ES2390243T3 - Agentes de unión biespecíficos específicos de especies cruzadas - Google Patents

Agentes de unión biespecíficos específicos de especies cruzadas Download PDF

Info

Publication number
ES2390243T3
ES2390243T3 ES08735000T ES08735000T ES2390243T3 ES 2390243 T3 ES2390243 T3 ES 2390243T3 ES 08735000 T ES08735000 T ES 08735000T ES 08735000 T ES08735000 T ES 08735000T ES 2390243 T3 ES2390243 T3 ES 2390243T3
Authority
ES
Spain
Prior art keywords
seq
cdr
represented
human
binding
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES08735000T
Other languages
English (en)
Spanish (es)
Inventor
Matthias Klinger
Tobias Raum
Doris Rau
Susanne Mangold
Roman Kischel
Ralf Lutterbüse
Patrick Hoffmann
Peter Kufer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Amgen Research Munich GmbH
Original Assignee
Micromet GmbH
Amgen Research Munich GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Micromet GmbH, Amgen Research Munich GmbH filed Critical Micromet GmbH
Priority claimed from PCT/EP2008/002663 external-priority patent/WO2008119566A2/en
Application granted granted Critical
Publication of ES2390243T3 publication Critical patent/ES2390243T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Landscapes

  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
ES08735000T 2007-04-03 2008-04-03 Agentes de unión biespecíficos específicos de especies cruzadas Active ES2390243T3 (es)

Applications Claiming Priority (15)

Application Number Priority Date Filing Date Title
EP07006988 2007-04-03
EP07006988 2007-04-03
EP07006990 2007-04-03
EP07006990 2007-04-03
US91366807P 2007-04-24 2007-04-24
US913668P 2007-04-24
EP07020646 2007-10-22
EP07020640 2007-10-22
EP07020640 2007-10-22
EP07020646 2007-10-22
EP07020641 2007-10-22
EP07020641 2007-10-22
EP08004741 2008-03-13
EP08004741 2008-03-13
PCT/EP2008/002663 WO2008119566A2 (en) 2007-04-03 2008-04-03 Cross-species-specific bispecific binders

Publications (1)

Publication Number Publication Date
ES2390243T3 true ES2390243T3 (es) 2012-11-07

Family

ID=42582614

Family Applications (1)

Application Number Title Priority Date Filing Date
ES08735000T Active ES2390243T3 (es) 2007-04-03 2008-04-03 Agentes de unión biespecíficos específicos de especies cruzadas

Country Status (8)

