PT1824504E - Combinações antitumorais contendo vegf-trap e 5fu ou um de seus derivados - Google Patents
Combinações antitumorais contendo vegf-trap e 5fu ou um de seus derivados Download PDFInfo
- Publication number
- PT1824504E PT1824504E PT05824581T PT05824581T PT1824504E PT 1824504 E PT1824504 E PT 1824504E PT 05824581 T PT05824581 T PT 05824581T PT 05824581 T PT05824581 T PT 05824581T PT 1824504 E PT1824504 E PT 1824504E
- Authority
- PT
- Portugal
- Prior art keywords
- trap
- derivatives
- combinations containing
- containing vegf
- antitumor combinations
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/525—Isoalloxazines, e.g. riboflavins, vitamin B2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
- A61K38/179—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Cell Biology (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0412870A FR2878749B1 (fr) | 2004-12-03 | 2004-12-03 | Combinaisons antitumorales contenant en agent inhibiteur de vegt et du 5fu ou un de ses derives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT1824504E true PT1824504E (pt) | 2009-06-25 |
Family
ID=34954452
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT05824581T PT1824504E (pt) | 2004-12-03 | 2005-12-02 | Combinações antitumorais contendo vegf-trap e 5fu ou um de seus derivados |
Country Status (26)
| Country | Link |
|---|---|
| US (3) | US20060178305A1 (pt) |
| EP (1) | EP1824504B1 (pt) |
| JP (1) | JP4980236B2 (pt) |
| KR (1) | KR101313404B1 (pt) |
| CN (1) | CN101068564B (pt) |
| AT (1) | ATE426409T1 (pt) |
| AU (1) | AU2005311191C1 (pt) |
| BR (1) | BRPI0518700B8 (pt) |
| CA (1) | CA2586735C (pt) |
| CY (3) | CY1109181T1 (pt) |
| DE (1) | DE602005013568D1 (pt) |
| DK (1) | DK1824504T3 (pt) |
| ES (1) | ES2324233T3 (pt) |
| FR (1) | FR2878749B1 (pt) |
| HK (1) | HK1114769A1 (pt) |
| HR (1) | HRP20090336T1 (pt) |
| IL (1) | IL183481A (pt) |
| LU (2) | LU92203I2 (pt) |
| ME (1) | ME01706B (pt) |
| MX (1) | MX2007006607A (pt) |
| PL (1) | PL1824504T3 (pt) |
| PT (1) | PT1824504E (pt) |
| RS (1) | RS50769B (pt) |
| RU (1) | RU2384344C2 (pt) |
| SI (1) | SI1824504T1 (pt) |
| WO (1) | WO2006059012A1 (pt) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2918279B1 (fr) * | 2007-07-05 | 2010-10-22 | Aventis Pharma Sa | Combinaisons antitumorales contenant un agent inhibiteur de vegf et de l'irinotecan |
| JO3283B1 (ar) | 2011-04-26 | 2018-09-16 | Sanofi Sa | تركيب يتضمن أفليبيرسيبت, حمض فولينيك, 5- فلورويوراسيل (5- Fu) وإرينوسيتان (FOLFIRI) |
| US9840553B2 (en) | 2014-06-28 | 2017-12-12 | Kodiak Sciences Inc. | Dual PDGF/VEGF antagonists |
| EP3170005B1 (en) | 2014-07-18 | 2019-04-10 | Sanofi | Method for predicting the outcome of a treatment with aflibercept of a patient suspected to suffer from a cancer |
| IL290457B1 (en) | 2015-12-30 | 2024-10-01 | Kodiak Sciences Inc | Antibodies and their conjugates |
| EP3246029A1 (en) * | 2016-05-19 | 2017-11-22 | Boehringer Ingelheim International Gmbh | Pharmaceutical combination of nintedanib and capecitabine for the treatment of colorectal cancer |
| MX2020009152A (es) | 2018-03-02 | 2020-11-09 | Kodiak Sciences Inc | Anticuerpos de il-6 y constructos de fusion y conjugados de los mismos. |
| CA3157509A1 (en) | 2019-10-10 | 2021-04-15 | Kodiak Sciences Inc. | Methods of treating an eye disorder |
| CN115197948A (zh) * | 2021-04-13 | 2022-10-18 | 江苏康缘瑞翱生物医药科技有限公司 | 一种重组新城疫病毒rNDV-VEGF-Trap、其基因组、制备方法及其用途 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7087411B2 (en) * | 1999-06-08 | 2006-08-08 | Regeneron Pharmaceuticals, Inc. | Fusion protein capable of binding VEGF |
| JP4723140B2 (ja) * | 1999-06-08 | 2011-07-13 | リジェネロン・ファーマシューティカルズ・インコーポレイテッド | 改善された薬物動態特性を有する改変キメラポリペプチド |
| AR046510A1 (es) * | 2003-07-25 | 2005-12-14 | Regeneron Pharma | Composicion de un antagonista de vegf y un agente anti-proliferativo |
-
2004
- 2004-12-03 FR FR0412870A patent/FR2878749B1/fr active Active
-
2005
- 2005-12-02 ME MEP-2009-272A patent/ME01706B/me unknown
- 2005-12-02 CN CN2005800416406A patent/CN101068564B/zh active Active
- 2005-12-02 CA CA2586735A patent/CA2586735C/fr active Active
- 2005-12-02 US US11/293,761 patent/US20060178305A1/en not_active Abandoned
