PT1023267E - Compostos de piridilo e composicoes farmaceuticas que os contem - Google Patents
Compostos de piridilo e composicoes farmaceuticas que os contemInfo
- Publication number
- PT1023267E PT1023267E PT98945453T PT98945453T PT1023267E PT 1023267 E PT1023267 E PT 1023267E PT 98945453 T PT98945453 T PT 98945453T PT 98945453 T PT98945453 T PT 98945453T PT 1023267 E PT1023267 E PT 1023267E
- Authority
- PT
- Portugal
- Prior art keywords
- pharmaceutical compositions
- contain
- pyridyl compounds
- compounds
- pyridyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/79—Acids; Esters
- C07D213/80—Acids; Esters in position 3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4418—Non condensed pyridines; Hydrogenated derivatives thereof having a carbocyclic group directly attached to the heterocyclic ring, e.g. cyproheptadine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/443—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with oxygen as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Plural Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH02364/97A CH692199A8 (fr) | 1997-10-09 | 1997-10-09 | Composes pyridiques et compositions pharmaceutique |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT1023267E true PT1023267E (pt) | 2004-01-30 |
Family
ID=4232069
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT98945453T PT1023267E (pt) | 1997-10-09 | 1998-10-07 | Compostos de piridilo e composicoes farmaceuticas que os contem |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US6482841B1 (pt) |
| EP (1) | EP1023267B1 (pt) |
| JP (1) | JP2001519415A (pt) |
| AT (1) | ATE250034T1 (pt) |
| AU (1) | AU747150B2 (pt) |
| CA (1) | CA2306789A1 (pt) |
| CH (1) | CH692199A8 (pt) |
| DE (1) | DE69818286T2 (pt) |
| ES (1) | ES2206989T3 (pt) |
| PT (1) | PT1023267E (pt) |
| WO (1) | WO1999019302A1 (pt) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1162197B1 (de) * | 2000-06-08 | 2004-05-26 | Bayer Chemicals AG | Verfahren zur Herstellung von Pyridinen durch Oxidation von Dihydropyridinen mittels Methylnitrit |
| DE10115945A1 (de) | 2001-03-30 | 2002-10-02 | Bayer Ag | Substituierte 2-Carba-3,5-dicyano-4-aryl-6-aminopyridine und ihre Verwendung |
| US7183410B2 (en) * | 2001-08-02 | 2007-02-27 | Bidachem S.P.A. | Stable polymorph of flibanserin |
| US20030060475A1 (en) * | 2001-08-10 | 2003-03-27 | Boehringer Ingelheim Pharma Kg | Method of using flibanserin for neuroprotection |
| US10675280B2 (en) | 2001-10-20 | 2020-06-09 | Sprout Pharmaceuticals, Inc. | Treating sexual desire disorders with flibanserin |
| UA78974C2 (en) * | 2001-10-20 | 2007-05-10 | Boehringer Ingelheim Pharma | Use of flibanserin for treating disorders of sexual desire |
| US20040048877A1 (en) * | 2002-05-22 | 2004-03-11 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Pharmaceutical compositions containing flibanserin |
| WO2004058711A1 (en) * | 2002-12-30 | 2004-07-15 | Eos Eczacibasi Ozgun Kimyasal Urunler Sanayi Ve Ticaret A.S. | Isolation of dihydropyridine derivative and preparation salts thereof |
| BRPI0607791A2 (pt) * | 2005-03-15 | 2010-03-23 | Lupin Ltd | composiÇÕes farmacÊuticas de amlodipina e benazepril |
| PL1912650T3 (pl) | 2005-08-03 | 2018-01-31 | Sprout Pharmaceuticals Inc | Zastosowanie flibanseryny w leczeniu otyłości |
| WO2007048803A1 (en) | 2005-10-29 | 2007-05-03 | Boehringer Ingelheim International Gmbh | Benzimidazolone derivatives for the treatment of premenstrual and other female sexual disorders |
| CA2642368A1 (en) * | 2006-02-28 | 2007-09-07 | Boehringer Ingelheim International Gmbh | Treatment of prevention of valvular heart disease with flibanserin |
