CY1105164T1 - Παραγωγα δισουλφιδιου χρησιμα για θepαπεια αλλepγικων ασθενειων - Google Patents

Παραγωγα δισουλφιδιου χρησιμα για θepαπεια αλλepγικων ασθενειων

Info

Publication number
CY1105164T1
CY1105164T1 CY20061101174T CY061101174T CY1105164T1 CY 1105164 T1 CY1105164 T1 CY 1105164T1 CY 20061101174 T CY20061101174 T CY 20061101174T CY 061101174 T CY061101174 T CY 061101174T CY 1105164 T1 CY1105164 T1 CY 1105164T1
Authority
CY
Cyprus
Prior art keywords
treatment
diseases
allepic
derivatives useful
disulphide derivatives
Prior art date
Application number
CY20061101174T
Other languages
English (en)
Inventor
Zixia Feng
Mark R. Hellberg
Steven T. Miller
Original Assignee
Alcon, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alcon, Inc. filed Critical Alcon, Inc.
Publication of CY1105164T1 publication Critical patent/CY1105164T1/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C323/39—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton at least one of the nitrogen atoms being part of any of the groups, X being a hetero atom, Y being any atom
    • C07C323/43—Y being a hetero atom
    • C07C323/44—X or Y being nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/04—Antipruritics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/14—Decongestants or antiallergics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pulmonology (AREA)
  • Dermatology (AREA)
  • Obesity (AREA)
  • Child & Adolescent Psychology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Immunology (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Παράγωγα διφαινυλ δισουλφιδίου του τύπου (I) όπου το Χ είναι -NHC( = 0)NH-R και το R είναι ως ορίζεται στις αξιώσεις, είναι χρήσιμα για πρόληψη ή θεραπεία αλλεργικών ασθενειών του οφθαλμού, ρινός, δέρματος, ωτός, γαστροεντερικής οδού, αεροδών ή πνεύμονα και αποτροπής ή θεραπείας εκδηλώσεων συστημικής βασεοφιλοκυττάρωσης. Τα παράγωγα δισουλφιδίου δρουν ως σταθεροποιητές βασεόφιλου κυττάρου.
CY20061101174T 2000-05-19 2006-08-23 Παραγωγα δισουλφιδιου χρησιμα για θepαπεια αλλepγικων ασθενειων CY1105164T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US20582700P 2000-05-19 2000-05-19
PCT/US2001/013331 WO2001090060A1 (en) 2000-05-19 2001-04-25 Disulfide derivatives useful for treating allergic diseases

Publications (1)

Publication Number Publication Date
CY1105164T1 true CY1105164T1 (el) 2010-03-03

Family

ID=22763799

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20061101174T CY1105164T1 (el) 2000-05-19 2006-08-23 Παραγωγα δισουλφιδιου χρησιμα για θepαπεια αλλepγικων ασθενειων

Country Status (20)

Country Link
US (3) US6492552B2 (el)
EP (1) EP1282599B1 (el)
JP (1) JP2003534318A (el)
KR (1) KR20030007589A (el)
CN (2) CN1241912C (el)
AR (1) AR028566A1 (el)
AT (1) ATE330938T1 (el)
AU (2) AU2001255675B2 (el)
BR (1) BR0110943A (el)
CA (1) CA2407964A1 (el)
CY (1) CY1105164T1 (el)
DE (1) DE60120961T2 (el)
DK (1) DK1282599T3 (el)
ES (1) ES2261402T3 (el)
HK (1) HK1050185A1 (el)
MX (1) MXPA02011481A (el)
PL (1) PL365457A1 (el)
PT (1) PT1282599E (el)
WO (1) WO2001090060A1 (el)
ZA (1) ZA200208840B (el)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR0110845A (pt) * 2000-05-19 2003-02-11 Alcon Inc Derivados de dissulfeto de anilina para o tratamento de doenças alérgicas
AU2003259007A1 (en) 2002-10-31 2004-05-25 Amersham Biosciences Ab Use of urea variants as affinity ligands
AU2005259911A1 (en) * 2004-06-28 2006-01-12 Alcon, Inc. Topical formulations for treating allergic diseases
EP1841808B1 (en) * 2004-12-22 2009-01-21 California Institute Of Technology Degradable p0lymers and methods of preparation thereof
EP2720712B1 (en) * 2011-06-17 2016-03-02 Halozyme, Inc. Stable formulations of a hyaluronan-degrading enzyme
US20130011378A1 (en) 2011-06-17 2013-01-10 Tzung-Horng Yang Stable formulations of a hyaluronan-degrading enzyme
FR3057264B1 (fr) 2016-10-12 2020-05-29 Arkema France Composes porteurs de groupes associatifs azotes
CN108586299B (zh) * 2018-06-06 2020-06-16 北京化工大学 一种可引发、聚合及降低体积收缩的芳香二硫化合物的制备方法及用途

