PT1189912E - Novas formas cristalinas de um antibiótico macrólido - Google Patents

Novas formas cristalinas de um antibiótico macrólido Download PDF

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Publication number
PT1189912E
PT1189912E PT00914336T PT00914336T PT1189912E PT 1189912 E PT1189912 E PT 1189912E PT 00914336 T PT00914336 T PT 00914336T PT 00914336 T PT00914336 T PT 00914336T PT 1189912 E PT1189912 E PT 1189912E
Authority
PT
Portugal
Prior art keywords
crystalline forms
novel crystalline
macrolide antibiotic
macrolide
antibiotic
Prior art date
Application number
PT00914336T
Other languages
English (en)
Portuguese (pt)
Inventor
Barry James Morton
Colman Brendan Ragan
Robert John Rafka
Douglas John Meldrum Allen
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of PT1189912E publication Critical patent/PT1189912E/pt

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Veterinary Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
PT00914336T 1999-05-18 2000-04-14 Novas formas cristalinas de um antibiótico macrólido PT1189912E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US13464499P 1999-05-18 1999-05-18

Publications (1)

Publication Number Publication Date
PT1189912E true PT1189912E (pt) 2008-05-16

Family

ID=22464300

Family Applications (1)

Application Number Title Priority Date Filing Date
PT00914336T PT1189912E (pt) 1999-05-18 2000-04-14 Novas formas cristalinas de um antibiótico macrólido

Country Status (43)

Country Link
US (1) US6583274B1 (enExample)
EP (1) EP1189912B1 (enExample)
JP (1) JP3897983B2 (enExample)
KR (1) KR100474229B1 (enExample)
CN (1) CN1203084C (enExample)
AP (1) AP2001002325A0 (enExample)
AR (1) AR020030A1 (enExample)
AT (1) ATE392427T1 (enExample)
AU (1) AU772283B2 (enExample)
BG (1) BG106150A (enExample)
BR (1) BR0011300A (enExample)
CA (1) CA2372206C (enExample)
CZ (1) CZ20014120A3 (enExample)
DE (1) DE60038610T2 (enExample)
DK (1) DK1189912T3 (enExample)
DZ (1) DZ3043A1 (enExample)
EA (1) EA003417B1 (enExample)
ES (1) ES2302689T3 (enExample)
GT (1) GT200000072A (enExample)
HK (1) HK1045521B (enExample)
HN (1) HN2000000056A (enExample)
HR (1) HRP20010849A2 (enExample)
HU (1) HUP0201341A3 (enExample)
IL (2) IL145946A0 (enExample)
IS (1) IS6127A (enExample)
MA (1) MA26735A1 (enExample)
MX (1) MXPA01011914A (enExample)
MY (1) MY133397A (enExample)
NO (1) NO320195B1 (enExample)
NZ (1) NZ514765A (enExample)
OA (1) OA11876A (enExample)
PA (1) PA8495001A1 (enExample)
PE (1) PE20010151A1 (enExample)
PL (1) PL353316A1 (enExample)
PT (1) PT1189912E (enExample)
SK (1) SK16472001A3 (enExample)
TN (1) TNSN00103A1 (enExample)
TW (1) TWI225066B (enExample)
UA (1) UA67842C2 (enExample)
UY (1) UY26144A1 (enExample)
WO (1) WO2000069874A1 (enExample)
YU (1) YU76601A (enExample)
ZA (1) ZA200109420B (enExample)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6465437B1 (en) * 1999-06-30 2002-10-15 Pfizer Inc. Diphosphate salt of a 4″-substituted-9-deoxo-9A-AZA-9A- homoerythromycin derivative and its pharmaceutical composition
AU779748C (en) * 2000-01-27 2005-12-08 Zoetis Services Llc Azalide antibiotic compositions
CN1297564C (zh) * 2001-04-27 2007-01-31 辉瑞产品公司 4″－取代－9－脱氧－9a－氮杂－9a－高红霉素A衍生物的制备方法
AU2003271408B2 (en) * 2002-12-31 2008-07-17 Alembic Limited A process for the purification of roxithromycin
US7384921B2 (en) * 2004-02-20 2008-06-10 Enanta Pharmaceuticals, Inc. Polymorphic forms of 6-11 bicyclic ketolide derivatives
AU2010209732B2 (en) * 2009-01-30 2012-12-20 Glaxo Group Limited Anti-inflammatory macrolide
EP2402355A1 (en) * 2010-07-01 2012-01-04 Novartis AG Crystalline anhydrous forms II and III of Tulathromycin
EP2736915A1 (en) 2011-07-27 2014-06-04 Farma GRS, d.o.o. New crystalline forms of tulathromycin
CN106008622A (zh) * 2016-08-02 2016-10-12 海门慧聚药业有限公司 泰拉霉素新晶型及其制备
CN109942652B (zh) * 2017-12-21 2022-04-26 洛阳惠中兽药有限公司 一种莱柯霉素晶型ⅰ及其制备方法和应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RO107257B1 (ro) * 1987-07-09 1993-10-30 Pfizer Procedeu de obtinere a unui dihidrat de azitromicina, cristalin
US5441939A (en) * 1994-03-04 1995-08-15 Pfizer Inc. 3"-desmethoxy derivatives of erythromycin and azithromycin
US5844105A (en) * 1996-07-29 1998-12-01 Abbott Laboratories Preparation of crystal form II of clarithromycin
HN1998000086A (es) * 1997-06-11 1999-03-08 Pfizer Prod Inc Derivados de 9 - desofo - 9 aza - 9a - homoeritromicina a - c - 4 sustituidos.

