PT1537096E - Derivados de dioxano-2-alquilcarbamatos, sua preparação e sua aplicação em terapia - Google Patents

Derivados de dioxano-2-alquilcarbamatos, sua preparação e sua aplicação em terapia Download PDF

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Publication number
PT1537096E
PT1537096E PT03758282T PT03758282T PT1537096E PT 1537096 E PT1537096 E PT 1537096E PT 03758282 T PT03758282 T PT 03758282T PT 03758282 T PT03758282 T PT 03758282T PT 1537096 E PT1537096 E PT 1537096E
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Prior art keywords
therapeutics
dioxane
derivatives
preparation
application
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Application number
PT03758282T
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English (en)
Inventor
Gihad Dargazanli
Florence Medaisko
Ahmed Abouabdellah
Christian Hoornaert
Adrien Tak Li
Michele Bas
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Sanofi Aventis
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Publication of PT1537096E publication Critical patent/PT1537096E/pt

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D319/00Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/041,3-Dioxanes; Hydrogenated 1,3-dioxanes
    • C07D319/061,3-Dioxanes; Hydrogenated 1,3-dioxanes not condensed with other rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • AHUMAN NECESSITIES
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    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
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    • A61P1/08Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/02Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/04Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C235/06Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pulmonology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Urology & Nephrology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Psychiatry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Otolaryngology (AREA)
  • Hospice & Palliative Care (AREA)
  • Molecular Biology (AREA)
  • Dermatology (AREA)
  • Psychology (AREA)
  • AIDS & HIV (AREA)
  • Nutrition Science (AREA)
PT03758282T 2002-08-29 2003-08-27 Derivados de dioxano-2-alquilcarbamatos, sua preparação e sua aplicação em terapia PT1537096E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0210707A FR2843964B1 (fr) 2002-08-29 2002-08-29 Derives de dioxane-2-alkylcarbamates, leur preparation et leur application en therapeutique

Publications (1)

Publication Number Publication Date
PT1537096E true PT1537096E (pt) 2008-12-11

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ID=31502974

Family Applications (2)

Application Number Title Priority Date Filing Date
PT07013954T PT1840125E (pt) 2002-08-29 2003-08-27 Intermediários para a produção de dioxano-2-alquilcarbamatos
PT03758282T PT1537096E (pt) 2002-08-29 2003-08-27 Derivados de dioxano-2-alquilcarbamatos, sua preparação e sua aplicação em terapia

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Application Number Title Priority Date Filing Date
PT07013954T PT1840125E (pt) 2002-08-29 2003-08-27 Intermediários para a produção de dioxano-2-alquilcarbamatos

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US (4) US7119116B2 (pt)
EP (2) EP1537096B1 (pt)
JP (2) JP4585854B2 (pt)
KR (2) KR101051192B1 (pt)
CN (3) CN101906071A (pt)
AR (1) AR041053A1 (pt)
AT (2) ATE434598T1 (pt)
AU (1) AU2003274292B2 (pt)
BR (1) BR0313846A (pt)
CA (2) CA2700319C (pt)
CO (1) CO5700820A2 (pt)
CY (2) CY1108792T1 (pt)
DE (2) DE60328138D1 (pt)
DK (2) DK1537096T3 (pt)
EA (1) EA008218B1 (pt)
ES (2) ES2329181T3 (pt)
FR (1) FR2843964B1 (pt)
HK (2) HK1108157A1 (pt)
HR (2) HRP20050190B1 (pt)
IL (1) IL166882A (pt)
IS (1) IS2733B (pt)
MA (1) MA27390A1 (pt)
ME (2) MEP24208A (pt)
MX (1) MXPA05002319A (pt)
NO (2) NO331165B1 (pt)
NZ (1) NZ538404A (pt)
PL (1) PL209339B1 (pt)
PT (2) PT1840125E (pt)
RS (2) RS20100169A (pt)
SI (2) SI1840125T1 (pt)
TN (1) TNSN05057A1 (pt)
TW (2) TWI294878B (pt)
UA (1) UA82847C2 (pt)
WO (1) WO2004020430A2 (pt)
ZA (1) ZA200501537B (pt)

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FR2843964B1 (fr) * 2002-08-29 2004-10-01 Sanofi Synthelabo Derives de dioxane-2-alkylcarbamates, leur preparation et leur application en therapeutique
CA2501506C (en) * 2002-10-07 2014-02-11 Daniele Piomelli Modulation of anxiety through blockade of anandamide hydrolysis
FR2854633B1 (fr) * 2003-05-07 2005-06-24 Sanofi Synthelabo Derives de piperidinyl-et piperazinyl-alkylcarbamates, leur preparation et leur application en therapeutique
FR2865205B1 (fr) * 2004-01-16 2006-02-24 Sanofi Synthelabo Derives de type aryloxyalkylcarbamates, leur preparation et leur application en therapeutique
FR2866886B1 (fr) 2004-02-26 2007-08-31 Sanofi Synthelabo Derives d'aryl-et d'heteroaryl-akylcarbamates, leur preparation et leur application en therapeutique
FR2866884B1 (fr) * 2004-02-26 2007-08-31 Sanofi Synthelabo Derives d'aryl-et d'heteroaryl-piperidinecarboxylates, leur preparation et leur application en therapeutique
FR2866885B1 (fr) * 2004-02-26 2007-08-31 Sanofi Synthelabo Derives de piperidinylalkylcarbamates, leur prepation et leur application en therapeutique
FR2866888B1 (fr) * 2004-02-26 2006-05-05 Sanofi Synthelabo Derives de alkylpiperazine- et alkylhomopiperazine- carboxylates, leur preparation et leur application en therapeutique
US7269708B2 (en) * 2004-04-20 2007-09-11 Rambus Inc. Memory controller for non-homogenous memory system
US20080103209A1 (en) * 2004-04-23 2008-05-01 The Regents Of The University Of California Compounds And Methods For Treating Non-Inflammatory Pain Using Ppar Alpha Agonists
DE102004039326A1 (de) * 2004-08-12 2006-02-16 Abbott Gmbh & Co. Kg Neue medizinische Verwendungen und Verfahren
MX2007010076A (es) 2005-02-17 2007-10-16 Astellas Pharma Inc Derivado de heterociclico-1-carboxilato que contiene nitrogeno no aromatico de piridilo.
FR2885364B1 (fr) * 2005-05-03 2007-06-29 Sanofi Aventis Sa Derives d'alkyl-, alkenyl-et alkynylcarbamates, leur preparation et leur application en therapeutique
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US20080089845A1 (en) * 2006-09-07 2008-04-17 N.V. Organon Methods for determining effective doses of fatty acid amide hydrolase inhibitors in vivo
US20090099240A1 (en) * 2006-10-02 2009-04-16 N.V. Organon Methods for treating energy metabolism disorders by inhibiting fatty acid amide hydrolase activity
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