EE200000355A - IFN/IFNAR kompleks ja vastav molekul ning nende kasutamine, DNA, peremeesrakk, liitvalgu valmistamismeetod, I tüüpi IFN säilimisaja pikendamise meetod, farmatseutiline kompositsioon ja IFNAR kasutamine - Google Patents
IFN/IFNAR kompleks ja vastav molekul ning nende kasutamine, DNA, peremeesrakk, liitvalgu valmistamismeetod, I tüüpi IFN säilimisaja pikendamise meetod, farmatseutiline kompositsioon ja IFNAR kasutamineInfo
- Publication number
- EE200000355A EE200000355A EEP200000355A EEP200000355A EE200000355A EE 200000355 A EE200000355 A EE 200000355A EE P200000355 A EEP200000355 A EE P200000355A EE P200000355 A EEP200000355 A EE P200000355A EE 200000355 A EE200000355 A EE 200000355A
- Authority
- EE
- Estonia
- Prior art keywords
- ifnar
- ifn
- dna
- pharmaceutical composition
- host cell
- Prior art date
Links
- 101000852870 Homo sapiens Interferon alpha/beta receptor 1 Proteins 0.000 title 2
- 102100036714 Interferon alpha/beta receptor 1 Human genes 0.000 title 2
- 108020001507 fusion proteins Proteins 0.000 title 1
- 102000037865 fusion proteins Human genes 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 230000014616 translation Effects 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/21—Interferons [IFN]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/555—Interferons [IFN]
- C07K14/56—IFN-alpha
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/555—Interferons [IFN]
- C07K14/565—IFN-beta
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Toxicology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Cell Biology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Virology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US6829597P | 1997-12-19 | 1997-12-19 | |
PCT/US1998/026926 WO1999032141A1 (en) | 1997-12-19 | 1998-12-18 | Ifnar2/ifn complex |
Publications (1)
Publication Number | Publication Date |
---|---|
EE200000355A true EE200000355A (et) | 2001-10-15 |
Family
ID=22081665
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EEP200000355A EE200000355A (et) | 1997-12-19 | 1998-12-18 | IFN/IFNAR kompleks ja vastav molekul ning nende kasutamine, DNA, peremeesrakk, liitvalgu valmistamismeetod, I tüüpi IFN säilimisaja pikendamise meetod, farmatseutiline kompositsioon ja IFNAR kasutamine |
Country Status (28)
Country | Link |
---|---|
US (1) | US6372207B1 (xx) |
EP (1) | EP1037658B1 (xx) |
JP (1) | JP4601163B2 (xx) |
KR (1) | KR100593981B1 (xx) |
CN (1) | CN1241638C (xx) |
AR (1) | AR020315A1 (xx) |
AT (1) | ATE218362T1 (xx) |
AU (1) | AU755078B2 (xx) |
BG (1) | BG64920B1 (xx) |
BR (1) | BR9813753A (xx) |
CA (1) | CA2311648C (xx) |
DE (1) | DE69805844T2 (xx) |
DK (1) | DK1037658T3 (xx) |
EA (1) | EA003635B1 (xx) |
EE (1) | EE200000355A (xx) |
ES (1) | ES2174530T3 (xx) |
HK (1) | HK1032914A1 (xx) |
HU (1) | HUP0100456A3 (xx) |
IL (2) | IL136855A0 (xx) |
NO (1) | NO20002691L (xx) |
NZ (1) | NZ504771A (xx) |
PL (1) | PL197568B1 (xx) |
PT (1) | PT1037658E (xx) |
SK (1) | SK9222000A3 (xx) |
TR (1) | TR200001961T2 (xx) |
UA (1) | UA74132C2 (xx) |
WO (1) | WO1999032141A1 (xx) |
ZA (1) | ZA9811634B (xx) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL122818A0 (en) * | 1997-07-10 | 1998-08-16 | Yeda Res & Dev | Chimeric interleukin-6 soluble receptor/ligand protein analogs thereof and uses thereof |
AUPP670698A0 (en) * | 1998-10-23 | 1998-11-19 | Monash University | A method of regulation |
US7138379B2 (en) * | 2000-07-26 | 2006-11-21 | Schering Aktiengesellschaft | Use of the interferon receptor 2c polypeptide chain to enhance the anti-growth effects of type I interferons |
IL147414A0 (en) * | 2001-12-31 | 2002-08-14 | Yeda Res & Dev | Ifnar2 mutants, their production and use |
US20040175359A1 (en) * | 2002-11-12 | 2004-09-09 | Desjarlais John Rudolph | Novel proteins with antiviral, antineoplastic, and/or immunomodulatory activity |
