PT1951294T - Propriedades imunomodulatórias de células progenitoras adultas multipotentes e utilizações das mesmas - Google Patents

Propriedades imunomodulatórias de células progenitoras adultas multipotentes e utilizações das mesmas

Info

Publication number
PT1951294T
PT1951294T PT68373364T PT06837336T PT1951294T PT 1951294 T PT1951294 T PT 1951294T PT 68373364 T PT68373364 T PT 68373364T PT 06837336 T PT06837336 T PT 06837336T PT 1951294 T PT1951294 T PT 1951294T
Authority
PT
Portugal
Prior art keywords
progenitor cells
immunomodulatory properties
multipotent adult
adult progenitor
multipotent
Prior art date
Application number
PT68373364T
Other languages
English (en)
Portuguese (pt)
Original Assignee
Univ Oregon Health & Science
Abt Holding Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Oregon Health & Science, Abt Holding Co filed Critical Univ Oregon Health & Science
Publication of PT1951294T publication Critical patent/PT1951294T/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/001—Preparations to induce tolerance to non-self, e.g. prior to transplantation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0607—Non-embryonic pluripotent stem cells, e.g. MASC
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K2035/122—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells for inducing tolerance or supression of immune responses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K2035/124—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells the cells being hematopoietic, bone marrow derived or blood cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Developmental Biology & Embryology (AREA)
  • Cell Biology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Virology (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Mycology (AREA)
  • Transplantation (AREA)
  • Diabetes (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Oncology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Materials For Medical Uses (AREA)
PT68373364T 2005-11-09 2006-11-09 Propriedades imunomodulatórias de células progenitoras adultas multipotentes e utilizações das mesmas PT1951294T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US11/269,736 US8147824B2 (en) 1999-08-05 2005-11-09 Immunomodulatory properties of multipotent adult progenitor cells and uses thereof

Publications (1)

Publication Number Publication Date
PT1951294T true PT1951294T (pt) 2020-03-31

Family

ID=37808258

Family Applications (2)

Application Number Title Priority Date Filing Date
PT68373364T PT1951294T (pt) 2005-11-09 2006-11-09 Propriedades imunomodulatórias de células progenitoras adultas multipotentes e utilizações das mesmas
PT131805038T PT2684571T (pt) 2005-11-09 2006-11-09 Propriedades imunomodulatórias de células progenitoras adultas multipotentes e utilizações das mesmas

Family Applications After (1)

Application Number Title Priority Date Filing Date
PT131805038T PT2684571T (pt) 2005-11-09 2006-11-09 Propriedades imunomodulatórias de células progenitoras adultas multipotentes e utilizações das mesmas

Country Status (20)

Country Link
US (6) US8147824B2 (ja)
EP (3) EP1951294B1 (ja)
JP (3) JP5399709B2 (ja)
KR (1) KR101423786B1 (ja)
CN (3) CN104873540B (ja)
AU (1) AU2006311418B2 (ja)
BR (1) BRPI0618486B1 (ja)
CA (3) CA3206592A1 (ja)
DK (2) DK2684571T3 (ja)
ES (2) ES2778424T3 (ja)
HK (2) HK1203058A1 (ja)
HU (1) HUE055956T2 (ja)
IL (5) IL191317A (ja)
LT (1) LT1951294T (ja)
NZ (2) NZ568546A (ja)
PH (1) PH12015502169B1 (ja)
PL (2) PL2684571T3 (ja)
PT (2) PT1951294T (ja)
RU (1) RU2497530C2 (ja)
WO (1) WO2007056578A1 (ja)

