PL99858B1 - Sposob wytwarzania nowych pochodnych kwasu 3-aminoindazolokarboksylowego - Google Patents

Sposob wytwarzania nowych pochodnych kwasu 3-aminoindazolokarboksylowego Download PDF

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Publication number
PL99858B1
PL99858B1 PL1975185475A PL18547575A PL99858B1 PL 99858 B1 PL99858 B1 PL 99858B1 PL 1975185475 A PL1975185475 A PL 1975185475A PL 18547575 A PL18547575 A PL 18547575A PL 99858 B1 PL99858 B1 PL 99858B1
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PL
Poland
Prior art keywords
amino
formula
carboxylic acid
trifluoromethylindazole
melting point
Prior art date
Application number
PL1975185475A
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English (en)
Polish (pl)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of PL99858B1 publication Critical patent/PL99858B1/pl

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/54—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
    • C07D231/56—Benzopyrazoles; Hydrogenated benzopyrazoles

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
PL1975185475A 1974-12-13 1975-12-11 Sposob wytwarzania nowych pochodnych kwasu 3-aminoindazolokarboksylowego PL99858B1 (pl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2458965A DE2458965C3 (de) 1974-12-13 1974-12-13 3-Amino-indazol-N-carbonsäure-Derivate, Verfahren zu ihrer Herstellung sowie sie enthaltende Arzneimittel

Publications (1)

Publication Number Publication Date
PL99858B1 true PL99858B1 (pl) 1978-08-31

Family

ID=5933305

Family Applications (1)

Application Number Title Priority Date Filing Date
PL1975185475A PL99858B1 (pl) 1974-12-13 1975-12-11 Sposob wytwarzania nowych pochodnych kwasu 3-aminoindazolokarboksylowego

Country Status (27)