US7691975B2 (en) * | 2003-08-25 | 2010-04-06 | Toray Industries, Inc. | Interferon-β complex |
CN100400664C (zh) * | 2005-09-06 | 2008-07-09 | 中国人民解放军第四军医大学 | 肿瘤血管导向肽与人干扰素α-2b的融合蛋白的制备方法 |
US8920808B2 (en) | 2006-10-31 | 2014-12-30 | East Carolina University | Cytokine-based fusion proteins for treatment of multiple sclerosis |
GB0715383D0 (en) * | 2007-08-08 | 2007-09-19 | Asterion Ltd | Interferon |
GB0815216D0 (en) * | 2008-08-21 | 2008-09-24 | Asterion Ltd | Interleukin |
AU2010234743A1 (en) | 2009-03-31 | 2011-10-20 | East Carolina University | Cytokines and neuroantigens for treatment of immune disorders |
KR101293363B1 (ko) * | 2011-02-28 | 2013-08-05 | 성균관대학교산학협력단 | 인터페론 수용체 유전자를 포함하는 조류독감 예방용 조성물 |
JP6466904B2 (ja) * | 2013-03-15 | 2019-02-06 | ヤンセン バイオテツク,インコーポレーテツド | インターフェロンアルファ及びオメガ抗体アンタゴニスト |
LT6164B (lt) | 2013-10-15 | 2015-06-25 | Uab Biotechnologinės Farmacijos Centras "Biotechpharma" | Sulieti interferono-alfa 5 baltymai su kitu citokinu ir jų gamybos būdas |
CN109790526A (zh) | 2016-07-01 | 2019-05-21 | 分解治疗有限责任公司 | 优化的二核酸酶融合体和方法 |
CN111050803A (zh) * | 2017-06-20 | 2020-04-21 | 德克萨斯大学系统董事会 | 用于治疗癌症的干扰素前药 |
KR20200039778A (ko) | 2017-08-22 | 2020-04-16 | 사나바이오, 엘엘씨 | 가용성 인터페론 수용체 및 그의 용도 |
CN112646783B (zh) * | 2020-12-30 | 2023-12-01 | 广州医科大学附属市八医院 | 表达基因、经基因修饰的受精卵的构建方法和小鼠模型的构建方法 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL106591A (en) | 1992-09-03 | 2008-03-20 | Yeda Res & Dev | Interferon alpha/beta binding protein, its preparation and pharmaceutical compositions containing it |
US5821078A (en) | 1992-09-03 | 1998-10-13 | Yeda Research And Development Co. Ltd. | Nucleic acid encoding interferon-α/β binding protein |
IL107378A (en) * | 1993-10-24 | 2005-05-17 | Yeda Res & Dev | SOLUBLE INTERFERON alpha-RECEPTOR, ITS PREPARATION AND USE |
-
1998
- 1998-12-18 PL PL341423A patent/PL197568B1/pl not_active IP Right Cessation
- 1998-12-18 JP JP2000525131A patent/JP4601163B2/ja not_active Expired - Fee Related
- 1998-12-18 EE EEP200000355A patent/EE200000355A/xx unknown
- 1998-12-18 AT AT98964071T patent/ATE218362T1/de not_active IP Right Cessation
- 1998-12-18 EP EP98964071A patent/EP1037658B1/en not_active Expired - Lifetime
- 1998-12-18 SK SK922-2000A patent/SK9222000A3/sk unknown
- 1998-12-18 ES ES98964071T patent/ES2174530T3/es not_active Expired - Lifetime
- 1998-12-18 EA EA200000685A patent/EA003635B1/ru not_active IP Right Cessation
- 1998-12-18 PT PT98964071T patent/PT1037658E/pt unknown
- 1998-12-18 DE DE69805844T patent/DE69805844T2/de not_active Expired - Lifetime
- 1998-12-18 DK DK98964071T patent/DK1037658T3/da active
- 1998-12-18 ZA ZA9811634A patent/ZA9811634B/xx unknown
- 1998-12-18 WO PCT/US1998/026926 patent/WO1999032141A1/en active IP Right Grant
- 1998-12-18 IL IL13685598A patent/IL136855A0/xx active IP Right Grant
- 1998-12-18 BR BR9813753-0A patent/BR9813753A/pt not_active Application Discontinuation
- 1998-12-18 AU AU19269/99A patent/AU755078B2/en not_active Ceased
- 1998-12-18 KR KR1020007006160A patent/KR100593981B1/ko not_active IP Right Cessation
- 1998-12-18 CA CA2311648A patent/CA2311648C/en not_active Expired - Fee Related
- 1998-12-18 TR TR2000/01961T patent/TR200001961T2/xx unknown
- 1998-12-18 CN CNB988123924A patent/CN1241638C/zh not_active Expired - Fee Related
- 1998-12-18 UA UA2000074350A patent/UA74132C2/uk unknown
- 1998-12-18 HU HU0100456A patent/HUP0100456A3/hu unknown
- 1998-12-18 US US09/215,212 patent/US6372207B1/en not_active Expired - Lifetime
- 1998-12-18 AR ARP980106515A patent/AR020315A1/es active IP Right Grant
- 1998-12-18 NZ NZ504771A patent/NZ504771A/xx unknown
-
2000
- 2000-05-25 NO NO20002691A patent/NO20002691L/no not_active Application Discontinuation
- 2000-06-15 BG BG104539A patent/BG64920B1/bg unknown
- 2000-06-18 IL IL136855A patent/IL136855A/en not_active IP Right Cessation
-
2001
- 2001-05-23 HK HK01103574A patent/HK1032914A1/xx not_active IP Right Cessation
