DK1843749T3 - Sammens tninger med kontrolleret fris tning af interferon baseret p PEGT/PBT-blokcopolymerer - Google Patents

Sammens tninger med kontrolleret fris tning af interferon baseret p PEGT/PBT-blokcopolymerer

Info

Publication number
DK1843749T3
DK1843749T3 DK06700417T DK06700417T DK1843749T3 DK 1843749 T3 DK1843749 T3 DK 1843749T3 DK 06700417 T DK06700417 T DK 06700417T DK 06700417 T DK06700417 T DK 06700417T DK 1843749 T3 DK1843749 T3 DK 1843749T3
Authority
DK
Denmark
Prior art keywords
composition
pegt
controlled release
block copolymers
release compounds
Prior art date
Application number
DK06700417T
Other languages
Danish (da)
English (en)
Inventor
Anne Chantal Bechet
Dijkhuizen-Radersma Riemke Van
Martin Stigter
Jeroen Mattijs Bezemer
Original Assignee
Biolex Therapeutics Inc
Octoplus Polyactive Sciences B
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biolex Therapeutics Inc, Octoplus Polyactive Sciences B filed Critical Biolex Therapeutics Inc
Application granted granted Critical
Publication of DK1843749T3 publication Critical patent/DK1843749T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/21—Interferons [IFN]
    • A61K38/212—IFN-alpha
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/21—Interferons [IFN]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Virology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Oncology (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Communicable Diseases (AREA)
  • Inorganic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Dermatology (AREA)
  • Hematology (AREA)
  • AIDS & HIV (AREA)
  • Biotechnology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK06700417T 2005-01-07 2006-01-06 Sammens tninger med kontrolleret fris tning af interferon baseret p PEGT/PBT-blokcopolymerer DK1843749T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP05075043A EP1679065A1 (en) 2005-01-07 2005-01-07 Controlled release compositions for interferon based on PEGT/PBT block copolymers
PCT/NL2006/000006 WO2006085747A1 (en) 2005-01-07 2006-01-06 Controlled release compositions for interferon based on pegt/pbt block copolymers

Publications (1)

Publication Number Publication Date
DK1843749T3 true DK1843749T3 (da) 2009-09-07

Family

ID=34937981

Family Applications (1)

Application Number Title Priority Date Filing Date
DK06700417T DK1843749T3 (da) 2005-01-07 2006-01-06 Sammens tninger med kontrolleret fris tning af interferon baseret p PEGT/PBT-blokcopolymerer

Country Status (24)

Country Link
US (3) US7736674B2 (sl)
EP (4) EP1679065A1 (sl)
JP (2) JP2008526837A (sl)
KR (2) KR20070118225A (sl)
CN (2) CN101137349B (sl)
AT (1) ATE431134T1 (sl)
AU (2) AU2006213168B2 (sl)
BR (1) BRPI0606514A2 (sl)
CA (1) CA2594434A1 (sl)
CY (1) CY1109297T1 (sl)
DE (1) DE602006006797D1 (sl)
DK (1) DK1843749T3 (sl)
ES (1) ES2327267T3 (sl)
HK (1) HK1152644A1 (sl)
HR (1) HRP20090434T1 (sl)
IL (2) IL184431A (sl)
MX (1) MX2007008293A (sl)
PL (1) PL1843749T3 (sl)
PT (1) PT1843749E (sl)
RS (1) RS51129B (sl)
RU (2) RU2409348C2 (sl)
SG (1) SG158856A1 (sl)
SI (1) SI1843749T1 (sl)
WO (1) WO2006085747A1 (sl)

