PT2258843T - Vetor de expressão para a produção em massa de uma proteína derivada de um gene estranho utilizando uma célula animal e sua utilização - Google Patents
Vetor de expressão para a produção em massa de uma proteína derivada de um gene estranho utilizando uma célula animal e sua utilização Download PDFInfo
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- PT2258843T PT2258843T PT97150536T PT09715053T PT2258843T PT 2258843 T PT2258843 T PT 2258843T PT 97150536 T PT97150536 T PT 97150536T PT 09715053 T PT09715053 T PT 09715053T PT 2258843 T PT2258843 T PT 2258843T
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- gene
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- expression vector
- foreign gene
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Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y207/00—Transferases transferring phosphorus-containing groups (2.7)
- C12Y207/01—Phosphotransferases with an alcohol group as acceptor (2.7.1)
- C12Y207/01095—Kanamycin kinase (2.7.1.95), i.e. neomycin-kanamycin phosphotransferase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/50—Vector systems having a special element relevant for transcription regulating RNA stability, not being an intron, e.g. poly A signal
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2840/00—Vectors comprising a special translation-regulating system
- C12N2840/10—Vectors comprising a special translation-regulating system regulates levels of translation
- C12N2840/102—Vectors comprising a special translation-regulating system regulates levels of translation inhibiting translation
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
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Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2008046782 | 2008-02-27 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT2258843T true PT2258843T (pt) | 2017-02-07 |
Family
ID=41016160
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT97150536T PT2258843T (pt) | 2008-02-27 | 2009-02-27 | Vetor de expressão para a produção em massa de uma proteína derivada de um gene estranho utilizando uma célula animal e sua utilização |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US8653249B2 (https=) |
| EP (1) | EP2258843B1 (https=) |
| JP (2) | JP5648912B2 (https=) |
| KR (1) | KR101604502B1 (https=) |
| CN (1) | CN102016025B (https=) |
| AU (1) | AU2009218069B2 (https=) |
| CA (1) | CA2716766A1 (https=) |
| DK (1) | DK2258843T3 (https=) |
| ES (1) | ES2616021T3 (https=) |
| PT (1) | PT2258843T (https=) |
| WO (1) | WO2009107775A1 (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK2380979T3 (da) | 2008-12-22 | 2015-06-22 | Univ Hokkaido Nat Univ Corp | Proteinstof med trippelhelixstruktur samt fremgangsmåde til dets fremstilling |
| CN102325881B (zh) * | 2008-12-22 | 2014-08-20 | 国立大学法人北海道大学 | 用于用动物细胞大量生产源自外源基因的蛋白质的表达载体及其应用 |
| WO2016130583A1 (en) * | 2015-02-13 | 2016-08-18 | The Board Of Trustees Of The Leland Stanford Junior University | Non-silencing selectable marker genes and methods of use |
| JP7416355B2 (ja) * | 2021-03-15 | 2024-01-17 | 株式会社ジー・キューブ | 選択マーカー発現カセット |
| CN113969284B (zh) * | 2021-11-23 | 2022-07-12 | 江南大学 | 一种cho细胞基因nw_003614889.1内稳定表达蛋白质的位点及其应用 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU572108B2 (en) | 1983-01-19 | 1988-05-05 | Genentech Inc. | Human tpa production using vectors coding for dhfr protein |
| NZ210501A (en) | 1983-12-13 | 1991-08-27 | Kirin Amgen Inc | Erythropoietin produced by procaryotic or eucaryotic expression of an exogenous dna sequence |
| JP2648860B2 (ja) | 1986-05-08 | 1997-09-03 | イエダ リサーチ アンド デベロップメント コンパニー リミテッド | ヒトインターフエロン−β２Ａ及びヒトインターフエロン−β２Ｂ、該インターフエロンをコードする遺伝子を含むベクター、該インターフエロンを産生するセルライン及び該インターフエロンの医薬品としての用途 |
| DE4142077A1 (de) | 1991-12-19 | 1993-06-24 | Boehringer Mannheim Gmbh | Verfahren zur expression rekombinanter antikoerper |
| JPH0630788A (ja) | 1992-07-16 | 1994-02-08 | Otsuka Pharmaceut Co Ltd | ヒトインターロイキン−１に対する組換え抗体 |
| JP3919830B2 (ja) | 1992-11-28 | 2007-05-30 | 財団法人化学及血清療法研究所 | 抗ネコヘルペスウイルス−１組換え抗体および該抗体をコードする遺伝子断片 |
| JP3582965B2 (ja) | 1996-08-23 | 2004-10-27 | 株式会社イムノ・ジャパン | 哺乳動物細胞用発現ベクター |
| WO2004070030A1 (ja) | 2003-02-03 | 2004-08-19 | Immuno Japan Inc. | 動物細胞用高発現ベクター |
| ES2384391T3 (es) * | 2004-11-08 | 2012-07-04 | Chromagenics B.V. | Selección de células hospedantes que expresan proteína a altos niveles |
| KR101271884B1 (ko) | 2004-11-08 | 2013-06-05 | 크로마제닉스 비.브이. | 고수준으로 단백질을 발현하는 숙주세포의 선택 |
| CN100381573C (zh) * | 2005-04-14 | 2008-04-16 | 北京天广实生物技术有限公司 | 快速构建目标基因高表达的哺乳动物细胞株的体系和方法 |
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- 2009-02-27 CN CN200980114565.XA patent/CN102016025B/zh not_active Expired - Fee Related
- 2009-02-27 ES ES09715053.6T patent/ES2616021T3/es active Active
- 2009-02-27 KR KR1020107021057A patent/KR101604502B1/ko not_active Expired - Fee Related
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- 2009-02-27 WO PCT/JP2009/053682 patent/WO2009107775A1/ja not_active Ceased
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| WO2009107775A1 (ja) | 2009-09-03 |
| CA2716766A1 (en) | 2009-09-03 |
| JPWO2009107775A1 (ja) | 2011-07-07 |
| KR101604502B1 (ko) | 2016-03-17 |
| EP2258843B1 (en) | 2016-11-16 |
| AU2009218069B2 (en) | 2014-05-01 |
| KR20100135755A (ko) | 2010-12-27 |
| AU2009218069A1 (en) | 2009-09-03 |
| EP2258843A4 (en) | 2012-03-14 |
| EP2258843A1 (en) | 2010-12-08 |
| CN102016025B (zh) | 2015-09-16 |
| CN102016025A (zh) | 2011-04-13 |
| DK2258843T3 (en) | 2017-02-13 |
| JP5648912B2 (ja) | 2015-01-07 |
| US20110123993A1 (en) | 2011-05-26 |
| JP6022518B2 (ja) | 2016-11-09 |
| ES2616021T3 (es) | 2017-06-09 |
| HK1155772A1 (en) | 2012-05-25 |
| AU2009218069A2 (en) | 2010-11-04 |
| US8653249B2 (en) | 2014-02-18 |
| JP2015037412A (ja) | 2015-02-26 |
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