PT3113782T - Sistemas e métodos de administração de fármaco para tratamento do cancro da bexiga com gemcitabina - Google Patents
Sistemas e métodos de administração de fármaco para tratamento do cancro da bexiga com gemcitabinaInfo
- Publication number
- PT3113782T PT3113782T PT157113739T PT15711373T PT3113782T PT 3113782 T PT3113782 T PT 3113782T PT 157113739 T PT157113739 T PT 157113739T PT 15711373 T PT15711373 T PT 15711373T PT 3113782 T PT3113782 T PT 3113782T
- Authority
- PT
- Portugal
- Prior art keywords
- gemcitabine
- treatment
- methods
- drug delivery
- delivery systems
- Prior art date
Links
- 206010005003 Bladder cancer Diseases 0.000 title 1
- 208000007097 Urinary Bladder Neoplasms Diseases 0.000 title 1
- 238000012377 drug delivery Methods 0.000 title 1
- SDUQYLNIPVEERB-QPPQHZFASA-N gemcitabine Chemical compound O=C1N=C(N)C=CN1[C@H]1C(F)(F)[C@H](O)[C@@H](CO)O1 SDUQYLNIPVEERB-QPPQHZFASA-N 0.000 title 1
- 229960005277 gemcitabine Drugs 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 201000005112 urinary bladder cancer Diseases 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
- A61K9/0004—Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0092—Hollow drug-filled fibres, tubes of the core-shell type, coated fibres, coated rods, microtubules or nanotubes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
- A61M31/002—Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Reproductive Health (AREA)
- Gynecology & Obstetrics (AREA)
- Dermatology (AREA)
- Neurosurgery (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Anesthesiology (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Nanotechnology (AREA)
- Hematology (AREA)
- Biochemistry (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Media Introduction/Drainage Providing Device (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201461949215P | 2014-03-06 | 2014-03-06 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT3113782T true PT3113782T (pt) | 2023-01-05 |
Family
ID=52697553
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT157113739T PT3113782T (pt) | 2014-03-06 | 2015-03-06 | Sistemas e métodos de administração de fármaco para tratamento do cancro da bexiga com gemcitabina |
| PT221965965T PT4124339T (pt) | 2014-03-06 | 2015-03-06 | Sistemas e métodos de administração de fármacos para o tratamento do cancro da bexiga com gemcitabina |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT221965965T PT4124339T (pt) | 2014-03-06 | 2015-03-06 | Sistemas e métodos de administração de fármacos para o tratamento do cancro da bexiga com gemcitabina |
Country Status (24)
| Country | Link |
|---|---|
| US (3) | US20150250717A1 (enExample) |
| EP (2) | EP4124339B1 (enExample) |
| JP (5) | JP6901858B2 (enExample) |
| KR (1) | KR102338079B1 (enExample) |
| CN (2) | CN119950539A (enExample) |
| AU (4) | AU2015226901B2 (enExample) |
| BR (1) | BR112016020381A8 (enExample) |
| CA (1) | CA2939979C (enExample) |
| DK (2) | DK3113782T3 (enExample) |
| ES (2) | ES3051417T3 (enExample) |
| FI (1) | FI4124339T3 (enExample) |
| HR (2) | HRP20251264T1 (enExample) |
| HU (1) | HUE060704T2 (enExample) |
| IL (2) | IL311410B2 (enExample) |
| LT (2) | LT3113782T (enExample) |
| MX (1) | MX2016011333A (enExample) |
| PL (2) | PL3113782T3 (enExample) |
| PT (2) | PT3113782T (enExample) |
| RS (2) | RS63675B1 (enExample) |
| RU (1) | RU2694902C1 (enExample) |
| SG (2) | SG10202101978SA (enExample) |
| SI (1) | SI4124339T1 (enExample) |
| SM (2) | SMT202200449T1 (enExample) |
| WO (1) | WO2015134911A1 (enExample) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2014036556A2 (en) | 2012-08-31 | 2014-03-06 | Taris Biomedical, Inc. | Drug delivery systems and methods for treatment of prostate |