Also Published As

Publication number Publication date
ES2302689T3 (es) 2008-08-01
JP3897983B2 (ja) 2007-03-28
CZ20014120A3 (cs) 2003-01-15
HRP20010849A2 (en) 2003-04-30
AU772283B2 (en) 2004-04-22
US6583274B1 (en) 2003-06-24
KR100474229B1 (ko) 2005-03-08
AR020030A1 (es) 2002-03-27
ATE392427T1 (de) 2008-05-15
ZA200109420B (en) 2002-11-15
IL145946A0 (en) 2002-07-25
AP2001002325A0 (en) 2001-12-31
HUP0201341A2 (en) 2002-08-28
UY26144A1 (es) 2000-12-29
HUP0201341A3 (en) 2003-03-28
DE60038610T2 (de) 2009-06-25
DE60038610D1 (de) 2008-05-29
MA26735A1 (fr) 2004-12-20
SK16472001A3 (sk) 2003-02-04
PA8495001A1 (es) 2002-02-21
CA2372206C (en) 2006-01-10
MXPA01011914A (es) 2002-05-06
PL353316A1 (en) 2003-11-17
BG106150A (bg) 2002-05-31
MY133397A (en) 2007-11-30
DK1189912T3 (da) 2008-06-30
EP1189912B1 (en) 2008-04-16
KR20020007415A (ko) 2002-01-26
AU3572900A (en) 2000-12-05
NO320195B1 (no) 2005-11-14
EA200100984A1 (ru) 2002-06-27
HN2000000056A (es) 2001-02-02
CA2372206A1 (en) 2000-11-23
TNSN00103A1 (fr) 2005-11-10
CN1351607A (zh) 2002-05-29
BR0011300A (pt) 2002-02-26
EA003417B1 (ru) 2003-04-24
DZ3043A1 (fr) 2004-03-27
NO20015598L (no) 2002-01-08
NZ514765A (en) 2004-05-28
JP2002544283A (ja) 2002-12-24
GT200000072A (es) 2001-11-08
IS6127A (is) 2001-10-26
UA67842C2 (uk) 2004-07-15
NO20015598D0 (no) 2001-11-16
CN1203084C (zh) 2005-05-25
WO2000069874A1 (en) 2000-11-23
IL145946A (en) 2007-06-17
HK1045521B (zh) 2005-12-09
EP1189912A1 (en) 2002-03-27
HK1045521A1 (en) 2002-11-29
YU76601A (sh) 2004-09-03
OA11876A (en) 2006-03-27
TWI225066B (en) 2004-12-11
PE20010151A1 (es) 2001-02-08

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