kabushiki Kaisha |
Novel human physiologically active polypeptide
|
DE3423234A1
(de)
|
1984-06-23 |
1986-02-06 |
Boehringer Ingelheim International GmbH, 6507 Ingelheim |
Synergistische mischungen von interferonen und tumor-nekrose-faktor
|
US5807715A
(en)
|
1984-08-27 |
1998-09-15 |
The Board Of Trustees Of The Leland Stanford Junior University |
Methods and transformed mammalian lymphocyte cells for producing functional antigen-binding protein including chimeric immunoglobulin
|
US4677063A
(en)
|
1985-05-02 |
1987-06-30 |
Cetus Corporation |
Human tumor necrosis factor
|
US4677064A
(en)
|
1984-11-09 |
1987-06-30 |
Cetus Corporation |
Human tumor necrosis factor
|
ATE73856T1
(de)
|
1984-12-21 |
1992-04-15 |
Biogen Inc |
Reinigung, herstellung und verwendung von tumor- nekrosisfaktoren.
|
US5168062A
(en)
|
1985-01-30 |
1992-12-01 |
University Of Iowa Research Foundation |
Transfer vectors and microorganisms containing human cytomegalovirus immediate-early promoter-regulatory DNA sequence
|
US4661446A
(en)
|
1985-02-19 |
1987-04-28 |
Dana-Farber Cancer Institute, Inc. |
Monoclonal antibodies and method of immunizing therewith
|
US4596556A
(en)
|
1985-03-25 |
1986-06-24 |
Bioject, Inc. |
Hypodermic injection apparatus
|
US4681760A
(en)
|
1985-04-17 |
1987-07-21 |
The Board Of Trustees Of The Leland Stanford Junior University |
Method of conferring immunotolerance to a specific antigen
|
US4661445A
(en)
|
1985-05-24 |
1987-04-28 |
Saxinger W Carl |
Competitive ELISA for the detection of HTLV-III antibodies
|
US5374548A
(en)
|
1986-05-02 |
1994-12-20 |
Genentech, Inc. |
Methods and compositions for the attachment of proteins to liposomes using a glycophospholipid anchor
|
MX9203291A
(es)
|
1985-06-26 |
1992-08-01 |
Liposome Co Inc |
Metodo para acoplamiento de liposomas.
|
US4676980A
(en)
|
1985-09-23 |
1987-06-30 |
The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services |
Target specific cross-linked heteroantibodies
|
US5059530A
(en)
|
1985-09-30 |
1991-10-22 |
Suntory Ltd. |
Expression vector for human TNF
|
US4968615A
(en)
|
1985-12-18 |
1990-11-06 |
Ciba-Geigy Corporation |
Deoxyribonucleic acid segment from a virus
|
US5225539A
(en)
|
1986-03-27 |
1993-07-06 |
Medical Research Council |
Recombinant altered antibodies and methods of making altered antibodies
|
GB8607679D0
(en)
|
1986-03-27 |
1986-04-30 |
Winter G P |
Recombinant dna product
|
US5002876A
(en)
|
1986-09-22 |
1991-03-26 |
Phillips Petroleum Company |
Yeast production of human tumor necrosis factor
|
US4985241A
(en)
|
1986-11-21 |
1991-01-15 |
Cetus Corporation |
Therapeutic combination of free-radical scavenger and tumor necrosis factor
|
US4963354A
(en)
|
1987-01-21 |
1990-10-16 |
Genentech, Inc. |
Use of tumor necrosis factor (TNF) as an adjuvant
|
DE3852304T3
(de)
|
1987-03-02 |
1999-07-01 |
Enzon Lab Inc |
Organismus als Träger für "Single Chain Antibody Domain (SCAD)".
