PT1381366E - Derivados indole, azaindole e heterocíclicos relacionados de amidopiperazina - Google Patents
Derivados indole, azaindole e heterocíclicos relacionados de amidopiperazina Download PDFInfo
- Publication number
- PT1381366E PT1381366E PT02764315T PT02764315T PT1381366E PT 1381366 E PT1381366 E PT 1381366E PT 02764315 T PT02764315 T PT 02764315T PT 02764315 T PT02764315 T PT 02764315T PT 1381366 E PT1381366 E PT 1381366E
- Authority
- PT
- Portugal
- Prior art keywords
- azaindole
- heteroaryl
- group
- indole
- related heterocyclic
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D209/20—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals substituted additionally by nitrogen atoms, e.g. tryptophane
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/54—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
- C07D231/56—Benzopyrazoles; Hydrogenated benzopyrazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- C07D307/80—Radicals substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- C07D307/81—Radicals substituted by nitrogen atoms not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Oncology (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Immunology (AREA)
- Tropical Medicine & Parasitology (AREA)
- AIDS & HIV (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Indole Compounds (AREA)
- Furan Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US28634701P | 2001-04-25 | 2001-04-25 |
Publications (1)
Publication Number | Publication Date |
---|---|
PT1381366E true PT1381366E (pt) | 2009-07-21 |
Family
ID=23098194
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT02764315T PT1381366E (pt) | 2001-04-25 | 2002-04-23 | Derivados indole, azaindole e heterocíclicos relacionados de amidopiperazina |
Country Status (15)
Country | Link |
---|---|
US (1) | US6825201B2 (pt) |
EP (1) | EP1381366B9 (pt) |
JP (1) | JP4326221B2 (pt) |
CN (1) | CN1330307C (pt) |
AT (1) | ATE429229T1 (pt) |
BR (1) | BR0209153A (pt) |
CA (1) | CA2445190C (pt) |
CY (1) | CY1109219T1 (pt) |
DE (1) | DE60232065D1 (pt) |
DK (1) | DK1381366T3 (pt) |
ES (1) | ES2323859T3 (pt) |
HU (1) | HU230215B1 (pt) |
MX (1) | MXPA03009680A (pt) |
PT (1) | PT1381366E (pt) |
WO (1) | WO2002085301A2 (pt) |
Families Citing this family (52)
Publication number | Priority date | Publication date | Assignee | Title |
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US20040110785A1 (en) * | 2001-02-02 | 2004-06-10 | Tao Wang | Composition and antiviral activity of substituted azaindoleoxoacetic piperazine derivatives |
CN100384423C (zh) * | 2001-02-02 | 2008-04-30 | 布里斯托尔-迈尔斯斯奎布公司 | 取代的氮杂吲哚氧代乙酰哌嗪衍生物的组合物和抗病毒活性 |
US6900206B2 (en) * | 2002-06-20 | 2005-05-31 | Bristol-Myers Squibb Company | Indole, azaindole and related heterocyclic sulfonylureido piperazine derivatives |
US20050075364A1 (en) | 2003-07-01 | 2005-04-07 | Kap-Sun Yeung | Indole, azaindole and related heterocyclic N-substituted piperazine derivatives |
AU2004264724A1 (en) * | 2003-08-14 | 2005-02-24 | Pfizer Inc. | Piperazine derivatives for the treatment of HIV infections |
JP2007512359A (ja) * | 2003-11-19 | 2007-05-17 | メタバシス・セラピューティクス・インコーポレイテッド | 新規なリン含有甲状腺ホルモン様物質 |
US20050124623A1 (en) | 2003-11-26 | 2005-06-09 | Bender John A. | Diazaindole-dicarbonyl-piperazinyl antiviral agents |
