CY2013018I1 - Αντικαρκινικοι συνδυασμοι που περιεχουν vegf-trap και 5fu ή ενα εκ των παραγωγων αυτων. - Google Patents

Αντικαρκινικοι συνδυασμοι που περιεχουν vegf-trap και 5fu ή ενα εκ των παραγωγων αυτων.

Info

Publication number
CY2013018I1
CY2013018I1 CY2013018C CY2013018C CY2013018I1 CY 2013018 I1 CY2013018 I1 CY 2013018I1 CY 2013018 C CY2013018 C CY 2013018C CY 2013018 C CY2013018 C CY 2013018C CY 2013018 I1 CY2013018 I1 CY 2013018I1
Authority
CY
Cyprus
Prior art keywords
trap
derivatives
combinations containing
containing vegf
cancer combinations
Prior art date
Application number
CY2013018C
Other languages
English (en)
Original Assignee
Aventis Pharma S.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34954452&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CY2013018(I1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Aventis Pharma S.A. filed Critical Aventis Pharma S.A.
Publication of CY2013018I1 publication Critical patent/CY2013018I1/el

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/513Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/525Isoalloxazines, e.g. riboflavins, vitamin B2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7068Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177Receptors; Cell surface antigens; Cell surface determinants
    • A61K38/179Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18Growth factors; Growth regulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Cell Biology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CY2013018C 2004-12-03 2013-05-13 Αντικαρκινικοι συνδυασμοι που περιεχουν vegf-trap και 5fu ή ενα εκ των παραγωγων αυτων. CY2013018I1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0412870A FR2878749B1 (fr) 2004-12-03 2004-12-03 Combinaisons antitumorales contenant en agent inhibiteur de vegt et du 5fu ou un de ses derives
PCT/FR2005/003005 WO2006059012A1 (fr) 2004-12-03 2005-12-02 Combinaisons antitumorales contenant un agent inhibiteur de vegf et du 5fu ou un de ses derives

Publications (1)

Publication Number Publication Date
CY2013018I1 true CY2013018I1 (el) 2020-05-29

Family

ID=34954452

Family Applications (3)

Application Number Title Priority Date Filing Date
CY20091100671T CY1109181T1 (el) 2004-12-03 2009-06-25 Αντικαρκινικοι συνδυασμοι που περιεχουν vegf-trap και 5fu ή ενα εκ των παραγωγων αυτων.
CY2013017C CY2013017I1 (el) 2004-12-03 2013-05-13 Αντικαρκινικοι συνδυασμοι που περιεχουν vegf-trap και 5fu ή ενα εκ των παραγωγων αυτων.
CY2013018C CY2013018I1 (el) 2004-12-03 2013-05-13 Αντικαρκινικοι συνδυασμοι που περιεχουν vegf-trap και 5fu ή ενα εκ των παραγωγων αυτων.

Family Applications Before (2)

Application Number Title Priority Date Filing Date
CY20091100671T CY1109181T1 (el) 2004-12-03 2009-06-25 Αντικαρκινικοι συνδυασμοι που περιεχουν vegf-trap και 5fu ή ενα εκ των παραγωγων αυτων.
CY2013017C CY2013017I1 (el) 2004-12-03 2013-05-13 Αντικαρκινικοι συνδυασμοι που περιεχουν vegf-trap και 5fu ή ενα εκ των παραγωγων αυτων.

Country Status (26)