|
US4790824A
(en)
|
1987-06-19 |
1988-12-13 |
Bioject, Inc. |
Non-invasive hypodermic injection device
|
US4941880A
(en)
|
1987-06-19 |
1990-07-17 |
Bioject, Inc. |
Pre-filled ampule and non-invasive hypodermic injection device assembly
|
US5892019A
(en)
|
1987-07-15 |
1999-04-06 |
The United States Of America, As Represented By The Department Of Health And Human Services |
Production of a single-gene-encoded immunoglobulin
|
DE3800302A1
(de)
|
1988-01-08 |
1989-07-27 |
Kernforschungsanlage Juelich |
Radiohalogentyrosinderivate, deren herstellung und verwendung
|
US6010902A
(en)
|
1988-04-04 |
2000-01-04 |
Bristol-Meyers Squibb Company |
Antibody heteroconjugates and bispecific antibodies for use in regulation of lymphocyte activity
|
US5215743A
(en)
|
1988-04-13 |
1993-06-01 |
Maninder Singh |
Tumor necrosis factor formulations
|
US5601819A
(en)
|
1988-08-11 |
1997-02-11 |
The General Hospital Corporation |
Bispecific antibodies for selective immune regulation and for selective immune cell binding
|
US5530101A
(en)
|
1988-12-28 |
1996-06-25 |
Protein Design Labs, Inc. |
Humanized immunoglobulins
|
DE3909708A1
(de)
|
1989-03-23 |
1990-09-27 |
Boehringer Mannheim Gmbh |
Verfahren zur herstellung bispezifischer antikoerper
|
US5108921A
(en)
|
1989-04-03 |
1992-04-28 |
Purdue Research Foundation |
Method for enhanced transmembrane transport of exogenous molecules
|
WO1991000360A1
(en)
|
1989-06-29 |
1991-01-10 |
Medarex, Inc. |
Bispecific reagents for aids therapy
|
US5413923A
(en)
|
1989-07-25 |
1995-05-09 |
Cell Genesys, Inc. |
Homologous recombination for universal donor cells and chimeric mammalian hosts
|
US5370870A
(en)
|
1989-10-06 |
1994-12-06 |
Genentech, Inc. |
Method for protection against reactive oxygen species
|
US5064413A
(en)
|
1989-11-09 |
1991-11-12 |
Bioject, Inc. |
Needleless hypodermic injection device
|
US5312335A
(en)
|
1989-11-09 |
1994-05-17 |
Bioject Inc. |
Needleless hypodermic injection device
|
GB8928874D0
(en)
|
1989-12-21 |
1990-02-28 |
Celltech Ltd |
Humanised antibodies
|
US5292658A
(en)
|
1989-12-29 |
1994-03-08 |
University Of Georgia Research Foundation, Inc. Boyd Graduate Studies Research Center |
Cloning and expressions of Renilla luciferase
|
SG48759A1
(en)
|
1990-01-12 |
2002-07-23 |
Abgenix Inc |
Generation of xenogenic antibodies
|
TW212184B
(pt)
|
1990-04-02 |
1993-09-01 |
Takeda Pharm Industry Co Ltd |
|
US5427908A
(en)
|
1990-05-01 |
1995-06-27 |
Affymax Technologies N.V. |
Recombinant library screening methods
|
WO1992000373A1
(en)
|
1990-06-29 |
1992-01-09 |
Biosource Genetics Corporation |
Melanin production by transformed microorganisms
|
GB9015198D0
(en)
|
1990-07-10 |
1990-08-29 |
Brien Caroline J O |
Binding substance
|
US5814318A
(en)
|
1990-08-29 |
1998-09-29 |
Genpharm International Inc. |
Transgenic non-human animals for producing heterologous antibodies
|
US5633425A
(en)
|
1990-08-29 |
1997-05-27 |
Genpharm International, Inc. |
Transgenic non-human animals capable of producing heterologous antibodies
|
US5661016A
(en)
|
1990-08-29 |
1997-08-26 |
Genpharm International Inc. |
Transgenic non-human animals capable of producing heterologous antibodies of various isotypes
|
US5625126A
(en)
|
1990-08-29 |
1997-04-29 |
Genpharm International, Inc. |
Transgenic non-human animals for producing heterologous antibodies
|