US7772271B2 (en) * | 2004-07-14 | 2010-08-10 | Ptc Therapeutics, Inc. | Methods for treating hepatitis C |
US7868037B2 (en) * | 2004-07-14 | 2011-01-11 | Ptc Therapeutics, Inc. | Methods for treating hepatitis C |
US7781478B2 (en) * | 2004-07-14 | 2010-08-24 | Ptc Therapeutics, Inc. | Methods for treating hepatitis C |
JP2008506702A (ja) * | 2004-07-14 | 2008-03-06 | ピーティーシー セラピューティクス,インコーポレーテッド | C型肝炎を治療するための方法 |
WO2006019832A1 (en) * | 2004-07-22 | 2006-02-23 | Ptc Therapeutics, Inc. | Thienopyridines for treating hepatitis c |
KR20200105967A (ko) * | 2004-07-28 | 2020-09-09 | 다케다 야쿠힌 고교 가부시키가이샤 | 피롤로〔2,3-c〕피리딘 화합물, 그 제조 방법 및 용도 |
DK1799696T3 (da) | 2004-09-17 | 2009-03-09 | Idenix Pharmaceuticals Inc | Phosphoindoler som HIV-inhibitorer |
US20060100209A1 (en) * | 2004-11-09 | 2006-05-11 | Chong-Hui Gu | Formulations of 1-(4-benzoyl-piperazin-1-yl)-2-[4-methoxy-7-(3-methyl-[1,2,4]triazol-1-yl)-1H-pyrrolo[2,3-c]pyridin-3-yl]-ethane-1,2-dione |
US20060100432A1 (en) * | 2004-11-09 | 2006-05-11 | Matiskella John D | Crystalline materials of 1-(4-benzoyl-piperazin-1-yl)-2-[4-methoxy-7-(3-methyl-[1,2,4]triazol-1-yl)-1H-pyrrolo[2,3-c]pyridin-3-yl]-ethane-1,2-dione |
US7183284B2 (en) | 2004-12-29 | 2007-02-27 | Bristol-Myers Squibb Company | Aminium salts of 1,2,3-triazoles as prodrugs of drugs including antiviral agents |
WO2006085199A1 (en) * | 2005-02-14 | 2006-08-17 | Pfizer Limited | Piperazine derivatives |
MX2007014502A (es) | 2005-05-26 | 2008-02-07 | Metabasis Therapeutics Inc | Tiromimeticos para el tratamiento de enfermedades del higado graso. |
AU2006264170A1 (en) * | 2005-06-27 | 2007-01-04 | Ambrilia Biopharma Inc. | Pyrazolo[3,4-b]pyridin-2-yl)-benzoic acid derivatives as HIV integrase inhibitors |
MX2008001292A (es) | 2005-07-29 | 2008-03-25 | Hoffmann La Roche | Nuevos derivados de indol-3-il-carbonil-piperidina y piperazina. |
US7598380B2 (en) * | 2005-08-03 | 2009-10-06 | Bristol-Myers Squibb Company | Method of preparation of azaindole derivatives |
US7851476B2 (en) * | 2005-12-14 | 2010-12-14 | Bristol-Myers Squibb Company | Crystalline forms of 1-benzoyl-4-[2-[4-methoxy-7-(3-methyl-1H-1,2,4-triazol-1-YL)-1-[(phosphonooxy)methyl]-1H-pyrrolo[2,3-C]pyridin-3-YL]-1,2-dioxoethyl]-piperazine |
US7807671B2 (en) | 2006-04-25 | 2010-10-05 | Bristol-Myers Squibb Company | Diketo-piperazine and piperidine derivatives as antiviral agents |
EP2078029B1 (en) * | 2006-09-29 | 2014-05-14 | IDENIX Pharmaceuticals, Inc. | Enantiomerically pure phosphoindole as hiv inhibitor |
TW200946541A (en) * | 2008-03-27 | 2009-11-16 | Idenix Pharmaceuticals Inc | Solid forms of an anti-HIV phosphoindole compound |
ES2535516T3 (es) | 2008-04-24 | 2015-05-12 | F2G Limited | Agentes antifúngicos de pirrol |
EP2313408B1 (en) * | 2008-06-25 | 2012-07-11 | Bristol-Myers Squibb Company | Diketopiperidine derivatives as hiv attachment inhibitors |
ES2462403T3 (es) | 2008-06-25 | 2014-05-22 | Bristol-Myers Squibb Company | Diceto azolopiperidinas y azolopiperazinas como agentes anti-VIH |
JP5638527B2 (ja) * | 2008-09-04 | 2014-12-10 | ブリストル−マイヤーズ スクイブ カンパニーBristol−Myers Squibb Company | Hiv結合阻害剤の最適な送達のための安定な医薬組成物 |
