PT2155788E - Aglutinantes duplamente específicos, específicos interespécies - Google Patents

Aglutinantes duplamente específicos, específicos interespécies Download PDF

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Publication number
PT2155788E
PT2155788E PT08735000T PT08735000T PT2155788E PT 2155788 E PT2155788 E PT 2155788E PT 08735000 T PT08735000 T PT 08735000T PT 08735000 T PT08735000 T PT 08735000T PT 2155788 E PT2155788 E PT 2155788E
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PT
Portugal
Prior art keywords
seq
rdc
human
binding
region
Prior art date
Application number
PT08735000T
Other languages
English (en)
Portuguese (pt)
Inventor
Peter Kufer
Matthias Klinger
Tobias Raum
Doris Rau
Susanne Mangold
Roman Kischel
Ralf Lutterbuese
Patrick Hoffmann
Original Assignee
Micromet Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Micromet Ag filed Critical Micromet Ag
Publication of PT2155788E publication Critical patent/PT2155788E/pt

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  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PT08735000T 2007-04-03 2008-04-03 Aglutinantes duplamente específicos, específicos interespécies PT2155788E (pt)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
EP07006988 2007-04-03
EP07006990 2007-04-03
US91366807P 2007-04-24 2007-04-24
EP07020646 2007-10-22
EP07020640 2007-10-22
EP07020641 2007-10-22
EP08004741 2008-03-13

Publications (1)

Publication Number Publication Date
PT2155788E true PT2155788E (pt) 2012-09-25

Family

ID=42582614

Family Applications (1)

Application Number Title Priority Date Filing Date
PT08735000T PT2155788E (pt) 2007-04-03 2008-04-03 Aglutinantes duplamente específicos, específicos interespécies

Country Status (8)

Country Link
JP (1) JP2010524435A (enExample)
DK (1) DK2155788T3 (enExample)
ES (1) ES2390243T3 (enExample)
NZ (1) NZ580746A (enExample)
PT (1) PT2155788E (enExample)
RS (1) RS52492B (enExample)
RU (1) RU2535992C2 (enExample)
SI (1) SI2155788T1 (enExample)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4059964A1 (en) * 2007-04-03 2022-09-21 Amgen Research (Munich) GmbH Cross-species-specific binding domain
HRP20120759T1 (hr) * 2007-04-03 2012-10-31 Amgen Research (Munich) Gmbh Bispecifična veziva specifična između vrsta
EP3974453A3 (en) * 2010-11-16 2022-08-03 Amgen Inc. Agents and methods for treating diseases that correlate with bcma expression
CN107903325B (zh) * 2011-05-16 2021-10-29 埃泰美德(香港)有限公司 多特异性fab融合蛋白及其使用方法
SI2714733T1 (sl) * 2011-05-21 2019-06-28 Macrogenics, Inc. CD3-vezavne molekule sposobne vezave na humani ali ne-humani CD3
HUE050156T2 (hu) 2013-12-17 2020-11-30 Genentech Inc Anti-CD3 antitestek és alkalmazási eljárások
JP6738285B2 (ja) * 2014-05-28 2020-08-12 エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト ヒト及びカニクイザルcd3イプシロンに結合する抗体
US10669337B2 (en) * 2014-07-25 2020-06-02 Cytomx Therapeutics, Inc. Bispecific anti-CD3 antibodies, bispecific activatable anti-CD3 antibodies, and methods of using the same
AR101400A1 (es) * 2014-07-31 2016-12-14 Amgen Res Munich Gmbh Constructo de anticuerpo de cadena individual biespecífico con distribución mejorada de tejido
JP2018520642A (ja) * 2015-05-01 2018-08-02 ジェネンテック, インコーポレイテッド マスク抗cd3抗体及びその使用方法
AU2017233121B2 (en) 2016-03-15 2023-12-21 Itabmed (Hk) Limited Multispecific Fab fusion proteins and use thereof
MX2019005438A (es) 2016-11-15 2019-08-16 Genentech Inc Dosificacion para tratamiento con anticuerpos bispecificos anti-cd20 / anti-cd3.
US10426424B2 (en) 2017-11-21 2019-10-01 General Electric Company System and method for generating and performing imaging protocol simulations
CR20200391A (es) 2018-02-08 2020-10-19 Genentech Inc Moléculas biespecíficas de unión al antígeno y métodos de uso
JP7548587B2 (ja) 2018-09-07 2024-09-10 アイタブメッド (エイチケイ) リミテッド 二重特異性抗原結合タンパク質及びその使用
US20230067182A1 (en) * 2019-11-29 2023-03-02 Boe Technology Group Co., Ltd. Data Processing Device and Method, and Computer Readable Storage Medium
US11845799B2 (en) 2019-12-13 2023-12-19 Genentech, Inc. Anti-Ly6G6D antibodies and methods of use
JP2022087602A (ja) * 2020-12-01 2022-06-13 株式会社バイオピーク 組換え大腸菌による有用タンパク質の生産性を向上するための培養方法
WO2022241235A1 (en) 2021-05-14 2022-11-17 Genentech, Inc. Methods for treatment of cd20-positive proliferative disorder with mosunetuzumab and polatuzumab vedotin
CN115932808B (zh) * 2022-11-04 2025-05-27 四川九洲电器集团有限责任公司 一种基于多特征融合的被动声纳智能探测方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2179862C1 (ru) * 2000-12-26 2002-02-27 Общество с ограниченной ответственностью Научно-производственный центр "МедБиоСпектр" Лекарственное средство для предотвращения отторжения трансплантата, моноклональное антитело к cd3-антигену т-лимфоцитов человека, гибридома и способ лечения больных, имеющих реакцию острого отторжения трансплантата после пересадки почки
BRPI0410338A (pt) * 2003-05-31 2006-05-30 Micromet Ag composição farmacêutica compreendendo um constructo de anticorpo biespecìfico para epcam, processo para sua produção, uso de um constructo biespecìfico, kit contendo o mesmo e método para a prevenção, tratamento ou alìvio de uma doença tumoral
US7235641B2 (en) * 2003-12-22 2007-06-26 Micromet Ag Bispecific antibodies
AU2005250499B2 (en) * 2004-06-03 2011-12-08 Novimmune S.A. Anti-CD3 antibodies and methods of use thereof
EP1933868A2 (en) * 2005-09-12 2008-06-25 NovImmune SA Anti-cd3 antibody formulations
EP1940881B1 (en) * 2005-10-11 2016-11-30 Amgen Research (Munich) GmbH Compositions comprising cross-species-specific antibodies and uses thereof

Also Published As

Publication number Publication date
RS52492B (sr) 2013-02-28
JP2010524435A (ja) 2010-07-22
RU2009136913A (ru) 2011-06-20
RU2535992C2 (ru) 2014-12-20
DK2155788T3 (da) 2012-10-08
NZ580746A (en) 2012-05-25
ES2390243T3 (es) 2012-11-07
SI2155788T1 (sl) 2012-11-30

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