PT1546734E - Anticorpos monoclonais de amiloide beta n 11 truncados, composições, métodos e utilizações - Google Patents

Anticorpos monoclonais de amiloide beta n 11 truncados, composições, métodos e utilizações Download PDF

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Publication number
PT1546734E
PT1546734E PT37981560T PT03798156T PT1546734E PT 1546734 E PT1546734 E PT 1546734E PT 37981560 T PT37981560 T PT 37981560T PT 03798156 T PT03798156 T PT 03798156T PT 1546734 E PT1546734 E PT 1546734E
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PT
Portugal
Prior art keywords
compositions
methods
monoclonal antibodies
truncated amyloid
beta monoclonal
Prior art date
Application number
PT37981560T
Other languages
English (en)
Inventor
Hubert Mercken Marc
Maria Pierre Pelagie Vandermeeren Marc
Original Assignee
Janssen Pharmaceutica Nv
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Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of PT1546734E publication Critical patent/PT1546734E/pt

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
    • G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
    • G01N2333/4701—Details
    • G01N2333/4709—Amyloid plaque core protein
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/28—Neurological disorders
    • G01N2800/2814—Dementia; Cognitive disorders
    • G01N2800/2821—Alzheimer
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Psychiatry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Cardiology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
PT37981560T 2002-09-27 2003-09-09 Anticorpos monoclonais de amiloide beta n 11 truncados, composições, métodos e utilizações PT1546734E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/EP2002/011062 WO2004029629A1 (en) 2002-09-27 2002-09-27 N-11 truncated amyloid-beta nomoclonal antibodies, compositions, methods and uses

Publications (1)

Publication Number Publication Date
PT1546734E true PT1546734E (pt) 2016-03-01

Family

ID=32039081

Family Applications (1)

Application Number Title Priority Date Filing Date
PT37981560T PT1546734E (pt) 2002-09-27 2003-09-09 Anticorpos monoclonais de amiloide beta n 11 truncados, composições, métodos e utilizações

Country Status (14)

Country Link
US (2) US9329189B2 (pt)
EP (1) EP1546734B1 (pt)
JP (3) JP2006513988A (pt)
CN (2) CN101367875B (pt)
AU (1) AU2003266378B2 (pt)
CA (1) CA2498058C (pt)
CY (1) CY1117387T1 (pt)
DK (1) DK1546734T3 (pt)
ES (1) ES2560853T3 (pt)
HK (1) HK1081647A1 (pt)
HU (1) HUE028331T2 (pt)
PT (1) PT1546734E (pt)
SI (1) SI1546734T1 (pt)
WO (2) WO2004029629A1 (pt)

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US20050129695A1 (en) * 2003-03-28 2005-06-16 Marc Mercken Anti-amyloid antibodies, compositions, methods and uses
US7732162B2 (en) 2003-05-05 2010-06-08 Probiodrug Ag Inhibitors of glutaminyl cyclase for treating neurodegenerative diseases
US7807165B2 (en) 2004-07-30 2010-10-05 Rinat Neuroscience Corp. Antibodies directed against amyloid-beta peptide and methods using same
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UY29504A1 (es) 2005-04-29 2006-10-31 Rinat Neuroscience Corp Anticuerpos dirigidos contra el péptido amiloide beta y métodos que utilizan los mismos.
CA2631195C (en) 2005-11-30 2016-04-05 Abbott Laboratories Monoclonal antibodies against amyloid beta protein and uses thereof
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EP2124952A2 (en) 2007-02-27 2009-12-02 Abbott GmbH & Co. KG Method for the treatment of amyloidoses
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US7931899B2 (en) 2007-05-14 2011-04-26 Medtronic, Inc Humanized anti-amyloid beta antibodies
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Also Published As

Publication number Publication date
CA2498058A1 (en) 2004-04-08
US9329189B2 (en) 2016-05-03
US20170192016A1 (en) 2017-07-06
EP1546734B1 (en) 2015-11-11
EP1546734A1 (en) 2005-06-29
WO2004029630A1 (en) 2004-04-08
CA2498058C (en) 2013-02-12
US20060127954A1 (en) 2006-06-15
HUE028331T2 (en) 2016-12-28
CN101367875B (zh) 2013-06-12
WO2004029629A1 (en) 2004-04-08
JP2017149719A (ja) 2017-08-31
ES2560853T3 (es) 2016-02-23
HK1081647A1 (en) 2006-05-19
AU2003266378B2 (en) 2010-01-21
AU2003266378A1 (en) 2004-04-19
US9939452B2 (en) 2018-04-10
JP2006513988A (ja) 2006-04-27
CY1117387T1 (el) 2017-04-26
CN1685236A (zh) 2005-10-19
JP2014208678A (ja) 2014-11-06
DK1546734T3 (en) 2016-02-08
CN100418984C (zh) 2008-09-17
CN101367875A (zh) 2009-02-18
JP6420072B2 (ja) 2018-11-07
SI1546734T1 (sl) 2016-02-29

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