ATE59294T1 - Stabilisierte arzneimittel. - Google Patents
Stabilisierte arzneimittel.Info
- Publication number
- ATE59294T1 ATE59294T1 AT87309038T AT87309038T ATE59294T1 AT E59294 T1 ATE59294 T1 AT E59294T1 AT 87309038 T AT87309038 T AT 87309038T AT 87309038 T AT87309038 T AT 87309038T AT E59294 T1 ATE59294 T1 AT E59294T1
- Authority
- AT
- Austria
- Prior art keywords
- group
- carbonate
- stabilized
- substituted
- medications
- Prior art date
Links
- 229940079593 drug Drugs 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical compound [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 abstract 2
- CDBYLPFSWZWCQE-UHFFFAOYSA-L Sodium Carbonate Chemical compound [Na+].[Na+].[O-]C([O-])=O CDBYLPFSWZWCQE-UHFFFAOYSA-L 0.000 abstract 2
- UIIMBOGNXHQVGW-UHFFFAOYSA-M Sodium bicarbonate Chemical compound [Na+].OC([O-])=O UIIMBOGNXHQVGW-UHFFFAOYSA-M 0.000 abstract 2
- YNGDWRXWKFWCJY-UHFFFAOYSA-N 1,4-Dihydropyridine Chemical class C1C=CNC=C1 YNGDWRXWKFWCJY-UHFFFAOYSA-N 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 239000012752 auxiliary agent Substances 0.000 abstract 1
- 229910000019 calcium carbonate Inorganic materials 0.000 abstract 1
- 235000010216 calcium carbonate Nutrition 0.000 abstract 1
- FUFJGUQYACFECW-UHFFFAOYSA-L calcium hydrogenphosphate Chemical compound [Ca+2].OP([O-])([O-])=O FUFJGUQYACFECW-UHFFFAOYSA-L 0.000 abstract 1
- 235000019700 dicalcium phosphate Nutrition 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 125000004123 n-propyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])* 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 229910000030 sodium bicarbonate Inorganic materials 0.000 abstract 1
- 235000017557 sodium bicarbonate Nutrition 0.000 abstract 1
- 229910000029 sodium carbonate Inorganic materials 0.000 abstract 1
- 235000017550 sodium carbonate Nutrition 0.000 abstract 1
- 239000007787 solid Substances 0.000 abstract 1
- 239000003381 stabilizer Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2009—Inorganic compounds
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Inorganic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP61241299A JPS6396126A (ja) | 1986-10-13 | 1986-10-13 | 安定化組成物 |
| EP87309038A EP0264259B1 (de) | 1986-10-13 | 1987-10-13 | Stabilisierte Arzneimittel |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE59294T1 true ATE59294T1 (de) | 1991-01-15 |
Family
ID=17072213
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT87309038T ATE59294T1 (de) | 1986-10-13 | 1987-10-13 | Stabilisierte arzneimittel. |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US4906647A (de) |
| EP (1) | EP0264259B1 (de) |
| JP (1) | JPS6396126A (de) |
| KR (1) | KR880004809A (de) |
| AT (1) | ATE59294T1 (de) |
| DE (1) | DE3767114D1 (de) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AR240018A1 (es) * | 1987-10-07 | 1990-01-31 | Merrell Pharma Inc | Procedimiento para preparar una composicion que comprende derivados de piperidinoalcanol. |
| US4929605A (en) * | 1987-10-07 | 1990-05-29 | Merrell Dow Pharmaceuticals Inc. | Pharmaceutical composition for piperidinoalkanol derivatives |
| US5350771A (en) * | 1989-03-22 | 1994-09-27 | Peter K. T. Pang | Method and treatment for hypertension using combination therapy involving exogenous calcium and calcium channel blockers |
| KR0169115B1 (ko) * | 1989-03-22 | 1999-01-15 | 케이 티 팡 피터 | 부갑상선 고혈압성 인자 |
| US5886012A (en) * | 1989-03-22 | 1999-03-23 | Peter K. T. Pang | Method of treatment for disease associated with excessive PHF using combination therapy involving exogenous calcium and calcium channel blockers |
