PT2061512T - Conjugados de péptidos com rgd e fotossensibilizantes de (bacterio)clorofila e as suas utilizações - Google Patents
Conjugados de péptidos com rgd e fotossensibilizantes de (bacterio)clorofila e as suas utilizaçõesInfo
- Publication number
- PT2061512T PT2061512T PT78055159T PT07805515T PT2061512T PT 2061512 T PT2061512 T PT 2061512T PT 78055159 T PT78055159 T PT 78055159T PT 07805515 T PT07805515 T PT 07805515T PT 2061512 T PT2061512 T PT 2061512T
- Authority
- PT
- Portugal
- Prior art keywords
- bacterio
- photosensitizers
- rgd
- chlorophyll
- conjugates
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/12—Cyclic peptides with only normal peptide bonds in the ring
- C07K5/123—Tripeptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
- A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
- A61K41/0071—PDT with porphyrins having exactly 20 ring atoms, i.e. based on the non-expanded tetrapyrrolic ring system, e.g. bacteriochlorin, chlorin-e6, or phthalocyanines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0815—Tripeptides with the first amino acid being basic
- C07K5/0817—Tripeptides with the first amino acid being basic the first amino acid being Arg
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/12—Cyclic peptides with only normal peptide bonds in the ring
- C07K5/126—Tetrapeptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/64—Cyclic peptides containing only normal peptide links
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Ophthalmology & Optometry (AREA)
- Cardiology (AREA)
- Child & Adolescent Psychology (AREA)
- Oncology (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Heart & Thoracic Surgery (AREA)
- Diabetes (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicinal Preparation (AREA)
- Magnetic Resonance Imaging Apparatus (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US83940906P | 2006-08-23 | 2006-08-23 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT2061512T true PT2061512T (pt) | 2020-01-14 |
Family
ID=38896083
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT78055159T PT2061512T (pt) | 2006-08-23 | 2007-08-23 | Conjugados de péptidos com rgd e fotossensibilizantes de (bacterio)clorofila e as suas utilizações |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20080138278A1 (https=) |
| EP (1) | EP2061512B1 (https=) |
| JP (3) | JP2010502574A (https=) |
| AU (1) | AU2007287205B8 (https=) |
| CA (1) | CA2661319C (https=) |
| DK (1) | DK2061512T3 (https=) |
| ES (1) | ES2763237T3 (https=) |
| HU (1) | HUE047789T2 (https=) |
| IL (1) | IL197195A (https=) |
| PT (1) | PT2061512T (https=) |
| RU (1) | RU2450018C2 (https=) |
| WO (1) | WO2008023378A1 (https=) |
Families Citing this family (47)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6850788B2 (en) | 2002-03-25 | 2005-02-01 | Masimo Corporation | Physiological measurement communications adapter |
| US9161696B2 (en) | 2006-09-22 | 2015-10-20 | Masimo Corporation | Modular patient monitor |
| US8840549B2 (en) | 2006-09-22 | 2014-09-23 | Masimo Corporation | Modular patient monitor |
| JP2010539163A (ja) * | 2007-09-14 | 2010-12-16 | ヘルス リサーチ インコーポレイテッド | 腫瘍イメージング及び治療用のマルチモーダル剤 |
| AU2009219682B2 (en) | 2008-02-27 | 2015-06-18 | Yeda Research & Development Co. Ltd | RGD-(bacterio)chlorophyll conjugates for photodynamic therapy and imaging of necrotic tumors |
| LT5567B (lt) | 2008-08-06 | 2009-04-27 | Vilniaus Universitetas | Maisto ir su maistu susietų paviršių nukenksminimo būdas |
| US8673270B2 (en) * | 2008-10-23 | 2014-03-18 | Steba Biotech S.A. | RGD-containing peptidomimetics and uses thereof |
