PT1345620E - Desbridante enzimático estável de feridas - Google Patents

Desbridante enzimático estável de feridas Download PDF

Info

Publication number
PT1345620E
PT1345620E PT01962345T PT01962345T PT1345620E PT 1345620 E PT1345620 E PT 1345620E PT 01962345 T PT01962345 T PT 01962345T PT 01962345 T PT01962345 T PT 01962345T PT 1345620 E PT1345620 E PT 1345620E
Authority
PT
Portugal
Prior art keywords
wound debrider
enzymatic wound
stable enzymatic
debrider
stable
Prior art date
Application number
PT01962345T
Other languages
English (en)
Inventor
David W Hobson
David P Jones
Katarzyna Koster
Pilar P Duque
Original Assignee
Healthpoint Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Healthpoint Ltd filed Critical Healthpoint Ltd
Publication of PT1345620E publication Critical patent/PT1345620E/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/4873—Cysteine endopeptidases (3.4.22), e.g. stem bromelain, papain, ficin, cathepsin H
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dermatology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Jellies, Jams, And Syrups (AREA)
  • Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
  • Enzymes And Modification Thereof (AREA)
PT01962345T 2000-12-27 2001-08-06 Desbridante enzimático estável de feridas PT1345620E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US09/749,217 US6548556B2 (en) 2000-12-27 2000-12-27 Stable enzymatic wound debrider

Publications (1)

Publication Number Publication Date
PT1345620E true PT1345620E (pt) 2008-01-10

Family

ID=25012779

Family Applications (1)

Application Number Title Priority Date Filing Date
PT01962345T PT1345620E (pt) 2000-12-27 2001-08-06 Desbridante enzimático estável de feridas

Country Status (14)

Country Link
US (1) US6548556B2 (pt)
EP (1) EP1345620B1 (pt)
JP (1) JP4071628B2 (pt)
CN (1) CN1230200C (pt)
AT (1) ATE381941T1 (pt)
AU (1) AU2001283537B2 (pt)
CA (1) CA2433080C (pt)
DE (1) DE60132113T2 (pt)
DK (1) DK1345620T3 (pt)
ES (1) ES2296788T3 (pt)
HK (1) HK1056834A1 (pt)
MX (1) MXPA03005851A (pt)
PT (1) PT1345620E (pt)
WO (1) WO2002051436A2 (pt)