Families Citing this family (76)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10638734B2 (en) 2004-01-05 2020-05-05 Abt Holding Company Multipotent adult stem cells, sources thereof, methods of obtaining and maintaining same, methods of differentiation thereof, methods of use thereof and cells derived thereof
US8252280B1 (en) 1999-08-05 2012-08-28 Regents Of The University Of Minnesota MAPC generation of muscle
US7015037B1 (en) 1999-08-05 2006-03-21 Regents Of The University Of Minnesota Multiponent adult stem cells and methods for isolation
US8147824B2 (en) * 1999-08-05 2012-04-03 Athersys, Inc. Immunomodulatory properties of multipotent adult progenitor cells and uses thereof
US7311905B2 (en) 2002-02-13 2007-12-25 Anthrogenesis Corporation Embryonic-like stem cells derived from post-partum mammalian placenta, and uses and methods of treatment using said cells
EP3299452A1 (en) 2000-12-06 2018-03-28 Anthrogenesis Corporation Method of collecting placental stem cells
CA2438153C (en) * 2001-02-14 2015-06-02 Anthrogenesis Corporation Post-partum mammalian placenta, its use and placental stem cells therefrom
EP2338983B1 (en) * 2001-02-14 2015-10-07 Anthrogenesis Corporation Renovation and repopulation of decellularized tissues and cadaveric organs by stem cells
IL157332A0 (en) * 2001-02-14 2004-02-19 Multipotent adult stem cells, sources thereof, methods of obtaining and maintaining same, methods of differentiation thereof, methods of use thereof and cells derived thereof
DE10144326B4 (de) * 2001-09-10 2005-09-22 Siemens Ag Verfahren und System zur Überwachung eines Reifenluftdrucks
US8192348B2 (en) * 2003-07-01 2012-06-05 Regents Of The University Of Minnesota Engineered blood vessels
MX343814B (es) 2005-10-13 2016-11-24 Anthrogenesis Corp Inmunomodulación usando celulas madre de la placenta.
US11000546B2 (en) 2005-11-09 2021-05-11 Athersys, Inc. Immunomodulatory properties of MAPCs and uses thereof
US10117900B2 (en) 2005-11-09 2018-11-06 Athersys, Inc. MAPC treatment of brain injuries and diseases
DK2471903T3 (en) 2005-12-29 2018-05-28 Anthrogenesis Corp Placenta stem cell populations
KR20080081088A (ko) 2005-12-29 2008-09-05 안트로제네시스 코포레이션 태반 줄기세포와 제2 세포원으로부터 얻은 줄기세포의 공동배양
EP2465922B1 (en) 2006-01-13 2018-08-01 Mesoblast International Sàrl Mesenchymal stem cells expressing tnf-alpha receptor
NZ727755A (en) 2006-01-23 2023-01-27 Abt Holding Co Mapc therapeutics without adjunctive immunosuppressive treatment
US20110171182A1 (en) * 2006-03-23 2011-07-14 Pluristem Ltd. Methods for cell expansion and uses of cells and conditioned media produced thereby for therapy
US7993918B2 (en) 2006-08-04 2011-08-09 Anthrogenesis Corporation Tumor suppression using placental stem cells
JP2010507392A (ja) 2006-10-23 2010-03-11 アントフロゲネシス コーポレーション 胎盤細胞集団で骨欠損を治療するための方法及び組成物
WO2008063675A2 (en) * 2006-11-24 2008-05-29 Regents Of The University Of Minnesota Endodermal progenitor cells
SI2120977T1 (sl) 2007-02-12 2014-01-31 Anthrogenesis Coroporation Zdravljenje vnetnih bolezni z uporabo placentarnih matičnih celic
NZ617412A (en) 2007-09-28 2015-06-26 Anthrogenesis Corp Tumor suppression using human placental perfusate and human placenta-derived intermediate natural killer cells