- 2005-12-02 KR KR1020077012431A patent/KR101313404B1/ko active IP Right Grant
- 2005-12-02 DK DK05824581T patent/DK1824504T3/da active
- 2005-12-02 SI SI200530696T patent/SI1824504T1/sl unknown
- 2005-12-02 RS RSP-2009/0272A patent/RS50769B/sr unknown
- 2005-12-02 PL PL05824581T patent/PL1824504T3/pl unknown
- 2005-12-02 EP EP05824581A patent/EP1824504B1/fr active Active
- 2005-12-02 AU AU2005311191A patent/AU2005311191C1/en active Active
- 2005-12-02 AT AT05824581T patent/ATE426409T1/de active
- 2005-12-02 MX MX2007006607A patent/MX2007006607A/es active IP Right Grant
- 2005-12-02 BR BRPI0518700A patent/BRPI0518700B8/pt active IP Right Grant
- 2005-12-02 JP JP2007543885A patent/JP4980236B2/ja active Active
- 2005-12-02 RU RU2007123607/15A patent/RU2384344C2/ru active Protection Beyond IP Right Term
- 2005-12-02 DE DE602005013568T patent/DE602005013568D1/de active Active
- 2005-12-02 WO PCT/FR2005/003005 patent/WO2006059012A1/fr active Application Filing
- 2005-12-02 PT PT05824581T patent/PT1824504E/pt unknown
- 2005-12-02 ES ES05824581T patent/ES2324233T3/es active Active
-
2007
- 2007-05-28 IL IL183481A patent/IL183481A/en active IP Right Grant
-
2008
- 2008-04-28 HK HK08104697.0A patent/HK1114769A1/xx unknown
-
2009
- 2009-06-12 HR HR20090336T patent/HRP20090336T1/xx unknown
- 2009-06-25 CY CY20091100671T patent/CY1109181T1/el unknown
- 2009-07-24 US US12/508,834 patent/US8388963B2/en active Active
-
2013
- 2013-03-04 US US13/783,919 patent/US20130184205A1/en not_active Abandoned
- 2013-05-13 CY CY2013017C patent/CY2013017I1/el unknown
- 2013-05-13 CY CY2013018C patent/CY2013018I1/el unknown
- 2013-05-15 LU LU92203C patent/LU92203I2/fr unknown
- 2013-05-15 LU LU92202C patent/LU92202I2/fr unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| LU92203I9 (pt) | ||
| GEP20125691B (en) | Compounds and compositions as protein kinase inhibitors | |
| CY1116156T1 (el) | Παραγωγα πυριμιδινης συνδεδεμενα με οξυγονο | |
| MX2009006704A (es) | Derivados de amina triciclicos como inhibidores de proteina de tirosina cinasa. | |
| MY143407A (en) | Indazole derivatives as inhibitors of hormone sensitive lipase | |
| NO20065368L (no) | Terapeutiske blandinger inneholdende minst et pyrrolobenzodiazepinderivat og fludarabin | |
| TW200728285A (en) | Diacylindazole derivatives as inhibitors of lipases and phospholipases | |
| CL2008003798A1 (es) | Compuestos derivados de heterobiciclos aromaticos sustituidos, inhibidores de pi3 quinasa; composicion farmaceutica; utiles en el tratamiento de cancer, melanomas, glioblastomas, entre otras enfermedades. | |
| DOP2002000438A (es) | Inhibidores de la dipetidil peptidasa beta-amino heterocíclica para el tratamiento o la prevención de la diabetes | |
| ATE432281T1 (de) | Pyrrolotriazin-kinasehemmer | |
| TW200716091A (en) | New therapeutic combinations for the treatment or prevention of psychotic disorders | |
| MX2010006206A (es) | Derivados de oxindol substituidos por 5-halogeno y el uso de los mismos para el tratamiento de enfermedades dependientes de la vasopresina. | |
| GB0226434D0 (en) | Combination product | |
| CL2008000021A1 (es) | Compuestos derivados de 2,4-dianilinopirimidinas, inhibidores de proteinas cinasas; procedimiento de preparacion; composicion farmaceutica; y uso para el tratamiento o prevencion de enfermedades inflamatorias, diabetes y cancer. | |
| CY1111762T1 (el) | Διενυδρη παμοϊκη ολανζαπiνη | |
| EA200970353A1 (ru) | Комбинированное лекарственное средство | |
| TW200716561A (en) | P38 inhibitors and methods of use thereof | |
| WO2006128740A3 (en) | Anti-vascular methods and therapies employing lysyl oxidase inhibitors | |
| SE0300457D0 (sv) | Novel compounds | |
| EA200971103A1 (ru) | Иммуноцитокины для лечения рака в сочетании с химиотерапевтическими агентами | |
| BRPI0507985A (pt) | derivados de piperazina uréia para o tratamento de endometriose | |
| WO2007012967A3 (en) | Combination of voriconazole and fluconazole | |
| BRPI0419229A (pt) | derivados de tiofenopirimidinona substituìdos como inibidores de 17beta-hidroxiesteróide-desidrogenase, uso e composição farmacêutica | |
| UA95260C2 (ru) | Производное 4-(3-аминопиразол)пиримидина и его применение для лечения злокачественного новообразования |