PT1289945E - Derivados dissulfureto de anilina para o tratamento de doencas alergicas - Google Patents

Derivados dissulfureto de anilina para o tratamento de doencas alergicas

Info

Publication number
PT1289945E
PT1289945E PT01930719T PT01930719T PT1289945E PT 1289945 E PT1289945 E PT 1289945E PT 01930719 T PT01930719 T PT 01930719T PT 01930719 T PT01930719 T PT 01930719T PT 1289945 E PT1289945 E PT 1289945E
Authority
PT
Portugal
Prior art keywords
allergic diseases
dissulfuret
aniline
derivatives
treatment
Prior art date
Application number
PT01930719T
Other languages
English (en)
Portuguese (pt)
Inventor
Steven T Miller
Mark R Hellberg
Zixia Feng
Original Assignee
Alcon Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alcon Inc filed Critical Alcon Inc
Publication of PT1289945E publication Critical patent/PT1289945E/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/165Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/23Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C323/39Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton at least one of the nitrogen atoms being part of any of the groups, X being a hetero atom, Y being any atom
    • C07C323/43Y being a hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/165Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/325Carbamic acids; Thiocarbamic acids; Anhydrides or salts thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/02Nasal agents, e.g. decongestants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/14Decongestants or antiallergics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/16Otologicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/23Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C323/39Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton at least one of the nitrogen atoms being part of any of the groups, X being a hetero atom, Y being any atom
    • C07C323/40Y being a hydrogen or a carbon atom
    • C07C323/41Y being a hydrogen or an acyclic carbon atom

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Immunology (AREA)
  • Otolaryngology (AREA)
  • Dermatology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
PT01930719T 2000-05-19 2001-04-25 Derivados dissulfureto de anilina para o tratamento de doencas alergicas PT1289945E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US20574600P 2000-05-19 2000-05-19

Publications (1)

Publication Number Publication Date
PT1289945E true PT1289945E (pt) 2004-10-29

Family

ID=22763478

Family Applications (1)

Application Number Title Priority Date Filing Date
PT01930719T PT1289945E (pt) 2000-05-19 2001-04-25 Derivados dissulfureto de anilina para o tratamento de doencas alergicas

Country Status (19)

Country Link
US (2) US6372802B2 (enExample)
EP (1) EP1289945B1 (enExample)
JP (1) JP2003534317A (enExample)
KR (1) KR20020093982A (enExample)
CN (1) CN1173697C (enExample)
AR (1) AR028565A1 (enExample)
AT (1) ATE272619T1 (enExample)
AU (2) AU2001257227B2 (enExample)
BR (1) BR0110845A (enExample)
CA (1) CA2408145A1 (enExample)
DE (1) DE60104690T2 (enExample)
DK (1) DK1289945T3 (enExample)
ES (1) ES2222370T3 (enExample)
MX (1) MXPA02011480A (enExample)
PL (1) PL365459A1 (enExample)
PT (1) PT1289945E (enExample)
TR (1) TR200402299T4 (enExample)
WO (1) WO2001090059A1 (enExample)
ZA (1) ZA200208839B (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001045668A2 (en) * 1999-12-20 2001-06-28 Schering Corporation Stable extended release oral dosage composition comprising pseudoephedrine and desloratadine
WO2001045676A2 (en) * 1999-12-20 2001-06-28 Schering Corporation Extended release oral dosage composition
UA82323C2 (uk) * 2002-08-09 2008-04-10 Меда Фарма Гмбх & Ко. Кг Нова комбінація глюкокортикоїду та pde-інгібітору для лікування респіраторних захворювань, алергічних захворювань, астми та хронічних обструктивних легеневих захворювань
WO2006076027A2 (en) * 2004-05-17 2006-07-20 Cambrios Technology Corp. Biofabrication of transistors including field effect transistors
ZA200610350B (en) * 2004-06-28 2008-12-31 Alcon Inc Topical formulations for treating allergic diseases
US20130304180A1 (en) * 2012-05-09 2013-11-14 Michael L. Green Catheter having dual balloon hydraulic actuator
US11058444B2 (en) 2017-12-11 2021-07-13 Covidien Lp Electrically enhanced retrieval of material from vessel lumens

