PT1405858E - Processo de produção de derivado asparagina com cadeia de açúcar - Google Patents

Processo de produção de derivado asparagina com cadeia de açúcar

Info

Publication number
PT1405858E
PT1405858E PT2743643T PT02743643T PT1405858E PT 1405858 E PT1405858 E PT 1405858E PT 2743643 T PT2743643 T PT 2743643T PT 02743643 T PT02743643 T PT 02743643T PT 1405858 E PT1405858 E PT 1405858E
Authority
PT
Portugal
Prior art keywords
sugar chain
chain asparagine
producing sugar
asparagine derivative
derivative
Prior art date
Application number
PT2743643T
Other languages
English (en)
Inventor
Yasuhiro Kajihara
Ken Sasaki
Original Assignee
Yasuhiro Kajihara
Glytech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yasuhiro Kajihara, Glytech Inc filed Critical Yasuhiro Kajihara
Publication of PT1405858E publication Critical patent/PT1405858E/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/10Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals directly attached to heterocyclic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02Acyclic radicals, not substituted by cyclic structures
    • C07H15/12Acyclic radicals, not substituted by cyclic structures attached to a nitrogen atom of the saccharide radical
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H5/00Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium
    • C07H5/04Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium to nitrogen
    • C07H5/06Aminosugars
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H7/00Compounds containing non-saccharide radicals linked to saccharide radicals by a carbon-to-carbon bond
    • C07H7/02Acyclic radicals
    • C07H7/027Keto-aldonic acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00Preparation of nitrogen-containing organic compounds
    • C12P13/04Alpha- or beta- amino acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/04Polysaccharides, i.e. compounds containing more than five saccharide radicals attached to each other by glycosidic bonds
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/26Preparation of nitrogen-containing carbohydrates
    • C12P19/28N-glycosides
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Saccharide Compounds (AREA)
  • Peptides Or Proteins (AREA)
PT2743643T 2001-06-19 2002-06-19 Processo de produção de derivado asparagina com cadeia de açúcar PT1405858E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2001185685 2001-06-19

Publications (1)

Publication Number Publication Date
PT1405858E true PT1405858E (pt) 2013-03-11

Family

ID=19025226

Family Applications (1)

Application Number Title Priority Date Filing Date
PT2743643T PT1405858E (pt) 2001-06-19 2002-06-19 Processo de produção de derivado asparagina com cadeia de açúcar

Country Status (12)

