PT3430141T - Oligonucleótidos para redução da expressão de pd-l1 - Google Patents

Oligonucleótidos para redução da expressão de pd-l1

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Publication number
PT3430141T
PT3430141T PT177108743T PT17710874T PT3430141T PT 3430141 T PT3430141 T PT 3430141T PT 177108743 T PT177108743 T PT 177108743T PT 17710874 T PT17710874 T PT 17710874T PT 3430141 T PT3430141 T PT 3430141T
Authority
PT
Portugal
Prior art keywords
oligonucleotides
expression
reduction
Prior art date
Application number
PT177108743T
Other languages
English (en)
Portuguese (pt)
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of PT3430141T publication Critical patent/PT3430141T/pt

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    • C12N15/113Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C12N15/1138Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against receptors or cell surface proteins
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PT177108743T 2016-03-14 2017-03-14 Oligonucleótidos para redução da expressão de pd-l1 PT3430141T (pt)

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KR101881596B1 (ko) 2008-12-02 2018-07-24 웨이브 라이프 사이언시스 재팬 인코포레이티드 인 원자 변형된 핵산의 합성 방법
RU2612521C2 (ru) 2009-07-06 2017-03-09 Онтории, Инк. Новые пролекарства нуклеиновых кислот и способы их применения
JP5868324B2 (ja) 2010-09-24 2016-02-24 株式会社Wave Life Sciences Japan 不斉補助基
BR112014001244A2 (pt) 2011-07-19 2017-02-21 Wave Life Sciences Pte Ltd métodos para a síntese de ácidos nucléicos funcionalizados
CN112007045A (zh) 2012-07-13 2020-12-01 波涛生命科学有限公司 手性控制
ES2862073T3 (es) 2012-07-13 2021-10-06 Wave Life Sciences Ltd Grupo auxiliar asimétrico
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TW202128998A (zh) 2021-08-01
WO2017157899A1 (en) 2017-09-21
HUE053172T2 (hu) 2021-06-28
AR118719A2 (es) 2021-10-27
CA3120687A1 (en) 2017-09-21
KR20210120131A (ko) 2021-10-06
JP7002603B2 (ja) 2022-02-10
CN108779465B (zh) 2022-05-13
IL296483B2 (en) 2023-10-01
JP2022034059A (ja) 2022-03-02
TWI794662B (zh) 2023-03-01
MY194912A (en) 2022-12-22
CR20200119A (es) 2021-04-19
NZ744548A (en) 2024-05-31
KR20180120702A (ko) 2018-11-06
RU2018134379A (ru) 2020-04-15

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