US5545806A
(en)
|
1990-08-29 |
1996-08-13 |
Genpharm International, Inc. |
Ransgenic non-human animals for producing heterologous antibodies
|
EP0814159B1
(en)
|
1990-08-29 |
2005-07-27 |
GenPharm International, Inc. |
Transgenic mice capable of producing heterologous antibodies
|
US5283058A
(en)
|
1990-08-30 |
1994-02-01 |
The General Hospital Corporation |
Methods for inhibiting rejection of transplanted tissue
|
ATE160379T1
(de)
|
1990-10-29 |
1997-12-15 |
Chiron Corp |
Bispezifische antikörper, verfahren zu ihrer herstellung und deren verwendungen
|
US5593698A
(en)
|
1990-10-31 |
1997-01-14 |
Autoimmune, Inc. |
Suppression of proliferative response and induction of tolerance with polymorphic class II MHC allopeptides
|
US5582996A
(en)
|
1990-12-04 |
1996-12-10 |
The Wistar Institute Of Anatomy & Biology |
Bifunctional antibodies and method of preparing same
|
US5919452A
(en)
|
1991-03-18 |
1999-07-06 |
New York University |
Methods of treating TNFα-mediated disease using chimeric anti-TNF antibodies
|
EP0519596B1
(en)
|
1991-05-17 |
2005-02-23 |
Merck & Co. Inc. |
A method for reducing the immunogenicity of antibody variable domains
|
DE4118120A1
(de)
|
1991-06-03 |
1992-12-10 |
Behringwerke Ag |
Tetravalente bispezifische rezeptoren, ihre herstellung und verwendung
|
JP4124480B2
(ja)
|
1991-06-14 |
2008-07-23 |
ジェネンテック・インコーポレーテッド |
免疫グロブリン変異体
|
WO1994004679A1
(en)
|
1991-06-14 |
1994-03-03 |
Genentech, Inc. |
Method for making humanized antibodies
|
US5637481A
(en)
|
1993-02-01 |
1997-06-10 |
Bristol-Myers Squibb Company |
Expression vectors encoding bispecific fusion proteins and methods of producing biologically active bispecific fusion proteins in a mammalian cell
|
MX9204374A
(es)
|
1991-07-25 |
1993-03-01 |
Idec Pharma Corp |
Anticuerpo recombinante y metodo para su produccion.
|
DK0600930T3
(da)
|
1991-08-02 |
2002-12-02 |
Denise L Faustman |
Diagnose og behandling af autoimmune sygdomme
|
US6984380B1
(en)
|
1991-08-02 |
2006-01-10 |
Denise L. Faustman |
Treatment of diseases involving faulty MHC class I antigen complex presentation
|
US5139481A
(en)
|
1991-08-07 |
1992-08-18 |
The General Hospital Corporation |
Treatment for type II diabetes
|
WO1993008829A1
(en)
|
1991-11-04 |
1993-05-13 |
The Regents Of The University Of California |
Compositions that mediate killing of hiv-infected cells
|
US5932448A
(en)
|
1991-11-29 |
1999-08-03 |
Protein Design Labs., Inc. |
Bispecific antibody heterodimers
|
ATE408012T1
(de)
|
1991-12-02 |
2008-09-15 |
Medical Res Council |
Herstellung von autoantikörpern auf phagenoberflächen ausgehend von antikörpersegmentbibliotheken
|
US5843425A
(en)
|
1992-02-19 |
1998-12-01 |
The General Hospital Corporation |
Transplantation and graft-versus-host-disease
|
DE4207475A1
(de)
|
1992-03-10 |
1993-09-16 |
Goldwell Ag |
Mittel zum blondieren von menschlichen haaren und verfahren zu dessen herstellung
|
JP3750819B2
(ja)
|
1992-04-23 |
2006-03-01 |
スローン − ケタリング・インスティテュート・フォー・キャンサー・リサーチ |
C−kit受容体に対するリガンド及びその使用法
|
US5383851A
(en)
|
1992-07-24 |
1995-01-24 |
Bioject Inc. |
Needleless hypodermic injection device
|
US5939532A
(en)
|
1993-09-07 |
1999-08-17 |
Kyowa Hakko Kogyo Co., Ltd |
Humanized antibodies to ganglioside GM2
|
US5639641A
(en)
|
1992-09-09 |
1997-06-17 |
Immunogen Inc. |
Resurfacing of rodent antibodies
|
AU5322494A
(en)
|
