PT2225271E - Novos análogos não selectivos de somatostatina - Google Patents
Novos análogos não selectivos de somatostatina Download PDFInfo
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- PT2225271E PT2225271E PT88565197T PT08856519T PT2225271E PT 2225271 E PT2225271 E PT 2225271E PT 88565197 T PT88565197 T PT 88565197T PT 08856519 T PT08856519 T PT 08856519T PT 2225271 E PT2225271 E PT 2225271E
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- pro
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- carbamoyl
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- NHXLMOGPVYXJNR-ATOGVRKGSA-N somatostatin Chemical class C([C@H]1C(=O)N[C@H](C(N[C@@H](CO)C(=O)N[C@@H](CSSC[C@@H](C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC=2C=CC=CC=2)C(=O)N[C@@H](CC=2C=CC=CC=2)C(=O)N[C@@H](CC=2C3=CC=CC=C3NC=2)C(=O)N[C@@H](CCCCN)C(=O)N[C@H](C(=O)N1)[C@@H](C)O)NC(=O)CNC(=O)[C@H](C)N)C(O)=O)=O)[C@H](O)C)C1=CC=CC=C1 NHXLMOGPVYXJNR-ATOGVRKGSA-N 0.000 title abstract description 24
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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Landscapes
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
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| ITMI20072266 ITMI20072266A1 (it) | 2007-12-03 | 2007-12-03 | Nuovi analoghi non selettivi di somatostatina |
| EP07425778A EP2067786A1 (en) | 2007-12-07 | 2007-12-07 | Novel non selective analogs of somatostatin |
Publications (1)
| Publication Number | Publication Date |
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| PT2225271E true PT2225271E (pt) | 2013-09-27 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT88565197T PT2225271E (pt) | 2007-12-03 | 2008-11-24 | Novos análogos não selectivos de somatostatina |
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| Country | Link |
|---|---|
| US (1) | US8937152B2 (enExample) |
| EP (1) | EP2225271B1 (enExample) |
| JP (1) | JP5331817B2 (enExample) |
| KR (1) | KR101500528B1 (enExample) |
| CN (1) | CN101883785B (enExample) |
| BR (1) | BRPI0818978B8 (enExample) |
| CA (1) | CA2702940C (enExample) |
| CY (1) | CY1114490T1 (enExample) |
| DK (1) | DK2225271T3 (enExample) |
| ES (1) | ES2431573T3 (enExample) |
| HR (1) | HRP20130948T1 (enExample) |
| PL (1) | PL2225271T3 (enExample) |
| PT (1) | PT2225271E (enExample) |
| SI (1) | SI2225271T1 (enExample) |
| WO (1) | WO2009071460A2 (enExample) |
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| EP3159352B1 (en) | 2007-03-28 | 2023-08-02 | President and Fellows of Harvard College | Stitched polypeptides |
| ES2431573T3 (es) * | 2007-12-03 | 2013-11-27 | Italfarmaco S.P.A. | Nuevos análogos no selectivos de somatostatina |
| KR102104762B1 (ko) | 2010-08-13 | 2020-04-24 | 에일러론 테라퓨틱스 인코포레이티드 | 펩티도미메틱 거대고리 |
| SG11201400293UA (en) * | 2011-09-04 | 2014-08-28 | Glytech Inc | Glycosylated polypeptide and drug composition containing said polypeptide |
| TW201806968A (zh) | 2011-10-18 | 2018-03-01 | 艾利倫治療公司 | 擬肽巨環化合物 |
| NZ627528A (en) | 2012-02-15 | 2016-05-27 | Aileron Therapeutics Inc | Peptidomimetic macrocycles |
| CA2864120A1 (en) | 2012-02-15 | 2013-08-22 | Aileron Therapeutics, Inc. | Triazole-crosslinked and thioether-crosslinked peptidomimetic macrocycles |
| BR112015009470A2 (pt) | 2012-11-01 | 2019-12-17 | Aileron Therapeutics Inc | aminoácidos dissubstituídos e seus métodos de preparação e uso |
| DK3007704T3 (da) * | 2013-06-13 | 2021-03-29 | Antisense Therapeutics Ltd | Kombinationsterapi til akromegali |
| CN103467575B (zh) * | 2013-08-22 | 2016-03-02 | 深圳翰宇药业股份有限公司 | 一种帕西瑞肽的制备方法 |
| CN103641894B (zh) * | 2013-12-06 | 2015-10-28 | 深圳翰宇药业股份有限公司 | 一种治疗库欣病的多肽药物的制备方法 |
| KR20170058424A (ko) | 2014-09-24 | 2017-05-26 | 에일러론 테라퓨틱스 인코포레이티드 | 펩티드모방 거대고리 및 이의 용도 |
