HRP20010849A2 - Novel crystalline forms of a macrolide antibiotic - Google Patents

Novel crystalline forms of a macrolide antibiotic Download PDF

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Publication number
HRP20010849A2
HRP20010849A2 HR20010849A HRP20010849A HRP20010849A2 HR P20010849 A2 HRP20010849 A2 HR P20010849A2 HR 20010849 A HR20010849 A HR 20010849A HR P20010849 A HRP20010849 A HR P20010849A HR P20010849 A2 HRP20010849 A2 HR P20010849A2
Authority
HR
Croatia
Prior art keywords
crystalline form
form according
compound
formula
image
Prior art date
Application number
HR20010849A
Other languages
English (en)
Croatian (hr)
Inventor
Robert John Rafka
Douglas John Meldrum Allen
Colman Brendan Ragan
Barry James Morton
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of HRP20010849A2 publication Critical patent/HRP20010849A2/hr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
HR20010849A 1999-05-18 2000-04-14 Novel crystalline forms of a macrolide antibiotic HRP20010849A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US13464499P 1999-05-18 1999-05-18
PCT/IB2000/000463 WO2000069874A1 (en) 1999-05-18 2000-04-14 Novel crystalline forms of a macrolide antibiotic

Publications (1)

Publication Number Publication Date
HRP20010849A2 true HRP20010849A2 (en) 2003-04-30

Family

ID=22464300

Family Applications (1)

Application Number Title Priority Date Filing Date
HR20010849A HRP20010849A2 (en) 1999-05-18 2000-04-14 Novel crystalline forms of a macrolide antibiotic

Country Status (43)

Country Link
US (1) US6583274B1 (enExample)
EP (1) EP1189912B1 (enExample)
JP (1) JP3897983B2 (enExample)
KR (1) KR100474229B1 (enExample)
CN (1) CN1203084C (enExample)
AP (1) AP2001002325A0 (enExample)
AR (1) AR020030A1 (enExample)
AT (1) ATE392427T1 (enExample)
AU (1) AU772283B2 (enExample)
BG (1) BG106150A (enExample)
BR (1) BR0011300A (enExample)
CA (1) CA2372206C (enExample)
CZ (1) CZ20014120A3 (enExample)
DE (1) DE60038610T2 (enExample)
DK (1) DK1189912T3 (enExample)
DZ (1) DZ3043A1 (enExample)
EA (1) EA003417B1 (enExample)
ES (1) ES2302689T3 (enExample)
GT (1) GT200000072A (enExample)
HK (1) HK1045521B (enExample)
HN (1) HN2000000056A (enExample)
HR (1) HRP20010849A2 (enExample)
HU (1) HUP0201341A3 (enExample)
IL (2) IL145946A0 (enExample)
IS (1) IS6127A (enExample)
MA (1) MA26735A1 (enExample)
MX (1) MXPA01011914A (enExample)
MY (1) MY133397A (enExample)
NO (1) NO320195B1 (enExample)
NZ (1) NZ514765A (enExample)
OA (1) OA11876A (enExample)
PA (1) PA8495001A1 (enExample)
PE (1) PE20010151A1 (enExample)
PL (1) PL353316A1 (enExample)
PT (1) PT1189912E (enExample)
SK (1) SK16472001A3 (enExample)
TN (1) TNSN00103A1 (enExample)
TW (1) TWI225066B (enExample)
UA (1) UA67842C2 (enExample)
UY (1) UY26144A1 (enExample)
WO (1) WO2000069874A1 (enExample)
YU (1) YU76601A (enExample)
ZA (1) ZA200109420B (enExample)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6465437B1 (en) * 1999-06-30 2002-10-15 Pfizer Inc. Diphosphate salt of a 4″-substituted-9-deoxo-9A-AZA-9A- homoerythromycin derivative and its pharmaceutical composition
ATE243703T1 (de) * 2000-01-27 2003-07-15 Pfizer Prod Inc Antibiotische azalid-zusammensetzungen
CA2445306C (en) * 2001-04-27 2008-02-12 Pfizer Products Inc. Process for preparing 4"-substituted-9-deoxo-9a-aza-9a-homoerythromycin a derivatives
EP1435359A1 (en) * 2002-12-31 2004-07-07 Alembic Limited A process for the purification of roxithromycin
US7384921B2 (en) * 2004-02-20 2008-06-10 Enanta Pharmaceuticals, Inc. Polymorphic forms of 6-11 bicyclic ketolide derivatives
JP5437394B2 (ja) * 2009-01-30 2014-03-12 グラクソ グループ リミテッド 抗炎症性マクロライド
EP2402355A1 (en) * 2010-07-01 2012-01-04 Novartis AG Crystalline anhydrous forms II and III of Tulathromycin
EP2736915A1 (en) 2011-07-27 2014-06-04 Farma GRS, d.o.o. New crystalline forms of tulathromycin
CN106008622A (zh) * 2016-08-02 2016-10-12 海门慧聚药业有限公司 泰拉霉素新晶型及其制备
CN109942652B (zh) * 2017-12-21 2022-04-26 洛阳惠中兽药有限公司 一种莱柯霉素晶型ⅰ及其制备方法和应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX12213A (es) * 1987-07-09 1993-05-01 Pfizer Metodo de preparacion de dihidrato de azitromicina cristalino
US5441939A (en) * 1994-03-04 1995-08-15 Pfizer Inc. 3"-desmethoxy derivatives of erythromycin and azithromycin
US5844105A (en) * 1996-07-29 1998-12-01 Abbott Laboratories Preparation of crystal form II of clarithromycin
HN1998000086A (es) * 1997-06-11 1999-03-08 Pfizer Prod Inc Derivados de 9 - desofo - 9 aza - 9a - homoeritromicina a - c - 4 sustituidos.

