ATE361921T1 - Halothienoylcyclopropan-1-carbonsaeure-derivate - Google Patents

Halothienoylcyclopropan-1-carbonsaeure-derivate

Info

Publication number
ATE361921T1
ATE361921T1 AT03811772T AT03811772T ATE361921T1 AT E361921 T1 ATE361921 T1 AT E361921T1 AT 03811772 T AT03811772 T AT 03811772T AT 03811772 T AT03811772 T AT 03811772T AT E361921 T1 ATE361921 T1 AT E361921T1
Authority
AT
Austria
Prior art keywords
branched
linear
alkyl
halothienoylcyclopropane
acid derivatives
Prior art date
Application number
AT03811772T
Other languages
English (en)
Inventor
Luca Benatti
Ruggero Fariello
Patricia Salvati
Roberto Pellicciari
Carla Caccia
Original Assignee
Newron Pharm Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Newron Pharm Spa filed Critical Newron Pharm Spa
Application granted granted Critical
Publication of ATE361921T1 publication Critical patent/ATE361921T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/28Halogen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
AT03811772T 2002-11-28 2003-11-25 Halothienoylcyclopropan-1-carbonsaeure-derivate ATE361921T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP02026597A EP1424333A1 (de) 2002-11-28 2002-11-28 Halothenoyl-cyclopropan-1-carbonsäure-derivate

Publications (1)

Publication Number Publication Date
ATE361921T1 true ATE361921T1 (de) 2007-06-15

Family

ID=32241303

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03811772T ATE361921T1 (de) 2002-11-28 2003-11-25 Halothienoylcyclopropan-1-carbonsaeure-derivate

Country Status (13)

Country Link
US (1) US20060116329A1 (de)
EP (2) EP1424333A1 (de)
JP (1) JP4522864B2 (de)
AT (1) ATE361921T1 (de)
AU (1) AU2003296596B2 (de)
CA (1) CA2507597A1 (de)
CY (1) CY1106692T1 (de)
DE (1) DE60313798T2 (de)
DK (1) DK1565451T3 (de)
ES (1) ES2286509T3 (de)
PT (1) PT1565451E (de)
SI (1) SI1565451T1 (de)
WO (1) WO2004048361A1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1475088A1 (de) * 2003-05-05 2004-11-10 Newron Pharmaceuticals S.p.A. Kynurenine-3-hydroxylase Hemmer zur Behandlung von L-DOPA bedingten Bewegungsstörungen, Dyskinesien, Sucht, Schmerzen und Katarakt
GB2402940A (en) * 2004-08-19 2004-12-22 Pfizer Ltd Biomarkers of inflammation and/or macrophage activation
JP2008535892A (ja) * 2005-04-11 2008-09-04 プロビオドルグ エージー プロリルエンドペプチダーゼの阻害剤
AR086992A1 (es) 2011-06-20 2014-02-05 Bayer Ip Gmbh Tienilpiri(mi)dinilpirazoles
WO2013151707A1 (en) 2012-04-05 2013-10-10 Chdi Foundation, Inc. Kynurenine-3-monooxygenase inhibitors, pharmaceutical compositions, and methods of use thereof
WO2015047982A2 (en) * 2013-09-26 2015-04-02 Chdi Foundation, Inc. Kynurenine-3-monooxygenase inhibitors, pharmaceutical compositions, and methods of use thereof
JP6449893B2 (ja) * 2013-09-26 2019-01-09 シーエイチディーアイ ファウンデーション,インコーポレーテッド キヌレニン−3−モノオキシゲナーゼ阻害薬、医薬組成物、及びこれらの使用方法
GB201322512D0 (en) 2013-12-19 2014-02-05 Glaxosmithkline Ip Dev Ltd Novel compounds
GB201508857D0 (en) 2015-05-22 2015-07-01 Glaxosmithkline Ip Dev Ltd Compounds
GB201508864D0 (en) 2015-05-22 2015-07-01 Glaxosmithkline Ip Dev Ltd Compounds

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1278435B (de) * 1965-01-19 1968-09-26 Merck Ag E Verfahren zur Herstellung von 1, 2-disubstituierten Cyclopropanderivaten
US4022903A (en) * 1975-06-05 1977-05-10 Abbott Laboratories α-Thienyl and α-substituted thienyl, phenyl and substituted phenyl cyclopropylomethanols useful as biodegradable insecticides and mollusicides
US6274590B1 (en) * 1993-01-15 2001-08-14 G. D. Searle & Co. Method of treating skin related conditions
JP4176150B2 (ja) * 1996-10-30 2008-11-05 塩野義製薬株式会社 グルタミン酸放出阻害剤および新規化合物
GB9705031D0 (en) * 1997-03-11 1997-04-30 Pharmacia & Upjohn Spa 2-substituted benzoyl-cycloalkyl-1-carboxylic acid derivatives

Also Published As

Publication number Publication date
CY1106692T1 (el) 2012-05-23
ES2286509T3 (es) 2007-12-01
CA2507597A1 (en) 2004-06-10
AU2003296596A1 (en) 2004-06-18
DE60313798D1 (en) 2007-06-21
EP1565451A1 (de) 2005-08-24
JP4522864B2 (ja) 2010-08-11
EP1565451B1 (de) 2007-05-09
AU2003296596B2 (en) 2010-03-04
US20060116329A1 (en) 2006-06-01
WO2004048361A1 (en) 2004-06-10
SI1565451T1 (sl) 2007-08-31
DE60313798T2 (de) 2008-01-24
DK1565451T3 (da) 2007-09-10
JP2006509753A (ja) 2006-03-23
EP1424333A1 (de) 2004-06-02
PT1565451E (pt) 2007-08-03

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