DK1565451T3 - Halogenthienoylcyclopropan-1-carboxylsyre-derivater - Google Patents

Halogenthienoylcyclopropan-1-carboxylsyre-derivater

Info

Publication number
DK1565451T3
DK1565451T3 DK03811772T DK03811772T DK1565451T3 DK 1565451 T3 DK1565451 T3 DK 1565451T3 DK 03811772 T DK03811772 T DK 03811772T DK 03811772 T DK03811772 T DK 03811772T DK 1565451 T3 DK1565451 T3 DK 1565451T3
Authority
DK
Denmark
Prior art keywords
branched
linear
alkyl
halogenthienoylcyclopropan
carboxylic acid
Prior art date
Application number
DK03811772T
Other languages
English (en)
Inventor
Luca Benatti
Ruggero Fariello
Patricia Salvati
Roberto Pellicciari
Carla Caccia
Original Assignee
Newron Pharm Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Newron Pharm Spa filed Critical Newron Pharm Spa
Application granted granted Critical
Publication of DK1565451T3 publication Critical patent/DK1565451T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/28Halogen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
DK03811772T 2002-11-28 2003-11-25 Halogenthienoylcyclopropan-1-carboxylsyre-derivater DK1565451T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP02026597A EP1424333A1 (en) 2002-11-28 2002-11-28 Halothenoyl-cyclopropane-1-carboxylic acid derivatives
PCT/EP2003/013244 WO2004048361A1 (en) 2002-11-28 2003-11-25 Halothenoyl-cyclopropane-1-carboxylic acid derivatives

Publications (1)

Publication Number Publication Date
DK1565451T3 true DK1565451T3 (da) 2007-09-10

Family

ID=32241303

Family Applications (1)

Application Number Title Priority Date Filing Date
DK03811772T DK1565451T3 (da) 2002-11-28 2003-11-25 Halogenthienoylcyclopropan-1-carboxylsyre-derivater

Country Status (13)

Country Link
US (1) US20060116329A1 (da)
EP (2) EP1424333A1 (da)
JP (1) JP4522864B2 (da)
AT (1) ATE361921T1 (da)
AU (1) AU2003296596B2 (da)
CA (1) CA2507597A1 (da)
CY (1) CY1106692T1 (da)
DE (1) DE60313798T2 (da)
DK (1) DK1565451T3 (da)
ES (1) ES2286509T3 (da)
PT (1) PT1565451E (da)
SI (1) SI1565451T1 (da)
WO (1) WO2004048361A1 (da)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1475088A1 (en) * 2003-05-05 2004-11-10 Newron Pharmaceuticals S.p.A. Use of kynurenine-3-hydroxylase inhibitors for the preparation of medicaments for the treatment of l-dopa induced movement disorders, dyskinesias, drug addiction, pain and cataract
GB2402940A (en) * 2004-08-19 2004-12-22 Pfizer Ltd Biomarkers of inflammation and/or macrophage activation
EP1869008A1 (en) * 2005-04-11 2007-12-26 Probiodrug AG Inhibitors of prolyl endopeptidase
WO2012175513A1 (en) 2011-06-20 2012-12-27 Bayer Intellectual Property Gmbh Thienylpyri(mi)dinylpyrazole
CN104244939A (zh) * 2012-04-05 2014-12-24 Chdi基金会股份有限公司 犬尿氨酸-3-单加氧酶抑制剂、其药物组合物及其使用方法
JP2016536350A (ja) 2013-09-26 2016-11-24 シーエイチディーアイ ファウンデーション,インコーポレーテッド キヌレニン−3−モノオキシゲナーゼ阻害薬、医薬組成物、及びこれらの使用方法
US9938252B2 (en) 2013-09-26 2018-04-10 Chdi Foundation, Inc. Kynurenine-3-monooxygenase inhibitors, pharmaceutical compositions, and methods of use thereof
GB201322512D0 (en) 2013-12-19 2014-02-05 Glaxosmithkline Ip Dev Ltd Novel compounds
GB201508857D0 (en) 2015-05-22 2015-07-01 Glaxosmithkline Ip Dev Ltd Compounds
GB201508864D0 (en) 2015-05-22 2015-07-01 Glaxosmithkline Ip Dev Ltd Compounds