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1232787A (enExample) 1967-08-08 1971-05-19
US3663616A (en) 1969-10-13 1972-05-16 Sherwin Williams Co Bis(2-carbamylphenyl)disulfides
EP0006227B1 (en) 1978-06-16 1984-12-27 Kyowa Hakko Kogyo Co., Ltd Antithrombotic pharmaceutical preparation containing 2,2'-dithiobis benzamide derivatives and new 2,2'-dithiobis benzamide derivatives
JPS59205356A (ja) * 1983-05-10 1984-11-20 Teikoku Hormone Mfg Co Ltd ジスルフアニルベンゼン酢酸誘導体
GB8520662D0 (en) 1985-08-17 1985-09-25 Wellcome Found Tricyclic aromatic compounds
US4923892A (en) 1985-08-17 1990-05-08 Burroughs Wellcome Co. Tricyclic aromatic compounds
JPS6310784A (ja) 1986-03-03 1988-01-18 Kyowa Hakko Kogyo Co Ltd 抗アレルギー剤
GB9020933D0 (en) 1990-09-26 1990-11-07 Ici Plc Compound,preparation and use
US5859017A (en) 1994-04-01 1999-01-12 Cell Therapeutics, Inc. Method for inhibiting mast cell and basophil activation
US5734081A (en) 1994-08-05 1998-03-31 Warner-Lambert Company Arylthio compounds
US5463122A (en) 1994-08-05 1995-10-31 Warner-Lambert Company Arylthio compounds
US6001555A (en) 1994-09-23 1999-12-14 The United States Of America As Represented By The Department Of Health And Human Services Method for identifying and using compounds that inactivate HIV-1 and other retroviruses by attacking highly conserved zinc fingers in the viral nucleocapsid protein
JPH08253454A (ja) * 1994-12-26 1996-10-01 Nisshin Flour Milling Co Ltd ジフェニルジスルフィド化合物
JPH095926A (ja) 1995-04-18 1997-01-10 Fuji Photo Film Co Ltd 熱現像感光材料
US5641805A (en) 1995-06-06 1997-06-24 Alcon Laboratories, Inc. Topical ophthalmic formulations for treating allergic eye diseases
WO1997038693A1 (en) 1996-04-18 1997-10-23 Alcon Laboratories, Inc. Calcium channel blockers as human conjunctival mast cell degranulation inhibitors for treating ocular allergic conditions
JP2894445B2 (ja) 1997-02-12 1999-05-24 日本たばこ産業株式会社 Cetp活性阻害剤として有効な化合物
JP3940201B2 (ja) 1997-05-20 2007-07-04 大塚製薬株式会社 3,3’−ジチオジベンゾヒドロキサム酸
JP3702382B2 (ja) * 1997-10-22 2005-10-05 参天製薬株式会社 NF−κB活性化阻害剤
DK1282599T3 (da) * 2000-05-19 2006-07-31 Alcon Inc Disulfidderivater, der er egnede til behandling af allergiske sygdomme
MXPA02011482A (es) * 2000-05-19 2003-06-06 Alcon Inc Composiciones que contienen un derivado de disulfuro de benzamida para tratar enfermedades.
JP2002193796A (ja) * 2000-12-27 2002-07-10 Ajinomoto Co Inc 炎症因子活性化抑制剤、その用途及びそのために使用可能な新規ポリスルフィド誘導体

Also Published As

Publication number Publication date
CN1173697C (zh) 2004-11-03
US20020013311A1 (en) 2002-01-31
CA2408145A1 (en) 2001-11-29
US6372802B2 (en) 2002-04-16
AR028565A1 (es) 2003-05-14
BR0110845A (pt) 2003-02-11
KR20020093982A (ko) 2002-12-16
EP1289945A1 (en) 2003-03-12
TR200402299T4 (tr) 2004-12-21
ES2222370T3 (es) 2005-02-01
AU2001257227B2 (en) 2005-04-07
HK1050677A1 (en) 2003-07-04
JP2003534317A (ja) 2003-11-18
ZA200208839B (en) 2004-02-03
PL365459A1 (en) 2005-01-10
WO2001090059A1 (en) 2001-11-29
DE60104690D1 (de) 2004-09-09
DE60104690T2 (de) 2005-01-13
CN1429208A (zh) 2003-07-09
EP1289945B1 (en) 2004-08-04
ATE272619T1 (de) 2004-08-15
US6452052B1 (en) 2002-09-17
DK1289945T3 (da) 2004-11-01
US20020115658A1 (en) 2002-08-22
AU5722701A (en) 2001-12-03
MXPA02011480A (es) 2003-06-06

Similar Documents

Publication Publication Date Title
BRPI0418245A (pt) nitróxi-derivados de prostaglandina
CA2447924A1 (en) Olopatadine formulations for topical administration
NO20075660L (no) Blanding for behandling av inflammatoriske sykdommer
DE602006006308D1 (de) Suspensionsformulierungen mit einem aktiven wirkstoff, einem poloxamer- oder meroxapol-tensid und einem glycol und ihre verwendung zur herstellung eines medikaments zur behandlung von augenkrankheiten
EP1797881A4 (en) MEDICAL COMPOSITION
BR9808581A (pt) Estabilização de benzimidazóis sensìveis a ácido com combinações de aminoácido/ciclodextrina
UA107653C2 (en) Extract of aerial parts of oats harvested before ear emergence
BR0212898A (pt) Método de tratamento de infecções do ouvido médio
BRPI0812494A2 (pt) Derivados de 3',4',5-trimetóxi como estimulante da secreção de muco, método de preparação do mesmo, e composição farmacêutica compreendendo o mesmo
EP2359832A3 (en) Therapeutic agents targeting the NCCA-ATP channel and methods of use thereof
SE9704644D0 (sv) New use
PT1556371E (pt) Derivados de benzimidazole e sua utilizacao como pro-farmacos de inibadores da bomba de protoes.
BR0013793A (pt) Medicamentos profiláticos e terapêuticos para doenças oftálmicas
PT1289945E (pt) Derivados dissulfureto de anilina para o tratamento de doencas alergicas
EA200602092A1 (ru) Способ и композиция для лечения ринита
CY1109666T1 (el) Μεθοδος θεραπειας διαταραχων ξηροφθαλμιας και ραγοειδιτιδας
NO20065662L (no) Esterlinkede makrolider nyttige for behandlingen av mikrobielle infeksjoner
MXPA02011482A (es) Composiciones que contienen un derivado de disulfuro de benzamida para tratar enfermedades.
WO2001034129A3 (en) Heteroatom-interrupted analogs of 15-hydroxyeicosatetraenoic acid and methods of use
CY1105164T1 (el) Παραγωγα δισουλφιδιου χρησιμα για θepαπεια αλλepγικων ασθενειων
DE60217292D1 (de) Veterinärmedizinische dermatologische zusammensetzung
DE60003074D1 (de) Fusidinsäure-derivate
NO20064196L (no) Utvortes preparat for behandling av smertefulle hudskader
WO2007057756B1 (en) Isocystene derivatives for the treatment of pain
WO2007131488A3 (de) Verwendung von chinolonderivaten als anti-protozoäre mittel und in kombinatinonspräparaten