PT2035432E - 2-(amino substituído)-benzotiazole-sulfonamidas como inibidores de protease de hiv - Google Patents

2-(amino substituído)-benzotiazole-sulfonamidas como inibidores de protease de hiv Download PDF

Info

Publication number
PT2035432E
PT2035432E PT07765554T PT07765554T PT2035432E PT 2035432 E PT2035432 E PT 2035432E PT 07765554 T PT07765554 T PT 07765554T PT 07765554 T PT07765554 T PT 07765554T PT 2035432 E PT2035432 E PT 2035432E
Authority
PT
Portugal
Prior art keywords
compound
alkyl
compounds
formula
hiv
Prior art date
Application number
PT07765554T
Other languages
English (en)
Portuguese (pt)
Inventor
Herman De Kock
Tim Hugo Maria Jonckers
Paul Jozef Gabriel Maria Boonants
Stefaan Julien Last
Inge Dierynck
Judith Eva Baumeister
Gerben Albert Eleutherius Van T Klooster
Original Assignee
Tibotec Pharm Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tibotec Pharm Ltd filed Critical Tibotec Pharm Ltd
Publication of PT2035432E publication Critical patent/PT2035432E/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D493/00Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
PT07765554T 2006-06-23 2007-06-22 2-(amino substituído)-benzotiazole-sulfonamidas como inibidores de protease de hiv PT2035432E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP06116003 2006-06-23

Publications (1)

Publication Number Publication Date
PT2035432E true PT2035432E (pt) 2012-04-24

Family

ID=37596252

Family Applications (1)

Application Number Title Priority Date Filing Date
PT07765554T PT2035432E (pt) 2006-06-23 2007-06-22 2-(amino substituído)-benzotiazole-sulfonamidas como inibidores de protease de hiv

Country Status (31)

Country Link
US (1) US8202887B2 (US20060241273A1-20061026-C00026.png)
EP (1) EP2035432B1 (US20060241273A1-20061026-C00026.png)
JP (1) JP5232776B2 (US20060241273A1-20061026-C00026.png)
KR (1) KR101419320B1 (US20060241273A1-20061026-C00026.png)
CN (1) CN101479275B (US20060241273A1-20061026-C00026.png)
AP (1) AP2069A (US20060241273A1-20061026-C00026.png)
AR (1) AR061619A1 (US20060241273A1-20061026-C00026.png)
AT (1) ATE544769T1 (US20060241273A1-20061026-C00026.png)
AU (1) AU2007262943B2 (US20060241273A1-20061026-C00026.png)
BR (1) BRPI0713487B1 (US20060241273A1-20061026-C00026.png)
CA (1) CA2653233C (US20060241273A1-20061026-C00026.png)
CL (1) CL2007001826A1 (US20060241273A1-20061026-C00026.png)
CY (1) CY1112971T1 (US20060241273A1-20061026-C00026.png)
DK (1) DK2035432T3 (US20060241273A1-20061026-C00026.png)
EA (1) EA016387B1 (US20060241273A1-20061026-C00026.png)
ES (1) ES2381129T3 (US20060241273A1-20061026-C00026.png)
HK (1) HK1125633A1 (US20060241273A1-20061026-C00026.png)
IL (1) IL195381A (US20060241273A1-20061026-C00026.png)
JO (1) JO2841B1 (US20060241273A1-20061026-C00026.png)
MX (1) MX2009000160A (US20060241273A1-20061026-C00026.png)
MY (1) MY146805A (US20060241273A1-20061026-C00026.png)
NZ (1) NZ573286A (US20060241273A1-20061026-C00026.png)
PE (1) PE20080342A1 (US20060241273A1-20061026-C00026.png)
PL (1) PL2035432T3 (US20060241273A1-20061026-C00026.png)
PT (1) PT2035432E (US20060241273A1-20061026-C00026.png)
SI (1) SI2035432T1 (US20060241273A1-20061026-C00026.png)
TW (1) TWI415851B (US20060241273A1-20061026-C00026.png)
UA (1) UA96445C2 (US20060241273A1-20061026-C00026.png)
UY (1) UY30416A1 (US20060241273A1-20061026-C00026.png)
WO (1) WO2007147884A1 (US20060241273A1-20061026-C00026.png)
ZA (1) ZA200810350B (US20060241273A1-20061026-C00026.png)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JO3090B1 (ar) * 2009-12-11 2017-03-15 Janssen Sciences Ireland Uc 5- امينو-4- هيدروكسي-بنتويل اميدات
MX2012015293A (es) 2010-07-02 2013-05-30 Gilead Sciences Inc Derivados de acido 2-quinolinil-acetico como compuestos antivirales.
EP2588450B1 (en) 2010-07-02 2017-05-24 Gilead Sciences, Inc. Napht-2-ylacetic acid derivatives to treat aids
US9024038B2 (en) * 2010-12-27 2015-05-05 Purdue Research Foundation Compunds and methods for treating HIV
EP3181555B1 (en) * 2011-04-21 2018-11-28 Gilead Sciences, Inc. Benzothiazole compounds and their pharmaceutical use
US9284323B2 (en) 2012-01-04 2016-03-15 Gilead Sciences, Inc. Naphthalene acetic acid derivatives against HIV infection
WO2013103724A1 (en) 2012-01-04 2013-07-11 Gilead Sciences, Inc. 2- (tert - butoxy) -2- (7 -methylquinolin- 6 - yl) acetic acid derivatives for treating aids
US9096586B2 (en) 2012-04-20 2015-08-04 Gilead Sciences, Inc. Therapeutic compounds
WO2021209563A1 (en) 2020-04-16 2021-10-21 Som Innovation Biotech, S.A. Compounds for use in the treatment of viral infections by respiratory syndrome-related coronavirus