US8124071B2 (en) 2007-11-30 2012-02-28 New York Medical College Methods of reducing transplant rejection and cardiac allograft vasculopathy by implanting autologous stem cells
US8512696B2 (en) 2007-11-30 2013-08-20 Autologous, Llc Methods of isolating non-senescent cardiac stem cells and uses thereof
WO2009073518A1 (en) * 2007-11-30 2009-06-11 New York Medical College Methods of isolating non-senescent cardiac stem cells and uses thereof
EP2227238A2 (en) * 2007-11-30 2010-09-15 New York Medical College Compositions comprising vascular and myocyte progenitor cells and methods of their use
CA2743701A1 (en) * 2007-11-30 2009-06-11 New York Medical College Compositions comprising hdac inhibitors and methods of their use in restoring stem cell function and preventing heart failure
CA2712496C (en) 2008-01-18 2021-01-12 Wei-Shou Hu Stem cell aggregates and methods for making and using
PE20110399A1 (es) 2008-08-20 2011-06-22 Anthrogenesis Corp Tratamiento de la apoplejia utilizando celulas placentarias aisladas
AU2009283216B2 (en) 2008-08-20 2015-04-02 Celularity Inc. Improved cell composition and methods of making the same
RU2011110736A (ru) 2008-08-22 2012-09-27 Антродженезис Корпорейшн (Us) Способы и композиции для лечения костных дефектов с помощью плацентарных клеточных популяций
BRPI0922184A2 (pt) 2008-11-19 2020-08-18 Anthrogenesis Corporation célula isolada, população isolada de células, matriz ou estrutura sintética permanente ou decelularizada degradável, e , método para tratar um indivíduo
SG178064A1 (en) * 2009-07-21 2012-03-29 Abt Holding Co Use of stem cells to reduce leukocyte extravasation
US20110020292A1 (en) * 2009-07-21 2011-01-27 Abt Holding Company Use of Stem Cells to Reduce Leukocyte Extravasation
EP2529007B1 (en) 2010-01-26 2017-07-12 Anthrogenesis Corporation Treatment of bone-related cancers using placental stem cells
KR20220015489A (ko) 2010-04-07 2022-02-08 셀룰래리티 인코포레이티드 태반 줄기 세포를 사용한 혈관신생
CN102933221A (zh) 2010-04-08 2013-02-13 人类起源公司 使用胎盘干细胞治疗结节病
SG185526A1 (en) 2010-05-12 2012-12-28 Abt Holding Co Modulation of splenocytes in cell therapy
BR112013000822B1 (pt) 2010-07-13 2021-02-23 Anthrogenesis Corporation Método in vitro em duas etapas para a produção de uma população decélulas exterminadoras naturais (nk) ativadas
US8642027B2 (en) 2010-09-01 2014-02-04 Stemnion, Inc. Compositions and methods for modulating ischemic injury
WO2012048298A2 (en) 2010-10-08 2012-04-12 Caridianbct, Inc. Methods and systems of growing and harvesting cells in a hollow fiber bioreactor system with control conditions
EP2658557A1 (en) 2010-12-31 2013-11-06 Anthrogenesis Corporation Enhancement of placental stem cell potency using modulatory rna molecules
CN104220081A (zh) 2011-06-01 2014-12-17 人类起源公司 利用胎盘干细胞治疗疼痛
KR102073530B1 (ko) * 2011-06-06 2020-02-04 리제네시스 비브이비에이 중공 섬유 생물 반응기에서의 줄기 세포의 확장
US9925221B2 (en) 2011-09-09 2018-03-27 Celularity, Inc. Treatment of amyotrophic lateral sclerosis using placental stem cells
JP5968458B2 (ja) * 2011-12-01 2016-08-10 アール バイオ カンパニー リミテッドＲ Ｂｉｏ Ｃｏ．， Ｌｔｄ． 幹細胞を若くするための培地組成物