Country Link
US (3) US20060178305A1 (el)
EP (1) EP1824504B1 (el)
JP (1) JP4980236B2 (el)
KR (1) KR101313404B1 (el)
CN (1) CN101068564B (el)
AT (1) ATE426409T1 (el)
AU (1) AU2005311191C1 (el)
BR (1) BRPI0518700B8 (el)
CA (1) CA2586735C (el)
CY (3) CY1109181T1 (el)
DE (1) DE602005013568D1 (el)
DK (1) DK1824504T3 (el)
ES (1) ES2324233T3 (el)
FR (1) FR2878749B1 (el)
HK (1) HK1114769A1 (el)
HR (1) HRP20090336T1 (el)
IL (1) IL183481A (el)
LU (2) LU92203I2 (el)
ME (1) ME01706B (el)
MX (1) MX2007006607A (el)
PL (1) PL1824504T3 (el)
PT (1) PT1824504E (el)
RS (1) RS50769B (el)
RU (1) RU2384344C2 (el)
SI (1) SI1824504T1 (el)
WO (1) WO2006059012A1 (el)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2918279B1 (fr) * 2007-07-05 2010-10-22 Aventis Pharma Sa Combinaisons antitumorales contenant un agent inhibiteur de vegf et de l'irinotecan
JO3283B1 (ar) 2011-04-26 2018-09-16 Sanofi Sa تركيب يتضمن أفليبيرسيبت, حمض فولينيك, 5- فلورويوراسيل (5- Fu) وإرينوسيتان (FOLFIRI)
US9840553B2 (en) 2014-06-28 2017-12-12 Kodiak Sciences Inc. Dual PDGF/VEGF antagonists
EP3170005B1 (en) 2014-07-18 2019-04-10 Sanofi Method for predicting the outcome of a treatment with aflibercept of a patient suspected to suffer from a cancer
IL290457B1 (en) 2015-12-30 2024-10-01 Kodiak Sciences Inc Antibodies and their conjugates
EP3246029A1 (en) * 2016-05-19 2017-11-22 Boehringer Ingelheim International Gmbh Pharmaceutical combination of nintedanib and capecitabine for the treatment of colorectal cancer
MX2020009152A (es) 2018-03-02 2020-11-09 Kodiak Sciences Inc Anticuerpos de il-6 y constructos de fusion y conjugados de los mismos.
CA3157509A1 (en) 2019-10-10 2021-04-15 Kodiak Sciences Inc. Methods of treating an eye disorder
CN115197948A (zh) * 2021-04-13 2022-10-18 江苏康缘瑞翱生物医药科技有限公司 一种重组新城疫病毒rNDV-VEGF-Trap、其基因组、制备方法及其用途

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7087411B2 (en) * 1999-06-08 2006-08-08 Regeneron Pharmaceuticals, Inc. Fusion protein capable of binding VEGF
JP4723140B2 (ja) * 1999-06-08 2011-07-13 リジェネロン・ファーマシューティカルズ・インコーポレイテッド 改善された薬物動態特性を有する改変キメラポリペプチド
AR046510A1 (es) * 2003-07-25 2005-12-14 Regeneron Pharma Composicion de un antagonista de vegf y un agente anti-proliferativo

Also Published As

Publication number Publication date
ES2324233T3 (es) 2009-08-03
CA2586735C (fr) 2014-08-12
SI1824504T1 (sl) 2009-08-31
JP4980236B2 (ja) 2012-07-18
CN101068564A (zh) 2007-11-07
IL183481A0 (en) 2007-09-20
FR2878749A1 (fr) 2006-06-09
RU2384344C2 (ru) 2010-03-20
LU92203I2 (fr) 2013-11-15
LU92202I9 (el) 2019-01-15
CY2013017I1 (el) 2014-07-02
BRPI0518700B8 (pt) 2021-05-25
RU2007123607A (ru) 2009-01-10
DE602005013568D1 (de) 2009-05-07
KR20070091130A (ko) 2007-09-07
ATE426409T1 (de) 2009-04-15
AU2005311191A1 (en) 2006-06-08
AU2005311191B2 (en) 2011-12-08
WO2006059012A1 (fr) 2006-06-08
AU2005311191C1 (en) 2015-04-30
CA2586735A1 (fr) 2006-06-08
PT1824504E (pt) 2009-06-25
BRPI0518700B1 (pt) 2020-02-11
LU92203I9 (el) 2019-01-15
HRP20090336T1 (en) 2009-07-31
BRPI0518700A2 (pt) 2008-12-02
DK1824504T3 (da) 2009-07-20
CN101068564B (zh) 2010-12-15
RS50769B (sr) 2010-08-31
LU92202I2 (fr) 2013-11-15
PL1824504T3 (pl) 2009-08-31
HK1114769A1 (en) 2008-11-14
KR101313404B1 (ko) 2013-10-01
CY1109181T1 (el) 2014-07-02
FR2878749B1 (fr) 2007-12-21
JP2008521866A (ja) 2008-06-26
US8388963B2 (en) 2013-03-05
EP1824504A1 (fr) 2007-08-29
MX2007006607A (es) 2007-07-25
EP1824504B1 (fr) 2009-03-25
US20060178305A1 (en) 2006-08-10
ME01706B (me) 2010-08-31
US20130184205A1 (en) 2013-07-18
US20090285841A1 (en) 2009-11-19
IL183481A (en) 2013-09-30