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US8658163B2 (en) 2008-03-13 2014-02-25 Curemark Llc Compositions and use thereof for treating symptoms of preeclampsia
US8084025B2 (en) 2008-04-18 2011-12-27 Curemark Llc Method for the treatment of the symptoms of drug and alcohol addiction
US9320780B2 (en) 2008-06-26 2016-04-26 Curemark Llc Methods and compositions for the treatment of symptoms of Williams Syndrome
PL2318035T3 (pl) 2008-07-01 2019-10-31 Curemark Llc Sposoby i kompozycje do leczenia objawów zaburzeń neurologicznych i zaburzeń zdrowia psychicznego
US10776453B2 (en) 2008-08-04 2020-09-15 Galenagen, Llc Systems and methods employing remote data gathering and monitoring for diagnosing, staging, and treatment of Parkinsons disease, movement and neurological disorders, and chronic pain
US20100092447A1 (en) 2008-10-03 2010-04-15 Fallon Joan M Methods and compositions for the treatment of symptoms of prion diseases
BRPI1007378A2 (pt) 2009-01-06 2020-08-18 Curemark Llc composições e métodos para o tratamento ou prevenção de infecções por staphylococcus aureus e para a erradicação ou redução de staphylococcus aureus sobre superfícies.
AU2010203714C1 (en) 2009-01-06 2013-12-12 Galenagen, Llc Compositions and methods for the treatment or the prevention of infections by e. coli
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US9056050B2 (en) 2009-04-13 2015-06-16 Curemark Llc Enzyme delivery systems and methods of preparation and use
WO2011050135A1 (en) 2009-10-21 2011-04-28 Curemark Llc Methods and compositions for the prevention and treatment of influenza
EP2509624B1 (en) 2009-12-08 2016-11-23 Smith & Nephew Orthopaedics AG Enzymatic wound debriding compositions with enhanced enzymatic activity
AU2011264489B2 (en) 2010-06-08 2013-08-15 Buckman Laboratories International, Inc. Methods to degrade sludge from pulp and paper manufacturing
AU2012245287B2 (en) 2011-04-21 2017-04-13 Curemark, Llc Compounds for the treatment of neuropsychiatric disorders
EP2707019B1 (en) 2011-05-12 2016-06-29 Smith & Nephew Orthopaedics AG Wound debridement compositions containing seaprose and methods of wound treatment using same
WO2013116732A1 (en) * 2012-02-02 2013-08-08 Curelon Llc Enzyme compositions and use thereof for wound healing
CN104602700A (zh) 2012-05-11 2015-05-06 史密夫和内修公司 蜂蜜曲霉蛋白酶在用于去除细菌生物膜的用途
US10350278B2 (en) 2012-05-30 2019-07-16 Curemark, Llc Methods of treating Celiac disease
CA2890757C (en) 2012-11-14 2021-10-26 Smith & Nephew, Inc. Stable thermolysin hydrogel
US11452698B2 (en) 2013-03-15 2022-09-27 Smith & Nephew, Inc. Dissolvable gel-forming film for delivery of active agents
EP3074026B1 (en) 2013-11-25 2020-01-08 D.T.R. Dermal Therapy Research Inc. Composition, system and method for treating skin
US10238719B2 (en) 2014-10-10 2019-03-26 Rochal Industries, Llc Compositions and kits for enzymatic debridement and methods of using the same
US20160101166A1 (en) 2014-10-10 2016-04-14 Rochal Industries, Llp Compositions and kits for treating pruritus and methods of using the same
US9592280B2 (en) 2014-10-10 2017-03-14 Rochal Industries Llc Compositions and kits for enzymatic debridement and methods of using the same
US11938173B2 (en) 2014-12-12 2024-03-26 Smith & Nephew, Inc. Use of Clostridium histolyticum protease mixture in promoting wound healing
CN105255825B (zh) * 2015-11-16 2019-07-19 广州赛莱拉干细胞科技股份有限公司 一种跟腱来源肌腱干细胞原代分离消化液及分离方法
JP6952353B2 (ja) 2016-01-31 2021-10-20 メディウーンド リミテッド 創傷を治療するためのデブリードマン組成物
BR112018071405A2 (pt) 2016-04-18 2019-02-05 Mediwound Ltd métodos de debridamento de ferimentos crônicos
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EP3573622B1 (en) 2017-01-30 2023-10-18 Smith & Nephew, Inc. Synergistic combination of thermolysin and an antibacterial agent to reduce or eliminate bacterial biofilms from surfaces
CN106902075A (zh) * 2017-02-23 2017-06-30 任君刚 一种基于无水技术的水敏感粘附性软膏及其制备方法
CN110180019A (zh) * 2019-07-11 2019-08-30 周玉芳 一种提高皮肤修复功能的复合酶及其制备方法
US11541009B2 (en) 2020-09-10 2023-01-03 Curemark, Llc Methods of prophylaxis of coronavirus infection and treatment of coronaviruses

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Also Published As

Publication number Publication date
ATE381941T1 (de) 2008-01-15
US6548556B2 (en) 2003-04-15
CA2433080A1 (en) 2002-07-04
US20020114798A1 (en) 2002-08-22
DE60132113T2 (de) 2008-12-18
JP4071628B2 (ja) 2008-04-02
HK1056834A1 (en) 2004-03-05
CA2433080C (en) 2004-07-06
JP2004520321A (ja) 2004-07-08
AU2001283537B2 (en) 2005-04-14
CN1494431A (zh) 2004-05-05
MXPA03005851A (es) 2004-05-04
WO2002051436A2 (en) 2002-07-04
CN1230200C (zh) 2005-12-07
DK1345620T3 (da) 2008-05-13
ES2296788T3 (es) 2008-05-01
DE60132113D1 (de) 2008-02-07
WO2002051436A3 (en) 2002-10-03
EP1345620B1 (en) 2007-12-26
EP1345620A2 (en) 2003-09-24

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