| JP2009536176A (ja) * | 2006-05-09 | 2009-10-08 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 閉経後の性的欲求障害の治療のためのフリバンセリンの使用 |
| US20090312242A1 (en) * | 2006-06-30 | 2009-12-17 | Ramiro Castro | Flibanserin for the treatment of urinary incontinence and related diseases |
| EP2043648A1 (en) * | 2006-07-14 | 2009-04-08 | Boehringer Ingelheim International GmbH | Use of flibanserin for the treatment of sexual disorders in females |
| AR062320A1 (es) | 2006-08-14 | 2008-10-29 | Boehringer Ingelheim Int | Formulaciones de flibanserina y metodo para fabricarlas |
| CL2007002214A1 (es) | 2006-08-14 | 2008-03-07 | Boehringer Ingelheim Int | Composicion farmaceutica en la forma de comprimido, donde al menos la longitud del comprimido en el estado anterior de la aplicacion es al menos 7/12 del diametro pilorico del paciente y despues de ingerirlo en estado alimentado, la longitud del comp |
| CN104721168A (zh) | 2006-08-25 | 2015-06-24 | 贝林格尔·英格海姆国际有限公司 | 控制释放系统及其制造方法 |
| US8304601B2 (en) * | 2007-01-23 | 2012-11-06 | Keiko Fujikawa | Mouse model for eye disease |
| UY31335A1 (es) * | 2007-09-12 | 2009-04-30 | Tratamiento de sintomas vasomotores | |
| CA3011423C (en) * | 2016-01-26 | 2022-01-18 | Ahmet Hacimuftuoglu | N3,n6-bis(2-(5-methoxy-1h-indole-3-yl)ethyl)-2,6-dimethyl-4-(2-nitrophenyl)pyridine-3,5-dicarboxamide and use thereof in the field of neurotoxicity |
| CN109020875B (zh) * | 2018-08-27 | 2020-05-22 | 北京市药品检验所 | 二氢吡啶类化合物脱氢芳构化方法及在药品检测中的用途 |
| CN114206441B (zh) * | 2019-05-31 | 2024-07-02 | R发现有限责任公司 | Drp1-细丝蛋白复合物形成抑制剂 |
| CN112457242B (zh) * | 2020-12-03 | 2021-11-23 | 广州隽沐生物科技股份有限公司 | 一种拉西地平杂质b的制备方法 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3209276A1 (de) * | 1982-03-13 | 1983-09-15 | Bayer Ag, 5090 Leverkusen | Arzneimittel mit antihypoxischer und ischaemie-protektiver wirkung |
| EP0179239A3 (en) * | 1984-09-17 | 1986-08-13 | Sterling Drug Inc. | 7-(pyridinyl)-/-alkyl-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid having antibacterial activity and preparation thereof |
| US4698350A (en) * | 1984-09-17 | 1987-10-06 | Sterling Drug Inc. | 1-ethyl-6-fluoro-1,4-dihydro-7-(2,6-dimethyl-4-pyridinyl)-4-oxo-3-quinolinecarboxylic acid and antibacterial use thereof |
| CA1312611C (en) * | 1987-07-01 | 1993-01-12 | Yamanouchi Pharmaceutical Co., Ltd. | Pyridine derivatives, process for production thereof and pharmaceutical composition containing them |
| GB8905526D0 (en) * | 1989-03-10 | 1989-04-19 | Fujisawa Pharmaceutical Co | N-containing heterocyclic compounds,processes for the preparation thereof and composition comprising the same |
| DE4200714A1 (de) * | 1992-01-14 | 1993-07-15 | Bayer Ag | Spezieller 1,4-dihydropyridin-3,5-dicarbonsaeureester, verfahren zu seiner herstellung und seine pharmazeutische verwendung |
| JP3286645B2 (ja) * | 1993-03-26 | 2002-05-27 | メルシャン株式会社 | 光学活性１，４−ジヒドロピリジン誘導体およびその製造方法 |
| DE4430639A1 (de) * | 1994-08-29 | 1996-03-07 | Bayer Ag | Verwendung von 5-substituierten Pyridin- und Hexahydrochinolin-3-carbonsäurederivaten |
| WO1997027177A2 (en) * | 1996-01-29 | 1997-07-31 | The United States Of America, Represented By The Secretary, Department Of Health And Human Services | Dihydropyridine-, pyridine-, benzopyran-4-one- and triazoloquinazoline derivatives, their preparation and their use as adenosine receptor antagonists |
-
1997
- 1997-10-09 CH CH02364/97A patent/CH692199A8/xx not_active IP Right Cessation
-
1998
- 1998-10-07 DE DE69818286T patent/DE69818286T2/de not_active Expired - Fee Related
- 1998-10-07 JP JP2000515875A patent/JP2001519415A/ja active Pending
- 1998-10-07 AU AU92771/98A patent/AU747150B2/en not_active Ceased
- 1998-10-07 US US09/529,112 patent/US6482841B1/en not_active Expired - Fee Related