1992-10-02 |
1994-04-26 |
Trustees Of Dartmouth College |
Bispecific reagents for redirected targeting of low density lipoprotein
|
WO1994009137A1
(en)
|
1992-10-15 |
1994-04-28 |
Genentech, Inc. |
Antibodies against type 2 tumor necrosis factor receptor
|
US5843452A
(en)
|
1992-11-09 |
1998-12-01 |
Pharmagenesis, Inc. |
Immunotherapy composition and method
|
DK0669836T3
(da)
|
1992-11-13 |
1996-10-14 |
Idec Pharma Corp |
Terapeutisk anvendelse af kimære og radioaktivt mærkede antistoffer og humant B-lymfocytbegrænset differentieringsantigen til behandling af B-cellelymfom
|
US5560908A
(en)
|
1993-01-22 |
1996-10-01 |
Kanegafuchi Kagaku Kogyo Kabushiki Kaisha |
Therapeutic agent for NIDDM
|
US5728385A
(en)
|
1993-08-12 |
1998-03-17 |
Classen Immunotherapies, Inc. |
Method and composition for an early vaccine to protect against both common infectious diseases and chronic immune mediated disorders or their sequelae
|
DE4337197C1
(de)
|
1993-10-30 |
1994-08-25 |
Biotest Pharma Gmbh |
Verfahren zur selektiven Herstellung von Hybridomazellinien, die monoklonale Antikörper mit hoher Zytotoxizität gegen humanes CD16-Antigen produzieren, sowie Herstellung bispezifischer monoklonaler Antikörper unter Verwendung derartiger monoklonaler Antikörper und des CD30-HRS-3-Antikörpers zur Therapie menschlicher Tumore
|
CA2183268C
(en)
|
1994-03-07 |
2001-05-15 |
Edward D. Ball |
Bispecific molecules having clinical utilities
|
US5693617A
(en)
|
1994-03-15 |
1997-12-02 |
Proscript, Inc. |
Inhibitors of the 26s proteolytic complex and the 20s proteasome contained therein
|
US6660268B1
(en)
|
1994-03-18 |
2003-12-09 |
The President And Fellows Of Harvard College |
Proteasome regulation of NF-KB activity
|
US5874301A
(en)
|
1994-11-21 |
1999-02-23 |
National Jewish Center For Immunology And Respiratory Medicine |
Embryonic cell populations and methods to isolate such populations
|
US5670356A
(en)
|
1994-12-12 |
1997-09-23 |
Promega Corporation |
Modified luciferase
|
US5731168A
(en)
|
1995-03-01 |
1998-03-24 |
Genentech, Inc. |
Method for making heteromultimeric polypeptides
|
US6037453A
(en)
|
1995-03-15 |
2000-03-14 |
Genentech, Inc. |
Immunoglobulin variants
|
US5739277A
(en)
|
1995-04-14 |
1998-04-14 |
Genentech Inc. |
Altered polypeptides with increased half-life
|
US6121022A
(en)
|
1995-04-14 |
2000-09-19 |
Genentech, Inc. |
Altered polypeptides with increased half-life
|
US5869046A
(en)
|
1995-04-14 |
1999-02-09 |
Genentech, Inc. |
Altered polypeptides with increased half-life
|
CA2219361C
(en)
|
1995-04-27 |
2012-02-28 |
Abgenix, Inc. |
Human antibodies derived from immunized xenomice
|
AU2466895A
(en)
|
1995-04-28 |
1996-11-18 |
Abgenix, Inc. |
Human antibodies derived from immunized xenomice
|
WO1997002342A1
(en)
|
1995-06-30 |
1997-01-23 |
Københavns Universitet |
Recombinant antibodies from a phage display library, directed against a peptide-mhc complex
|
US6056952A
(en)
|
1995-08-30 |
2000-05-02 |
The United States Of America As Represented By The Department Of Health And Human Services |
Selective elimination of T cells that recognize specific preselected targets
|
US5801030A
(en)
|
1995-09-01 |
1998-09-01 |
Genvec, Inc. |
Methods and vectors for site-specific recombination
|
GB9601081D0
(en)
*
|
1995-10-06 |
1996-03-20 |
Cambridge Antibody Tech |
