PT1632232E - Sal de 4-[[4-[[4-(2-cianoetenil)-2,6-dimetilfenil]amino]- 2-pirimidinil]amino]benzonitrilo - Google Patents
Sal de 4-[[4-[[4-(2-cianoetenil)-2,6-dimetilfenil]amino]- 2-pirimidinil]amino]benzonitrilo Download PDFInfo
- Publication number
- PT1632232E PT1632232E PT05108086T PT05108086T PT1632232E PT 1632232 E PT1632232 E PT 1632232E PT 05108086 T PT05108086 T PT 05108086T PT 05108086 T PT05108086 T PT 05108086T PT 1632232 E PT1632232 E PT 1632232E
- Authority
- PT
- Portugal
- Prior art keywords
- amino
- dimethylphenyl
- pyrimidinyl
- cyanooethenyl
- benzonitryl
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Virology (AREA)
- Molecular Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- AIDS & HIV (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Tropical Medicine & Parasitology (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
- Hybrid Cells (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| MYPI20043578A MY169670A (en) | 2003-09-03 | 2004-09-02 | Combinations of a pyrimidine containing nnrti with rt inhibitors |
| PCT/EP2004/052028 WO2005021001A1 (en) | 2003-09-03 | 2004-09-03 | Combinations of a pyrimidine containing nnrti with rt inhibitors |
| EP05101467 | 2005-02-25 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT1632232E true PT1632232E (pt) | 2011-08-02 |
Family
ID=38091637
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT05108086T PT1632232E (pt) | 2004-09-02 | 2005-09-02 | Sal de 4-[[4-[[4-(2-cianoetenil)-2,6-dimetilfenil]amino]- 2-pirimidinil]amino]benzonitrilo |
Country Status (23)
| Country | Link |
|---|---|
| EP (1) | EP1632232B3 (https=) |
| JP (1) | JP4912309B2 (https=) |
| KR (1) | KR101284361B1 (https=) |
| CN (1) | CN104586850A (https=) |
| AT (1) | ATE508748T1 (https=) |
| BR (1) | BRPI0514871A (https=) |
| CY (3) | CY1112249T1 (https=) |
| DK (1) | DK1632232T6 (https=) |
| EA (1) | EA013686B1 (https=) |
| ES (1) | ES2371442T7 (https=) |
| FR (2) | FR16C1023I2 (https=) |
| HK (1) | HK1210029A1 (https=) |
| HU (2) | HUS1600061I1 (https=) |
| IL (1) | IL181650A (https=) |
| LT (2) | LTC1632232I2 (https=) |
| ME (1) | ME01246B (https=) |
| MX (1) | MX2007002595A (https=) |
| NI (1) | NI200700068A (https=) |
| NO (3) | NO340654B1 (https=) |
| PL (1) | PL1632232T6 (https=) |
| PT (1) | PT1632232E (https=) |
| RS (1) | RS51923B2 (https=) |
| SI (1) | SI1632232T1 (https=) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MY169670A (en) | 2003-09-03 | 2019-05-08 | Tibotec Pharm Ltd | Combinations of a pyrimidine containing nnrti with rt inhibitors |
| PT1981506E (pt) * | 2006-01-20 | 2013-06-25 | Janssen R & D Ireland | Tratamento a longo prazo da infeção pelo vih com tmc278 |
| AR065720A1 (es) | 2007-03-14 | 2009-06-24 | Tibotec Pharm Ltd | Polvos para reconstitucion que comprenden rilpivirina dispersos en ciertos polimeros. uso. proceso. |
| JP2014500261A (ja) * | 2010-11-19 | 2014-01-09 | ギリアード サイエンシーズ， インコーポレイテッド | リルピビリンＨＣｌおよびフマル酸テノホビルジソプロキシルを含有する治療用組成物 |
| KR101879468B1 (ko) * | 2011-04-15 | 2018-07-17 | 엠큐어 파마슈티컬즈 리미티드 | 릴피비린 중간체의 제조를 위한 공정 |
| EP2604593A1 (en) | 2011-12-14 | 2013-06-19 | Sandoz AG | Polymorph of Rilpivirine hydrochloride and its use as antiviral |
| WO2013087794A1 (en) | 2011-12-14 | 2013-06-20 | Sandoz Ag | Polymorph of rilpivirine hydrochloride and its use as antiviral |
| EP2628732A1 (en) | 2012-02-20 | 2013-08-21 | Sandoz AG | Novel crystalline form of rilpivirine hydrochloride |
| WO2013153162A1 (en) | 2012-04-11 | 2013-10-17 | Sandoz Ag | Polymorph of rilpivirine hydrochloride |
| WO2013153161A2 (en) | 2012-04-11 | 2013-10-17 | Sandoz Ag | Novel polymorph of rilpivirine hydrochloride |
| CN103570688B (zh) * | 2012-07-19 | 2016-06-08 | 中国科学院上海药物研究所 | 2，5-二氨甲基吡嗪类化合物、其药物组合物、制备方法和用途 |
