RS52492B - Molekuli koji se interspecijski specifično bispecifično vezuju - Google Patents

Molekuli koji se interspecijski specifično bispecifično vezuju

Info

Publication number
RS52492B
RS52492B RS20120412A RSP20120412A RS52492B RS 52492 B RS52492 B RS 52492B RS 20120412 A RS20120412 A RS 20120412A RS P20120412 A RSP20120412 A RS P20120412A RS 52492 B RS52492 B RS 52492B
Authority
RS
Serbia
Prior art keywords
seq
cdr
human
binding
region
Prior art date
Application number
RS20120412A
Other languages
English (en)
Serbian (sr)
Inventor
Matthias Klinger
Tobias Raum
Doris Rau
Roman Kischel
Ralf LUTTERBĂśSE
Patrick Hoffmann
Peter Kufer
Susanne Mangold
Original Assignee
Amgen Research (Munich) Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amgen Research (Munich) Gmbh filed Critical Amgen Research (Munich) Gmbh
Priority claimed from PCT/EP2008/002663 external-priority patent/WO2008119566A2/en
Publication of RS52492B publication Critical patent/RS52492B/sr

Links

Landscapes

  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
RS20120412A 2007-04-03 2008-04-03 Molekuli koji se interspecijski specifično bispecifično vezuju RS52492B (sr)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
EP07006988 2007-04-03
EP07006990 2007-04-03
US91366807P 2007-04-24 2007-04-24
EP07020640 2007-10-22
EP07020646 2007-10-22
EP07020641 2007-10-22
EP08004741 2008-03-13
PCT/EP2008/002663 WO2008119566A2 (en) 2007-04-03 2008-04-03 Cross-species-specific bispecific binders

Publications (1)

Publication Number Publication Date
RS52492B true RS52492B (sr) 2013-02-28

Family

ID=42582614

Family Applications (1)

Application Number Title Priority Date Filing Date
RS20120412A RS52492B (sr) 2007-04-03 2008-04-03 Molekuli koji se interspecijski specifično bispecifično vezuju

Country Status (8)