Specific binding members for human transforming growth factor beta;materials and methods
|
EP0826695B1
(de)
|
1996-09-03 |
2001-12-12 |
GSF-Forschungszentrum für Umwelt und Gesundheit GmbH |
Zerstörung von kontaminierenden Tumorzellen in Stammzelltransplantaten mit bispezifischen Antikörpern
|
US5916771A
(en)
|
1996-10-11 |
1999-06-29 |
Abgenix, Inc. |
Production of a multimeric protein by cell fusion method
|
KR100942002B1
(ko)
|
1996-12-03 |
2010-02-12 |
암젠 프레몬트 인코포레이티드 |
복수의 vh 및 vk 부위를 함유하는 사람 면역글로불린 유전자좌를 갖는 형질전환된 포유류 및 이로부터 생성된 항체
|
US5874306A
(en)
|
1996-12-12 |
1999-02-23 |
The Regents Of The University Of California |
Culturing human pancreatic endocrine cells in medium containing extracellular matrix from human bladder carcinoma cells
|
AU6241698A
(en)
|
1997-01-21 |
1998-08-07 |
Human Genome Sciences, Inc. |
Tace-like and matrilysin-like polypeptides
|
BRPI9809391B8
(pt)
|
1997-04-14 |
2021-05-25 |
Amgen Res Munich Gmbh |
processo para a produção de um receptor de antígeno anti-humano, anticorpo humano e composição farmacêutica
|
US6235883B1
(en)
|
1997-05-05 |
2001-05-22 |
Abgenix, Inc. |
Human monoclonal antibodies to epidermal growth factor receptor
|
DE69833755T2
(de)
|
1997-05-21 |
2006-12-28 |
Biovation Ltd. |
Verfahren zur herstellung von nicht-immunogenen proteinen
|
US6177076B1
(en)
|
1997-12-09 |
2001-01-23 |
Thomas Jefferson University |
Method of treating bladder cancer with wild type vaccinia virus
|
US6171809B1
(en)
|
1998-01-29 |
2001-01-09 |
Packard Instrument Company |
Method and compositions for detecting luciferase biological samples
|
US6617171B2
(en)
|
1998-02-27 |
2003-09-09 |
The General Hospital Corporation |
Methods for diagnosing and treating autoimmune disease
|
US6165737A
(en)
|
1998-04-16 |
2000-12-26 |
The University Of Texas System Board Of Regents |
DNA fragmentation factor involved in apoptosis
|
US6284879B1
(en)
|
1998-04-16 |
2001-09-04 |
The General Hospital Corporation |
Transport associated protein splice variants
|
EP1077724A2
(en)
|
1998-04-17 |
2001-02-28 |
The University Of Vermont |
Methods and products related to metabolic interactions in disease
|
IL139574A0
(en)
|
1998-05-18 |
2002-02-10 |
Applied Research Systems |
TNF-RII (p75) AGONISTS FOR TREATING ASTHMA AND OTHER ALLERGIC CONDITIONS
|
EP1137941B2
(en)
|
1998-12-10 |
2013-09-11 |
Bristol-Myers Squibb Company |
Protein scaffolds for antibody mimics and other binding proteins
|
US7485293B1
(en)
|
1999-02-18 |
2009-02-03 |
Faustman Denise L |
Method for inhibiting transplant rejection
|
US6599710B1
(en)
|
1999-03-10 |
2003-07-29 |
The General Hospital Corporation |
Treatment of autoimmune disease
|
US7015037B1
(en)
|
1999-08-05 |
2006-03-21 |
Regents Of The University Of Minnesota |
Multiponent adult stem cells and methods for isolation
|
JP3589912B2
(ja)
|
1999-09-03 |
2004-11-17 |
泰久 福井 |
ホスファチジルイノシトール−3,4−二リン酸を認識するモノクローナル抗体
|
IL149933A0
(en)
|
1999-12-06 |
2002-11-10 |
Gen Hospital Corp |
Pancreatic stem cells and their use in transplantation
|
AU2262501A
(en)
|
1999-12-16 |
2001-06-25 |
Amgen, Inc. |
Tnfr/opg-like molecules and uses thereof
|
US6414218B1
(en)
|
2000-01-18 |
2002-07-02 |
The General Hospital Corporation |
Mouse model for rheumatoid arthritis
|
ES2253358T3
(es)
|
2000-03-31 |
2006-06-01 |
Cambridge Antibody Technology Limited |
Mejoras en la visualizacion del ribosoma.