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI1370543T1 (sl) * 2001-02-14 2007-04-30 Tibotec Pharm Ltd Sirokospektralni 2-(substituirani-amino)-benzotiazol sulfonamidni inhibitorji HIV proteaze
TWI286476B (en) * 2001-12-12 2007-09-11 Tibotec Pharm Ltd Combination of cytochrome P450 dependent protease inhibitors
KR20050025647A (ko) * 2002-08-02 2005-03-14 티보텍 파마슈티칼즈 리미티드 광범위 2-아미노-벤조티아졸 설폰아미드 hiv프로테아제 저해제
EP1670448B1 (en) * 2003-09-30 2007-11-21 Tibotec Pharmaceuticals Ltd. Hcv inhibiting sulfonamides

Also Published As

Publication number Publication date
PL2035432T3 (pl) 2012-07-31
AU2007262943B2 (en) 2012-04-12
CN101479275B (zh) 2012-03-07
JP5232776B2 (ja) 2013-07-10
TW200817416A (en) 2008-04-16
EA016387B1 (ru) 2012-04-30
UY30416A1 (es) 2008-01-31
JO2841B1 (en) 2014-09-15
US8202887B2 (en) 2012-06-19
CA2653233A1 (en) 2007-12-27
PE20080342A1 (es) 2008-04-25
EP2035432B1 (en) 2012-02-08
US20090209583A1 (en) 2009-08-20
AU2007262943A1 (en) 2007-12-27
BRPI0713487B1 (pt) 2022-07-26
TWI415851B (zh) 2013-11-21
JP2009541272A (ja) 2009-11-26
NZ573286A (en) 2011-09-30
ATE544769T1 (de) 2012-02-15
KR101419320B1 (ko) 2014-07-14
EA200970052A1 (ru) 2009-04-28
AP2008004679A0 (en) 2008-12-31
CN101479275A (zh) 2009-07-08
IL195381A (en) 2013-01-31
HK1125633A1 (US20060241273A1-20061026-C00026.png) 2009-08-14
AP2069A (en) 2009-12-08
MY146805A (en) 2012-09-28
EP2035432A1 (en) 2009-03-18
BRPI0713487A2 (US20060241273A1-20061026-C00026.png) 2012-11-13
CA2653233C (en) 2015-09-29
KR20090024257A (ko) 2009-03-06
ZA200810350B (en) 2010-05-26
MX2009000160A (es) 2009-01-23
BRPI0713487A8 (pt) 2018-01-02
UA96445C2 (ru) 2011-11-10
WO2007147884A1 (en) 2007-12-27
IL195381A0 (en) 2009-08-03
DK2035432T3 (da) 2012-05-14
SI2035432T1 (sl) 2012-06-29
CL2007001826A1 (es) 2008-01-18
ES2381129T3 (es) 2012-05-23
CY1112971T1 (el) 2016-04-13
AR061619A1 (es) 2008-09-10

Similar Documents

Publication Publication Date Title
PT2035432E (pt) 2-(amino substituído)-benzotiazole-sulfonamidas como inibidores de protease de hiv
JP5279503B2 (ja) Hivプロテアーゼインヒビターとしての置換アミノフェニルスホンアミド化合物
KR100872029B1 (ko) 광범위 2-(치환된-아미노)-벤즈옥사졸 설폰아미드 hiv프로테아제 저해제
JP5210876B2 (ja) Hivプロテアーゼインヒビターとしてのアミノフェニルスホンアミド誘導体