| CA2035841C (en) * | 1990-02-22 | 1996-02-13 | Harry B. Demopoulos | Storage-stable glucosamine sulphate oral dosage forms and methods for their manufacture |
| BE1011045A3 (fr) * | 1997-03-14 | 1999-04-06 | Ucb Sa | Compositions pharmaceutiques pour la liberation controlee de substances actives. |
| SK287105B6 (sk) | 1999-12-20 | 2009-12-07 | Schering Corporation | Dvojvrstvový orálny dávkový prostriedok s predĺženým uvoľňovaním |
| WO2001045668A2 (en) * | 1999-12-20 | 2001-06-28 | Schering Corporation | Stable extended release oral dosage composition comprising pseudoephedrine and desloratadine |
| US7405223B2 (en) | 2000-02-03 | 2008-07-29 | Schering Corporation | Treating allergic and inflammatory conditions |
| WO2001076598A1 (en) * | 2000-04-11 | 2001-10-18 | Sankyo Company, Limited | Stabilized pharmaceutical compositions containing calcium channel blockers |
| US20030235628A1 (en) * | 2001-09-19 | 2003-12-25 | Rajneesh Taneja | Methods and pharmaceutical formulations for protecting pharmaceutical compounds from acidic environments |
| TW200736245A (en) * | 2005-11-29 | 2007-10-01 | Sankyo Co | Acid addition salts of optically active dihydropyridine derivatives |
| TW200806648A (en) * | 2005-11-29 | 2008-02-01 | Sankyo Co | Acid addition salts of dihydropyridine derivatives |
| EP3351240B1 (de) | 2009-05-19 | 2019-04-10 | Celgene Corporation | Formulierungen von 4-amino-2-(2,6-dioxopiperidin-3-yl)isoindolin-1,3-dion |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5547608A (en) * | 1978-09-27 | 1980-04-04 | Key Pharma | Skin medicine |
| JPS56139414A (en) * | 1980-04-01 | 1981-10-30 | Dai Ichi Seiyaku Co Ltd | Stabilizing method of aqueous solution |
| DE3212736A1 (de) * | 1982-04-06 | 1983-10-13 | Bayer Ag, 5090 Leverkusen | Verwendung von dihydropyridinen in arzneimitteln mit salidiuretischer wirkung |
| JPS58185562A (ja) * | 1982-04-22 | 1983-10-29 | Taisho Pharmaceut Co Ltd | １，４−ジヒドロピリジン誘導体 |
| JPS58201726A (ja) * | 1982-05-18 | 1983-11-24 | Meiji Seika Kaisha Ltd | 安定な製剤の製造法 |
| JPS6089420A (ja) * | 1983-10-21 | 1985-05-20 | Taisho Pharmaceut Co Ltd | 血管拡張剤 |
| NL8400911A (nl) * | 1984-03-22 | 1985-10-16 | Dagra Nv | Werkwijze ter bereiding van een farmaceutische toedieningsvorm die tetracycline of doxycyclinezouten bevat. |
| DE3419128A1 (de) * | 1984-05-23 | 1985-11-28 | Bayer Ag, 5090 Leverkusen | Dihydropyridinpraeparate und verfahren zu ihrer herstellung |
| DE3419131A1 (de) * | 1984-05-23 | 1985-11-28 | Bayer Ag, 5090 Leverkusen | Dihydropyridinkombinationspraeparate und verfahren zu ihrer herstellung |
| US4730052A (en) * | 1984-07-13 | 1988-03-08 | Taisho Pharmaceutical Co., Ltd. | Method for preparing unsymmetrical 1,4-dihydropyridine-3,5-dicarboxylic acid diesters |
-
1986
- 1986-10-13 JP JP61241299A patent/JPS6396126A/ja active Pending
-
1987
- 1987-10-01 US US07/103,297 patent/US4906647A/en not_active Expired - Fee Related
- 1987-10-12 KR KR870011258A patent/KR880004809A/ko not_active Ceased
- 1987-10-13 DE DE8787309038T patent/DE3767114D1/de not_active Expired - Lifetime
- 1987-10-13 AT AT87309038T patent/ATE59294T1/de not_active IP Right Cessation
- 1987-10-13 EP EP87309038A patent/EP0264259B1/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| KR880004809A (ko) | 1988-06-27 |
| EP0264259A1 (de) | 1988-04-20 |
| US4906647A (en) | 1990-03-06 |
| JPS6396126A (ja) | 1988-04-27 |
| EP0264259B1 (de) | 1990-12-27 |
| DE3767114D1 (de) | 1991-02-07 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |