PT2621891T - Polimorfos de cloridrato de 4-metilbenzoato de 4-[2- dimetilamino-1-(1-hidroxiciclohexil)etil]fenilo, métodos para a preparação dos mesmos e utilização dos mesmos - Google Patents
Polimorfos de cloridrato de 4-metilbenzoato de 4-[2- dimetilamino-1-(1-hidroxiciclohexil)etil]fenilo, métodos para a preparação dos mesmos e utilização dos mesmosInfo
- Publication number
- PT2621891T PT2621891T PT118279116T PT11827911T PT2621891T PT 2621891 T PT2621891 T PT 2621891T PT 118279116 T PT118279116 T PT 118279116T PT 11827911 T PT11827911 T PT 11827911T PT 2621891 T PT2621891 T PT 2621891T
- Authority
- PT
- Portugal
- Prior art keywords
- same
- hydroxycyclohexyl
- polymorphs
- dimethylamino
- phenyl
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
- C07C215/46—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
- C07C215/64—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with rings other than six-membered aromatic rings being part of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C219/00—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C219/26—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
- C07C219/28—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton having amino groups bound to acyclic carbon atoms of the carbon skeleton
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
-
- A—HUMAN NECESSITIES
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- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
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- A61P3/02—Nutrients, e.g. vitamins, minerals
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P9/08—Vasodilators for multiple indications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C213/10—Separation; Purification; Stabilisation; Use of additives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
- C07C215/02—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C215/04—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated
- C07C215/20—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated the carbon skeleton being saturated and containing rings
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Psychiatry (AREA)
- Addiction (AREA)
- Reproductive Health (AREA)
- Endocrinology (AREA)
- Pain & Pain Management (AREA)
- Urology & Nephrology (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Emergency Medicine (AREA)
- Epidemiology (AREA)
- Cardiology (AREA)
- Nutrition Science (AREA)
- Heart & Thoracic Surgery (AREA)
- Gynecology & Obstetrics (AREA)
- Hospice & Palliative Care (AREA)
- Rheumatology (AREA)
- Anesthesiology (AREA)
- Psychology (AREA)
- Physical Education & Sports Medicine (AREA)
- Child & Adolescent Psychology (AREA)
- Toxicology (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201010503737 | 2010-10-01 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT2621891T true PT2621891T (pt) | 2020-02-04 |
Family
ID=45891856
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT118279116T PT2621891T (pt) | 2010-10-01 | 2011-09-28 | Polimorfos de cloridrato de 4-metilbenzoato de 4-[2- dimetilamino-1-(1-hidroxiciclohexil)etil]fenilo, métodos para a preparação dos mesmos e utilização dos mesmos |
Country Status (17)
| Country | Link |
|---|---|
| US (2) | US8741952B2 (zh) |
| EP (1) | EP2621891B1 (zh) |
| JP (7) | JP2014500234A (zh) |
| KR (3) | KR101477154B1 (zh) |
| CN (3) | CN103588652B (zh) |
| AU (1) | AU2011307952B2 (zh) |
| BR (3) | BR112013008664B1 (zh) |
| CA (3) | CA2812227C (zh) |
| CY (1) | CY1122772T1 (zh) |
| DK (1) | DK2621891T3 (zh) |
| ES (1) | ES2769581T3 (zh) |
| MY (1) | MY160607A (zh) |
| PL (1) | PL2621891T3 (zh) |
| PT (1) | PT2621891T (zh) |
| RU (1) | RU2576665C2 (zh) |
| SG (1) | SG188637A1 (zh) |
| WO (1) | WO2012041013A1 (zh) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104672097B (zh) * | 2013-12-03 | 2016-06-29 | 山东绿叶制药有限公司 | 化合物对甲基苯甲酸4-（2-二甲胺基-1-环己烯基乙基）苯酯制备方法及应用 |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4535186A (en) | 1983-04-19 | 1985-08-13 | American Home Products Corporation | 2-Phenyl-2-(1-hydroxycycloalkyl or 1-hydroxycycloalk-2-enyl)ethylamine derivatives |
| WO1999002522A1 (fr) * | 1997-07-11 | 1999-01-21 | Dainippon Pharmaceutical Co., Ltd. | (r)-n-(1-ethyl-1h-hexahydroazepine-3-yl)-6-methoxy-1h-benzotriazole-5-carbooxamide monofumarate monohydrate et son procede de production |
| HUP0200898A3 (en) * | 1999-04-06 | 2005-09-28 | Sepracor Inc | Derivatives of venlafaxine and methods of preparing and using the same |
| US20020022662A1 (en) | 1999-06-15 | 2002-02-21 | American Home Products Corporation | Enantiomers of O-desmethyl venlafaxine |
| CA2391288A1 (en) * | 1999-11-24 | 2001-05-31 | John Patrick Yardley | Ethers of o-desmethyl venlafaxine |
| US7291646B2 (en) | 1999-11-24 | 2007-11-06 | Wyeth | Ethers of O-desmethyl venlafaxine |
| US6348494B1 (en) * | 2000-11-21 | 2002-02-19 | American Home Products Corporation | Ethers of o-desmethyl venlafaxine |
| EP1334082A4 (en) * | 2000-10-19 | 2006-02-01 | Teva Pharma | CRYSTALLINE BASIS OF VENLAFAXINE AND NEW POLYMORPHS OF VENLAFAXINE HYDROCHLORIDE AND PREPARATION THEREOF |
| WO2002046140A1 (en) * | 2000-12-07 | 2002-06-13 | Dr. Reddy's Laboratories Ltd. | Novel crystalline polymorphic forms of venlafaxine hydrochloride and a process for their preparation |
| EP1864967A1 (en) | 2001-02-12 | 2007-12-12 | Wyeth | Method for preparing O-desmethyl-venlafaxine |
| US20040242594A1 (en) * | 2001-11-17 | 2004-12-02 | Dan Peters | Prodrugs of antidepressants and their use for treating depressions |
| US7030164B2 (en) | 2001-12-05 | 2006-04-18 | Wyeth | Crystalline polymorph of venlafaxine hydrochloride and methods for the preparation thereof |
| AR039166A1 (es) | 2002-03-28 | 2005-02-09 | Synthon Bv | Composiciones de venlafaxina base |
| PL372964A1 (en) * | 2002-04-11 | 2005-08-08 | Teva Pharmaceutical Indudstries, Ltd. | Novel polymorphs and pseudopolymorphs of risedronate sodium |
| AU2005207925B2 (en) * | 2004-01-26 | 2008-09-04 | Merck Sharp & Dohme Corp. | Novel crystalline forms of an inhibitor of 11-beta-hydroxysteroid dehydrogenase Type 1 |
| CN100455560C (zh) * | 2004-06-09 | 2009-01-28 | 中国人民解放军军事医学科学院放射医学研究所 | 含长链脂肪酰基取代的文拉法辛前体药物及其制备方法和用途 |
| CN1955159B (zh) * | 2005-06-17 | 2010-11-24 | 山东绿叶制药有限公司 | 用于阻断5-羟色胺以及去甲基肾上腺素再摄取的化合物,其制备方法及其用途 |
| GT200600397A (es) * | 2005-09-07 | 2007-08-28 | Formulas topicas conteniendo o-desmetil venlafaxina (odv) o sus sales |
-
2011
- 2011-09-28 PT PT118279116T patent/PT2621891T/pt unknown
- 2011-09-28 BR BR112013008664-5A patent/BR112013008664B1/pt active IP Right Grant
- 2011-09-28 DK DK11827911.6T patent/DK2621891T3/da active
- 2011-09-28 AU AU2011307952A patent/AU2011307952B2/en active Active
- 2011-09-28 SG SG2013021472A patent/SG188637A1/en unknown
- 2011-09-28 CN CN201310462622.1A patent/CN103588652B/zh active Active
- 2011-09-28 KR KR1020147007371A patent/KR101477154B1/ko active IP Right Grant
- 2011-09-28 ES ES11827911T patent/ES2769581T3/es active Active
- 2011-09-28 JP JP2013530528A patent/JP2014500234A/ja active Pending
- 2011-09-28 EP EP11827911.6A patent/EP2621891B1/en active Active
- 2011-09-28 BR BR122014004640-5A patent/BR122014004640B1/pt active IP Right Grant
- 2011-09-28 MY MYPI2013001148A patent/MY160607A/en unknown
- 2011-09-28 RU RU2013119806/04A patent/RU2576665C2/ru active
- 2011-09-28 CA CA2812227A patent/CA2812227C/en active Active
- 2011-09-28 CA CA2860747A patent/CA2860747C/en active Active
- 2011-09-28 PL PL11827911T patent/PL2621891T3/pl unknown
- 2011-09-28 BR BR122014004636-7A patent/BR122014004636B1/pt active IP Right Grant
- 2011-09-28 CN CN201310464696.9A patent/CN103588653B/zh active Active
- 2011-09-28 CN CN201180036015.8A patent/CN103025705B/zh active Active
- 2011-09-28 KR KR1020137011253A patent/KR101640808B1/ko active IP Right Grant
- 2011-09-28 WO PCT/CN2011/001637 patent/WO2012041013A1/en active Application Filing
- 2011-09-28 KR KR1020147007372A patent/KR101477155B1/ko active IP Right Grant
- 2011-09-28 CA CA2860748A patent/CA2860748C/en active Active
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2013
- 2013-03-18 US US13/846,773 patent/US8741952B2/en active Active
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2014
- 2014-04-23 US US14/259,964 patent/US9199912B2/en active Active
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2015
- 2015-08-07 JP JP2015156966A patent/JP2015205932A/ja active Pending
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2016
- 2016-06-23 JP JP2016124043A patent/JP2016188233A/ja active Pending
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2017
- 2017-09-08 JP JP2017172806A patent/JP6434591B2/ja active Active
- 2017-09-08 JP JP2017172815A patent/JP2017210494A/ja active Pending
- 2017-12-14 JP JP2017239299A patent/JP6522094B2/ja active Active
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2019
- 2019-07-19 JP JP2019133324A patent/JP6908657B2/ja active Active
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2020
- 2020-02-03 CY CY20201100094T patent/CY1122772T1/el unknown
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