WO2007012967A3 - Combination of voriconazole and fluconazole - Google Patents

Combination of voriconazole and fluconazole Download PDF

Info

Publication number
WO2007012967A3
WO2007012967A3 PCT/IB2006/002148 IB2006002148W WO2007012967A3 WO 2007012967 A3 WO2007012967 A3 WO 2007012967A3 IB 2006002148 W IB2006002148 W IB 2006002148W WO 2007012967 A3 WO2007012967 A3 WO 2007012967A3
Authority
WO
WIPO (PCT)
Prior art keywords
voriconazole
fluconazole
combination
kits
treatment
Prior art date
Application number
PCT/IB2006/002148
Other languages
French (fr)
Other versions
WO2007012967A2 (en
Inventor
Michael John Humphrey
Original Assignee
Pfizer Ltd
Michael John Humphrey
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Ltd, Michael John Humphrey filed Critical Pfizer Ltd
Publication of WO2007012967A2 publication Critical patent/WO2007012967A2/en
Publication of WO2007012967A3 publication Critical patent/WO2007012967A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4196—1,2,4-Triazoles

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The invention provides a therapeutic combination comprising voriconazole and fluconazole in a 1:1 or 2:1 weight ratio. Pharmaceutical compositions, unit dosage forms and kits comprising voriconazole and fluconazole, and their use in the treatment of fungal infections, are also provided.
PCT/IB2006/002148 2005-07-27 2006-07-21 Combination of voriconazole and fluconazole WO2007012967A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US70317605P 2005-07-27 2005-07-27
US60/703,176 2005-07-27

Publications (2)

Publication Number Publication Date
WO2007012967A2 WO2007012967A2 (en) 2007-02-01
WO2007012967A3 true WO2007012967A3 (en) 2007-04-12

Family

ID=37663768

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2006/002148 WO2007012967A2 (en) 2005-07-27 2006-07-21 Combination of voriconazole and fluconazole

Country Status (1)

Country Link
WO (1) WO2007012967A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010084505A2 (en) * 2008-06-06 2010-07-29 Glenmark Pharmaceuticals Limited Stable topical formulation comprising voriconazole

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005084671A2 (en) * 2004-02-04 2005-09-15 Pfizer Limited Combination of voriconazole and an antifungal cyp2c19 inhibitor

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005084671A2 (en) * 2004-02-04 2005-09-15 Pfizer Limited Combination of voriconazole and an antifungal cyp2c19 inhibitor

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
GHANNOUM M ET AL: "IN VITRO EVALUATION OF VORICONAZOLE IN COMBINATION WITH ANTIFUNGALS", INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES, INTERNATIONAL SOCIETY FOR INFECTIOUS DISEASES, HAMILTON, CA, vol. 6, no. SUPPL 2, June 2002 (2002-06-01), pages 2S50 - 2S51, XP008058584, ISSN: 1201-9712 *

Also Published As

Publication number Publication date
WO2007012967A2 (en) 2007-02-01

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