PT1565451E - Derivados do ácido halotenoil-ciclopropano-1-carboxílico. - Google Patents
Derivados do ácido halotenoil-ciclopropano-1-carboxílico. Download PDFInfo
- Publication number
- PT1565451E PT1565451E PT03811772T PT03811772T PT1565451E PT 1565451 E PT1565451 E PT 1565451E PT 03811772 T PT03811772 T PT 03811772T PT 03811772 T PT03811772 T PT 03811772T PT 1565451 E PT1565451 E PT 1565451E
- Authority
- PT
- Portugal
- Prior art keywords
- cyclopropane
- thenoyl
- chloro
- carboxylate
- compounds
- Prior art date
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- 150000001875 compounds Chemical class 0.000 claims abstract description 73
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- 125000004178 (C1-C4) alkyl group Chemical group 0.000 claims abstract description 6
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- 229920003109 sodium starch glycolate Polymers 0.000 description 1
- 229940079832 sodium starch glycolate Drugs 0.000 description 1
- 239000008109 sodium starch glycolate Substances 0.000 description 1
- HPALAKNZSZLMCH-UHFFFAOYSA-M sodium;chloride;hydrate Chemical compound O.[Na+].[Cl-] HPALAKNZSZLMCH-UHFFFAOYSA-M 0.000 description 1
- 239000000600 sorbitol Substances 0.000 description 1
- 210000000952 spleen Anatomy 0.000 description 1
- 239000008107 starch Substances 0.000 description 1
- 229940032147 starch Drugs 0.000 description 1
- 239000007858 starting material Substances 0.000 description 1
- 239000008117 stearic acid Substances 0.000 description 1
- 230000000638 stimulation Effects 0.000 description 1
- 239000004575 stone Substances 0.000 description 1
- 238000000859 sublimation Methods 0.000 description 1
- 230000008022 sublimation Effects 0.000 description 1
- 239000001384 succinic acid Substances 0.000 description 1
- 229940014800 succinic anhydride Drugs 0.000 description 1
- 238000009495 sugar coating Methods 0.000 description 1
- 239000000829 suppository Substances 0.000 description 1
- 239000004094 surface-active agent Substances 0.000 description 1
- 239000003765 sweetening agent Substances 0.000 description 1
- 230000024587 synaptic transmission, glutamatergic Effects 0.000 description 1
- 239000000454 talc Substances 0.000 description 1
- 229910052623 talc Inorganic materials 0.000 description 1
- 235000012222 talc Nutrition 0.000 description 1
- 108091008646 testicular receptors Proteins 0.000 description 1
- CZDYPVPMEAXLPK-UHFFFAOYSA-N tetramethylsilane Chemical group C[Si](C)(C)C CZDYPVPMEAXLPK-UHFFFAOYSA-N 0.000 description 1
- 238000011200 topical administration Methods 0.000 description 1
- 230000008733 trauma Effects 0.000 description 1
- YNJBWRMUSHSURL-UHFFFAOYSA-N trichloroacetic acid Chemical compound OC(=O)C(Cl)(Cl)Cl YNJBWRMUSHSURL-UHFFFAOYSA-N 0.000 description 1
- 241001430294 unidentified retrovirus Species 0.000 description 1
- 238000011144 upstream manufacturing Methods 0.000 description 1
- 230000009385 viral infection Effects 0.000 description 1
- 230000003612 virological effect Effects 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
- 150000003722 vitamin derivatives Chemical class 0.000 description 1
- 239000000080 wetting agent Substances 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/28—Halogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP02026597A EP1424333A1 (en) | 2002-11-28 | 2002-11-28 | Halothenoyl-cyclopropane-1-carboxylic acid derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT1565451E true PT1565451E (pt) | 2007-08-03 |
Family
ID=32241303
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT03811772T PT1565451E (pt) | 2002-11-28 | 2003-11-25 | Derivados do ácido halotenoil-ciclopropano-1-carboxílico. |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US20060116329A1 (enExample) |
| EP (2) | EP1424333A1 (enExample) |
| JP (1) | JP4522864B2 (enExample) |
| AT (1) | ATE361921T1 (enExample) |
| AU (1) | AU2003296596B2 (enExample) |
| CA (1) | CA2507597A1 (enExample) |
| CY (1) | CY1106692T1 (enExample) |
| DE (1) | DE60313798T2 (enExample) |
| DK (1) | DK1565451T3 (enExample) |
| ES (1) | ES2286509T3 (enExample) |