Similar Documents

Publication Publication Date Title
CY2013018I1 (el) Αντικαρκινικοι συνδυασμοι που περιεχουν vegf-trap και 5fu ή ενα εκ των παραγωγων αυτων.
CY1118082T1 (el) Ανταγωνιστες μουσκαρινικου υποδοχεα ακετυλοχολινης
CY2017006I2 (el) Αερολυμενες φθοροκινολονες και χρησεις αυτων
CY1121162T1 (el) M-csf-ειδικο μονοκλωνικο αντισωμα και χρησεις αυτου
CY2017029I2 (el) ΑΝΤΙΚΑΡΚΙΝΙΚΟ ΦΑΡΜΑΚΟ ΠΟΥ ΠΕΡΙΕΧΕΙ α,α,α-ΤΡΙΦΘΟΡΟΘΥΜΙΔΙΝΗ ΚΑΙ ΑΝΑΣΤΟΛΕΑ ΦΩΣΦΟΡΥΛΑΣΗΣ ΘΥΜΙΔΙΝΗΣ
CY1111364T1 (el) Ανταγωνιστες μουσκαρινικου υποδοχεα ακετυλοχολινης
DE602005016849D1 (de) Substituierte Morpholin and Thiomorpholin Derivate
DE602005027546D1 (de) Aryl- und heteroarylpiperidincarboxylatderivate, deren herstellung und deren verwendung in form von faah-enzyminhibitoren
CY1114574T1 (el) Παραγωγα πιπεριδινης και πιπεραζινης για τη θεραπεια ογκων
BRPI0814267A2 (pt) Agentes citotóxicos compreendendo novos derivados de tomaicmicina e o seu uso terapêutico.
MA28489B1 (fr) Preparations pharmaceutiques
DK1812895T3 (da) Stofkilde
DE602005022116D1 (de) 5-heteroarylthiazole und deren verwendung als pi3k-inhibitoren
DK1742659T3 (da) Mikrofluidiserede olie-i-vand-emulsioner og vaccinesammensætninger
DE502005009598D1 (de) Partikelstabilisierte emulsionen
CY1109054T1 (el) Ρρυ αγωνιστες και χρησεις αυτων
CY1110026T1 (el) Ενωσεις πιπεραζινης βενζισοξαζολης και μεθοδοι χρησης εξ αυτων
NL1030060A1 (nl) Fischer-Tropsch-wassamenstelling en wijze van transport.
CY1120206T1 (el) Μεθοδοι για τη συγκλινουσα συνθεση παραγωγων καλιχεαμικινης
UY29872A1 (es) Derivados de carbamoilbenzotriazol como inhibidores de lipasas y fosfolipasas
CY2018021I1 (el) Αντισωμα anti-fgf23 και φαρμακευτικη συνθεση που το περιλαμβανει
UY30087A1 (es) Piperazinas y piperidinas como potenciadoras de mglur5
ITRM20050589A1 (it) Accessorio da tavolo per il supporto di borse e simili.
CY1111983T1 (el) Φαρμακευτικη συνθεση και μεθοδος χρησης αντιμυκητιακου παραγοντα σε συνδυασμο
DE602005005211D1 (de) Neue azaindol-thiazolinone als krebsmittel