PT1888541E - Compostos de benzo(d)isoxazol-3-il-amina substituídos como analgésicos - Google Patents
Compostos de benzo(d)isoxazol-3-il-amina substituídos como analgésicos Download PDFInfo
- Publication number
- PT1888541E PT1888541E PT06742972T PT06742972T PT1888541E PT 1888541 E PT1888541 E PT 1888541E PT 06742972 T PT06742972 T PT 06742972T PT 06742972 T PT06742972 T PT 06742972T PT 1888541 E PT1888541 E PT 1888541E
- Authority
- PT
- Portugal
- Prior art keywords
- isoxazol
- benzo
- amine compounds
- receptor ligands
- vanilloid receptor
- Prior art date
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
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- A—HUMAN NECESSITIES
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- A61P25/08—Antiepileptics; Anticonvulsants
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- A—HUMAN NECESSITIES
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- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
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- A61P25/16—Anti-Parkinson drugs
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- A—HUMAN NECESSITIES
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- A61P25/22—Anxiolytics
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- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P25/36—Opioid-abuse
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- A—HUMAN NECESSITIES
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- A61P27/02—Ophthalmic agents
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- A—HUMAN NECESSITIES
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- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
- C07D261/20—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings condensed with carbocyclic rings or ring systems
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE102005023589 | 2005-05-18 | ||
DE102005038947A DE102005038947A1 (de) | 2005-05-18 | 2005-08-16 | Substituierte Benzo[d]isoxazol-3-yl-amin-Verbindungen und deren Verwendung in Arzneimitteln |
Publications (1)
Publication Number | Publication Date |
---|---|
PT1888541E true PT1888541E (pt) | 2009-11-10 |
Family
ID=36699120
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT06742972T PT1888541E (pt) | 2005-05-18 | 2006-05-18 | Compostos de benzo(d)isoxazol-3-il-amina substituídos como analgésicos |
PT06753695T PT1881967E (pt) | 2005-05-18 | 2006-05-18 | Compostos substituídos de benzo(d)isoxazol-3-ilamina como analgésicos |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT06753695T PT1881967E (pt) | 2005-05-18 | 2006-05-18 | Compostos substituídos de benzo(d)isoxazol-3-ilamina como analgésicos |
Country Status (16)
Country | Link |
---|---|
US (2) | US7977360B2 (pt) |
EP (2) | EP1888541B1 (pt) |
JP (2) | JP2008540597A (pt) |
AT (2) | ATE438633T1 (pt) |
AU (1) | AU2006249065B2 (pt) |
CA (2) | CA2608773A1 (pt) |
CY (2) | CY1109568T1 (pt) |
DE (3) | DE102005038947A1 (pt) |
DK (2) | DK1888541T3 (pt) |
ES (2) | ES2331259T3 (pt) |
HK (1) | HK1112238A1 (pt) |
PL (2) | PL1881967T3 (pt) |
PT (2) | PT1888541E (pt) |
RU (1) | RU2416607C2 (pt) |
SI (2) | SI1881967T1 (pt) |
WO (2) | WO2006122800A1 (pt) |
Families Citing this family (46)
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DE102005038947A1 (de) * | 2005-05-18 | 2006-11-30 | Grünenthal GmbH | Substituierte Benzo[d]isoxazol-3-yl-amin-Verbindungen und deren Verwendung in Arzneimitteln |
US20100080773A1 (en) | 2008-09-26 | 2010-04-01 | Sdg, Inc. | Orally Bioavailable Lipid-Based Constructs |
US8557872B2 (en) | 2008-01-28 | 2013-10-15 | Amorepacific Corporation | Compounds, isomer thereof, or pharmaceutically acceptable salts thereof as vanilloid receptor antagonist; and pharmaceutical compositions containing the same |
JP5438103B2 (ja) | 2008-07-02 | 2014-03-12 | アモーレパシフィック コーポレイション | バニロイド受容体アンタゴニストとしての新規化合物、その異性体またはその薬学的に許容される塩、並びにそれを含む医薬組成物 |
US8349852B2 (en) | 2009-01-13 | 2013-01-08 | Novartis Ag | Quinazolinone derivatives useful as vanilloid antagonists |