EP2802647B1 (en) 2012-01-13 2020-10-28 The General Hospital Corporation Isolated human lung progenitor cells and uses thereof
WO2014015318A1 (en) * 2012-07-19 2014-01-23 Bluebird Bio, Inc. Soluble compounds for improved gene therapy methods
CN115282165A (zh) 2013-02-05 2022-11-04 细胞结构公司 来自胎盘的自然杀伤细胞
EP2956147B1 (en) 2013-02-12 2022-08-24 Reneuron Limited Method of producing microparticles
ES2827250T3 (es) * 2013-04-12 2021-05-20 Houston Methodist Hospital Mejora de órganos para trasplante
WO2014184666A2 (en) * 2013-04-30 2014-11-20 Katholieke Universiteit Leuven Cell therapy for myelodysplastic syndromes
US9617506B2 (en) 2013-11-16 2017-04-11 Terumo Bct, Inc. Expanding cells in a bioreactor
ITFI20130303A1 (it) * 2013-12-24 2015-06-25 Azienda Ospedaliero Universitaria M Eyer Metodica per l¿isolamento, purificazione ed amplificazione di progenitori renali cd133+cd24+ dalle urine di pazienti affetti da malattie renali.
US11008547B2 (en) 2014-03-25 2021-05-18 Terumo Bct, Inc. Passive replacement of media
JP6830059B2 (ja) 2014-09-26 2021-02-17 テルモ ビーシーティー、インコーポレーテッド スケジュール化された細胞フィーディング
RU2580640C1 (ru) * 2014-12-25 2016-04-10 Федеральное государственное бюджетное учреждение "Федеральный научный центр трансплантологии и искусственных органов имени академика В.И. Шумакова" Министерства здравоохранения Российской Федерации Способ профилактики гуморального отторжения при аво-несовместимой трансплантации печени детям раннего возраста
WO2017004592A1 (en) 2015-07-02 2017-01-05 Terumo Bct, Inc. Cell growth with mechanical stimuli
KR20180102661A (ko) 2016-01-21 2018-09-17 에이비티 홀딩 컴퍼니 상처 치유를 위한 줄기 세포
US11965175B2 (en) 2016-05-25 2024-04-23 Terumo Bct, Inc. Cell expansion
US11104874B2 (en) 2016-06-07 2021-08-31 Terumo Bct, Inc. Coating a bioreactor
US11685883B2 (en) 2016-06-07 2023-06-27 Terumo Bct, Inc. Methods and systems for coating a cell growth surface
US10767164B2 (en) 2017-03-30 2020-09-08 The Research Foundation For The State University Of New York Microenvironments for self-assembly of islet organoids from stem cells differentiation
US11624046B2 (en) 2017-03-31 2023-04-11 Terumo Bct, Inc. Cell expansion
CN117247899A (zh) 2017-03-31 2023-12-19 泰尔茂比司特公司 细胞扩增
CN110494556B (zh) 2017-04-03 2024-04-30 株式会社钟化 包含间充质系干细胞的细胞群、其制造方法、以及医药组合物
CN107714726A (zh) * 2017-10-16 2018-02-23 中国科学院广州生物医药与健康研究院 一种重塑骨髓微环境的方法
US20200360444A1 (en) 2017-12-28 2020-11-19 Kaneka Corporation Cell population including adhesive stem cells, production method therefor and pharmaceutical composition
WO2019132026A1 (ja) 2017-12-28 2019-07-04 株式会社カネカ 接着性幹細胞を含む細胞集団とその製造方法、及び医薬組成物
CN109735611A (zh) * 2018-12-19 2019-05-10 珠海铂华生物工程有限公司 一种用于检测骨髓衰竭综合征的基因组合、引物库、构建高通量测序文库的方法及其应用
WO2020184350A1 (ja) 2019-03-08 2020-09-17 株式会社カネカ 多能性幹細胞の大量培養
CN111964227B (zh) * 2020-07-27 2021-12-21 青岛海尔空调器有限总公司 一种空气循环控制方法、系统和装置
WO2023081420A1 (en) 2021-11-05 2023-05-11 Abt Holding Company Culture-expanded canine progenitor cells and related methods
WO2024046355A1 (en) * 2022-09-02 2024-03-07 Medical And Pharmaceutical Industry Technology And Development Center Use of composition including mesenchymal stem cells for alleviating myelofibrosis