Country Link
US (1) US4051252A (en:Method)
JP (1) JPS5182266A (en:Method)
AT (1) AT343653B (en:Method)
BE (1) BE836528A (en:Method)
CA (1) CA1059523A (en:Method)
CH (1) CH622250A5 (en:Method)
CS (1) CS189731B2 (en:Method)
DD (1) DD125484A5 (en:Method)
DE (1) DE2458965C3 (en:Method)
DK (1) DK137082C (en:Method)
ES (1) ES443429A1 (en:Method)
FI (1) FI753493A7 (en:Method)
FR (1) FR2293928A1 (en:Method)
GB (1) GB1490306A (en:Method)
HK (1) HK52580A (en:Method)
HU (1) HU173557B (en:Method)
IE (1) IE42208B1 (en:Method)
IL (1) IL48642A (en:Method)
KE (1) KE3078A (en:Method)
LU (1) LU73993A1 (en:Method)
NL (1) NL7514521A (en:Method)
NO (1) NO145382C (en:Method)
PL (1) PL99858B1 (en:Method)
SE (1) SE419645B (en:Method)
SU (1) SU604487A3 (en:Method)
YU (1) YU315275A (en:Method)
ZA (1) ZA757777B (en:Method)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4431657A (en) * 1982-05-24 1984-02-14 Ayerst, Mckenna & Harrison Inc. Analgesic compositions consisting of 2H-benzothieno[3,2-c]pyrazol-3-amine derivatives
KR20010086657A (ko) * 2000-03-02 2001-09-15 성재갑 아미노인다졸 유도체 및 이를 함유하는 싸이클린 의존키나아제 저해제 조성물
CN1926132B (zh) * 2000-09-15 2010-12-29 沃泰克斯药物股份有限公司 可用作蛋白激酶抑制剂的吡唑化合物
EP1698627A1 (en) * 2000-09-15 2006-09-06 Vertex Pharmaceuticals Incorporated Pyrazole compounds useful as protein kinase inhibitors
US7473691B2 (en) * 2000-09-15 2009-01-06 Vertex Pharmaceuticals Incorporated Pyrazole compounds useful as protein kinase inhibitors
US6660731B2 (en) 2000-09-15 2003-12-09 Vertex Pharmaceuticals Incorporated Pyrazole compounds useful as protein kinase inhibitors
MXPA03002291A (es) 2000-09-15 2003-06-06 Vertex Pharma Compuestos de pirazol utiles como inhibidores de proteina cinasa.
ATE340172T1 (de) 2000-12-21 2006-10-15 Vertex Pharma Pyrazolverbindungen als protein- kinasehemmer
KR100406634B1 (ko) * 2001-03-12 2003-11-20 주식회사 엘지생명과학 3,5-디아미노인다졸 유도체, 그의 제조방법 및 사이클린의존성 키나아제 저해제로서의 그의 용도
EP1820503B1 (en) 2001-09-26 2012-02-22 Pfizer Italia S.r.l. Aminoindazole derivatives active as kinase inhibitors, process for their preparation and pharmaceutical compositions containing them
WO2003066629A2 (en) * 2002-02-06 2003-08-14 Vertex Pharmaceuticals Incorporated Heteroaryl compounds useful as inhibitors of gsk-3
FR2836915B1 (fr) * 2002-03-11 2008-01-11 Aventis Pharma Sa Derives d'aminoindazoles, procede de preparation et intermediaires de ce procede a titre de medicaments et compositions pharmaceutiques les renfermant
AU2003218215A1 (en) 2002-03-15 2003-09-29 Vertex Pharmaceuticals, Inc. Azolylaminoazines as inhibitors of protein kinases
ES2411655T3 (es) 2002-05-17 2013-07-08 Pfizer Italia S.R.L. Derivados de aminoindazol activos como inhibidores de quinasas, procedimiento para su preparación y composiciones farmacéuticas que los comprenden
MY141867A (en) * 2002-06-20 2010-07-16 Vertex Pharma Substituted pyrimidines useful as protein kinase inhibitors
DE60308387T2 (de) 2002-08-02 2007-09-20 Vertex Pharmaceuticals Inc., Cambridge Pyrazolenthaltende zusammensetzungen und ihre verwendung als gsk-3 inhibitoren
WO2004041285A1 (en) * 2002-10-31 2004-05-21 Amgen Inc. Antiinflammation agents
WO2004072029A2 (en) 2003-02-06 2004-08-26 Vertex Pharmaceuticals Incorporated Pyrazolopyridazines useful as inhibitors of protein kinases
WO2005056547A2 (en) * 2003-12-04 2005-06-23 Vertex Pharmaceuticals Incorporated Quinoxalines useful as inhibitors of protein kinases
DE102004005172A1 (de) * 2004-02-02 2005-08-18 Aventis Pharma Deutschland Gmbh Indazolderivate als Inhibitoren der Hormon Sensitiven Lipase
ATE542814T1 (de) 2005-08-18 2012-02-15 Vertex Pharma Pyrazinkinaseinhibitoren
AR056763A1 (es) * 2005-11-03 2007-10-24 Vertex Pharma Aminopirimidinas sustituidas con tiazol o pirazol,utiles como agentes anticancer y composiciones farmaceuticas que las contienen.
KR101118932B1 (ko) * 2006-04-14 2012-02-27 아보트 러보러터리즈 바닐로이드 서브타입 1(ｖｒ1) 수용체를 억제하는 인다졸릴우레아의 제조방법
WO2008057940A1 (en) 2006-11-02 2008-05-15 Vertex Pharmaceuticals Incorporated Aminopyridines and aminopyrimidines useful as inhibitors of protein kinases
MX2009006690A (es) 2006-12-19 2009-07-31 Vertex Pharma Aminopirimidinas utiles como inhibidores de proteinas cinasas.
JP2010520887A (ja) 2007-03-09 2010-06-17 バーテックス ファーマシューティカルズ インコーポレイテッド 蛋白キナーゼの阻害剤として有用なアミノピリジン
MX2009009590A (es) 2007-03-09 2009-11-10 Vertex Pharma Aminopirimidinas utiles como inhibidores de proteinas cinasas.
CA2680029A1 (en) 2007-03-09 2008-09-18 Vertex Pharmaceuticals Incorporated Aminopyrimidines useful as inhibitors of protein kinases
EP2146982A2 (en) 2007-04-13 2010-01-27 Vertex Pharmaceuticals Incorporated Aminopyrimidines useful as kinase inhibitors
EP2152696B1 (en) 2007-05-02 2014-09-24 Vertex Pharmaceuticals Incorporated Aminopyrimidines useful as kinase inhibitors
CA2685876A1 (en) * 2007-05-02 2008-11-13 Vertex Pharmaceuticals Incorporated Thiazoles and pyrazoles useful as kinase inhibitors
JP5572087B2 (ja) * 2007-05-02 2014-08-13 バーテックス ファーマシューティカルズ インコーポレイテッド キナーゼ阻害として有用なアミノピリミジン
AU2008257044A1 (en) * 2007-05-24 2008-12-04 Vertex Pharmaceuticals Incorporated Thiazoles and pyrazoles useful as kinase inhibitors
NZ582879A (en) * 2007-07-31 2012-03-30 Vertex Pharma Process for preparing 5-fluoro-1h-pyrazolo [3, 4-b] pyridin-3-amine and derivatives thereof
MX2011002312A (es) * 2008-09-03 2011-04-26 Vertex Pharma Co-cristales y formulaciones farmaceuticas que comprenden los mismos.
DE102009004245A1 (de) 2009-01-09 2010-07-15 Bayer Schering Pharma Aktiengesellschaft Neue anellierte, Heteroatom-verbrückte Pyrazol- und Imidazol-Derivate und ihre Verwendung
AU2013293650B2 (en) 2012-07-24 2017-05-25 Bial- Portela & Ca, S.A. Urea compounds and their use as enzyme inhibitors
EP2882712A2 (en) * 2012-07-27 2015-06-17 BIAL - Portela & Cª S.A. Process for the synthesis of substituted urea compounds
WO2015012708A1 (en) 2013-07-24 2015-01-29 BIAL - PORTELA & Cª, S.A. Imidazolecarboxamides and their use as faah inhibitors

