PT1188841E - Sonda para construir um polímero sonda, método de construção do polímero sonda e a sua utilização - Google Patents

Sonda para construir um polímero sonda, método de construção do polímero sonda e a sua utilização Download PDF

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Publication number
PT1188841E
PT1188841E PT01917537T PT01917537T PT1188841E PT 1188841 E PT1188841 E PT 1188841E PT 01917537 T PT01917537 T PT 01917537T PT 01917537 T PT01917537 T PT 01917537T PT 1188841 E PT1188841 E PT 1188841E
Authority
PT
Portugal
Prior art keywords
probe
polymer
target gene
constructing
complementary
Prior art date
Application number
PT01917537T
Other languages
English (en)
Inventor
Mitsugu Usui
Chikako Hakii
Mari Mitsuka
Original Assignee
Eisai R&D Man Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eisai R&D Man Co Ltd filed Critical Eisai R&D Man Co Ltd
Publication of PT1188841E publication Critical patent/PT1188841E/pt

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C12Q1/682—Signal amplification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6811—Selection methods for production or design of target specific oligonucleotides or binding molecules
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2527/00—Reactions demanding special reaction conditions
    • C12Q2527/101—Temperature

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Plant Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Immunology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analyzing Materials By The Use Of Ultrasonic Waves (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Polymerisation Methods In General (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
PT01917537T 2000-03-31 2001-03-28 Sonda para construir um polímero sonda, método de construção do polímero sonda e a sua utilização PT1188841E (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2000098797 2000-03-31
JP2000309959 2000-10-10

Publications (1)

Publication Number Publication Date
PT1188841E true PT1188841E (pt) 2009-03-24

Family

ID=26589206

Family Applications (1)

Application Number Title Priority Date Filing Date
PT01917537T PT1188841E (pt) 2000-03-31 2001-03-28 Sonda para construir um polímero sonda, método de construção do polímero sonda e a sua utilização

Country Status (13)

Country Link
US (1) US7060814B2 (pt)
EP (1) EP1188841B1 (pt)
JP (1) JP3310662B2 (pt)
KR (1) KR100446358B1 (pt)
CN (1) CN1364199B (pt)
AT (1) ATE418620T1 (pt)
AU (1) AU747848B2 (pt)
CA (1) CA2387755C (pt)
DE (1) DE60137104D1 (pt)
DK (1) DK1188841T3 (pt)
ES (1) ES2317893T3 (pt)
PT (1) PT1188841E (pt)
WO (1) WO2001075157A1 (pt)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1229131A1 (en) * 2000-08-30 2002-08-07 Sanko Junyaku Co., Ltd. Method of detecting gene
EP1431386A1 (en) * 2001-09-28 2004-06-23 Sanko Junyaku Co., Ltd. Method of amplifying dna chip signals
JPWO2003040367A1 (ja) 2001-11-08 2005-03-03 三光純薬株式会社 遺伝子増幅反応で合成されたオリゴヌクレオチドによる自己集合体の形成方法、自己集合体及び遺伝子の検出方法
KR101050510B1 (ko) * 2003-02-14 2011-07-20 에자이 알앤드디 매니지먼트 가부시키가이샤 발현 유전자 검출을 위한 신호 증폭 방법
EP1595953B1 (en) * 2003-02-21 2012-04-04 Eisai R&D Management Co., Ltd. Signal amplification method for detecting mutant gene
JP2005304489A (ja) * 2004-03-24 2005-11-04 Sysmex Corp 標的物質検出用プローブセット及び標的物質検出方法。
CA2564838A1 (en) * 2004-04-28 2005-11-10 Eisai R&D Management Co., Ltd. Hybridization method
WO2006028162A1 (ja) * 2004-09-08 2006-03-16 Eisai R & D Management Co., Ltd. シグナルプローブポリマーの形成方法
US7862998B2 (en) 2005-02-28 2011-01-04 Eisai R&D Management Co., Ltd. Assist probe and method of using the same
JP4616881B2 (ja) 2005-02-28 2011-01-19 エーザイ・アール・アンド・ディー・マネジメント株式会社 アシストプローブ及びその利用方法
JP3941828B2 (ja) * 2005-09-15 2007-07-04 トヨタ自動車株式会社 内燃機関の空燃比制御装置
JP4847961B2 (ja) 2005-09-27 2011-12-28 エーザイ・アール・アンド・ディー・マネジメント株式会社 微小粒子に自己集合体を形成させる方法及び標的分析物の検出方法
US7927804B2 (en) 2006-03-15 2011-04-19 Eisai & Managment Co., Ltd. Method of forming signal probe-polymer
US20100256007A1 (en) * 2007-10-24 2010-10-07 Mitsugu Usui Nucleic acid probe, and method of forming probe-polymer
US20110171639A1 (en) 2007-10-31 2011-07-14 Eisai R&D Management Co., Ltd. Polymer for detection of target substance, and method for detection of target substance
JP2012070635A (ja) * 2009-01-29 2012-04-12 Eisai R & D Management Co Ltd 核酸の検出方法
WO2012144560A1 (ja) * 2011-04-19 2012-10-26 国立大学法人京都大学 自己ゲル化核酸
CN102703584B (zh) * 2012-04-20 2013-08-21 中国人民解放军第四军医大学 自组装聚合分支dna探针的制备方法
EP2851425A1 (en) 2012-05-15 2015-03-25 Eisai R&D Management Co., Ltd. Rna detection method and detection kit
US20150105298A1 (en) * 2013-10-10 2015-04-16 The Research Foundation For The State University Of New York Multi-oligomer in situ hybridization probes
TW201936929A (zh) * 2018-02-26 2019-09-16 美商Ｃｙ分子診斷公司 以親和力為導向的富集稀少分子的組成物及方法