Family Cites Families (52)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4353888A (en) 1980-12-23 1982-10-12 Sefton Michael V Encapsulation of live animal cells
US4749620A (en) 1984-02-15 1988-06-07 Massachusetts Institute Of Technology Encapsulated active material system
US4744933A (en) 1984-02-15 1988-05-17 Massachusetts Institute Of Technology Process for encapsulation and encapsulated active material system
JPH0628570B2 (ja) 1986-02-13 1994-04-20 雪印乳業株式会社 カプセル体の製造方法及び装置
EP0301777A1 (en) 1987-07-28 1989-02-01 Queen's University At Kingston Multiple membrane microencapsulation
US5089272A (en) 1989-03-29 1992-02-18 Snow Brand Milk Products Co., Ltd. Process for producing capsules having a permeability-controllable membrane
US5084350A (en) 1990-02-16 1992-01-28 The Royal Institution For The Advance Of Learning (Mcgill University) Method for encapsulating biologically active material including cells
US5578442A (en) 1992-03-23 1996-11-26 Vivorx, Inc. Graft copolymers of polycationic species and water-soluble polymers, and use therefor
US6270766B1 (en) * 1992-10-08 2001-08-07 The Kennedy Institute Of Rheumatology Anti-TNF antibodies and methotrexate in the treatment of arthritis and crohn's disease
ES2178654T3 (es) 1993-08-12 2003-01-01 Neurotech Sa Capsulas biocompatibles inmonoaisladoras que contienen celulas geneticamente alteradas para el suministro de moleculas biologicamente activas.
JPH07316051A (ja) 1994-05-23 1995-12-05 Kanegafuchi Chem Ind Co Ltd 免疫抑制剤としてのベルベリン
IN184685B (ja) 1996-02-14 2000-09-23 Nat Inst Immunology
US20030103951A1 (en) 1997-07-14 2003-06-05 Osiris Therapeutics, Inc. Cardiac muscle regeneration using mesenchymal stem cells
US7514074B2 (en) 1997-07-14 2009-04-07 Osiris Therapeutics, Inc. Cardiac muscle regeneration using mesenchymal stem cells
AU8401498A (en) 1997-07-14 1999-02-10 Osiris Therapeutics, Inc. Cardiac muscle regeneration using mesenchymal stem cells
AU1508899A (en) 1997-12-02 1999-06-16 Chong Kun Dang Corporation Pharmaceutical composition comprising cyclosporin solid-state microemulsion
ES2237089T3 (es) 1998-03-13 2005-07-16 Osiris Therapeutics, Inc. Usos para celulas madre mesenquimatosas humanas no autologas.
ATE316795T1 (de) * 1998-03-18 2006-02-15 Osiris Therapeutics Inc Mesenchymale stammzellen für die prävention und behandlung von immunantworten bei transplantationen
US6368636B1 (en) 1998-03-18 2002-04-09 Osiris Therapeutics, Inc. Mesenchymal stem cells for prevention and treatment of immune responses in transplantation
JP2002510655A (ja) 1998-04-03 2002-04-09 オシリス セラピューティクス，インコーポレイテッド 免疫抑制剤としての間葉幹細胞によるｔ細胞応答を阻害する方法とその利用
JP2002510747A (ja) * 1998-04-08 2002-04-09 メタボリックス，インコーポレイテッド バイオポリマーの分離および精製のための方法
CA2244554A1 (en) * 1998-07-30 2000-01-30 Vasogen Inc. Inhibition of graft versus host disease
US6060364A (en) * 1999-03-02 2000-05-09 Advanced Micro Devices, Inc. Fast Mosfet with low-doped source/drain
WO2001011011A2 (en) 1999-08-05 2001-02-15 Mcl Llc Multipotent adult stem cells and methods for isolation
US7927587B2 (en) 1999-08-05 2011-04-19 Regents Of The University Of Minnesota MAPC administration for the treatment of lysosomal storage disorders
US8075881B2 (en) 1999-08-05 2011-12-13 Regents Of The University Of Minnesota Use of multipotent adult stem cells in treatment of myocardial infarction and congestive heart failure
US7015037B1 (en) 1999-08-05 2006-03-21 Regents Of The University Of Minnesota Multiponent adult stem cells and methods for isolation