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3133081A (en) * 1964-05-12 J-aminoindazole derivatives
CH397698A (de) * 1961-09-08 1965-08-31 Siegfried Ag Verfahren zur Herstellung neuer 1-Carbamyl-indazole
US3277100A (en) * 1963-05-31 1966-10-04 Du Pont Novel substituted pyrazoles
NL6707299A (en:Method) * 1966-07-16 1968-01-17
DE1770649A1 (de) * 1968-06-15 1971-11-11 Bayer Ag Substituierte 3-Amino-indazole

Also Published As

Publication number Publication date
DE2458965C3 (de) 1979-10-11
NL7514521A (nl) 1976-06-15
DK137082B (da) 1978-01-16
CA1059523A (en) 1979-07-31
NO145382B (no) 1981-11-30
KE3078A (en) 1980-10-03
IE42208B1 (en) 1980-06-18
CS189731B2 (en) 1979-04-30
JPS5182266A (en) 1976-07-19
DE2458965A1 (de) 1976-06-16
DD125484A5 (en:Method) 1977-04-20
IE42208L (en) 1976-06-13
FI753493A7 (en:Method) 1976-06-14
LU73993A1 (en:Method) 1976-11-11
SE7513990L (sv) 1976-06-14
BE836528A (fr) 1976-06-11
SE419645B (sv) 1981-08-17
IL48642A (en) 1979-12-30
DE2458965B2 (de) 1979-02-22
AU8717075A (en) 1977-06-09
GB1490306A (en) 1977-11-02
AT343653B (de) 1978-06-12
FR2293928B1 (en:Method) 1979-09-21
ATA939775A (de) 1977-10-15
SU604487A3 (ru) 1978-04-25
NO754024L (en:Method) 1976-06-15
DK137082C (da) 1978-06-19
HK52580A (en) 1980-09-26
NO145382C (no) 1982-03-10
FR2293928A1 (fr) 1976-07-09
CH622250A5 (en:Method) 1981-03-31
YU315275A (en) 1982-02-28
ES443429A1 (es) 1977-04-16
ZA757777B (en) 1976-11-24
IL48642A0 (en) 1976-02-29
US4051252A (en) 1977-09-27
DK567275A (da) 1976-06-14
HU173557B (hu) 1979-06-28

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