| PT (1) | PT1565451E (enExample) |
| SI (1) | SI1565451T1 (enExample) |
| WO (1) | WO2004048361A1 (enExample) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1475088A1 (en) * | 2003-05-05 | 2004-11-10 | Newron Pharmaceuticals S.p.A. | Use of kynurenine-3-hydroxylase inhibitors for the preparation of medicaments for the treatment of l-dopa induced movement disorders, dyskinesias, drug addiction, pain and cataract |
| GB2402940A (en) * | 2004-08-19 | 2004-12-22 | Pfizer Ltd | Biomarkers of inflammation and/or macrophage activation |
| JP2008535892A (ja) * | 2005-04-11 | 2008-09-04 | プロビオドルグ エージー | プロリルエンドペプチダーゼの阻害剤 |
| AR086992A1 (es) | 2011-06-20 | 2014-02-05 | Bayer Ip Gmbh | Tienilpiri(mi)dinilpirazoles |
| JP6275690B2 (ja) * | 2012-04-05 | 2018-02-07 | シーエイチディーアイ ファウンデーション，インコーポレーテッド | キヌレニン−３−モノオキシゲナーゼインヒビターおよびその医薬組成物ならびにこれらの使用方法 |
| JP6449893B2 (ja) * | 2013-09-26 | 2019-01-09 | シーエイチディーアイ ファウンデーション，インコーポレーテッド | キヌレニン−３−モノオキシゲナーゼ阻害薬、医薬組成物、及びこれらの使用方法 |
| JP2016536350A (ja) | 2013-09-26 | 2016-11-24 | シーエイチディーアイ ファウンデーション，インコーポレーテッド | キヌレニン−３−モノオキシゲナーゼ阻害薬、医薬組成物、及びこれらの使用方法 |
| GB201322512D0 (en) | 2013-12-19 | 2014-02-05 | Glaxosmithkline Ip Dev Ltd | Novel compounds |
| GB201508857D0 (en) | 2015-05-22 | 2015-07-01 | Glaxosmithkline Ip Dev Ltd | Compounds |
| GB201508864D0 (en) | 2015-05-22 | 2015-07-01 | Glaxosmithkline Ip Dev Ltd | Compounds |
| PL450605A1 (pl) | 2024-12-16 | 2026-06-22 | Uniwersytet Łódzki | Zastosowanie inhibitorów enzymów szlaku kynureninowego jako regulatora wzrostu Trichophyton rubrum do zapobiegania lub leczenia grzybic, zwłaszcza wywołanych Trichophyton rubrum |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1278435B (de) * | 1965-01-19 | 1968-09-26 | Merck Ag E | Verfahren zur Herstellung von 1, 2-disubstituierten Cyclopropanderivaten |
| US4022903A (en) * | 1975-06-05 | 1977-05-10 | Abbott Laboratories | α-Thienyl and α-substituted thienyl, phenyl and substituted phenyl cyclopropylomethanols useful as biodegradable insecticides and mollusicides |
| US6274590B1 (en) * | 1993-01-15 | 2001-08-14 | G. D. Searle & Co. | Method of treating skin related conditions |
| JP4176150B2 (ja) * | 1996-10-30 | 2008-11-05 | 塩野義製薬株式会社 | グルタミン酸放出阻害剤および新規化合物 |
| GB9705031D0 (en) * | 1997-03-11 | 1997-04-30 | Pharmacia & Upjohn Spa | 2-substituted benzoyl-cycloalkyl-1-carboxylic acid derivatives |
-
2002
- 2002-11-28 EP EP02026597A patent/EP1424333A1/en not_active Withdrawn
-
2003
- 2003-11-25 CA CA002507597A patent/CA2507597A1/en not_active Abandoned
- 2003-11-25 JP JP2004554463A patent/JP4522864B2/ja not_active Expired - Fee Related
- 2003-11-25 DE DE60313798T patent/DE60313798T2/de not_active Expired - Lifetime
- 2003-11-25 WO PCT/EP2003/013244 patent/WO2004048361A1/en not_active Ceased
- 2003-11-25 AT AT03811772T patent/ATE361921T1/de not_active IP Right Cessation
- 2003-11-25 AU AU2003296596A patent/AU2003296596B2/en not_active Ceased
- 2003-11-25 SI SI200330828T patent/SI1565451T1/sl unknown
- 2003-11-25 US US10/536,307 patent/US20060116329A1/en not_active Abandoned
- 2003-11-25 PT PT03811772T patent/PT1565451E/pt unknown
- 2003-11-25 ES ES03811772T patent/ES2286509T3/es not_active Expired - Lifetime
- 2003-11-25 DK DK03811772T patent/DK1565451T3/da active
- 2003-11-25 EP EP03811772A patent/EP1565451B1/en not_active Expired - Lifetime
-
2007
- 2007-07-02 CY CY20071100873T patent/CY1106692T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JP4522864B2 (ja) | 2010-08-11 |
| WO2004048361A1 (en) | 2004-06-10 |
| CY1106692T1 (el) | 2012-05-23 |
| AU2003296596B2 (en) | 2010-03-04 |
| DK1565451T3 (da) | 2007-09-10 |
| JP2006509753A (ja) | 2006-03-23 |
| DE60313798D1 (en) | 2007-06-21 |
| US20060116329A1 (en) | 2006-06-01 |
| CA2507597A1 (en) | 2004-06-10 |
| ES2286509T3 (es) | 2007-12-01 |
| EP1565451B1 (en) | 2007-05-09 |
| SI1565451T1 (sl) | 2007-08-31 |
| DE60313798T2 (de) | 2008-01-24 |
| ATE361921T1 (de) | 2007-06-15 |
| AU2003296596A1 (en) | 2004-06-18 |
| EP1565451A1 (en) | 2005-08-24 |
| EP1424333A1 (en) | 2004-06-02 |
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