US8147824B2 (en) * 1999-08-05 2012-04-03 Athersys, Inc. Immunomodulatory properties of multipotent adult progenitor cells and uses thereof
US6685936B2 (en) 1999-10-12 2004-02-03 Osiris Therapeutics, Inc. Suppressor cells induced by culture with mesenchymal stem cells for treatment of immune responses in transplantation
AU2002232405A1 (en) 2000-11-20 2002-05-27 California Institute Of Technology Artery smooth muscle- and vein smooth muscle-specific proteins and uses therefor
US20030044843A1 (en) 2001-01-09 2003-03-06 Mitsubishi Pharma Corporation Novel proteome analysis method and devices therefor
IL157332A0 (en) 2001-02-14 2004-02-19 Multipotent adult stem cells, sources thereof, methods of obtaining and maintaining same, methods of differentiation thereof, methods of use thereof and cells derived thereof
US9969980B2 (en) 2001-09-21 2018-05-15 Garnet Biotherapeutics Cell populations which co-express CD49c and CD90
EP1471970A4 (en) 2002-01-14 2006-08-02 Univ Illinois NOVEL MULTIPOTENT STEM CELLS OF MAMMALIAN ORIGIN, METHODS OF PREPARATION AND METHODS OF ADMINISTRATION OF SAID CELLS
US20040037811A1 (en) 2002-08-22 2004-02-26 The Cleveland Clinic Foundation Stromal cell-derived factor-1 mediates stem cell homing and tissue regeneration in ischemic cardiomyopathy
US7105037B2 (en) 2002-10-31 2006-09-12 Advanced Technology Materials, Inc. Semiconductor manufacturing facility utilizing exhaust recirculation
WO2004069172A2 (en) 2003-01-30 2004-08-19 The Government of the United States of America as represented by the Department of Veterans Affairs Multilineage-inducible cells and uses thereof
US20070020608A1 (en) 2003-05-08 2007-01-25 Peter Eriksson Method for the generation of neural progenitor cells
ES2600555T3 (es) 2003-06-27 2017-02-09 DePuy Synthes Products, Inc. Reparación y regeneración de tejido ocular usando células derivadas del post parto
US8426200B2 (en) * 2003-07-02 2013-04-23 Regents Of The University Of Minnesota Neuronal differentiation of stem cells
EP1737947B9 (en) 2004-04-21 2012-04-25 Regents Of The University Of Minnesota Mapc generation of lung tissue
WO2006121428A1 (en) 2005-05-05 2006-11-16 Regents Of The University Of Minnesota Use of nk cell inhibition to facilitate persistence of engrafted mhc- i negative cells
US20080311084A1 (en) 2005-05-05 2008-12-18 Verfaillie Catherine M Mapc Engraftment in the Hematopoietic System
TW200726474A (en) 2005-07-15 2007-07-16 Cognate Therapeutics Inc The immunophenotype and immunogenicity of human adipose derived cells
WO2007047465A1 (en) 2005-10-13 2007-04-26 Anthrogenesis Corporation Production of oligodendrocytes from placenta-derived stem cells
US10117900B2 (en) 2005-11-09 2018-11-06 Athersys, Inc. MAPC treatment of brain injuries and diseases
US11000546B2 (en) 2005-11-09 2021-05-11 Athersys, Inc. Immunomodulatory properties of MAPCs and uses thereof
NZ727755A (en) 2006-01-23 2023-01-27 Abt Holding Co Mapc therapeutics without adjunctive immunosuppressive treatment
US7993918B2 (en) 2006-08-04 2011-08-09 Anthrogenesis Corporation Tumor suppression using placental stem cells
SI2120977T1 (sl) 2007-02-12 2014-01-31 Anthrogenesis Coroporation Zdravljenje vnetnih bolezni z uporabo placentarnih matičnih celic
WO2010082787A2 (ko) 2009-01-15 2010-07-22 코아스템(주) 연골줄기세포를 유효성분으로 포함하는 골질환 치료용 또는 항염증용 약제학적 조성물
EP2241617A1 (en) 2009-04-06 2010-10-20 Rijksuniversiteit Groningen Multipotent cells derived from blood and methods and uses related thereto