Country Link
JP (1) JP2010524435A (enExample)
DK (1) DK2155788T3 (enExample)
ES (1) ES2390243T3 (enExample)
NZ (1) NZ580746A (enExample)
PT (1) PT2155788E (enExample)
RS (1) RS52492B (enExample)
RU (1) RU2535992C2 (enExample)
SI (1) SI2155788T1 (enExample)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100150918A1 (en) * 2007-04-03 2010-06-17 Micromet Ag Cross-species-specific binding domain
WO2008119566A2 (en) * 2007-04-03 2008-10-09 Micromet Ag Cross-species-specific bispecific binders
US20130273055A1 (en) * 2010-11-16 2013-10-17 Eric Borges Agents and methods for treating diseases that correlate with bcma expression
US8846042B2 (en) * 2011-05-16 2014-09-30 Fabion Pharmaceuticals, Inc. Multi-specific FAB fusion proteins and methods of use
UA115402C2 (uk) * 2011-05-21 2017-10-25 Макродженікс, Інк. Cd3-зв'язувальна молекула, здатна до зв'язування з cd3 людини і cd3, що не є людським
JP6449295B2 (ja) 2013-12-17 2019-01-09 ジェネンテック, インコーポレイテッド 抗cd3抗体および使用方法
KR20170003591A (ko) * 2014-05-28 2017-01-09 에프. 호프만-라 로슈 아게 인간 및 사이노몰구스 cd3 엡실론에 결합하는 항체
CN107108738A (zh) * 2014-07-25 2017-08-29 西托姆克斯治疗公司 抗cd3抗体、可活化抗cd3抗体、多特异性抗cd3抗体、多特异性可活化抗cd3抗体及其使用方法
US20170275373A1 (en) * 2014-07-31 2017-09-28 Amgen Research (Munich) Gmbh Bispecific single chain antibody construct with enhanced tissue distribution
HK1252158A1 (zh) * 2015-05-01 2019-05-17 Genentech, Inc. 掩蔽抗cd3抗体和使用方法
EP3430058A4 (en) 2016-03-15 2019-10-23 Generon (Shanghai) Corporation Ltd. MULTISPECIFIC FAB FUSION PROTEINS AND USES THEREOF
WO2018093821A1 (en) 2016-11-15 2018-05-24 Genentech, Inc. Dosing for treatment with anti-cd20/anti-cd3 bispecific antibodies
US10426424B2 (en) 2017-11-21 2019-10-01 General Electric Company System and method for generating and performing imaging protocol simulations
MA51793A (fr) 2018-02-08 2020-12-16 Hoffmann La Roche Molécules bispécifiques de liaison à l'antigène et procédés d'utilisation
EP3847196A4 (en) 2018-09-07 2023-01-04 ITabMed (HK) Limited BISPECIFIC ANTIGEN BINDING PROTEINS AND USES THEREOF
US20230067182A1 (en) * 2019-11-29 2023-03-02 Boe Technology Group Co., Ltd. Data Processing Device and Method, and Computer Readable Storage Medium
TWI897903B (zh) 2019-12-13 2025-09-21 美商建南德克公司 抗ly6g6d抗體及其使用方法
JP2022087602A (ja) * 2020-12-01 2022-06-13 株式会社バイオピーク 組換え大腸菌による有用タンパク質の生産性を向上するための培養方法
KR20240007171A (ko) 2021-05-14 2024-01-16 제넨테크, 인크. 모수네투주맙 및 폴라투주맙 베도틴을 이용한 cd20 양성 증식성 장애의 치료 방법
CN115932808B (zh) * 2022-11-04 2025-05-27 四川九洲电器集团有限责任公司 一种基于多特征融合的被动声纳智能探测方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2179862C1 (ru) * 2000-12-26 2002-02-27 Общество с ограниченной ответственностью Научно-производственный центр "МедБиоСпектр" Лекарственное средство для предотвращения отторжения трансплантата, моноклональное антитело к cd3-антигену т-лимфоцитов человека, гибридома и способ лечения больных, имеющих реакцию острого отторжения трансплантата после пересадки почки
CA2522894C (en) * 2003-05-31 2013-06-25 Micromet Ag Pharmaceutical composition comprising a bispecific antibody specific for epcam
US7235641B2 (en) * 2003-12-22 2007-06-26 Micromet Ag Bispecific antibodies
US7728114B2 (en) * 2004-06-03 2010-06-01 Novimmune S.A. Anti-CD3 antibodies and methods of use thereof
US20070065437A1 (en) * 2005-09-12 2007-03-22 Greg Elson Anti-CD3 antibody formulations
CA2625440C (en) * 2005-10-11 2023-06-13 Micromet Ag Compositions comprising cross-species-specific antibodies and uses thereof

Also Published As

Publication number Publication date
DK2155788T3 (da) 2012-10-08
RU2009136913A (ru) 2011-06-20
RU2535992C2 (ru) 2014-12-20
JP2010524435A (ja) 2010-07-22
SI2155788T1 (sl) 2012-11-30
NZ580746A (en) 2012-05-25
PT2155788E (pt) 2012-09-25
RS52492B (sr) 2013-02-28

Similar Documents

Publication Publication Date Title
ES2390243T3 (es) Agentes de unión biespecíficos específicos de especies cruzadas
US11987633B2 (en) Cross-species-specific single domain bispecific single chain antibody
US20200095319A1 (en) Cross-species-specific bispecific binders
ES2432792T5 (es) Dominio de unión a CD3-épsilon específico de especies cruzadas
CA2683370C (en) Cross-species-specific binding domain
US20230357444A1 (en) Cross-species-specific binding domain
HK40072623A (en) Cross-species-specific binding domain
HK1141299B (en) Cross-species-specific bispecific binders
BRPI0809594B1 (pt) Polipeptídeo, sequência de ácido nucléico, vetor, processo para a produção de um polipeptídeo, composição farmacêutica, kit e uso de um fragmento n-terminal do domínio extracelular de cd3? de máximo de 27 aminoácidos
HK1178542B (en) Cross-species-specific binding domain
HK1141300B (en) Cross-species-specific cd3-epsilon binding domain