PT1319651E - Composto 2-aminopropano-1,3-diol, sua utilizacao farmaceutica e seus intermediarios sinteticos - Google Patents
Composto 2-aminopropano-1,3-diol, sua utilizacao farmaceutica e seus intermediarios sinteticosInfo
- Publication number
- PT1319651E PT1319651E PT03003623T PT03003623T PT1319651E PT 1319651 E PT1319651 E PT 1319651E PT 03003623 T PT03003623 T PT 03003623T PT 03003623 T PT03003623 T PT 03003623T PT 1319651 E PT1319651 E PT 1319651E
- Authority
- PT
- Portugal
- Prior art keywords
- compound
- pharmaceutical
- aminopropane
- diol
- drug
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
- C07C255/01—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms
- C07C255/16—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms containing cyano groups and singly-bound oxygen atoms bound to the same carbon atom of an acyclic carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C225/00—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones
- C07C225/02—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to acyclic carbon atoms of the carbon skeleton
- C07C225/14—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being unsaturated
- C07C225/16—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
- C07C215/02—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C215/22—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated
- C07C215/28—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings
- C07C215/34—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings containing hydroxy groups and carbon atoms of six-membered aromatic rings bound to the same carbon atom of the carbon skeleton and at least one hydroxy group bound to another carbon atom of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C223/00—Compounds containing amino and —CHO groups bound to the same carbon skeleton
- C07C223/02—Compounds containing amino and —CHO groups bound to the same carbon skeleton having amino groups bound to acyclic carbon atoms of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic System
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1804—Compounds having Si-O-C linkages
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP8625597 | 1997-04-04 |
Publications (1)
Publication Number | Publication Date |
---|---|
PT1319651E true PT1319651E (pt) | 2005-09-30 |
Family
ID=13881722
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT98911211T PT1002792E (pt) | 1997-04-04 | 1998-04-03 | Compostos de 2-aminopropano-1,3-diol, sua utilizacao medicinal e intermediariosda sintese dos mesmos |
PT03003623T PT1319651E (pt) | 1997-04-04 | 1998-04-03 | Composto 2-aminopropano-1,3-diol, sua utilizacao farmaceutica e seus intermediarios sinteticos |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT98911211T PT1002792E (pt) | 1997-04-04 | 1998-04-03 | Compostos de 2-aminopropano-1,3-diol, sua utilizacao medicinal e intermediariosda sintese dos mesmos |
Country Status (18)
Country | Link |
---|---|
US (2) | USRE39072E1 (pt) |
EP (2) | EP1319651B1 (pt) |
JP (1) | JP4045364B2 (pt) |
KR (1) | KR100551931B1 (pt) |
CN (2) | CN1137086C (pt) |
AT (2) | ATE298740T1 (pt) |
AU (1) | AU735853B2 (pt) |
BR (1) | BR9808481A (pt) |
CA (1) | CA2286315C (pt) |
DE (2) | DE69825056T2 (pt) |
DK (2) | DK1002792T3 (pt) |
ES (2) | ES2240868T3 (pt) |
IL (3) | IL132208A (pt) |
NZ (1) | NZ500713A (pt) |
PT (2) | PT1002792E (pt) |
RU (1) | RU2198162C2 (pt) |
SI (2) | SI1002792T1 (pt) |
WO (1) | WO1998045249A1 (pt) |
Families Citing this family (71)
Publication number | Priority date | Publication date | Assignee | Title |
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US6861442B1 (en) * | 1998-12-30 | 2005-03-01 | Sugen, Inc. | PYK2 and inflammation |
US6515117B2 (en) * | 1999-10-12 | 2003-02-04 | Bristol-Myers Squibb Company | C-aryl glucoside SGLT2 inhibitors and method |