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1232787A (el) 1967-08-08 1971-05-19
US3663616A (en) 1969-10-13 1972-05-16 Sherwin Williams Co Bis(2-carbamylphenyl)disulfides
DE2967337D1 (en) * 1978-06-16 1985-02-07 Kyowa Hakko Kogyo Kk Antithrombotic pharmaceutical preparation containing 2,2'-dithiobis benzamide derivatives and new 2,2'-dithiobis benzamide derivatives
GB8520662D0 (en) 1985-08-17 1985-09-25 Wellcome Found Tricyclic aromatic compounds
US4923892A (en) 1985-08-17 1990-05-08 Burroughs Wellcome Co. Tricyclic aromatic compounds
JPS6310784A (ja) 1986-03-03 1988-01-18 Kyowa Hakko Kogyo Co Ltd 抗アレルギー剤
GB9020933D0 (en) 1990-09-26 1990-11-07 Ici Plc Compound,preparation and use
US5859017A (en) 1994-04-01 1999-01-12 Cell Therapeutics, Inc. Method for inhibiting mast cell and basophil activation
US5734081A (en) 1994-08-05 1998-03-31 Warner-Lambert Company Arylthio compounds
US5463122A (en) 1994-08-05 1995-10-31 Warner-Lambert Company Arylthio compounds
US6001555A (en) 1994-09-23 1999-12-14 The United States Of America As Represented By The Department Of Health And Human Services Method for identifying and using compounds that inactivate HIV-1 and other retroviruses by attacking highly conserved zinc fingers in the viral nucleocapsid protein
JPH095926A (ja) * 1995-04-18 1997-01-10 Fuji Photo Film Co Ltd 熱現像感光材料
US5641805A (en) 1995-06-06 1997-06-24 Alcon Laboratories, Inc. Topical ophthalmic formulations for treating allergic eye diseases
US6225327B1 (en) 1996-04-18 2001-05-01 Alcon Laboratories, Inc. Compounds which inhibit human conjunctival mast cell degranulation for treating ocular allergic-type complications
JP2894445B2 (ja) 1997-02-12 1999-05-24 日本たばこ産業株式会社 Ｃｅｔｐ活性阻害剤として有効な化合物
JP3940201B2 (ja) 1997-05-20 2007-07-04 大塚製薬株式会社 ３，３’−ジチオジベンゾヒドロキサム酸

Also Published As

Publication number Publication date
AU5567501A (en) 2001-12-03
MXPA02011481A (es) 2003-06-06
EP1282599A1 (en) 2003-02-12
ES2261402T3 (es) 2006-11-16
CN1616422A (zh) 2005-05-18
DE60120961D1 (de) 2006-08-03
PT1282599E (pt) 2006-08-31
BR0110943A (pt) 2004-01-06
AR028566A1 (es) 2003-05-14
CN1429209A (zh) 2003-07-09
US6506802B2 (en) 2003-01-14
US6500864B1 (en) 2002-12-31
EP1282599B1 (en) 2006-06-21
DK1282599T3 (da) 2006-07-31
WO2001090060A1 (en) 2001-11-29
ZA200208840B (en) 2003-12-02
CN1175807C (zh) 2004-11-17
US20020193633A1 (en) 2002-12-19
US6492552B2 (en) 2002-12-10
US20020193634A1 (en) 2002-12-19
CN1241912C (zh) 2006-02-15
US20020058709A1 (en) 2002-05-16
AU2001255675B2 (en) 2005-04-14
ATE330938T1 (de) 2006-07-15
DE60120961T2 (de) 2006-11-16
CA2407964A1 (en) 2001-11-29
HK1050185A1 (en) 2003-06-13
KR20030007589A (ko) 2003-01-23
PL365457A1 (en) 2005-01-10
JP2003534318A (ja) 2003-11-18

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