|
WO2001081565A2
(de)
|
2000-04-27 |
2001-11-01 |
Max-Delbrück-Centrum für Molekulare Medizin |
Sleeping beauty, ein transposonvektor mit breitem wirtsbereich für die genetische transformation bei wirbeltieren
|
WO2001091793A1
(en)
*
|
2000-05-26 |
2001-12-06 |
Smithkline Beecham Corporation |
Anti-rank ligand monoclonal antibodies useful in treatment of rank ligand mediated disorders
|
AU2001294834A1
(en)
|
2000-09-26 |
2002-04-08 |
Beth Israel Deaconess Medical Center |
Recombinant bcg vaccines for the prevention and treatment of cancer
|
US20040031066A9
(en)
|
2001-01-18 |
2004-02-12 |
Faustman Denise L. |
Mouse model for rheumatoid arthritis
|
EP1539233B1
(en)
|
2001-07-12 |
2011-04-27 |
FOOTE, Jefferson |
Super humanized antibodies
|
WO2003033521A1
(en)
|
2001-10-16 |
2003-04-24 |
Massachusetts Institute Of Technology |
Inppressor trna system in mammalian cells for the introduction of unnatural amino acids in polypeptides.
|
US20030206898A1
(en)
*
|
2002-04-26 |
2003-11-06 |
Steven Fischkoff |
Use of anti-TNFalpha antibodies and another drug
|
WO2003105782A2
(en)
|
2002-06-17 |
2003-12-24 |
The Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services |
Specificity grafting of a murine antibody onto a human framework
|
US7582313B2
(en)
|
2002-06-27 |
2009-09-01 |
The General Hospital Corporation |
Methods of organ regeneration using Hox 11-expressing pluripotent cells
|
US7628988B2
(en)
|
2002-06-27 |
2009-12-08 |
The General Hospital Corporation |
Methods and compositions for treating type 1 diabetes
|
WO2004045376A2
(en)
|
2002-11-15 |
2004-06-03 |
The General Hospital Corporation |
Screening methods to identify treatments for autoimmune disease
|
ATE472556T1
(de)
*
|
2002-12-02 |
2010-07-15 |
Amgen Fremont Inc |
Gegen den tumor nekrose faktor gerichtete antikörper und deren verwendungen
|
US7413874B2
(en)
|
2002-12-09 |
2008-08-19 |
University Of Miami |
Nucleic acid encoding fluorescent proteins from aquatic species
|
US20040142379A1
(en)
|
2003-01-16 |
2004-07-22 |
Carlsberg Research Laboratory |
Affinity fishing for ligands and proteins receptors
|
WO2005030040A2
(en)
|
2003-09-26 |
2005-04-07 |
The Regents Of The University Of Michigan |
Hematopoietic stem cell identification and isolation
|
US7183092B2
(en)
|
2003-10-03 |
2007-02-27 |
Board Of Control Of Michigan Technological University |
Modified luciferase
|
US20090028877A1
(en)
|
2003-10-09 |
2009-01-29 |
Shigeru Iida |
Antibody Composition Specifically Binding to Ganglioside Gm
|
US8563308B2
(en)
|
2004-03-10 |
2013-10-22 |
The Rockefeller University |
Culture-expanded T suppressor cells and methods of use thereof
|
EP3363907A1
(en)
|
2004-05-27 |
2018-08-22 |
The Trustees of the University of Pennsylvania |
Novel artificial antigen presenting cells and uses therefor
|
US20060024667A1
(en)
|
2004-07-29 |
2006-02-02 |
Karen Manucharyan |
Compositions and methods for Alzheimer's disease
|
GB0500099D0
(en)
|
2005-01-05 |
2005-02-09 |
Cambridge Antibody Tech |
Methods and means relating to protein variants
|
US20080102054A1
(en)
|