Country Link
JP (1) JP2010524435A (enExample)
DK (1) DK2155788T3 (enExample)
ES (1) ES2390243T3 (enExample)
NZ (1) NZ580746A (enExample)
PT (1) PT2155788E (enExample)
RS (1) RS52492B (enExample)
RU (1) RU2535992C2 (enExample)
SI (1) SI2155788T1 (enExample)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109456410B (zh) * 2007-04-03 2022-01-28 安进研发（慕尼黑）股份有限公司 跨物种特异性CD3-ε结合结构域
US20100183615A1 (en) * 2007-04-03 2010-07-22 Micromet Ag Cross-species-specific bispecific binders
US20130273055A1 (en) * 2010-11-16 2013-10-17 Eric Borges Agents and methods for treating diseases that correlate with bcma expression
WO2012158818A2 (en) 2011-05-16 2012-11-22 Fabion Pharmaceuticals, Inc. Multi-specific fab fusion proteins and methods of use
US9587021B2 (en) * 2011-05-21 2017-03-07 Macrogenics, Inc. CD3-binding molecules capable of binding to human and non-human CD3
MX379030B (es) 2013-12-17 2025-03-10 Genentech Inc Anticuerpos anti-cd3 y metodos de uso
RU2016151235A (ru) * 2014-05-28 2018-06-28 Ф. Хоффманн-Ля Рош Аг Антитела, связывающиеся с cd3 эпсилон человека и обезьян циномолгус
WO2016014974A2 (en) * 2014-07-25 2016-01-28 Cytomx Therapeutics, Inc. Anti-cd3 antibodies, activatable anti-cd3 antibodies, multispecific anti-cd3 antibodies, multispecific activatable anti-cd3 antibodies, and methods of using the same
WO2016016415A1 (en) * 2014-07-31 2016-02-04 Amgen Research (Munich) Gmbh Bispecific single chain antibody construct with enhanced tissue distribution
HK1250997A1 (zh) * 2015-05-01 2019-01-18 基因泰克公司 掩蔽抗cd3抗体和使用方法
JP7034489B2 (ja) 2016-03-15 2022-03-14 アイタブメッド （エイチケイ） リミテッド 多重特異性Ｆａｂ融合タンパクおよびその使用
KR20190074300A (ko) 2016-11-15 2019-06-27 제넨테크, 인크. 항-cd20/항-cd3 이중특이적 항체에 의한 치료를 위한 투약
US10426424B2 (en) 2017-11-21 2019-10-01 General Electric Company System and method for generating and performing imaging protocol simulations
AR115360A1 (es) 2018-02-08 2021-01-13 Genentech Inc Moléculas de unión al antígeno y métodos de uso
US12460000B2 (en) 2018-09-07 2025-11-04 Itabmed (Hk) Limited Anti-CD19 and anti-CD3 bispecific antigen binding proteins and uses thereof
WO2020132810A1 (en) 2018-12-24 2020-07-02 Generon (Shanghai) Corporation Ltd. Multispecific antigen binding proteins capable of binding cd19 and cd3, and use thereof
US20230067182A1 (en) * 2019-11-29 2023-03-02 Boe Technology Group Co., Ltd. Data Processing Device and Method, and Computer Readable Storage Medium
BR112022011357A2 (pt) 2019-12-13 2022-08-23 Genentech Inc Anticorpos isolado, um ou mais ácidos nucleicos isolados, um ou mais vetores, uma ou mais células hospedeiras, composição, kit, uso do anticorpo, métodos para produzir o anticorpo e método para tratar ou retardar a progressão de um câncer ly6g6d positivo
JP2022087602A (ja) * 2020-12-01 2022-06-13 株式会社バイオピーク 組換え大腸菌による有用タンパク質の生産性を向上するための培養方法
KR20240007171A (ko) 2021-05-14 2024-01-16 제넨테크, 인크. 모수네투주맙 및 폴라투주맙 베도틴을 이용한 cd20 양성 증식성 장애의 치료 방법
CN115932808B (zh) * 2022-11-04 2025-05-27 四川九洲电器集团有限责任公司 一种基于多特征融合的被动声纳智能探测方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2179862C1 (ru) * 2000-12-26 2002-02-27 Общество с ограниченной ответственностью Научно-производственный центр "МедБиоСпектр" Лекарственное средство для предотвращения отторжения трансплантата, моноклональное антитело к cd3-антигену т-лимфоцитов человека, гибридома и способ лечения больных, имеющих реакцию острого отторжения трансплантата после пересадки почки
EP1629013B1 (en) * 2003-05-31 2018-01-24 Amgen Research (Munich) GmbH Pharmaceutical composition comprising a bispecific antibody specific for epcam
US7235641B2 (en) * 2003-12-22 2007-06-26 Micromet Ag Bispecific antibodies
MXPA06014075A (es) * 2004-06-03 2007-03-15 Novimmune Sa Anticuerpos anti-cd3 y metodos de uso de los mismos.
AR057807A1 (es) * 2005-09-12 2007-12-19 Novimmune Sa Formulaciones de anticuerpo anti-cd3
JP5686953B2 (ja) * 2005-10-11 2015-03-18 アムゲン リサーチ （ミュンヘン） ゲーエムベーハー 交差種特異的（ｃｒｏｓｓ−ｓｐｅｃｉｅｓ−ｓｐｅｃｉｆｉｃ）抗体を含む組成物および該組成物の使用

Also Published As

Publication number Publication date
SI2155788T1 (sl) 2012-11-30
JP2010524435A (ja) 2010-07-22
RU2009136913A (ru) 2011-06-20
RU2535992C2 (ru) 2014-12-20
NZ580746A (en) 2012-05-25
ES2390243T3 (es) 2012-11-07
DK2155788T3 (da) 2012-10-08
PT2155788E (pt) 2012-09-25

Similar Documents

Publication Publication Date Title
US20200095319A1 (en) Cross-species-specific bispecific binders
CN103694350B (zh) 跨物种特异性CD3-ε结合结构域
RU2535992C2 (ru) Биспецифические связывающие агенты с межвидовой специфичностью
CA2683370C (en) Cross-species-specific binding domain
RS54900B1 (sr) Interspecijski specifično psmaxcd3 bispecifično jednolančano antitelo
WO2010037838A2 (en) Cross-species-specific single domain bispecific single chain antibody
US20230357444A1 (en) Cross-species-specific binding domain
HK40072623A (en) Cross-species-specific binding domain
HK1141299B (en) Cross-species-specific bispecific binders
HK1178542B (en) Cross-species-specific binding domain