Also Published As

Publication number Publication date
IL145946A (en) 2007-06-17
PL353316A1 (en) 2003-11-17
UA67842C2 (uk) 2004-07-15
CA2372206C (en) 2006-01-10
NZ514765A (en) 2004-05-28
CN1351607A (zh) 2002-05-29
HN2000000056A (es) 2001-02-02
TWI225066B (en) 2004-12-11
US6583274B1 (en) 2003-06-24
EA003417B1 (ru) 2003-04-24
ZA200109420B (en) 2002-11-15
KR20020007415A (ko) 2002-01-26
AU772283B2 (en) 2004-04-22
ATE392427T1 (de) 2008-05-15
PA8495001A1 (es) 2002-02-21
DE60038610T2 (de) 2009-06-25
PE20010151A1 (es) 2001-02-08
JP3897983B2 (ja) 2007-03-28
CN1203084C (zh) 2005-05-25
JP2002544283A (ja) 2002-12-24
HK1045521B (zh) 2005-12-09
GT200000072A (es) 2001-11-08
AR020030A1 (es) 2002-03-27
EP1189912A1 (en) 2002-03-27
DE60038610D1 (de) 2008-05-29
YU76601A (sh) 2004-09-03
CZ20014120A3 (cs) 2003-01-15
OA11876A (en) 2006-03-27
HK1045521A1 (en) 2002-11-29
AU3572900A (en) 2000-12-05
WO2000069874A1 (en) 2000-11-23
IL145946A0 (en) 2002-07-25
CA2372206A1 (en) 2000-11-23
BG106150A (bg) 2002-05-31
SK16472001A3 (sk) 2003-02-04
BR0011300A (pt) 2002-02-26
UY26144A1 (es) 2000-12-29
NO20015598L (no) 2002-01-08
HUP0201341A2 (en) 2002-08-28
ES2302689T3 (es) 2008-08-01
TNSN00103A1 (fr) 2005-11-10
HUP0201341A3 (en) 2003-03-28
NO320195B1 (no) 2005-11-14
EP1189912B1 (en) 2008-04-16
MXPA01011914A (es) 2002-05-06
AP2001002325A0 (en) 2001-12-31
MA26735A1 (fr) 2004-12-20
DK1189912T3 (da) 2008-06-30
MY133397A (en) 2007-11-30
IS6127A (is) 2001-10-26
PT1189912E (pt) 2008-05-16
EA200100984A1 (ru) 2002-06-27
NO20015598D0 (no) 2001-11-16
DZ3043A1 (fr) 2004-03-27
KR100474229B1 (ko) 2005-03-08

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