| US8263133B2 (en) * | 2009-02-18 | 2012-09-11 | The Regents Of The University Of California | Multivalent clustering targeting strategy for drug carriers |
| US9153112B1 (en) | 2009-12-21 | 2015-10-06 | Masimo Corporation | Modular patient monitor |
| PL219569B1 (pl) | 2010-02-19 | 2015-05-29 | Peptaderm Spółka Z Ograniczoną Odpowiedzialnością | Cykliczne tetrapeptydy i ich zastosowanie |
| EP2714694A4 (en) * | 2011-05-31 | 2014-11-05 | Univ North Carolina State | BAKTERIOCHLORIMIDE |
| RU2632439C2 (ru) * | 2011-08-23 | 2017-10-04 | Йеда Рисерч Энд Дивелопмент Ко., Лтд. | Фотосенсибилизаторы на основе (бактерио)хлорофилла для лечения глазных заболеваний и расстройств |
| JP6104920B2 (ja) | 2011-10-13 | 2017-03-29 | マシモ・コーポレイション | 医療用監視ハブ |
| US9943269B2 (en) | 2011-10-13 | 2018-04-17 | Masimo Corporation | System for displaying medical monitoring data |
| US10149616B2 (en) | 2012-02-09 | 2018-12-11 | Masimo Corporation | Wireless patient monitoring device |
| US10307111B2 (en) | 2012-02-09 | 2019-06-04 | Masimo Corporation | Patient position detection system |
| KR101385196B1 (ko) | 2012-05-17 | 2014-04-14 | 주식회사 유니크메디케어 | 광 조사를 이용한 광감각제―펩타이드를 유효성분으로 포함하는 발모 개선 또는 촉진용 조성물 및 이를 이용한 방법 |
| CN103665107B (zh) * | 2012-09-05 | 2017-07-14 | 上海晟顺生物科技有限公司 | 同时具溶血栓、清除自由基和血栓靶向功能的新颖化合物及其制备方法和用途 |
| US9749232B2 (en) | 2012-09-20 | 2017-08-29 | Masimo Corporation | Intelligent medical network edge router |
| RU2548675C9 (ru) * | 2013-05-29 | 2015-11-10 | Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Московский государственный университет тонких химических технологий имени М.В. Ломоносова" (МИТХТ им. М.В. Ломоносова) | Аминоамиды в ряду бактериохлорофилла a, обладающие фотодинамической активностью, и способ их получения |
| JP6263716B2 (ja) * | 2013-07-31 | 2018-01-24 | 国立大学法人 筑波大学 | 悪性腫瘍のｐｅｔ診断用トレーサー |
| US10832818B2 (en) | 2013-10-11 | 2020-11-10 | Masimo Corporation | Alarm notification system |
| US9522925B2 (en) * | 2014-11-09 | 2016-12-20 | Hong Kong Baptist University | Selective cancer tracking eradicator and the uses thereof |
| AU2016300208B2 (en) * | 2015-07-29 | 2019-08-08 | Novartis Ag | Combined use of anti PD-1 and anti M-CSF antibodies in the treatment of cancer |
| SG10201506686WA (en) * | 2015-08-24 | 2017-03-30 | Agency Science Tech & Res | Conjugates |
| EP3344123B1 (en) | 2015-08-31 | 2022-10-26 | Masimo Corporation | Wireless patient monitoring methods |
| CN105837666A (zh) * | 2015-12-30 | 2016-08-10 | 田梗 | 一种用于诊断糖尿病性视网膜病的蛋白质 |
| KR20190008206A (ko) * | 2016-04-10 | 2019-01-23 | 예다 리서치 앤드 디벨럽먼트 캄파니 리미티드 | 암 치료를 위한 병용요법 |
| US10617302B2 (en) | 2016-07-07 | 2020-04-14 | Masimo Corporation | Wearable pulse oximeter and respiration monitor |
| CN107759804B (zh) * | 2016-08-19 | 2019-12-03 | 四川大学 | 可定点结合含组氨酸标签蛋白的明胶衍生材料及其制备方法 |
| EP3525661B1 (en) | 2016-10-13 | 2025-07-23 | Masimo Corporation | Systems and methods for patient fall detection |
| US10933134B2 (en) | 2017-03-16 | 2021-03-02 | Memorial Sloan Kettering Cancer Center | Combination therapies for treatment of cancer |
| WO2019204368A1 (en) | 2018-04-19 | 2019-10-24 | Masimo Corporation | Mobile patient alarm display |
| AU2019357721B2 (en) | 2018-10-12 | 2025-05-08 | Masimo Corporation | System for transmission of sensor data using dual communication protocol |
| US12495968B2 (en) | 2018-10-12 | 2025-12-16 | Masimo Corporation | System for transmission of sensor data using dual communication protocol |
| CN110215438B (zh) * | 2019-07-15 | 2021-06-29 | 中国医学科学院生物医学工程研究所 | 双载蒽环类药物及光敏剂介孔硅纳米粒的制备方法与应用 |
| WO2021188999A2 (en) | 2020-03-20 | 2021-09-23 | Masimo Corporation | Health monitoring system for limiting the spread of an infection in an organization |