WO2002006268A1 (fr) | 2000-07-13 | 2002-01-24 | Sankyo Company, Limited | Derives d'alcool amino |
AU2001296536A1 (en) | 2000-10-03 | 2002-04-15 | University Of Virginian Patent Foundation | Novel lysophosphatidic acid receptor agonists and antagonists |
US20040241211A9 (en) * | 2000-11-06 | 2004-12-02 | Fischell Robert E. | Devices and methods for reducing scar tissue formation |
US6534693B2 (en) * | 2000-11-06 | 2003-03-18 | Afmedica, Inc. | Surgically implanted devices having reduced scar tissue formation |
US7064217B2 (en) | 2001-01-30 | 2006-06-20 | University Of Virginia Patent Foundation | Agonists and antagonists of sphingosine-1-phosphate receptors |
WO2002067915A1 (en) * | 2001-02-22 | 2002-09-06 | Novartis Ag | Use of accelerated lymphocyte homing agents for the manufacture of a medicament for the treatment of delayed graft function |
US20030072717A1 (en) * | 2001-02-23 | 2003-04-17 | Vapotronics, Inc. | Inhalation device having an optimized air flow path |
CZ20032560A3 (cs) | 2001-03-26 | 2003-12-17 | Novartis Ag | Deriváty 2-aminopropanolu, způsob jejich přípravy a farmaceutický prostředek, který je obsahuje |
JP5342730B2 (ja) * | 2001-05-21 | 2013-11-13 | インジェット デジタル エアロソルズ リミテッド | 経肺経路を介するタンパク質送達のための組成物 |
GB0117921D0 (en) * | 2001-07-23 | 2001-09-12 | Novartis Ag | Organic compounds |
WO2003029184A1 (fr) * | 2001-09-27 | 2003-04-10 | Kyorin Pharmaceutical Co., Ltd. | Derive d'ether de diaryle, son sel d'addition et son immunosuppresseur |
JP4217620B2 (ja) | 2001-09-27 | 2009-02-04 | 杏林製薬株式会社 | ジアリールスルフィド誘導体とその付加塩及び免疫抑制剤 |
GB0125443D0 (en) * | 2001-10-23 | 2001-12-12 | Novartis Ag | Organic Compounds |
AU2003202495B2 (en) * | 2002-01-11 | 2006-07-20 | Sankyo Company, Limited | Amino alcohol derivative or phosphonic acid derivative and medicinal composition containing these |
US6797722B2 (en) * | 2002-05-03 | 2004-09-28 | Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. | Use of 3-(2-ethylphenyl)-5-(3-methoxyphenyl)-1H-1,2,4-triazole for the treatment of autoimmune diseases |
EP1944026B1 (en) | 2002-05-16 | 2013-06-26 | Novartis AG | Use of EDG receptor binding agents in cancer |
GB0217152D0 (en) * | 2002-07-24 | 2002-09-04 | Novartis Ag | Organic compounds |
CA2497067A1 (en) | 2002-09-13 | 2004-03-25 | Novartis Ag | Amino-propanol derivatives |
WO2004028521A2 (en) * | 2002-09-24 | 2004-04-08 | Novartis Ag | Sphingosine-1-phosphate receptor agonists in the treatment of demyelinating disorders |
AU2008200368B2 (en) * | 2003-04-08 | 2011-04-28 | Mitsubishi Tanabe Pharma Corporation | Solid pharmaceutical compositions comprising a S1P receptor agonist and a sugar alcohol |
MXPA05010860A (es) * | 2003-04-08 | 2006-05-25 | Novartis Ag | Composiciones solidas farmaceuticas que comprenden un agonista de receptor sip y y un alcohol de azucar. |
AU2011205050B2 (en) * | 2003-04-08 | 2014-01-30 | Mitsubishi Tanabe Pharma Corporation | Solid pharmaceutical compositions comprising a S1P receptor agonist and a sugar alcohol |
ATE547395T1 (de) * | 2003-04-30 | 2012-03-15 | Novartis Pharma Gmbh | Aminopropanol-derivate als modulatoren des sphingosin-1-phosphat-rezeptors |
MY150088A (en) | 2003-05-19 | 2013-11-29 | Irm Llc | Immunosuppressant compounds and compositions |
US7524887B2 (en) | 2003-06-06 | 2009-04-28 | Sanofi-Aventis Deutschland Gmbh | 2-amino-1,3-propanediol compounds for the treatment of acute pain |
EP1484057A1 (en) * | 2003-06-06 | 2004-12-08 | Aventis Pharma Deutschland GmbH | Use of 2-amino-1-3-propanediol derivatives for the manufacture of a medicament for the treatment of various types of pain |
US20040265238A1 (en) * | 2003-06-27 | 2004-12-30 | Imtiaz Chaudry | Inhalable formulations for treating pulmonary hypertension and methods of using same |
