PT1037658E - Complexo ifnar2/ifn - Google Patents

Complexo ifnar2/ifn

Info

Publication number
PT1037658E
PT1037658E PT98964071T PT98964071T PT1037658E PT 1037658 E PT1037658 E PT 1037658E PT 98964071 T PT98964071 T PT 98964071T PT 98964071 T PT98964071 T PT 98964071T PT 1037658 E PT1037658 E PT 1037658E
Authority
PT
Portugal
Prior art keywords
ifnar2
ifn complex
ifn
complex
Prior art date
Application number
PT98964071T
Other languages
English (en)
Inventor
Mark Tepper
Mark Cunningham
David Sherris
Nabil El Tayar
Sean Mckenna
Original Assignee
Applied Research Systems
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Applied Research Systems filed Critical Applied Research Systems
Publication of PT1037658E publication Critical patent/PT1037658E/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/21—Interferons [IFN]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/555—Interferons [IFN]
    • C07K14/56—IFN-alpha
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/555—Interferons [IFN]
    • C07K14/565—IFN-beta
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Cell Biology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
PT98964071T 1997-12-19 1998-12-18 Complexo ifnar2/ifn PT1037658E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US6829597P 1997-12-19 1997-12-19

Publications (1)

Publication Number Publication Date
PT1037658E true PT1037658E (pt) 2002-10-31

Family

ID=22081665

Family Applications (1)

Application Number Title Priority Date Filing Date
PT98964071T PT1037658E (pt) 1997-12-19 1998-12-18 Complexo ifnar2/ifn

Country Status (28)

Country Link
US (1) US6372207B1 (pt)
EP (1) EP1037658B1 (pt)
JP (1) JP4601163B2 (pt)
KR (1) KR100593981B1 (pt)
CN (1) CN1241638C (pt)
AR (1) AR020315A1 (pt)
AT (1) ATE218362T1 (pt)
AU (1) AU755078B2 (pt)
BG (1) BG64920B1 (pt)
BR (1) BR9813753A (pt)
CA (1) CA2311648C (pt)
DE (1) DE69805844T2 (pt)
DK (1) DK1037658T3 (pt)
EA (1) EA003635B1 (pt)
EE (1) EE200000355A (pt)
ES (1) ES2174530T3 (pt)
HK (1) HK1032914A1 (pt)
HU (1) HUP0100456A3 (pt)
IL (2) IL136855A0 (pt)
NO (1) NO20002691L (pt)
NZ (1) NZ504771A (pt)
PL (1) PL197568B1 (pt)
PT (1) PT1037658E (pt)
SK (1) SK9222000A3 (pt)
TR (1) TR200001961T2 (pt)
UA (1) UA74132C2 (pt)
WO (1) WO1999032141A1 (pt)
ZA (1) ZA9811634B (pt)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL122818A0 (en) * 1997-07-10 1998-08-16 Yeda Res & Dev Chimeric interleukin-6 soluble receptor/ligand protein analogs thereof and uses thereof
AUPP670698A0 (en) * 1998-10-23 1998-11-19 Monash University A method of regulation
US7138379B2 (en) 2000-07-26 2006-11-21 Schering Aktiengesellschaft Use of the interferon receptor 2c polypeptide chain to enhance the anti-growth effects of type I interferons
IL147414A0 (en) 2001-12-31 2002-08-14 Yeda Res & Dev Ifnar2 mutants, their production and use
US20040175359A1 (en) * 2002-11-12 2004-09-09 Desjarlais John Rudolph Novel proteins with antiviral, antineoplastic, and/or immunomodulatory activity
JP4850514B2 (ja) * 2003-08-25 2012-01-11 東レ株式会社 インターフェロンβ複合体
CN100400664C (zh) * 2005-09-06 2008-07-09 中国人民解放军第四军医大学 肿瘤血管导向肽与人干扰素α-2b的融合蛋白的制备方法
WO2008130382A2 (en) 2006-10-31 2008-10-30 East Carolina University Fusion proteins comprising an anti -inflammatory cytokine and an antigen for treatment of immune disorders
GB0715383D0 (en) * 2007-08-08 2007-09-19 Asterion Ltd Interferon
GB0815216D0 (en) * 2008-08-21 2008-09-24 Asterion Ltd Interleukin
EP2413958A4 (en) 2009-03-31 2014-04-02 Univ East Carolina CYTOKINES AND NEUROANTIGENES FOR THE TREATMENT OF IMMUNE DISEASES
KR101293363B1 (ko) * 2011-02-28 2013-08-05 성균관대학교산학협력단 인터페론 수용체 유전자를 포함하는 조류독감 예방용 조성물
MX366124B (es) * 2013-03-15 2019-06-27 Janssen Biotech Inc Anticuerpos antagonistas del interferón alfa y omega.
LT6164B (lt) 2013-10-15 2015-06-25 Uab Biotechnologinės Farmacijos Centras "Biotechpharma" Sulieti interferono-alfa 5 baltymai su kitu citokinu ir jų gamybos būdas
CN111050803A (zh) * 2017-06-20 2020-04-21 德克萨斯大学系统董事会 用于治疗癌症的干扰素前药
US10947295B2 (en) 2017-08-22 2021-03-16 Sanabio, Llc Heterodimers of soluble interferon receptors and uses thereof
CN112646783B (zh) * 2020-12-30 2023-12-01 广州医科大学附属市八医院 表达基因、经基因修饰的受精卵的构建方法和小鼠模型的构建方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL106591A (en) 1992-09-03 2008-03-20 Yeda Res & Dev Interferon alpha/beta binding protein, its preparation and pharmaceutical compositions containing it
US5821078A (en) * 1992-09-03 1998-10-13 Yeda Research And Development Co. Ltd. Nucleic acid encoding interferon-α/β binding protein
IL107378A (en) * 1993-10-24 2005-05-17 Yeda Res & Dev SOLUBLE INTERFERON alpha-RECEPTOR, ITS PREPARATION AND USE