Country Link
US (1) US7135566B2 (pt)
EP (3) EP2481746A1 (pt)
JP (1) JP4323139B2 (pt)
KR (2) KR100885149B1 (pt)
CN (1) CN100343264C (pt)
AU (1) AU2002346294B2 (pt)
CA (1) CA2451971C (pt)
CY (1) CY1114536T1 (pt)
DK (1) DK1405858T3 (pt)
ES (1) ES2402089T3 (pt)
PT (1) PT1405858E (pt)
WO (1) WO2003008431A1 (pt)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7943763B2 (en) 2002-07-05 2011-05-17 Otsuka Chemical Holdings Co., Ltd. Process for preparing glycopeptides having asparagine-linked oligosaccharides, and the glycopeptides
TWI335920B (en) * 2002-12-24 2011-01-11 Yasuhiro Kajihara Sugar chain asparagine derivatives, sugar chain asparagine and sugar chain and manufacture thereof
CN100413889C (zh) * 2002-12-24 2008-08-27 大塚化学株式会社 糖链天冬酰胺衍生物、糖链天冬酰胺和糖链以及它们的制造方法
JP4495598B2 (ja) * 2002-12-26 2010-07-07 康宏 梶原 糖鎖アスパラギン誘導体およびその製造方法
AU2004209371B2 (en) * 2003-02-04 2008-05-01 Glytech, Inc. Process for producing sugar chain asparagine derivative
CN100500694C (zh) * 2003-06-30 2009-06-17 大塚化学株式会社 二唾液酸十一糖链天冬酰胺-脂肪酸酰胺、含有该化合物的药物
EP1650226A4 (en) 2003-07-28 2011-06-15 Yasuhiro Kajihara AMINISHED SUGAR CHAIN DERIVATIVES OF THE COMPLEX TYPE AND MANUFACTURING METHOD THEREFOR
FI20031536A0 (fi) * 2003-10-20 2003-10-20 Biotie Therapies Oyj Korkean affiniteetin ligandit influenssavirukselle ja menetelmät niiden valmistamiseen
EP1698634A4 (en) * 2003-12-26 2010-11-03 Shionogi & Co SYNTHESIS OF A STRUCTURE OF INNER SUGAR CHAINS OF GLYCOPROTEIN LINKED WITH ASPARAGIN
JP2006022191A (ja) * 2004-07-07 2006-01-26 Yasuhiro Kajiwara 3分岐型糖鎖アスパラギン誘導体、該糖鎖アスパラギン、該糖鎖およびそれらの製造方法
TWI342880B (en) * 2005-07-19 2011-06-01 Otsuka Chemical Co Ltd Method for producing sugar chain derivatives, and sugar chain derivatives
JP5004464B2 (ja) * 2005-12-02 2012-08-22 大塚化学株式会社 糖鎖修飾リポソーム
CN101437836B (zh) 2006-03-29 2013-07-24 株式会社糖锁工学研究所 肽的硫酯化合物的制造方法
JP2009155353A (ja) * 2006-03-30 2009-07-16 Yokohama City Univ 糖鎖化合物の製造方法
JP2007297429A (ja) * 2006-04-27 2007-11-15 Institute Of Physical & Chemical Research 糖鎖ライブラリの作製方法及びその利用
KR101534881B1 (ko) 2007-07-31 2015-07-07 가부시키가이샤 도우사 고가쿠 겐큐쇼 펩티드의 제조방법
JP5604297B2 (ja) 2008-06-17 2014-10-08 株式会社糖鎖工学研究所 糖鎖付加glp−1ペプチド
AU2009283678B2 (en) 2008-08-19 2014-01-16 Glytech, Inc. Glycoprotein production method and screening method
TW201031749A (en) 2009-02-10 2010-09-01 Otsuka Chemical Co Ltd IgG-Fc fragment and method for manufacturing the same
EP2455396A4 (en) 2009-07-16 2013-05-01 Otsuka Chemical Co Ltd EXTRACELLULAR AILIM DOMAIN PLACED WITH SUGAR CHAINS AND METHOD OF MANUFACTURING THE SAME
WO2011027868A1 (ja) 2009-09-03 2011-03-10 公益財団法人野口研究所 11糖シアリルオリゴ糖ペプチドの製造方法
US20120264684A1 (en) 2009-10-30 2012-10-18 Yasuhiro Kajihara Glycosylated Form of Antigenic GLP-1 Analogue
JP5813294B2 (ja) * 2010-04-30 2015-11-17 旭化成株式会社 糖ペプチド誘導体及びその製造方法
JP5680576B2 (ja) * 2011-03-03 2015-03-04 旭化成株式会社 11糖シアリルオリゴ糖アスパラギンの製造方法
JP5925760B2 (ja) * 2011-03-10 2016-05-25 株式会社糖鎖工学研究所 シアリル糖鎖を有する糖ペプチドの製造方法、当該製造方法に使用するシアリル糖鎖付加アミノ酸誘導体、及び当該糖ペプチド
CN103946234B (zh) 2011-09-04 2017-06-30 株式会社糖锁工学研究所 附加糖链的多肽和含有该多肽的医药组合物
KR102031998B1 (ko) 2011-09-04 2019-10-14 가부시키가이샤 도우사 고가쿠 겐큐쇼 당쇄 부가 폴리펩티드 및 당해 폴리펩티드를 포함하는 의약 조성물
CN102382178B (zh) * 2011-10-21 2013-05-29 山东大学 一种唾液酸糖肽的分离方法
JP6211533B2 (ja) 2012-11-22 2017-10-11 株式会社糖鎖工学研究所 糖鎖付加リンカー、糖鎖付加リンカー部分と生理活性物質部分とを含む化合物またはその塩、及びそれらの製造方法
EP2926829B1 (en) 2012-11-30 2018-07-25 Glytech, Inc. Sugar chain-attached linker, compound containing sugar chain-attached linker and physiologically active substance or salt thereof, and method for producing same
ES2687801T3 (es) 2013-03-29 2018-10-29 Glytech, Inc. Polipéptido presentando cadenas de azúcares sialiladas unidas al mismo
DK2980098T3 (en) 2013-03-30 2019-01-28 Glytech Inc (Sugar chain) -POLYPEPTIDKOMPLEKS
JP6618176B2 (ja) * 2015-11-30 2019-12-11 公益財団法人野口研究所 7糖オリゴ糖の製造方法
TW201930345A (zh) 2017-12-27 2019-08-01 日商協和醱酵麒麟有限公司 Il-2改型體
TW202334175A (zh) * 2021-10-29 2023-09-01 日商第一三共股份有限公司 新穎寡糖、該寡糖之製造中間體及其等之製造方法
WO2023145812A1 (ja) * 2022-01-31 2023-08-03 株式会社日本触媒 グルコセレブロシダーゼ活性を有する糖鎖付加タンパク質
WO2023219065A1 (ja) * 2022-05-13 2023-11-16 株式会社糖鎖工学研究所 シアル酸含有糖鎖の製造方法
WO2024122608A1 (ja) * 2022-12-07 2024-06-13 Khネオケム株式会社 糖ペプチドを分離する方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH07224082A (ja) 1994-02-14 1995-08-22 Rikagaku Kenkyusho アスパラギン結合型糖誘導体及びその製法
JPH0924082A (ja) * 1995-07-12 1997-01-28 Chieko Sugimura 抗菌性小児ハリ
JPH10306099A (ja) * 1997-03-04 1998-11-17 Noguchi Inst 新規複合糖ペプチドおよびその製法
JPH11255807A (ja) 1998-03-13 1999-09-21 Noguchi Inst 糖鎖アスパラギン活性エステル誘導体とその合成中間体

Also Published As

Publication number Publication date
EP1405858B1 (en) 2013-01-02
CY1114536T1 (el) 2016-10-05
KR20060084456A (ko) 2006-07-24
WO2003008431A1 (fr) 2003-01-30
KR100775805B1 (ko) 2007-11-12
AU2002346294B2 (en) 2006-08-17
JP2003128703A (ja) 2003-05-08
KR100885149B1 (ko) 2009-02-23
EP1405858A1 (en) 2004-04-07
US20040181054A1 (en) 2004-09-16
EP1405858A4 (en) 2009-11-25
ES2402089T3 (es) 2013-04-26
JP4323139B2 (ja) 2009-09-02
US7135566B2 (en) 2006-11-14
EP2481746A1 (en) 2012-08-01
CN100343264C (zh) 2007-10-17
KR20040026667A (ko) 2004-03-31
CA2451971C (en) 2010-09-07
EP1405858A8 (en) 2004-11-10
EP2322533A1 (en) 2011-05-18
CA2451971A1 (en) 2003-01-30
CN1543471A (zh) 2004-11-03
DK1405858T3 (da) 2013-02-18

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