PT2684571T - Propriedades imunomodulatórias de células progenitoras adultas multipotentes e utilizações das mesmas - Google Patents
Propriedades imunomodulatórias de células progenitoras adultas multipotentes e utilizações das mesmasInfo
- Publication number
- PT2684571T PT2684571T PT131805038T PT13180503T PT2684571T PT 2684571 T PT2684571 T PT 2684571T PT 131805038 T PT131805038 T PT 131805038T PT 13180503 T PT13180503 T PT 13180503T PT 2684571 T PT2684571 T PT 2684571T
- Authority
- PT
- Portugal
- Prior art keywords
- progenitor cells
- immunomodulatory properties
- multipotent adult
- adult progenitor
- multipotent
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/001—Preparations to induce tolerance to non-self, e.g. prior to transplantation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0607—Non-embryonic pluripotent stem cells, e.g. MASC
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K2035/122—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells for inducing tolerance or supression of immune responses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K2035/124—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells the cells being hematopoietic, bone marrow derived or blood cells
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Cell Biology (AREA)
- Developmental Biology & Embryology (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Epidemiology (AREA)
- Hematology (AREA)
- Virology (AREA)
- Microbiology (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Transplantation (AREA)
- Mycology (AREA)
- Diabetes (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Pathology (AREA)
- Radiology & Medical Imaging (AREA)
- Oncology (AREA)
- Physical Education & Sports Medicine (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Materials For Medical Uses (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US11/269,736 US8147824B2 (en) | 1999-08-05 | 2005-11-09 | Immunomodulatory properties of multipotent adult progenitor cells and uses thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
PT2684571T true PT2684571T (pt) | 2021-08-30 |
Family
ID=37808258
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT131805038T PT2684571T (pt) | 2005-11-09 | 2006-11-09 | Propriedades imunomodulatórias de células progenitoras adultas multipotentes e utilizações das mesmas |
PT68373364T PT1951294T (pt) | 2005-11-09 | 2006-11-09 | Propriedades imunomodulatórias de células progenitoras adultas multipotentes e utilizações das mesmas |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT68373364T PT1951294T (pt) | 2005-11-09 | 2006-11-09 | Propriedades imunomodulatórias de células progenitoras adultas multipotentes e utilizações das mesmas |
Country Status (20)
Country | Link |
---|---|
US (6) | US8147824B2 (pt) |
EP (3) | EP1951294B1 (pt) |
JP (3) | JP5399709B2 (pt) |
KR (1) | KR101423786B1 (pt) |
CN (3) | CN104873540B (pt) |
AU (1) | AU2006311418B2 (pt) |
BR (1) | BRPI0618486B1 (pt) |
CA (3) | CA2628254C (pt) |
DK (2) | DK1951294T3 (pt) |
ES (2) | ES2778424T3 (pt) |
HK (2) | HK1203058A1 (pt) |
HU (1) | HUE055956T2 (pt) |
IL (5) | IL191317A (pt) |
LT (1) | LT1951294T (pt) |
NZ (2) | NZ568546A (pt) |
PH (1) | PH12015502169A1 (pt) |
PL (2) | PL2684571T3 (pt) |
PT (2) | PT2684571T (pt) |
RU (1) | RU2497530C2 (pt) |
WO (1) | WO2007056578A1 (pt) |
Families Citing this family (77)
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US8252280B1 (en) | 1999-08-05 | 2012-08-28 | Regents Of The University Of Minnesota | MAPC generation of muscle |
US8147824B2 (en) * | 1999-08-05 | 2012-04-03 | Athersys, Inc. | Immunomodulatory properties of multipotent adult progenitor cells and uses thereof |
US10638734B2 (en) | 2004-01-05 | 2020-05-05 | Abt Holding Company | Multipotent adult stem cells, sources thereof, methods of obtaining and maintaining same, methods of differentiation thereof, methods of use thereof and cells derived thereof |
US7015037B1 (en) | 1999-08-05 | 2006-03-21 | Regents Of The University Of Minnesota | Multiponent adult stem cells and methods for isolation |
EP2322601A1 (en) | 2000-12-06 | 2011-05-18 | Anthrogenesis Corporation | Method of collecting placental stem cells |
US7311905B2 (en) | 2002-02-13 | 2007-12-25 | Anthrogenesis Corporation | Embryonic-like stem cells derived from post-partum mammalian placenta, and uses and methods of treatment using said cells |
EP2338983B1 (en) * | 2001-02-14 | 2015-10-07 | Anthrogenesis Corporation | Renovation and repopulation of decellularized tissues and cadaveric organs by stem cells |