| CN104447962B (zh) * | 2014-12-29 | 2018-07-17 | 成都圣诺生物科技股份有限公司 | 一种合成帕瑞肽的方法 |
| SG11201707750YA (en) | 2015-03-20 | 2017-10-30 | Aileron Therapeutics Inc | Peptidomimetic macrocycles and uses thereof |
| JP7358484B2 (ja) * | 2018-09-25 | 2023-10-10 | アドヴァンスド・アクセラレーター・アプリケーションズ・（イタリー）・エッセエッレエッレ | 併用療法 |
| GB201816637D0 (en) * | 2018-10-12 | 2018-11-28 | Heptares Therapeutics Ltd | Selective somatostatin receptor agonists |
| CN117042789A (zh) * | 2021-03-04 | 2023-11-10 | 斯塔吉特医药有限公司 | 构象受限的生长抑素受体3肽配体及其缀合物和用途 |
| IT202100032615A1 (it) | 2021-12-24 | 2023-06-24 | Italfarmaco Spa | Uso di un agonista della somatostatina nel trattamento di tumori che esprimono SSTR3 |
| CN119708199A (zh) * | 2023-09-27 | 2025-03-28 | 钱杭江医药科技(嘉兴)有限公司 | 生长抑素肽类类似物、螯合物及其应用 |
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| MY147327A (en) * | 1995-06-29 | 2012-11-30 | Novartis Ag | Somatostatin peptides |
| GB0018891D0 (en) | 2000-08-01 | 2000-09-20 | Novartis Ag | Organic compounds |
| US6365380B2 (en) | 2000-02-23 | 2002-04-02 | Pcbu Services, Inc. | Method for stereoselectively inverting a chiral center of a chemical compound using an enzyme and a metal catalyst |
| CA2476324A1 (en) * | 2002-03-12 | 2003-09-25 | The Procter & Gamble Company | Cosmetic composition comprising double coated pigment and a gelling agent |
| GB0206415D0 (en) | 2002-03-19 | 2002-05-01 | Glaxo Group Ltd | Deracemisation of amines |
| GB0300095D0 (en) * | 2003-01-03 | 2003-02-05 | Novartis Ag | Organic compounds |
| PE20050285A1 (es) * | 2003-06-24 | 2005-06-09 | Novartis Ag | Composicion farmaceutica que comprende analogos ciclicos de somatostatina |
| JP2007501775A (ja) * | 2003-08-07 | 2007-02-01 | ノバルティス アクチエンゲゼルシャフト | 免疫抑制剤としてのヒストンデアセチラーゼ阻害剤 |
| GB0318682D0 (en) | 2003-08-08 | 2003-09-10 | Novartis Ag | Organic compounds |
| EP1522311A1 (fr) * | 2003-10-10 | 2005-04-13 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | Utilisation de la somatostine ou d'un de ses analogues pour préparer un médicament destiné à réguler la réserve folliculaire ovarienne chez la femme non ménopausée |
| KR20060118504A (ko) * | 2003-11-25 | 2006-11-23 | 노파르티스 아게 | 소마토스타틴 유사체 치료법의 효능에 대한 바이오마커 |
| ITFI20040057A1 (it) * | 2004-03-10 | 2004-06-10 | Mauro Giuntini | Analoghi della somatostatina |
| GB0428151D0 (en) | 2004-12-22 | 2005-01-26 | Novartis Ag | Organic compounds |
| US7824663B2 (en) * | 2005-03-10 | 2010-11-02 | Kokyu Alcohol Kogyo Co., Ltd. | Lip gloss composition |
| PT1787658E (pt) * | 2005-11-10 | 2012-06-22 | Chemi Spa | Formulações de libertação sustentada de análogos de somatostatina inibidores da hormona do crescimento |
| ES2431573T3 (es) * | 2007-12-03 | 2013-11-27 | Italfarmaco S.P.A. | Nuevos análogos no selectivos de somatostatina |
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| DK2225271T3 (da) | 2013-10-07 |
| JP2011505345A (ja) | 2011-02-24 |
| CA2702940A1 (en) | 2009-06-11 |
| BRPI0818978A2 (pt) | 2016-05-03 |
| JP5331817B2 (ja) | 2013-10-30 |
| EP2225271A2 (en) | 2010-09-08 |
| BRPI0818978B1 (pt) | 2019-09-10 |
| EP2225271B1 (en) | 2013-07-31 |
| US8937152B2 (en) | 2015-01-20 |
| HRP20130948T1 (hr) | 2013-11-08 |
| KR20100103464A (ko) | 2010-09-27 |
| CY1114490T1 (el) | 2016-10-05 |
| CN101883785A (zh) | 2010-11-10 |
| CA2702940C (en) | 2016-09-13 |
| WO2009071460A2 (en) | 2009-06-11 |
| WO2009071460A3 (en) | 2009-12-17 |
| PL2225271T3 (pl) | 2013-12-31 |
| ES2431573T3 (es) | 2013-11-27 |
| SI2225271T1 (sl) | 2013-10-30 |
| US20100323964A1 (en) | 2010-12-23 |
| KR101500528B1 (ko) | 2015-03-09 |
| BRPI0818978B8 (pt) | 2021-05-25 |
| CN101883785B (zh) | 2014-01-15 |
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