- 1998-10-07 AT AT98945453T patent/ATE250034T1/de not_active IP Right Cessation
- 1998-10-07 EP EP98945453A patent/EP1023267B1/en not_active Expired - Lifetime
- 1998-10-07 PT PT98945453T patent/PT1023267E/pt unknown
- 1998-10-07 WO PCT/IB1998/001555 patent/WO1999019302A1/en active IP Right Grant
- 1998-10-07 ES ES98945453T patent/ES2206989T3/es not_active Expired - Lifetime
- 1998-10-07 CA CA002306789A patent/CA2306789A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| AU747150B2 (en) | 2002-05-09 |
| CH692199A5 (fr) | 2002-03-15 |
| WO1999019302A1 (en) | 1999-04-22 |
| US6482841B1 (en) | 2002-11-19 |
| DE69818286D1 (de) | 2003-10-23 |
| EP1023267B1 (en) | 2003-09-17 |
| EP1023267A1 (en) | 2000-08-02 |
| JP2001519415A (ja) | 2001-10-23 |
| CA2306789A1 (en) | 1999-04-22 |
| ES2206989T3 (es) | 2004-05-16 |
| AU9277198A (en) | 1999-05-03 |
| ATE250034T1 (de) | 2003-10-15 |
| CH692199A8 (fr) | 2002-06-14 |
| DE69818286T2 (de) | 2004-07-01 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| PT1023267E (pt) | Compostos de piridilo e composicoes farmaceuticas que os contem | |
| NO971889L (no) | Forbindelser og sammensetninger for levering av aktive midler | |
| BR0112160A (pt) | Agentes antiinflamatórios seletivos para glicocorticóides | |
| EA200300065A1 (ru) | Окисленные сложные эфиры 4-йодфениламинобензгидроксамовых кислот | |
| MD1233C2 (ro) | Derivaţi de eritromicină, procedeu de preparare a lor şi compoziţie farmaceutică pe baza acestora | |
| NZ236589A (en) | A-nor-steroid-3-carboxylic acid derivatives and pharmaceutical compositions | |
| PT896533E (pt) | Pentafluorobenzenosulfonamidas e analogos | |
| FI944217A (fi) | Substituoidut pipekoliinihappojohdannaiset HIV-proteaasin estäjinä | |
| IT1270260B (it) | Derivati dell'acido fosfonico ad attivita' inibitrice delle metallopeptidasi | |
| IT8722343A0 (it) | Derivati di acidi biliari loro preparazione e composizioni farmaceutiche che li contengono. | |
| MX9300779A (es) | 3-(1h-tetrazol-5-y1)-4h-pyrido[1,2-a]pirimidina-4-onas composiciones farmaceuticas que las contienen y su preparacion de las mismas | |
| IT8920169A0 (it) | Derivati di acidi biliari, loro preparazione e composizioni farmaceutiche che li contengono. | |
| WO2001091738A3 (en) | Naaladase inhibitors for treating amyotrophic lateral sclerosis | |
| ATE59294T1 (de) | Stabilisierte arzneimittel. | |
| MD502G2 (ro) | Derivaţi noi ai adenozinei, procedee de preparare a lor, compoziţii farmaceutice ce le conţin | |
| RU94038042A (ru) | Производные гексагидроазепинов, фармацевтическая композиция на их основе и антипсихотропный агент | |
| ATE161837T1 (de) | Benzopyran derivat, seine darstellung und pharmazeutische zusammensetzung, welche dieses enthält | |
| HUP9601526A2 (hu) | Véralvadásgátló hatású peptidil-arginin-aldehid-származékok és a vegyületeket tartalmazó gyógyszerkészítmények | |
| BG88028A (bg) | Амиди на циклометилен-1,2-дикарбоксилни киселини с терапевтична активност,методи за получаването им и фармацевтични състави, които ги съдържат | |
| ES2192789T3 (es) | Derivados de hidrazono-benzazuleno, composiciones farmaceuticas y compuestos intermedios. | |
| FI861329A (fi) | Anvaendning av 4-(isoxazolyl)-tiazol-2-oxaminsyraderivat. | |
| MD554G2 (ro) | Derivaţi noi ai triazolpirimidinelor, antagonişti ai receptorilor angiotensinei II, procedee de preparare a lor, compoziţii farmaceutice care le conţin | |
| BR9707342A (pt) | Dihidrobensofurano e compostos correlatod úteis como agentes antiinflamatórios | |
| IT8621784A0 (it) | Derivati ammidici eterociclici di acidi benzoici sostituiti e composizione terapeutiche che licontengono come principi attivi. | |
| DK0790994T3 (da) | Heterocyclisk substituerede propensyrederivater som NMDA-antagonister |