| IL299897B2 (en) | 2013-08-19 | 2024-02-01 | Taris Biomedical Llc | Devices and methods for administering multiple units of drug |
| PT3113782T (pt) | 2014-03-06 | 2023-01-05 | Taris Biomedical Llc | Sistemas e métodos de administração de fármaco para tratamento do cancro da bexiga com gemcitabina |
| SG11201809838VA (en) * | 2016-05-06 | 2018-12-28 | Taris Biomedical Llc | Method of treating lower tract urothelial cancer |
| US10857173B2 (en) * | 2017-07-25 | 2020-12-08 | Taris Biomedical Llc | Methods of treating tumor metastasis |
| KR102892737B1 (ko) * | 2017-11-08 | 2025-11-28 | 타리스 바이오메디컬 엘엘씨 | 젬시타빈을 사용한 방광암의 치료 및 유지 요법의 방법 |
| AU2019315957A1 (en) | 2018-08-01 | 2021-02-18 | Taris Biomedical Llc | Methods of treating overactive bladder using trospium |
| JP7660066B2 (ja) * | 2019-10-03 | 2025-04-10 | 生化学工業株式会社 | 膀胱の粘膜下組織への医薬品有効成分の経粘膜的送達システム |
| RU2713443C2 (ru) * | 2019-11-01 | 2020-02-05 | Федеральное государственное бюджетное учреждение "Национальный медицинский исследовательский центр радиологии" Министерства здравоохранения Российской Федерации (ФГБУ "НМИЦ радиологии" Минздрава России) | Способ комбинированного лечения мышечно-инвазивного рака мочевого пузыря т3-т4 n0-+m0 |
| JP2023512652A (ja) * | 2020-01-27 | 2023-03-28 | アイソラ セラピューティクス，インコーポレイテッド | 管腔内局所薬剤送達のための組織内投与 |
| CN112169066B (zh) * | 2020-10-29 | 2023-05-12 | 安徽省立医院(中国科学技术大学附属第一医院) | 具有控制器的连续缓释给药留置管 |
| CN113616666A (zh) * | 2021-08-24 | 2021-11-09 | 傅广波 | 膀胱黏膜下注射吉西他滨在治疗膀胱癌中的应用 |
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| US4111203A (en) * | 1976-11-22 | 1978-09-05 | Alza Corporation | Osmotic system with means for improving delivery kinetics of system |
| US6171298B1 (en) | 1996-05-03 | 2001-01-09 | Situs Corporation | Intravesical infuser |
| CA2432438C (en) | 2001-01-09 | 2011-04-26 | Microchips, Inc. | Flexible microchip devices for ophthalmic and other applications |
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| EP1933810B1 (en) | 2005-08-11 | 2012-10-10 | Massachusetts Institute of Technology | Intravesical drug delivery device and method |
| CA2649877A1 (en) * | 2006-04-24 | 2007-12-21 | Gloucester Pharmaceuticals | Gemcitabine combination therapy |
| EP1913962A1 (en) | 2006-10-22 | 2008-04-23 | Ophir Perelson | Expandable medical device for the treatment and prevention of cardiovascular diseases |
| EA201070703A1 (ru) | 2007-12-11 | 2010-12-30 | Массачусетс Инститьют Оф Текнолоджи | Имплантируемое устройство для доставки лекарства и способы лечения мочевого пузыря и других полостей тела или трубчатых органов |
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| US9017312B2 (en) | 2009-09-10 | 2015-04-28 | Taris Biomedical Llc | Implantable device for controlled drug delivery |
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| EP2525777B1 (en) * | 2010-01-20 | 2019-05-29 | UroGen Pharma Ltd. | Material and method for treating internal cavities |
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| US9492266B2 (en) | 2010-08-05 | 2016-11-15 | Taris Biomedical Llc | Ureteral stent drug delivery device, kit, and method |
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| KR20190134832A (ko) | 2012-03-29 | 2019-12-04 | 알토 바이오사이언스 코포레이션 | 종양 형성 치료방법 |
| US10058688B2 (en) | 2012-05-09 | 2018-08-28 | Massachusetts Institute Of Technology | Medicament, method, and drug delivery device for treatment of ovarian cancer |
| WO2014036556A2 (en) * | 2012-08-31 | 2014-03-06 | Taris Biomedical, Inc. | Drug delivery systems and methods for treatment of prostate |
| PL2890384T3 (pl) | 2012-08-31 | 2022-02-14 | Taris Biomedical Llc | Układy podawania leku i sposoby leczenia raka pęcherza obejmujące oksaliplatynę |