| USD980091S1 (en) | 2020-07-27 | 2023-03-07 | Masimo Corporation | Wearable temperature measurement device |
| USD974193S1 (en) | 2020-07-27 | 2023-01-03 | Masimo Corporation | Wearable temperature measurement device |
| USD1072837S1 (en) | 2020-10-27 | 2025-04-29 | Masimo Corporation | Display screen or portion thereof with graphical user interface |
| USD1000975S1 (en) | 2021-09-22 | 2023-10-10 | Masimo Corporation | Wearable temperature measurement device |
| EP4404831A1 (en) | 2021-09-22 | 2024-07-31 | Masimo Corporation | Wearable device for noninvasive body temperature measurement |
| CN115960160B (zh) * | 2021-10-12 | 2024-07-16 | 南京大学 | 活细胞膜整合素αvβ3聚糖的原位糖链延长方法 |
| EP4432919A1 (en) | 2022-01-05 | 2024-09-25 | Masimo Corporation | Wrist and finger worn pulse oximetry system |
| USD1048908S1 (en) | 2022-10-04 | 2024-10-29 | Masimo Corporation | Wearable sensor |
| CN117045787B (zh) * | 2023-09-27 | 2025-09-02 | 中国人民解放军陆军军医大学第二附属医院 | 一种自组装型纳米光敏剂及制备方法和应用 |
| WO2025105486A1 (ja) * | 2023-11-17 | 2025-05-22 | 第一三共株式会社 | 抗体－光感受性物質コンジュゲート |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE158589T1 (de) * | 1991-11-22 | 1997-10-15 | Yeda Res & Dev | Nicht-peptidische surrogate der arg-gly-asp sequenz und entsprechende pharmazeutische zusammensetzungen |
| IL102645A (en) * | 1992-07-26 | 1998-02-22 | Yeda Res & Dev | Chlorophyll and bacteriochlorophyll derivatives, their preparation and pharmaceutical compositions comprising them |
| IL116126A0 (en) * | 1995-11-24 | 1996-01-31 | Yeda Res & Dev | Process for the preparation of bacteriochlorophyllis some novel compounds of this type and pharmaceutical compositions comprising them |
| US20030004334A1 (en) * | 2001-06-01 | 2003-01-02 | Ceramoptec Industries, Inc. | Water-soluble porphyrin derivatives and methods of their preparation |
-
2007
- 2007-08-23 PT PT78055159T patent/PT2061512T/pt unknown
- 2007-08-23 CA CA2661319A patent/CA2661319C/en not_active Expired - Fee Related
- 2007-08-23 ES ES07805515T patent/ES2763237T3/es active Active
- 2007-08-23 RU RU2009110226/04A patent/RU2450018C2/ru not_active IP Right Cessation
- 2007-08-23 EP EP07805515.9A patent/EP2061512B1/en not_active Not-in-force
- 2007-08-23 JP JP2009525172A patent/JP2010502574A/ja active Pending
- 2007-08-23 US US11/843,996 patent/US20080138278A1/en not_active Abandoned
- 2007-08-23 DK DK07805515.9T patent/DK2061512T3/da active
- 2007-08-23 HU HUE07805515A patent/HUE047789T2/hu unknown
- 2007-08-23 WO PCT/IL2007/001055 patent/WO2008023378A1/en not_active Ceased
- 2007-08-23 AU AU2007287205A patent/AU2007287205B8/en not_active Ceased
-
2009
- 2009-02-23 IL IL197195A patent/IL197195A/en active IP Right Grant
-
2013
- 2013-06-05 JP JP2013118542A patent/JP6177013B2/ja not_active Expired - Fee Related
-
2016
- 2016-07-22 JP JP2016144093A patent/JP2017039700A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JP2017039700A (ja) | 2017-02-23 |
| JP2013231039A (ja) | 2013-11-14 |
| EP2061512A1 (en) | 2009-05-27 |
| CA2661319C (en) | 2015-12-01 |
| HUE047789T2 (hu) | 2020-05-28 |
| ES2763237T3 (es) | 2020-05-27 |
| AU2007287205B2 (en) | 2013-04-18 |
| AU2007287205B8 (en) | 2013-08-15 |
| JP2010502574A (ja) | 2010-01-28 |
| WO2008023378A1 (en) | 2008-02-28 |
| WO2008023378A9 (en) | 2008-04-10 |
| DK2061512T3 (da) | 2020-01-20 |
| RU2450018C2 (ru) | 2012-05-10 |
| EP2061512B1 (en) | 2019-10-02 |
| CA2661319A1 (en) | 2008-02-28 |
| AU2007287205A1 (en) | 2008-02-28 |
| US20080138278A1 (en) | 2008-06-12 |
| RU2009110226A (ru) | 2010-09-27 |
| JP6177013B2 (ja) | 2017-08-09 |
| IL197195A (en) | 2015-10-29 |
| IL197195A0 (en) | 2009-12-24 |
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