GB0320638D0 (en) | 2003-09-03 | 2003-10-01 | Novartis Ag | Organic compounds |
GB0324210D0 (en) | 2003-10-15 | 2003-11-19 | Novartis Ag | Organic compounds |
GB0329498D0 (en) | 2003-12-19 | 2004-01-28 | Novartis Ag | Organic compounds |
GB0500020D0 (en) | 2005-01-04 | 2005-02-09 | Novartis Ag | Organic compounds |
TWI355934B (en) | 2004-02-24 | 2012-01-11 | Sankyo Co | Pharmaceutical composition for treatment or prophy |
JP2007536310A (ja) * | 2004-05-03 | 2007-12-13 | ノバルティス アクチエンゲゼルシャフト | S1p受容体アゴニストおよびjak3キナーゼ阻害剤を含む、組合せ剤 |
US7820703B2 (en) | 2004-05-06 | 2010-10-26 | University Of Virginia Patent Foundation | Lysophosphatidic acid receptor selective antagonists |
GB0411929D0 (en) * | 2004-05-27 | 2004-06-30 | Novartis Ag | Organic compounds |
CA2571710A1 (en) | 2004-06-24 | 2006-11-02 | Nicholas Valiante | Small molecule immunopotentiators and assays for their detection |
ATE502630T1 (de) * | 2004-07-16 | 2011-04-15 | Kyorin Seiyaku Kk | Verfahren zur effektiven anwendung eines medikaments und verfahren zur prävention von nebenwirkungen |
JP4919374B2 (ja) * | 2004-07-29 | 2012-04-18 | 第一三共株式会社 | 免疫抑制剤としての医薬組成物 |
TW200611687A (en) * | 2004-07-29 | 2006-04-16 | Sankyo Co | Pharmaceutical compositions used for immunosuppressant |
US20080096972A1 (en) | 2004-07-30 | 2008-04-24 | Thitiwan Buranachokpaisan | Compound formulations of 2-amino-1, 3-propanediol compounds |
US20060223866A1 (en) * | 2004-08-13 | 2006-10-05 | Praecis Pharmaceuticals, Inc. | Methods and compositions for modulating sphingosine-1-phosphate (S1P) receptor activity |
AU2005272619A1 (en) * | 2004-08-13 | 2006-02-23 | Praecis Pharmaceuticals, Inc. | Methods and compositions for modulating sphingosine-1-phosphate (SIP) receptor activity |
RU2376285C2 (ru) * | 2004-10-12 | 2009-12-20 | Киорин Фармасьютикал Ко., Лтд. | Процесс получения гидрохлорида 2-амино-2-[2-[4-(3-бензилоксифенилтио)-2-хлорфенилэтил]-1,3-пропандиола] и его гидратов, а также промежуточные продукты их получения |
WO2006058316A1 (en) | 2004-11-29 | 2006-06-01 | Novartis Ag | Dosage regimen of an s1p receptor agonist |
BRPI0607740A2 (pt) * | 2005-02-08 | 2009-09-29 | Novartis Ag | indução de anticorpos antilinfócitos |
GB0504544D0 (en) | 2005-03-04 | 2005-04-13 | Novartis Ag | Organic compounds |
TW200702326A (en) * | 2005-05-31 | 2007-01-16 | Mitsubishi Pharma Corp | 2-aminobutanol compound and its pharmaceutical use |
TWI418350B (zh) * | 2005-06-24 | 2013-12-11 | Sankyo Co | 含有ppar調節劑之醫藥組成物的用途 |
GT200600350A (es) * | 2005-08-09 | 2007-03-28 | Formulaciones líquidas | |
RU2421214C2 (ru) * | 2005-10-07 | 2011-06-20 | Киорин Фармасьютикал Ко., Лтд. | Терапевтическое средство для лечения гепатита и способ лечения гепатита |
TWI389683B (zh) * | 2006-02-06 | 2013-03-21 | Kyorin Seiyaku Kk | A therapeutic agent for an inflammatory bowel disease or an inflammatory bowel disease treatment using a 2-amino-1,3-propanediol derivative as an active ingredient |
US7825152B2 (en) | 2006-04-11 | 2010-11-02 | Novartis Ag | Organic compounds and their uses |
GB0612721D0 (en) | 2006-06-27 | 2006-08-09 | Novartis Ag | Organic compounds |
TW200815600A (en) | 2006-08-04 | 2008-04-01 | Daiichi Sankyo Co Ltd | An enzyme for phosphorizing a medicine |
SG174029A1 (en) * | 2006-08-08 | 2011-09-29 | Kyorin Seiyaku Kk | Aminoalcohol derivative and immunosuppressant containing the same as active ingredient |
MY152176A (en) * | 2006-08-08 | 2014-08-15 | Kyorin Seiyaku Kk | Amino phosphate derivative and s1p receptor modulator having same as an active ingredient |
KR101884047B1 (ko) | 2006-09-26 | 2018-07-31 | 노파르티스 아게 | S1p 조정제를 포함하는 제약 조성물 |
WO2008121709A1 (en) * | 2007-03-30 | 2008-10-09 | Transport Pharmaceuticals, Inc. | Pharmaceutical formulations for iontophoretic delivery of an anti-fungal drug |
MX2009013730A (es) | 2007-06-14 | 2010-01-26 | Mitsubishi Tanabe Pharma Corp | Compuesto amina y uso farmaceutico del mismo. |