GB0817576D0 (en) * | 2008-09-25 | 2008-11-05 | Lectus Therapeutics Ltd | Calcium ion channel modulators & uses thereof |
JP6155193B2 (ja) * | 2010-11-18 | 2017-06-28 | イェール ユニバーシティーYale University | ヒト免疫不全ウイルスに対する抗体動員及び進入阻害活性を有する二官能性分子 |
WO2012142080A1 (en) | 2011-04-12 | 2012-10-18 | Bristol-Myers Squibb Company | Thioamide, amidoxime and amidrazone derivatives as hiv attachment inhibitors |
WO2013033059A1 (en) | 2011-08-29 | 2013-03-07 | Bristol-Myers Squibb Company | Spiro bicyclic diamine derivatives as hiv attachment inhibitors |
WO2013033061A1 (en) | 2011-08-29 | 2013-03-07 | Bristol-Myers Squibb Company | Fused bicyclic diamine derivatives as hiv attachment inhibitors |
US9193725B2 (en) | 2012-03-14 | 2015-11-24 | Bristol-Meyers Squibb Company | Cyclic hydrazine derivatives as HIV attachment inhibitors |
EP2895471B1 (en) | 2012-08-09 | 2016-11-23 | VIIV Healthcare UK (No.5) Limited | Piperidine amide derivatives as hiv attachment inhibitors |
EP2895472B1 (en) | 2012-08-09 | 2016-11-23 | VIIV Healthcare UK (No.5) Limited | Tricyclic alkene derivatives as HIV attachment inhibitors |
CN105229006A (zh) * | 2013-03-27 | 2016-01-06 | 百时美施贵宝公司 | 作为hiv吸附抑制剂的哌嗪和高哌嗪衍生物 |
US9586957B2 (en) * | 2013-03-27 | 2017-03-07 | VIIV Healthcare UK (No.5) Limited | 2-keto amide derivatives as HIV attachment inhibitors |
PT3221308T (pt) | 2014-11-21 | 2018-12-17 | F2G Ltd | Agentes antifúngicos |
EP3419626A1 (en) * | 2016-02-23 | 2019-01-02 | Servicio Andaluz De Salud | Piperazine derivatives as antiviral agents with increased therapeutic activity |
GB201609222D0 (en) | 2016-05-25 | 2016-07-06 | F2G Ltd | Pharmaceutical formulation |
JP2020500199A (ja) | 2016-11-21 | 2020-01-09 | バイキング・セラピューティクス・インコーポレイテッド | グリコーゲン蓄積症の治療方法 |
WO2018118838A1 (en) * | 2016-12-20 | 2018-06-28 | Biomarin Pharmaceutical Inc. | Ceramide galactosyltransferase inhibitors for the treatment of disease |
EA201992703A1 (ru) | 2017-06-05 | 2020-04-15 | Вайкинг Терапьютикс, Инк. | Композиции для лечения фиброза |
CN109154016B (zh) * | 2017-12-29 | 2021-11-16 | 邦泰生物工程(深圳)有限公司 | 一种化学-酶法制备熊去氧胆酸的方法 |
CN112135832A (zh) | 2018-03-22 | 2020-12-25 | 维京治疗公司 | 化合物的晶型和制备化合物的晶型的方法 |
CN108794559A (zh) * | 2018-07-31 | 2018-11-13 | 重庆波克底科技开发有限责任公司 | 一种以猪去氧胆酸为原料合成石胆酸的方法 |
US11819503B2 (en) | 2019-04-23 | 2023-11-21 | F2G Ltd | Method of treating coccidioides infection |
JP2023502279A (ja) * | 2019-11-22 | 2023-01-23 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | Cps1を阻害するためのピペラジン化合物 |
US20210246140A1 (en) * | 2020-01-31 | 2021-08-12 | The General Hospital Corporation | Modulators of metabotropic glutamate receptor 2 |
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GB8615562D0 (en) | 1986-06-25 | 1986-07-30 | Maggioni Farma | Aminoalcohols |
US5023265A (en) | 1990-06-01 | 1991-06-11 | Schering Corporation | Substituted 1-H-pyrrolopyridine-3-carboxamides |
DE69217224T2 (de) | 1991-07-03 | 1997-06-05 | Upjohn Co | Substituierte indole als anti-aids pharmaceutische zubereitungen |
WO1993005020A1 (en) | 1991-09-06 | 1993-03-18 | Merck & Co., Inc. | Indoles as inhibitors of hiv reverse transcriptase |
US5124327A (en) | 1991-09-06 | 1992-06-23 | Merck & Co., Inc. | HIV reverse transcriptase |
IT1265057B1 (it) | 1993-08-05 | 1996-10-28 | Dompe Spa | Tropil 7-azaindolil-3-carbossiamidi |