2005-01-18 |
2008-05-01 |
Faustman Denise L |
Compositions Containing Agm Cells And Methods Of Use Thereof
|
CA2605253C
(en)
|
2005-04-11 |
2017-06-13 |
Yale University |
Selective modulation of tumour necrosis factor receptors in therapy
|
JP2009504685A
(ja)
|
2005-08-15 |
2009-02-05 |
アラーナ・テラピューティクス・リミテッド |
新世界霊長類フレームワーク領域を用いる設計された抗体
|
US7422899B2
(en)
|
2005-10-05 |
2008-09-09 |
Biogen Idec Ma Inc. |
Antibodies to the human prolactin receptor
|
EP2360244B1
(en)
|
2005-10-18 |
2014-12-24 |
Precision Biosciences |
Rationally-designed meganucleases with altered sequence specificity and DNA-binding affinity
|
RU2412250C2
(ru)
|
2005-11-04 |
2011-02-20 |
Закрытое акционерное общество "ЕВРОГЕН" |
Модифицированные зеленые флуоресцентные белки и способы их использования
|
HUE029919T2
(en)
|
2006-02-02 |
2017-04-28 |
Massachusetts Gen Hospital |
Genetically modified antibody stress protein fusions
|
EP2639242A3
(en)
|
2006-03-06 |
2013-10-16 |
MedImmune, Inc. |
Humanized anti-CD22 antibodies and their use in treatment of oncology, transplantation and autoimmune disease
|
JP2007306828A
(ja)
|
2006-05-17 |
2007-11-29 |
Tokai Univ |
非還元マンノース残基を認識するファージ提示型単鎖抗体
|
CA2659225A1
(en)
|
2006-07-26 |
2008-01-31 |
Pepscan Systems B.V. |
Immunogenic compounds and protein mimics
|
PT2094728E
(pt)
|
2006-10-26 |
2013-05-27 |
Janssen Biotech Inc |
Métodos de adaptação de anticorpos monoclonais ao ser humano
|
WO2008090960A1
(ja)
|
2007-01-24 |
2008-07-31 |
Kyowa Hakko Kirin Co., Ltd. |
ガングリオシドgm2に特異的に結合する遺伝子組換え抗体組成物
|
WO2008157394A2
(en)
|
2007-06-13 |
2008-12-24 |
La Jolla Institute For Allergy And Immunology |
Regulatory t cells and methods of making and using same
|
WO2009002380A2
(en)
|
2007-06-26 |
2008-12-31 |
The Trustees Of The University Of Pennsylvania |
Isolation of anti-desmoglein 1 antibodies by phage display of pemphigus foliaceus autoantibodies
|
US8900816B2
(en)
|
2007-07-19 |
2014-12-02 |
Duke University |
Assay for anti-EGFRvIII antibodies
|
WO2009059195A2
(en)
|
2007-10-31 |
2009-05-07 |
Precision Biosciences |
Rationally-designed single-chain meganucleases with non-palindromic recognition sequences
|
JP2011507529A
(ja)
|
2007-12-19 |
2011-03-10 |
セントコア・オーソ・バイオテツク・インコーポレーテツド |
M13ファージのpIXへの融合を介する代替の足場タンパク質融合ファージ提示
|
EP2280997A2
(en)
|
2008-04-18 |
2011-02-09 |
Xencor, Inc. |
Human equivalent monoclonal antibodies engineered from nonhuman variable regions
|
EP2799448A1
(en)
|
2008-05-22 |
2014-11-05 |
Bristol-Myers Squibb Company |
Multivalent fibronectin based scaffold domain proteins
|
ES2705714T3
(es)
|
2008-10-31 |
2019-03-26 |
Janssen Biotech Inc |
Métodos y usos de dominio de Fibronectina tipo III basado en estructuras de composiciones
|
WO2010085699A2
(en)
|
2009-01-23 |
2010-07-29 |
The Johns Hopkins University |
Mammalian piggybac transposon and methods of use
|
AU2010237046B2
(en)
|
2009-04-17 |
2015-06-04 |
New York University |
Peptides targeting TNF family receptors and antagonizing TNF action, compositions, methods and uses thereof
|
WO2010124262A1
(en)
|
2009-04-24 |
2010-10-28 |
Allostera Pharma Inc. |