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CA2694440A1 (en) * 2007-07-25 2009-01-29 Biolex Therapeutics, Inc. Controlled release interferon drug products and treatment of hcv infection using same
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US8999945B2 (en) * 2008-06-30 2015-04-07 Silenseed Ltd Methods, compositions and systems for local delivery of drugs
EP2403537A1 (en) 2009-03-05 2012-01-11 Ascendis Pharma A/S Interferon alpha carrier prodrugs
JP6320912B2 (ja) * 2011-03-25 2018-05-09 セレクタ バイオサイエンシーズ インコーポレーテッドＳｅｌｅｃｔａ Ｂｉｏｓｃｉｅｎｃｅｓ，Ｉｎｃ． 浸透圧媒介性放出合成ナノ担体
US8492386B2 (en) 2011-10-21 2013-07-23 Abbvie Inc. Methods for treating HCV
SG2014011670A (en) 2011-10-21 2014-10-30 Abbvie Inc Combination treatment (eg. with abt-072 or abt -333) of daas for use in treating hcv
CN103826627B (zh) 2011-10-21 2016-02-24 艾伯维公司 包含至少两种直接抗病毒剂和利巴韦林的组合物在制备治疗hcv的药物中的用途
US8466159B2 (en) 2011-10-21 2013-06-18 Abbvie Inc. Methods for treating HCV
WO2016046817A1 (en) 2014-09-24 2016-03-31 Vital Beverages Global Inc. Compositions and methods for selective gi tract delivery
EA201892448A1 (ru) 2016-04-28 2019-06-28 Эмори Юниверсити Алкинсодержащие нуклеотидные и нуклеозидные терапевтические композиции и связанные с ними способы применения
CN114096234A (zh) 2019-07-12 2022-02-25 巴斯夫欧洲公司 生产载有挥发性有机活性物的微粒的方法

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Also Published As

Publication number Publication date
PL1843749T3 (pl) 2009-10-30
EP2266535B1 (en) 2013-03-06
ES2327267T3 (es) 2009-10-27
CN101791396A (zh) 2010-08-04
EP1886668A1 (en) 2008-02-13
IL184431A0 (en) 2007-10-31
JP4887542B2 (ja) 2012-02-29
EP1843749A1 (en) 2007-10-17
WO2006085747A1 (en) 2006-08-17
SI1843749T1 (sl) 2009-10-31
DE602006006797D1 (de) 2009-06-25
US7867518B2 (en) 2011-01-11
CY1109297T1 (el) 2014-07-02
PT1843749E (pt) 2009-08-17
KR20070118225A (ko) 2007-12-14
AU2006213168B2 (en) 2011-09-15
EP1843749B1 (en) 2009-05-13
AU2006213168A1 (en) 2006-08-17
JP2011016836A (ja) 2011-01-27
EP2266535A3 (en) 2011-06-15
EP2266535A2 (en) 2010-12-29
RU2409348C2 (ru) 2011-01-20
AU2010224413A1 (en) 2010-10-14
IL184431A (en) 2012-03-29
EP1679065A1 (en) 2006-07-12
CA2594434A1 (en) 2006-08-17
RS51129B (sr) 2010-10-31
US8163307B2 (en) 2012-04-24
AU2010224413B2 (en) 2012-03-22
US20080008733A1 (en) 2008-01-10
US20100074868A1 (en) 2010-03-25
US20090226532A1 (en) 2009-09-10
MX2007008293A (es) 2007-12-07
ATE431134T1 (de) 2009-05-15
RU2010138739A (ru) 2012-03-27
EP1886668B1 (en) 2012-11-14
JP2008526837A (ja) 2008-07-24
HK1152644A1 (en) 2012-03-09
HRP20090434T1 (hr) 2009-09-30
CN101137349A (zh) 2008-03-05
RU2007130090A (ru) 2009-02-20
KR20100109983A (ko) 2010-10-11
CN101137349B (zh) 2013-01-02
BRPI0606514A2 (pt) 2010-01-19
US7736674B2 (en) 2010-06-15
IL208175A0 (en) 2010-12-30
SG158856A1 (en) 2010-02-26
KR101354521B1 (ko) 2014-01-22

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