| GR1008965B (el) * | 2015-12-02 | 2017-02-28 | Φαρματεν Ανωνυμος Βιομηχανικη Και Εμπορικη Εταιρεια Φαρμακευτικων Ιατρικων Και Καλλυντικων Προϊοντων | Φαρμακευτικο σκευασμα που περιλαμβανει δαρουναβιρη και μεθοδος παρασκευης αυτου |
| RU2616267C1 (ru) * | 2016-01-25 | 2017-04-13 | Закрытое Акционерное Общество "БИОКОМ" | Твердая лекарственная форма индинавира немедленного высвобождения и способ ее получения |
| US11065198B2 (en) * | 2016-10-24 | 2021-07-20 | Janssen Sciences Ireland Unlimited Company | Dispersible compositions |
| CN110958883A (zh) * | 2017-06-30 | 2020-04-03 | Viiv保健公司 | 组合及其用途和疗法 |
| CN114392241B (zh) * | 2022-01-10 | 2023-07-25 | 安徽贝克生物制药有限公司 | 一种利匹韦林片及其制备方法 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6307543B1 (en) * | 1998-09-10 | 2001-10-23 | Silicon Image, Inc. | Bi-directional data transfer using two pair of differential lines as a single additional differential pair |
| MY169670A (en) * | 2003-09-03 | 2019-05-08 | Tibotec Pharm Ltd | Combinations of a pyrimidine containing nnrti with rt inhibitors |
| JO3429B1 (ar) * | 2001-08-13 | 2019-10-20 | Janssen Pharmaceutica Nv | مشتقات برميدينات مثبطة فيروس الايدز |
| DK1529032T3 (da) * | 2002-08-09 | 2013-07-08 | Janssen Pharmaceutica Nv | Fremgangsmåder til fremstilling af 4-4-4-(2-cyanoethenyl)-2,6-dimethylphenyl)amino)-2-pyrimidinyl)aminobenzonitrill |
| WO2004050068A1 (en) * | 2002-11-29 | 2004-06-17 | Janssen Pharmaceutica N.V. | Pharmaceutical compositions comprising a basic respectively acidic drug compound, a surfactant and a physiologically tolerable water-soluble acid respectively base |
| BRPI0407329A (pt) * | 2003-02-07 | 2006-01-10 | Janssen Pharmaceutica Nv | Derivados de pirimidina para a prevenção de infecção de hiv |
-
2005
- 2005-09-02 BR BRPI0514871-5A patent/BRPI0514871A/pt not_active Application Discontinuation
- 2005-09-02 RS RS20110355A patent/RS51923B2/sr unknown
- 2005-09-02 EP EP05108086.9A patent/EP1632232B3/en not_active Expired - Lifetime
- 2005-09-02 JP JP2007528886A patent/JP4912309B2/ja not_active Expired - Lifetime
- 2005-09-02 SI SI200531339T patent/SI1632232T1/sl unknown
- 2005-09-02 ES ES05108086T patent/ES2371442T7/es active Active
- 2005-09-02 DK DK05108086.9T patent/DK1632232T6/da active
- 2005-09-02 PT PT05108086T patent/PT1632232E/pt unknown
- 2005-09-02 AT AT05108086T patent/ATE508748T1/de active
- 2005-09-02 CN CN201510012919.7A patent/CN104586850A/zh active Pending
- 2005-09-02 EA EA200700536A patent/EA013686B1/ru active Protection Beyond IP Right Term
- 2005-09-02 MX MX2007002595A patent/MX2007002595A/es active IP Right Grant
- 2005-09-02 ME MEP-2011-144A patent/ME01246B/me unknown
- 2005-09-02 PL PL05108086T patent/PL1632232T6/pl unknown
- 2005-09-02 KR KR1020077006837A patent/KR101284361B1/ko not_active Expired - Lifetime
-
2007
- 2007-03-01 NI NI200700068A patent/NI200700068A/es unknown
- 2007-03-01 IL IL181650A patent/IL181650A/en active IP Right Grant
- 2007-04-02 NO NO20071745A patent/NO340654B1/no active Protection Beyond IP Right Term
-
2011
- 2011-08-10 CY CY20111100775T patent/CY1112249T1/el unknown
-
2015
- 2015-11-03 HK HK15110805.7A patent/HK1210029A1/xx unknown
-
2016
- 2016-12-20 HU HUS1600061C patent/HUS1600061I1/hu unknown
- 2016-12-20 HU HUS1600060C patent/HUS1600060I1/hu unknown
- 2016-12-20 FR FR16C1023C patent/FR16C1023I2/fr active Active
- 2016-12-20 LT LTPA2016042C patent/LTC1632232I2/lt unknown
- 2016-12-20 LT LTPA2016043C patent/LTPA2016043I1/lt unknown
- 2016-12-20 FR FR16C1025C patent/FR16C1025I2/fr active Active
- 2016-12-20 CY CY2016051C patent/CY2016051I1/el unknown
- 2016-12-20 CY CY2016050C patent/CY2016050I1/el unknown
-
2017
- 2017-11-21 NO NO2017065C patent/NO2017065I1/no unknown
- 2017-11-21 NO NO2017063C patent/NO2017063I1/no unknown
Also Published As
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