PT1843749E - Composições de libertação controlada para interferão à base de copolímeros de blocos de pegt/pbt - Google Patents

Composições de libertação controlada para interferão à base de copolímeros de blocos de pegt/pbt Download PDF

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Publication number
PT1843749E
PT1843749E PT06700417T PT06700417T PT1843749E PT 1843749 E PT1843749 E PT 1843749E PT 06700417 T PT06700417 T PT 06700417T PT 06700417 T PT06700417 T PT 06700417T PT 1843749 E PT1843749 E PT 1843749E
Authority
PT
Portugal
Prior art keywords
composition
pegt
controlled release
block copolymers
release compositions
Prior art date
Application number
PT06700417T
Other languages
English (en)
Portuguese (pt)
Inventor
Anne Chantal Bechet
Riemke Van Dijkhuizen-Radersma
Martin Stigter
Jeroen Mattijs Bezemer
Original Assignee
Biolex Therapeutics Inc
Octoplus Polyactive Sciences B
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biolex Therapeutics Inc, Octoplus Polyactive Sciences B filed Critical Biolex Therapeutics Inc
Publication of PT1843749E publication Critical patent/PT1843749E/pt

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • A61K38/21Interferons [IFN]
    • A61K38/212IFN-alpha
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • A61K38/21Interferons [IFN]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1629Organic macromolecular compounds
    • A61K9/1641Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647Polyesters, e.g. poly(lactide-co-glycolide)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Communicable Diseases (AREA)
  • Immunology (AREA)
  • Inorganic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Dermatology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biotechnology (AREA)
  • AIDS & HIV (AREA)
  • Hematology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PT06700417T 2005-01-07 2006-01-06 Composições de libertação controlada para interferão à base de copolímeros de blocos de pegt/pbt PT1843749E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP05075043A EP1679065A1 (en) 2005-01-07 2005-01-07 Controlled release compositions for interferon based on PEGT/PBT block copolymers

Publications (1)

Publication Number Publication Date
PT1843749E true PT1843749E (pt) 2009-08-17

Family

ID=34937981

Family Applications (1)

Application Number Title Priority Date Filing Date
PT06700417T PT1843749E (pt) 2005-01-07 2006-01-06 Composições de libertação controlada para interferão à base de copolímeros de blocos de pegt/pbt

Country Status (24)

Country Link
US (3) US7736674B2 (sl)
EP (4) EP1679065A1 (sl)
JP (2) JP2008526837A (sl)
KR (2) KR20070118225A (sl)
CN (2) CN101791396A (sl)
AT (1) ATE431134T1 (sl)
AU (2) AU2006213168B2 (sl)
BR (1) BRPI0606514A2 (sl)
CA (1) CA2594434A1 (sl)
CY (1) CY1109297T1 (sl)
DE (1) DE602006006797D1 (sl)
DK (1) DK1843749T3 (sl)
ES (1) ES2327267T3 (sl)
HK (1) HK1152644A1 (sl)
HR (1) HRP20090434T1 (sl)
IL (2) IL184431A (sl)
MX (1) MX2007008293A (sl)
PL (1) PL1843749T3 (sl)
PT (1) PT1843749E (sl)
RS (1) RS51129B (sl)
RU (2) RU2409348C2 (sl)
SG (1) SG158856A1 (sl)
SI (1) SI1843749T1 (sl)
WO (1) WO2006085747A1 (sl)

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EP2055299A1 (en) 2007-10-23 2009-05-06 Koninklijke Philips Electronics N.V. Methods for preparing polymer microparticles
JP5733981B2 (ja) 2007-10-23 2015-06-10 コーニンクレッカ フィリップス エヌ ヴェ ポリマー微粒子を調製する方法及びデバイス
WO2010001325A2 (en) * 2008-06-30 2010-01-07 Silenseed Ltd Methods, compositions and systems for local delivery of drugs
EP2403537A1 (en) 2009-03-05 2012-01-11 Ascendis Pharma A/S Interferon alpha carrier prodrugs
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US8466159B2 (en) 2011-10-21 2013-06-18 Abbvie Inc. Methods for treating HCV
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Also Published As

Publication number Publication date
AU2010224413A1 (en) 2010-10-14
WO2006085747A1 (en) 2006-08-17
CY1109297T1 (el) 2014-07-02
US20080008733A1 (en) 2008-01-10
DK1843749T3 (da) 2009-09-07
SI1843749T1 (sl) 2009-10-31
EP2266535B1 (en) 2013-03-06
US20090226532A1 (en) 2009-09-10
IL184431A (en) 2012-03-29
CN101791396A (zh) 2010-08-04
US20100074868A1 (en) 2010-03-25
RU2010138739A (ru) 2012-03-27
JP2008526837A (ja) 2008-07-24
AU2006213168B2 (en) 2011-09-15
EP2266535A2 (en) 2010-12-29
EP2266535A3 (en) 2011-06-15
ES2327267T3 (es) 2009-10-27
KR20100109983A (ko) 2010-10-11
ATE431134T1 (de) 2009-05-15
BRPI0606514A2 (pt) 2010-01-19
RS51129B (sr) 2010-10-31
HK1152644A1 (en) 2012-03-09
PL1843749T3 (pl) 2009-10-30
JP2011016836A (ja) 2011-01-27
US7867518B2 (en) 2011-01-11
CN101137349B (zh) 2013-01-02
US8163307B2 (en) 2012-04-24
KR20070118225A (ko) 2007-12-14
US7736674B2 (en) 2010-06-15
RU2007130090A (ru) 2009-02-20
IL184431A0 (en) 2007-10-31
MX2007008293A (es) 2007-12-07
AU2010224413B2 (en) 2012-03-22
JP4887542B2 (ja) 2012-02-29
HRP20090434T1 (hr) 2009-09-30
EP1886668B1 (en) 2012-11-14
CA2594434A1 (en) 2006-08-17
CN101137349A (zh) 2008-03-05
IL208175A0 (en) 2010-12-30
KR101354521B1 (ko) 2014-01-22
RU2409348C2 (ru) 2011-01-20
EP1886668A1 (en) 2008-02-13
EP1843749A1 (en) 2007-10-17
SG158856A1 (en) 2010-02-26
DE602006006797D1 (de) 2009-06-25
EP1679065A1 (en) 2006-07-12
EP1843749B1 (en) 2009-05-13
AU2006213168A1 (en) 2006-08-17

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