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US5288609A (en) 1984-04-27 1994-02-22 Enzo Diagnostics, Inc. Capture sandwich hybridization method and composition
CA1260372A (en) * 1984-04-27 1989-09-26 Elazar Rabbani Hybridization method for the detection of genetic materials
US4882269A (en) * 1985-12-13 1989-11-21 Princeton University Amplified hybridization assay
US4851331A (en) * 1986-05-16 1989-07-25 Allied Corporation Method and kit for polynucleotide assay including primer-dependant DNA polymerase
US5175270A (en) * 1986-09-10 1992-12-29 Polyprobe, Inc. Reagents for detecting and assaying nucleic acid sequences
AU8103687A (en) 1986-10-14 1988-05-06 Beckman Instruments, Inc. Improved nucleic acid hybridization technique and kit therefor
AU2735988A (en) 1987-12-21 1989-07-13 Amoco Corporation Target and background capture methods with amplification for affinity assays
US4895325A (en) 1988-11-10 1990-01-23 Safetran Systems Corporation Railroad gate arm lamp circuit
CA2035010C (en) * 1990-01-26 1996-12-10 Keith C. Backman Method of amplifying target nucleic acids applicable to both polymerase and ligase chain reactions
CA2039517C (en) * 1990-04-03 2006-11-07 David Segev Dna probe signal amplification
US5232831A (en) * 1991-06-28 1993-08-03 Gen-Probe Incorporated Nucleic acid probes to streptococcus pyogenes
US5216143A (en) * 1991-06-28 1993-06-01 Gen-Probe Products Company Nucleic acid probes to mycobacterium gordonae
FR2710075B1 (fr) * 1993-09-15 1995-10-27 Bio Merieux Réactif et procédé pour la détection d'une séquence nucléotidique avec amplification de signal.
US5561043A (en) * 1994-01-31 1996-10-01 Trustees Of Boston University Self-assembling multimeric nucleic acid constructs
US5853993A (en) * 1996-10-21 1998-12-29 Hewlett-Packard Company Signal enhancement method and kit
JP3947597B2 (ja) * 1997-06-06 2007-07-25 栄研化学株式会社 核酸配列の増幅方法
JP4221145B2 (ja) * 1997-07-29 2009-02-12 ポリプローブ，インコーポレイテッド 最大の自己アセンブリを行う樹枝状核酸
JP3267576B2 (ja) * 1998-11-09 2002-03-18 三光純薬株式会社 プローブ高分子の形成方法
US6277607B1 (en) * 1999-05-24 2001-08-21 Sanjay Tyagi High specificity primers, amplification methods and kits
DE60123626T2 (de) * 2000-10-11 2007-01-18 Sanko Junyaku Co., Ltd. Verfahren zur konstruktion von selbstassemlbierenden sonden und verfahren zu ihrer detektion

Also Published As

Publication number Publication date
US20030008294A1 (en) 2003-01-09
EP1188841B1 (en) 2008-12-24
CA2387755A1 (en) 2001-10-11
EP1188841A4 (en) 2005-01-05
AU4458301A (en) 2001-10-15
CA2387755C (en) 2007-07-03
ATE418620T1 (de) 2009-01-15
KR100446358B1 (ko) 2004-09-01
CN1364199B (zh) 2012-05-09
DK1188841T3 (da) 2009-04-20
CN1364199A (zh) 2002-08-14
KR20020033599A (ko) 2002-05-07
AU747848B2 (en) 2002-05-23
ES2317893T3 (es) 2009-05-01
DE60137104D1 (de) 2009-02-05
US7060814B2 (en) 2006-06-13
EP1188841A1 (en) 2002-03-20
JP3310662B2 (ja) 2002-08-05
WO2001075157A1 (fr) 2001-10-11

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