US5424329A (en) | 1993-08-18 | 1995-06-13 | Warner-Lambert Company | Indole-2-carboxamides as inhibitors of cell adhesion |
GB9420521D0 (en) | 1994-10-12 | 1994-11-30 | Smithkline Beecham Plc | Novel compounds |
HUP9903557A2 (en) | 1996-08-29 | 2002-08-28 | Takeda Chemical Industries Ltd | Cyclic ether compounds, producing and useing them |
US6410540B1 (en) * | 1998-08-28 | 2002-06-25 | Scios, Inc. | Inhibitors of p38-αkinase |
GB9905010D0 (en) | 1999-03-04 | 1999-04-28 | Merck Sharp & Dohme | Therapeutic agents |
US6469006B1 (en) * | 1999-06-15 | 2002-10-22 | Bristol-Myers Squibb Company | Antiviral indoleoxoacetyl piperazine derivatives |
US20020061892A1 (en) * | 2000-02-22 | 2002-05-23 | Tao Wang | Antiviral azaindole derivatives |
DK1299382T3 (da) * | 2000-07-10 | 2006-01-16 | Bristol Myers Squibb Co | Præparat og antiviral virkning af substituerede indoloxoeddikesyrepiperazinderivater |
US6573262B2 (en) * | 2000-07-10 | 2003-06-03 | Bristol-Myers Sqibb Company | Composition and antiviral activity of substituted indoleoxoacetic piperazine derivatives |
US6632810B2 (en) * | 2001-06-29 | 2003-10-14 | Kowa Co., Ltd. | Cyclic diamine compound with condensed-ring groups |
-
2002
- 2002-04-22 US US10/127,256 patent/US6825201B2/en not_active Expired - Lifetime
- 2002-04-23 WO PCT/US2002/012856 patent/WO2002085301A2/en active Application Filing
- 2002-04-23 EP EP02764315A patent/EP1381366B9/en not_active Expired - Lifetime
- 2002-04-23 MX MXPA03009680A patent/MXPA03009680A/es active IP Right Grant
- 2002-04-23 ES ES02764315T patent/ES2323859T3/es not_active Expired - Lifetime
- 2002-04-23 JP JP2002582877A patent/JP4326221B2/ja not_active Expired - Fee Related
- 2002-04-23 BR BR0209153-4A patent/BR0209153A/pt active Search and Examination
- 2002-04-23 DE DE60232065T patent/DE60232065D1/de not_active Expired - Lifetime
- 2002-04-23 PT PT02764315T patent/PT1381366E/pt unknown
- 2002-04-23 AT AT02764315T patent/ATE429229T1/de active
- 2002-04-23 DK DK02764315T patent/DK1381366T3/da active
- 2002-04-23 CA CA2445190A patent/CA2445190C/en not_active Expired - Fee Related
- 2002-04-23 CN CNB028126297A patent/CN1330307C/zh not_active Expired - Fee Related
- 2002-04-23 HU HU0401503A patent/HU230215B1/hu not_active IP Right Cessation
-
2009
- 2009-06-30 CY CY20091100690T patent/CY1109219T1/el unknown
Also Published As
Publication number | Publication date |
---|---|
ES2323859T3 (es) | 2009-07-27 |
EP1381366B9 (en) | 2009-10-21 |
HUP0401503A2 (hu) | 2004-12-28 |
HUP0401503A3 (en) | 2009-06-29 |
CA2445190A1 (en) | 2002-10-31 |
WO2002085301A2 (en) | 2002-10-31 |
BR0209153A (pt) | 2004-07-20 |
JP2004527538A (ja) | 2004-09-09 |
CN1330307C (zh) | 2007-08-08 |
JP4326221B2 (ja) | 2009-09-02 |
EP1381366B1 (en) | 2009-04-22 |
US6825201B2 (en) | 2004-11-30 |
CA2445190C (en) | 2011-08-09 |
MXPA03009680A (es) | 2004-02-12 |
US20030096825A1 (en) | 2003-05-22 |
EP1381366A4 (en) | 2005-02-16 |
EP1381366A2 (en) | 2004-01-21 |
WO2002085301A3 (en) | 2003-02-27 |
CN1520295A (zh) | 2004-08-11 |
HU230215B1 (hu) | 2015-10-28 |
DK1381366T3 (da) | 2009-08-17 |
DE60232065D1 (de) | 2009-06-04 |
CY1109219T1 (el) | 2014-07-02 |
ATE429229T1 (de) | 2009-05-15 |
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