| EP2897616A1 (en) | 2012-09-18 | 2015-07-29 | TARIS Biomedical LLC | Drug delivery systems and methods for treatment of bladder voiding dysfunction!and other lower urinary tract disorders by using trospium |
| JP2016508842A (ja) | 2013-03-05 | 2016-03-24 | タリス バイオメディカル エルエルシー | 装置の開口部を通じて制御された薬物放出のための薬物送達装置及び方法 |
| PL2968880T3 (pl) | 2013-03-15 | 2025-06-23 | Taris Biomedical Llc | Urządzenia do dostarczania leku ze składnikiem przepuszczalnym dla leku |
| MX391755B (es) | 2013-03-15 | 2025-03-21 | Taris Biomedical Llc | Dispositivos de administración de medicamentos y métodos para administración de medicamentos. |
| JP6431528B2 (ja) | 2013-04-10 | 2018-11-28 | マサチューセッツ インスチテュート オブ テクノロジーＭａｓｓａｃｈｕｓｅｔｔｓ Ｉｎｓｔｉｔｕｔｅ Ｏｆ Ｔｅｃｈｎｏｌｏｇｙ | 癌治療のための薬物局所送達装置及び方法 |
| IL299897B2 (en) * | 2013-08-19 | 2024-02-01 | Taris Biomedical Llc | Devices and methods for administering multiple units of drug |
| BR112016010103A8 (pt) * | 2013-11-05 | 2018-01-30 | Taris Biomedical Llc | métodos, kits e dispositivos de suprimento de fármaco osmótico. |
| PT3113782T (pt) | 2014-03-06 | 2023-01-05 | Taris Biomedical Llc | Sistemas e métodos de administração de fármaco para tratamento do cancro da bexiga com gemcitabina |
| RU2591946C2 (ru) | 2014-06-24 | 2016-07-20 | Владимир Эдуардович Анников | Способ изготовления гелеобразного водосодержащего взрывчатого состава |
| KR20230142816A (ko) | 2014-06-26 | 2023-10-11 | 타리스 바이오메디컬 엘엘씨 | 탄성 폴리머-약물 매트릭스 시스템을 포함하는 방광내 약물 전달 장치 및 방법 |
| EP4744688A2 (en) | 2015-04-23 | 2026-05-20 | Janssen Biotech Inc | DRUG DELIVERY DEVICES WITH A DRUG-PERMEABLE COMPONENT AND METHODS |
| SG11201809838VA (en) | 2016-05-06 | 2018-12-28 | Taris Biomedical Llc | Method of treating lower tract urothelial cancer |
| US10857173B2 (en) | 2017-07-25 | 2020-12-08 | Taris Biomedical Llc | Methods of treating tumor metastasis |
| KR102892737B1 (ko) | 2017-11-08 | 2025-11-28 | 타리스 바이오메디컬 엘엘씨 | 젬시타빈을 사용한 방광암의 치료 및 유지 요법의 방법 |
| AU2019315957A1 (en) | 2018-08-01 | 2021-02-18 | Taris Biomedical Llc | Methods of treating overactive bladder using trospium |
-
2015
- 2015-03-06 PT PT157113739T patent/PT3113782T/pt unknown
- 2015-03-06 CN CN202510128139.2A patent/CN119950539A/zh active Pending
- 2015-03-06 SM SM20220449T patent/SMT202200449T1/it unknown
- 2015-03-06 RS RS20220937A patent/RS63675B1/sr unknown
- 2015-03-06 JP JP2016555554A patent/JP6901858B2/ja active Active
- 2015-03-06 SM SM20250385T patent/SMT202500385T1/it unknown
- 2015-03-06 EP EP22196596.5A patent/EP4124339B1/en active Active
- 2015-03-06 CA CA2939979A patent/CA2939979C/en active Active
- 2015-03-06 RS RS20251017A patent/RS67337B1/sr unknown
- 2015-03-06 ES ES22196596T patent/ES3051417T3/es active Active
- 2015-03-06 LT LTEPPCT/US2015/019262T patent/LT3113782T/lt unknown
- 2015-03-06 EP EP15711373.9A patent/EP3113782B1/en active Active
- 2015-03-06 US US14/641,009 patent/US20150250717A1/en not_active Abandoned
- 2015-03-06 FI FIEP22196596.5T patent/FI4124339T3/fi active
- 2015-03-06 CN CN201580011259.9A patent/CN106102751A/zh active Pending
- 2015-03-06 LT LTEP22196596.5T patent/LT4124339T/lt unknown
- 2015-03-06 PT PT221965965T patent/PT4124339T/pt unknown
- 2015-03-06 SI SI201532080T patent/SI4124339T1/sl unknown
- 2015-03-06 KR KR1020167027303A patent/KR102338079B1/ko active Active
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- 2015-03-06 PL PL15711373.9T patent/PL3113782T3/pl unknown
- 2015-03-06 RU RU2016136103A patent/RU2694902C1/ru active
- 2015-03-06 BR BR112016020381A patent/BR112016020381A8/pt not_active Application Discontinuation
- 2015-03-06 HR HRP20251264TT patent/HRP20251264T1/hr unknown
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- 2015-03-06 WO PCT/US2015/019262 patent/WO2015134911A1/en not_active Ceased
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2019
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