Also Published As

Publication number Publication date
EP1037658B1 (en) 2002-06-05
PL341423A1 (en) 2001-04-09
CN1282255A (zh) 2001-01-31
AU755078B2 (en) 2002-12-05
EP1037658A1 (en) 2000-09-27
NO20002691L (no) 2000-08-18
TR200001961T2 (tr) 2000-11-21
DK1037658T3 (da) 2002-09-30
NO20002691D0 (no) 2000-05-25
PL197568B1 (pl) 2008-04-30
JP4601163B2 (ja) 2010-12-22
EA200000685A1 (ru) 2000-12-25
BR9813753A (pt) 2000-10-10
AU1926999A (en) 1999-07-12
HK1032914A1 (en) 2001-08-10
JP2001526242A (ja) 2001-12-18
NZ504771A (en) 2002-09-27
DE69805844T2 (de) 2002-10-24
EA003635B1 (ru) 2003-08-28
ATE218362T1 (de) 2002-06-15
IL136855A0 (en) 2001-06-14
UA74132C2 (uk) 2005-11-15
AR020315A1 (es) 2002-05-08
WO1999032141A1 (en) 1999-07-01
US6372207B1 (en) 2002-04-16
KR20010032836A (ko) 2001-04-25
DE69805844D1 (de) 2002-07-11
HUP0100456A1 (hu) 2001-06-28
BG104539A (en) 2001-04-30
ZA9811634B (en) 1999-06-22
IL136855A (en) 2007-07-24
ES2174530T3 (es) 2002-11-01
CA2311648C (en) 2010-11-16
BG64920B1 (bg) 2006-09-29
CN1241638C (zh) 2006-02-15
KR100593981B1 (ko) 2006-06-30
SK9222000A3 (en) 2001-01-18
HUP0100456A3 (en) 2003-09-29
CA2311648A1 (en) 1999-07-01
EE200000355A (et) 2001-10-15

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