WO2010102778A2 (de) | 2009-03-10 | 2010-09-16 | Grünenthal GmbH | Substituierte 3-aminoisoxazolopyridine als kcnq2/3 modulatoren |
TWI504395B (zh) | 2009-03-10 | 2015-10-21 | Substituted 3-amino-2-mercaptoquinoline as a KCNQ2 / 3 modifier | |
TWI461197B (zh) | 2009-03-12 | 2014-11-21 | 2-mercaptoquinoline-3-carboxamide as a KCNQ2 / 3 modifier | |
TW201038565A (en) | 2009-03-12 | 2010-11-01 | Gruenenthal Gmbh | Substituted 2-mercapto-3-aminopyridines as KCNQ2/3 modulators |
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KR101663436B1 (ko) | 2012-07-06 | 2016-10-06 | 제넨테크, 인크. | N-치환된 벤즈아미드 및 이의 사용 방법 |
RU2015143906A (ru) | 2013-03-14 | 2017-04-18 | Дженентек, Инк. | Замещенные триазолопиридины и способы их применения |
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GB0319150D0 (en) * | 2003-08-14 | 2003-09-17 | Glaxo Group Ltd | Novel compounds |
JP2007529468A (ja) * | 2004-03-16 | 2007-10-25 | ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ | ベンズイソオキサゾール |
US7759337B2 (en) * | 2005-03-03 | 2010-07-20 | Amgen Inc. | Phthalazine compounds and methods of use |
DE102005038947A1 (de) * | 2005-05-18 | 2006-11-30 | Grünenthal GmbH | Substituierte Benzo[d]isoxazol-3-yl-amin-Verbindungen und deren Verwendung in Arzneimitteln |
DE102005026194A1 (de) * | 2005-06-06 | 2006-12-07 | Grünenthal GmbH | Substituierte N-Benzo[d]isoxazol-3-yl-amin-Derivate und deren Verwendung zur Herstellung von Arzneimitteln |
US7989461B2 (en) * | 2005-12-23 | 2011-08-02 | Amgen Inc. | Substituted quinazolinamine compounds for the treatment of cancer |
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2005
- 2005-08-16 DE DE102005038947A patent/DE102005038947A1/de not_active Withdrawn
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2006
- 2006-05-18 JP JP2008511637A patent/JP2008540597A/ja not_active Ceased
- 2006-05-18 WO PCT/EP2006/004700 patent/WO2006122800A1/de active Application Filing
- 2006-05-18 EP EP06742972A patent/EP1888541B1/de not_active Not-in-force
- 2006-05-18 SI SI200630725T patent/SI1881967T1/sl unknown
- 2006-05-18 JP JP2008511638A patent/JP2008540598A/ja not_active Ceased
- 2006-05-18 DE DE502006004453T patent/DE502006004453D1/de active Active
- 2006-05-18 EP EP06753695A patent/EP1881967B1/de not_active Not-in-force
- 2006-05-18 DK DK06742972T patent/DK1888541T3/da active
- 2006-05-18 RU RU2007146385/04A patent/RU2416607C2/ru not_active IP Right Cessation
- 2006-05-18 CA CA002608773A patent/CA2608773A1/en not_active Abandoned
- 2006-05-18 CA CA002608386A patent/CA2608386A1/en not_active Abandoned
- 2006-05-18 AT AT06742972T patent/ATE438633T1/de active
- 2006-05-18 AT AT06753695T patent/ATE466002T1/de active
- 2006-05-18 PT PT06742972T patent/PT1888541E/pt unknown
- 2006-05-18 AU AU2006249065A patent/AU2006249065B2/en not_active Ceased
- 2006-05-18 US US11/914,636 patent/US7977360B2/en not_active Expired - Fee Related
- 2006-05-18 DE DE502006006854T patent/DE502006006854D1/de active Active
- 2006-05-18 ES ES06742972T patent/ES2331259T3/es active Active
- 2006-05-18 PT PT06753695T patent/PT1881967E/pt unknown
- 2006-05-18 PL PL06753695T patent/PL1881967T3/pl unknown
- 2006-05-18 PL PL06742972T patent/PL1888541T3/pl unknown
- 2006-05-18 DK DK06753695.3T patent/DK1881967T3/da active
- 2006-05-18 SI SI200630455T patent/SI1888541T1/sl unknown
- 2006-05-18 WO PCT/EP2006/004698 patent/WO2006122799A1/de active Application Filing
- 2006-05-18 ES ES06753695T patent/ES2344272T3/es active Active
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2007
- 2007-11-16 US US11/941,331 patent/US7696238B2/en not_active Expired - Fee Related
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2008
- 2008-07-04 HK HK08107419.0A patent/HK1112238A1/xx not_active IP Right Cessation
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2009
- 2009-11-05 CY CY20091101144T patent/CY1109568T1/el unknown
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2010
- 2010-07-15 CY CY20101100664T patent/CY1110209T1/el unknown
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