DE102007039954A1 (de) * | 2007-08-23 | 2009-02-26 | Henkel Ag & Co. Kgaa | Reduktive Entfärbung keratinhaltiger Fasern |
PL2952177T3 (pl) | 2007-10-12 | 2021-07-19 | Novartis Ag | Kompozycje zawierające modulatory receptora fosforanu sfingozyny 1 (s1p) |
JP5452237B2 (ja) | 2008-02-07 | 2014-03-26 | 杏林製薬株式会社 | アミノアルコール誘導体を有効成分とする炎症性腸疾患の治療剤又は予防剤 |
US20110182850A1 (en) | 2009-04-10 | 2011-07-28 | Trixi Brandl | Organic compounds and their uses |
US8512690B2 (en) | 2009-04-10 | 2013-08-20 | Novartis Ag | Derivatised proline containing peptide compounds as protease inhibitors |
CA2811799A1 (en) | 2010-10-08 | 2012-04-12 | Novartis Ag | Vitamin e formulations of sulfamide ns3 inhibitors |
AR085749A1 (es) | 2011-04-01 | 2013-10-23 | Novartis Ag | Formulaciones |
EP2842937B1 (en) | 2012-04-23 | 2018-01-17 | Mitsubishi Tanabe Pharma Corporation | Amine compound and use thereof for medical purposes |
CN110862409B (zh) * | 2019-12-04 | 2021-08-20 | 江南大学 | 一种制备含二元醇结构的硅烷类化合物及其改性水性聚氨酯的方法 |
US20220153684A1 (en) * | 2020-11-13 | 2022-05-19 | Shivalik Rasayan Limited | Process for preparation of fingolimod hydrochloride |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3660488A (en) | 1965-07-16 | 1972-05-02 | Phillips Petroleum Co | 2-halo-alkylene- and -cyclopentylene-2-amino-propane 1 3-diols |
ATE172711T1 (de) * | 1992-10-21 | 1998-11-15 | Yoshitomi Pharmaceutical | 2-amino-1, 3- propandiolverbindung und immunosuppressium |
DE69524962D1 (de) * | 1994-08-22 | 2002-02-14 | Welfide Corp | Benzolderivate und deren medizinische verwendung |
-
1998
- 1998-04-03 SI SI9830698T patent/SI1002792T1/xx unknown
- 1998-04-03 PT PT98911211T patent/PT1002792E/pt unknown
- 1998-04-03 US US10/410,387 patent/USRE39072E1/en not_active Expired - Lifetime
- 1998-04-03 ES ES03003623T patent/ES2240868T3/es not_active Expired - Lifetime
- 1998-04-03 AU AU65230/98A patent/AU735853B2/en not_active Ceased
- 1998-04-03 AT AT03003623T patent/ATE298740T1/de active
- 1998-04-03 KR KR1019997009082A patent/KR100551931B1/ko not_active IP Right Cessation
- 1998-04-03 CN CNB988058804A patent/CN1137086C/zh not_active Expired - Fee Related
- 1998-04-03 DK DK98911211T patent/DK1002792T3/da active
- 1998-04-03 NZ NZ500713A patent/NZ500713A/xx not_active IP Right Cessation
- 1998-04-03 PT PT03003623T patent/PT1319651E/pt unknown
- 1998-04-03 EP EP03003623A patent/EP1319651B1/en not_active Expired - Lifetime
- 1998-04-03 IL IL13220898A patent/IL132208A/xx not_active IP Right Cessation
- 1998-04-03 JP JP54259298A patent/JP4045364B2/ja not_active Expired - Fee Related
- 1998-04-03 IL IL15506698A patent/IL155066A/en not_active IP Right Cessation
- 1998-04-03 US US09/402,375 patent/US6214873B1/en not_active Ceased
- 1998-04-03 BR BR9808481-0A patent/BR9808481A/pt active Search and Examination
- 1998-04-03 DE DE69825056T patent/DE69825056T2/de not_active Expired - Lifetime
- 1998-04-03 DE DE69830756T patent/DE69830756T2/de not_active Expired - Lifetime
- 1998-04-03 AT AT98911211T patent/ATE271028T1/de active
- 1998-04-03 EP EP98911211A patent/EP1002792B1/en not_active Expired - Lifetime
- 1998-04-03 CN CNB03136893XA patent/CN1290819C/zh not_active Expired - Fee Related
- 1998-04-03 CA CA002286315A patent/CA2286315C/en not_active Expired - Fee Related
- 1998-04-03 ES ES98911211T patent/ES2226110T3/es not_active Expired - Lifetime
- 1998-04-03 WO PCT/JP1998/001571 patent/WO1998045249A1/ja active IP Right Grant
- 1998-04-03 DK DK03003623T patent/DK1319651T3/da active
- 1998-04-03 IL IL15506598A patent/IL155065A/en not_active IP Right Cessation
- 1998-04-03 RU RU99123047/04A patent/RU2198162C2/ru not_active IP Right Cessation
- 1998-04-03 SI SI9830785T patent/SI1319651T1/xx unknown
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