Methods of identification of allosteramers and uses thereof
|
EP2445503A1
(en)
|
2009-04-28 |
2012-05-02 |
Boehringer Ingelheim International GmbH |
Ex-vivo treatment of immunological disorders with pkc-theta inhibitors
|
EP2431463A4
(en)
|
2009-05-13 |
2012-12-26 |
Shionogi & Co |
TESTS FOR VISCERAL ADIPOSITAS AND ITS USE
|
WO2011084714A2
(en)
|
2009-12-17 |
2011-07-14 |
Biogen Idec Ma Inc. |
STABILIZED ANTI-TNF-ALPHA scFv MOLECULES OR ANTI-TWEAK scFv MOLECULES AND USES THEREOF
|
EP2571577A1
(en)
|
2010-05-17 |
2013-03-27 |
Bristol-Myers Squibb Company |
Improved immunotherapeutic dosing regimens and combinations thereof
|
PL2616489T3
(pl)
*
|
2010-09-16 |
2017-07-31 |
Baliopharm Ag |
Przeciwciało anty-huTNFR1
|
US20140121123A1
(en)
*
|
2010-10-29 |
2014-05-01 |
Kevin Caili Wang |
Methods for diversifying antibodies, antibodies derived therefrom and uses thereof
|
AU2011338200B2
(en)
|
2010-12-09 |
2017-02-23 |
The Trustees Of The University Of Pennsylvania |
Use of chimeric antigen receptor-modified T cells to treat cancer
|
EP2655411A1
(en)
|
2010-12-22 |
2013-10-30 |
Bristol-Myers Squibb Company |
Fibronectin based scaffold domain proteins that bind il-23
|
EP2468764A1
(en)
|
2010-12-24 |
2012-06-27 |
Rijksuniversiteit te Groningen |
TNF family ligand variants
|
WO2012122464A1
(en)
|
2011-03-10 |
2012-09-13 |
New York University |
Methods and compositions for modulating tnf/tnfr signaling
|
GB201115280D0
(en)
*
|
2011-09-05 |
2011-10-19 |
Alligator Bioscience Ab |
Antibodies, uses and methods
|
US20130085072A1
(en)
|
2011-10-03 |
2013-04-04 |
Los Alamos National Security, Llc |
Recombinant renewable polyclonal antibodies
|
AU2013312838B2
(en)
|
2012-09-04 |
2018-11-29 |
Cellectis |
Multi-chain chimeric antigen receptor and uses thereof
|
US8697359B1
(en)
|
2012-12-12 |
2014-04-15 |
The Broad Institute, Inc. |
CRISPR-Cas systems and methods for altering expression of gene products
|
US20150329640A1
(en)
|
2012-12-20 |
2015-11-19 |
Bluebird Bio, Inc. |
Chimeric antigen receptors and immune cells targeting b cell malignancies
|
DK2953634T3
(da)
*
|
2013-02-07 |
2021-08-30 |
Massachusetts Gen Hospital |
Fremgangsmåder til udvidelse eller udtømning af regulerende t-celler
|
KR102332790B1
(ko)
|
2013-02-15 |
2021-12-01 |
더 리젠츠 오브 더 유니버시티 오브 캘리포니아 |
키메라 항원 수용체 및 이의 이용 방법
|
WO2014152660A1
(en)
|
2013-03-15 |
2014-09-25 |
The Regents Of The University Of California |
Engineered antibody scaffolds
|
WO2015145360A1
(en)
|
2014-03-24 |
2015-10-01 |
Glennie Martin J |
Modified antibodies containing modified igg2 domains which elicit agonist or antagonistic properties and use thereof
|
EP4292664A3
(en)
|
2015-05-15 |
2024-06-12 |
The General Hospital Corporation |
Antagonistic anti-tumor necrosis factor receptor superfamily antibodies
|
EP3340999A4
(en)
|
2015-08-28 |
2019-06-12 |
The General Hospital Corporation |
TYPE II ANTI-RECEPTOR AGONISTIC ANTIBODIES OF TUMOR NECROSIS FACTOR
|
WO2017083525A1
(en)
|
2015-11-11 |
2017-05-18 |
Opi Vi- Ip Holdco Llc |
Composition and methods for anti-tnfr2 antibodies
|