Also Published As

Publication number Publication date
KR20080092336A (ko) 2008-10-15
HK1214166A1 (zh) 2016-07-22
HUE055956T2 (hu) 2022-01-28
CN104095878B (zh) 2020-01-21
US20120135043A1 (en) 2012-05-31
HK1203058A1 (en) 2015-10-16
IL236832A (en) 2017-08-31
JP6342880B2 (ja) 2018-06-13
JP2013256510A (ja) 2013-12-26
EP2684571A1 (en) 2014-01-15
CN101336112A (zh) 2008-12-31
ES2884703T3 (es) 2021-12-10
US9962407B2 (en) 2018-05-08
PL1951294T3 (pl) 2020-08-24
IL249572A0 (en) 2017-02-28
ES2778424T3 (es) 2020-08-10
EP1951294B1 (en) 2019-12-25
CN104873540A (zh) 2015-09-02
LT1951294T (lt) 2020-04-10
AU2006311418A1 (en) 2007-05-18
US9808485B2 (en) 2017-11-07
PH12015502169A1 (en) 2017-04-24
RU2497530C2 (ru) 2013-11-10
EP2684571B1 (en) 2021-05-26
PT2684571T (pt) 2021-08-30
BRPI0618486A2 (pt) 2011-08-30
CA3028315C (en) 2023-09-05
AU2006311418B2 (en) 2013-03-14
RU2008122943A (ru) 2009-12-20
JP5399709B2 (ja) 2014-01-29
IL191317A0 (en) 2008-12-29
US20090104163A1 (en) 2009-04-23
NZ568546A (en) 2012-06-29
BRPI0618486B1 (pt) 2021-11-30
CA2628254C (en) 2023-06-20
JP2016135763A (ja) 2016-07-28
IL191317A (en) 2015-03-31
KR101423786B1 (ko) 2014-07-25
CA3028315A1 (en) 2007-05-18
US8147824B2 (en) 2012-04-03
CN104095878A (zh) 2014-10-15
IL276705A (en) 2020-09-30
CA3206592A1 (en) 2007-05-18
PL2684571T3 (pl) 2022-01-10
CN104873540B (zh) 2019-11-15
JP2009514979A (ja) 2009-04-09
US20150118193A1 (en) 2015-04-30
PH12015502169B1 (en) 2017-04-24
US11197889B2 (en) 2021-12-14
CA2628254A1 (en) 2007-05-18
IL249572B (en) 2020-08-31
WO2007056578A1 (en) 2007-05-18
DK2684571T3 (da) 2021-08-30
IL289024A (en) 2022-02-01
JP5897514B2 (ja) 2016-03-30
US20060263337A1 (en) 2006-11-23
EP3808373A1 (en) 2021-04-21
DK1951294T3 (da) 2020-03-23
US20210346429A1 (en) 2021-11-11
IL276705B (en) 2022-04-01
CN101336112B (zh) 2015-05-20
NZ596022A (en) 2013-06-28
US20180055881A1 (en) 2018-03-01
EP1951294A1 (en) 2008-08-06

Similar Documents

Publication Publication Date Title
IL289024A (en) Immunological properties of multipotent cells and their use
IL267138A (en) Improved composition of cells and methods for its preparation
IL255813A (en) Compositions of 5-fluorocytosine and their uses
ZA200908904B (en) Multipotent/pluripotent cells and methods
PT2066399T (pt) Dispositivos de eletroporação e métodos de usar os mesmos para eletroporação de células em mamíferos
EP1856247A4 (en) REGULATION OF AUTOPHAGIA AND CELL SURVIVAL
IL201018A0 (en) Novel asparaginases and uses thereof
IL195067A (en) Elusive progenitor cells and immune modulators
EP2262039A4 (en) Cell selector and cell with it
IL194667A (en) Preparations containing unalloyed allogeneic cells and their use in the treatment of infection
HK1114641A1 (en) Activating agent of stem cells and or progenitor cells
EP1907533A4 (en) PRE-CELL CELLS AND USES THEREOF
EP2204398A4 (en) CAMPTOTHECIN POLYMER DERIVATIVE AND USES THEREOF
EP2117599A4 (en) MEMBRANE (S) AND USE THEREOF (S) -CI
GB0608143D0 (en) Carcinogen solvents in reducing the carcinogen concentration of cells
GB0611279D0 (en) Carcinogen solvents in reducing the carcinogen concentration of cells
GB0716515D0 (en) Regionalised endoderm cells and uses thereof
GB0811278D0 (en) Permissive cells and uses thereof
GB0820492D0 (en) Cell compositions and uses thereof
AU2008901168A0 (en) Up and outz
AU2007903401A0 (en) Bicyclic pyrimidinodes and uses thereof (3)
GB0809852D0 (en) Regionalised endoderm cells and uses thereof