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
EE200000355A (et) | IFN/IFNAR kompleks ja vastav molekul ning nende kasutamine, DNA, peremeesrakk, liitvalgu valmistamismeetod, I tüüpi IFN säilimisaja pikendamise meetod, farmatseutiline kompositsioon ja IFNAR kasutamine | |
EE200000152A (et) | Aminoterminaalselt kärbitud MCP-2 vormid, DNA molekulid, ekspressioonivektor, peremeesrakk, rekombinantne meetod proteiini valmistamiseks, proteiini kasutamine ning farmatseutiline kompositsioon | |
EP2277889A3 (en) | Fusion proteins of albumin and interferon beta | |
DE69732871D1 (de) | Basisches Protein Zusammensetzung, basisches Peptid Zusammensetzung und deren Verwendung | |
BR9602166A (pt) | Proteina de obesidade vetor de expressão proteina de fusão sequência de DNA organismo hospedeiro método de produzir proteina sequência OB de gene composição proteina OB humana uso e método de tratamento | |
DE59812907D1 (de) | Substituierte Isochinolin-3-Carbonsäureamide, ihre Herstellung und ihre Verwendung als Arzneimittel | |
PL324328A1 (en) | Novel nucleic acid construct, method of obtaining same, application thereof, method of manufacturing a pharmaceutic agent, method of producing cells, method of producing protein and pharmaceutic agent as such | |
BR9401321A (pt) | Muteína, sequência de DNA, vetor, célula, sequência de RNA composto, processo para sua preparação, composição farmacêutica e uso. | |
NO20010277D0 (no) | Benzocykloheptener, fremgangsmåte for fremstilling derav, farmasöytiske preparater inneholdende disse, og deres anvendelse for fremstilling av medikamenter | |
FR2723951B1 (fr) | Peptide, agent antibacterien contenant ce peptide, gene de ce peptide, adn recombine contenant ce gene et procede de preparation de ce peptide. | |
NO984352D0 (no) | Trisykliske forbindelser med aktivitet spesifikt for integriner, i sµrdeleshet <alfa>v<beta>3 integriner, metode for fremstilling av disse, mellomprodukter derfor, anvendelse for angitte forbindelser som legemidler, og farmas°ytiske preparater i | |
IT1291366B1 (it) | Composizione farmaceutica antivirale comprendente acido glicirrizico ed almeno una proteina dotata di attivita' antivirale | |
DK1117661T3 (da) | Propanolaminderivater substitueret med heterocycliske grupper, fremgangsmåde til deres fremstilling, farmaceutiske præparater indeholdende disse forbindelser og deres anvendelse | |
DE69731646D1 (de) | Verabreichung von nukleinsäurepartikeln | |
DE60037978D1 (de) | Interferon ähnliche moleküle, und deren verwendungen | |
AU7758598A (en) | Stable pharmaceutical administration forms of peptides, proteins and nucleic acids | |
CA2032167A1 (en) | Dna coding for protein binds to enhancer of.alpha.-fetoprotein gene | |
BR9812138A (pt) | Métodos e composições para terapias empregando genes codificando proteìnas segregadas tal como interferon-beta | |
AU6041298A (en) | Human apoptosis-associated protein; encoding dna is similar to p53 response mouse gene ei124 | |
BR9606521A (pt) | Polinucleotídeo purificado e isolado molécula de dna construção de expressão de dna célula hospedeira método para produzir um polipeptídeo humano polipeptídeo purificado e isolado anticorpo e linhagem celular de hibridoma | |
DE60009858D1 (de) | Hydrolysate aus Proteinen von Schwämmen und Verfahren zur deren Herstellung | |
FI950516A0 (fi) | Interferoni-alfa/beta-sitojaproteiini, sen valmistus ja käyttö | |
DE3685044D1 (de) | Analoge interferon-polypeptide, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammensetzungen. | |
DE69738977D1 (de) | Neues fusionsprotein, dafuer kodierendes gen, rekoerwendung | |
FR2761992B1 (fr) | Nouveaux steroides 4-halogenes, leur procede et intermediaires de preparation, leur application comme medicaments et les compositions pharmaceutiques les renfermant |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
GB1A | Change in the ownership or in the address of the owner |