CA2438153C (en) * | 2001-02-14 | 2015-06-02 | Anthrogenesis Corporation | Post-partum mammalian placenta, its use and placental stem cells therefrom |
JP2004529621A (ja) * | 2001-02-14 | 2004-09-30 | ティー ファークト,レオ | 多能性成体幹細胞、その起源、それを得る方法および維持する方法、それを分化させる方法、その使用法、ならびにそれ由来の細胞 |
DE10144326B4 (de) * | 2001-09-10 | 2005-09-22 | Siemens Ag | Verfahren und System zur Überwachung eines Reifenluftdrucks |
US7682803B2 (en) | 2005-10-13 | 2010-03-23 | Anthrogenesis Corporation | Immunomodulation using placental stem cells |
US8192348B2 (en) * | 2003-07-01 | 2012-06-05 | Regents Of The University Of Minnesota | Engineered blood vessels |
US10117900B2 (en) | 2005-11-09 | 2018-11-06 | Athersys, Inc. | MAPC treatment of brain injuries and diseases |
US11000546B2 (en) | 2005-11-09 | 2021-05-11 | Athersys, Inc. | Immunomodulatory properties of MAPCs and uses thereof |
CN101389754A (zh) | 2005-12-29 | 2009-03-18 | 人类起源公司 | 胎盘干细胞和第二来源干细胞的联合培养 |
CN101395266B (zh) | 2005-12-29 | 2018-06-15 | 人类起源公司 | 胎盘干细胞群 |
AU2007208504B2 (en) * | 2006-01-13 | 2011-04-21 | Mesoblast International Sarl | Mesenchymal stem cells expressing TNF-alpha receptor |
NZ727755A (en) | 2006-01-23 | 2023-01-27 | Abt Holding Co | Mapc therapeutics without adjunctive immunosuppressive treatment |
US20110171182A1 (en) * | 2006-03-23 | 2011-07-14 | Pluristem Ltd. | Methods for cell expansion and uses of cells and conditioned media produced thereby for therapy |
US7993918B2 (en) | 2006-08-04 | 2011-08-09 | Anthrogenesis Corporation | Tumor suppression using placental stem cells |
CN101631852A (zh) | 2006-10-23 | 2010-01-20 | 人类起源公司 | 用胎盘细胞群治疗骨缺损的方法和组合物 |
US9005964B2 (en) * | 2006-11-24 | 2015-04-14 | Regents Of The University Of Minnesota | Endodermal progenitor cells |
EP2630959A1 (en) | 2007-02-12 | 2013-08-28 | Anthrogenesis Corporation | Treatment of inflammatory diseases using placental stem cells |
KR20210127819A (ko) | 2007-09-28 | 2021-10-22 | 안트로제네시스 코포레이션 | 인간 태반 관류액 및 인간 태반-유래 중간체 천연 킬러 세포를 사용한 종양 억제 방법 |
EP2245140A2 (en) * | 2007-11-30 | 2010-11-03 | New York Medical College | Compositions comprising hdac inhibitors and methods of their use in restoring stem cell function and preventing heart failure |
US20090180998A1 (en) * | 2007-11-30 | 2009-07-16 | Piero Anversa | Methods of isolating non-senescent cardiac stem cells and uses thereof |
US8512696B2 (en) * | 2007-11-30 | 2013-08-20 | Autologous, Llc | Methods of isolating non-senescent cardiac stem cells and uses thereof |
WO2009073594A1 (en) * | 2007-11-30 | 2009-06-11 | New York Medical College | Methods of reducing transplant rejection and cardiac allograft vasculopathy by implanting autologous stem cells |
CA2743698A1 (en) | 2007-11-30 | 2009-06-11 | New York Medical College | Compositions comprising vascular and myocyte progenitor cells and methods of their use |
AU2009205886B2 (en) | 2008-01-18 | 2015-08-27 | Katholieke Universiteit Leuven | Stem cell aggregates and methods for making and using |
RU2558778C2 (ru) | 2008-08-20 | 2015-08-10 | Антродженезис Корпорейшн | Лечение инсульта с использованием изолированных плацентарных клеток |
KR20210010648A (ko) | 2008-08-20 | 2021-01-27 | 안트로제네시스 코포레이션 | 개선된 세포 조성물 및 그의 제조 방법 |
EP2331109B1 (en) | 2008-08-22 | 2013-05-29 | Anthrogenesis Corporation | Methods and compositions for treatment of bone defects with placental cell populations |
EP2367932B1 (en) | 2008-11-19 | 2019-06-12 | Celularity, Inc. | Amnion derived adherent cells |
JP6243119B2 (ja) * | 2009-07-21 | 2017-12-06 | エイビーティー ホールディング カンパニー | 白血球溢出を低下させる幹細胞の使用 |
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WO2011094181A1 (en) | 2010-01-26 | 2011-08-04 | Anthrogenesis Corporation | Treatment of bone-related cancers using placental stem cells |
CN107699541A (zh) | 2010-04-07 | 2018-02-16 | 人类起源公司 | 使用胎盘干细胞的血管生成 |
MX2012011543A (es) | 2010-04-08 | 2013-05-06 | Anthrogenesis Corp | Tratamiento de sarcoidosis empleando celulas madre placentarias. |
SG10201913920PA (en) | 2010-05-12 | 2020-03-30 | Abt Holding Co | Modulation of splenocytes in cell therapy |
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JP2024511064A (ja) | 2021-03-23 | 2024-03-12 | テルモ ビーシーティー、インコーポレーテッド | 細胞捕獲及び増殖 |
EP4426815A1 (en) | 2021-11-05 | 2024-09-11 | Healios K.K. | Culture-expanded canine progenitor cells and related methods |
TW202417616A (zh) * | 2022-09-02 | 2024-05-01 | 財團法人醫藥工業技術發展中心 | 包含間質幹細胞的組成物在緩解骨髓纖維化上的用途 |
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