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1278435B (de) * 1965-01-19 1968-09-26 Merck Ag E Verfahren zur Herstellung von 1, 2-disubstituierten Cyclopropanderivaten
US4022903A (en) * 1975-06-05 1977-05-10 Abbott Laboratories α-Thienyl and α-substituted thienyl, phenyl and substituted phenyl cyclopropylomethanols useful as biodegradable insecticides and mollusicides
US6274590B1 (en) * 1993-01-15 2001-08-14 G. D. Searle & Co. Method of treating skin related conditions
WO1998018760A1 (fr) * 1996-10-30 1998-05-07 Shionogi & Co., Ltd. Inhibiteur de la liberation du glutamate et nouveaux composes
GB9705031D0 (en) * 1997-03-11 1997-04-30 Pharmacia & Upjohn Spa 2-substituted benzoyl-cycloalkyl-1-carboxylic acid derivatives

Also Published As

Publication number Publication date
CA2507597A1 (en) 2004-06-10
JP4522864B2 (ja) 2010-08-11
AU2003296596B2 (en) 2010-03-04
US20060116329A1 (en) 2006-06-01
ATE361921T1 (de) 2007-06-15
EP1565451B1 (en) 2007-05-09
CY1106692T1 (el) 2012-05-23
PT1565451E (pt) 2007-08-03
DE60313798D1 (en) 2007-06-21
JP2006509753A (ja) 2006-03-23
DE60313798T2 (de) 2008-01-24
SI1565451T1 (sl) 2007-08-31
WO2004048361A1 (en) 2004-06-10
AU2003296596A1 (en) 2004-06-18
EP1424333A1 (en) 2004-06-02
ES2286509T3 (es) 2007-12-01
EP1565451A1 (en) 2005-08-24

Similar Documents

Publication Publication Date Title
CY1106692T1 (el) Παραγωγα του αλοξενοϋλ-κυκλοπροπαν-1-καρβοξυλικου οξεος
HN1997000027A (es) Derivados de 6-fenil piridil - 2 amina
DK1442024T3 (da) Aminobenzamidderivater som glycogensystasekinase 3 beta-inhibitorer
DK0931788T3 (da) Metalloproteasehæmmere
DE60225671D1 (de) Pharmazeutisch wirksame piperidinderivate
DK1076663T3 (da) Funktionaliserede alkyl- og alkenylsidekædederivater af glycinamider som farnesyltransferaseinhibitorer
DK1424330T3 (da) Aktivator for peroxisom proliferator-responsiv receptor delta
EP1490371A4 (en) TRICYCLIC COMPOUNDS BASED ON THIOPENE AND PHARMACEUTICAL COMPOSITIONS COMPRISING SAID COMPOUNDS
DK1485377T3 (da) Pyranoner egnede som ATM-inhibitorer
ES2177275T3 (es) Derivados de oxadiazolina y su uso como insecticidas.
FI20001593A0 (fi) Comt-entsyymiä inhiboivaa aktiivisuutta omaavia kumariinijohdannaisia
DE60223904D1 (de) Benzylaminanalogen
DK0753511T3 (da) 4-indol-1-ylsmørsyrederivater, deres fremstilling og deres anvendelse som inhibitorer af alfa 1-adrenerge receptorer og testosteron-5alfa-reduktaser
DK1663122T3 (da) Mundskyllesammensætninger indeholdende N-acyl-argininalkylestersalte
ATE201402T1 (de) Optisch aktive thiazolidinonderivate
HUP0303760A2 (hu) AZ NF-kB faktort gátló szubsztituált benzoesavszármazékok és ezeket tartalmazó gyógyszerkészítmények
ES2190781T3 (es) Derivados de 1-trifluorometil-4-hidroxi-7-piperidinil-aminometilcromano.
ECSP045176A (es) Derivados de 5-(piridin-3-il)-1-azabiciclo[3.2.1]octano, su preparacion y su aplicación en terapeutica
ATE199717T1 (de) Benzothiophenverbindungen, ihre anwendungen und zusammensetzungen
DK0912573T3 (da) Camptothecinderivater, som er isoleret fra Mappia foetida, og anvendelse deraf som syntoner for nye lægemidler og som terapeutiske midler
DE60113808D1 (de) Therapeutikum oder Prophylaktikum für Lebererkrankungen, enthaltend ein Diaminotrifluorethylpyridin-Derivat
PE20030758A1 (es) 1,3-diarilprop-2-en-1-onas, composiciones que las contienen y su utilizacion
ATE284379T1 (de) Aminderivate
ATE259346T1 (de) Benflumentolderivative und ihre verwendung gegen parasitäre protozoen und trematoden
AR055565A1 (es) Compuestos de aminoacidos fosfinicos a un procedimiento para su preparacion y a las composiciones farmaceuticas que los contienen