PL372809A1 - Podstawione pochodne 1,3-difenyloprop-2-en-1-onu,sposób otrzymywania i zastosowanie podstawionych pochodnych 1,3-difenyloprop-2-enu-1-onu - Google Patents

Podstawione pochodne 1,3-difenyloprop-2-en-1-onu,sposób otrzymywania i zastosowanie podstawionych pochodnych 1,3-difenyloprop-2-enu-1-onu

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Publication number
PL372809A1
PL372809A1 PL03372809A PL37280903A PL372809A1 PL 372809 A1 PL372809 A1 PL 372809A1 PL 03372809 A PL03372809 A PL 03372809A PL 37280903 A PL37280903 A PL 37280903A PL 372809 A1 PL372809 A1 PL 372809A1
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PL
Poland
Prior art keywords
derivatives
diphenylprop
substituted
preparation
relates
Prior art date
Application number
PL03372809A
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English (en)
Other versions
PL207362B1 (pl
Inventor
Jamila Najib
Karine Caumont-Bertrand
Original Assignee
Genfit
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Genfit filed Critical Genfit
Publication of PL372809A1 publication Critical patent/PL372809A1/pl
Publication of PL207362B1 publication Critical patent/PL207362B1/pl

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
    • C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/52—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/22—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and doubly-bound oxygen atoms bound to the same carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/30—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/30—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
    • C07C67/333—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton
    • C07C67/343—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C07C69/67—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of saturated acids
    • C07C69/708—Ethers
    • C07C69/712—Ethers the hydroxy group of the ester being etherified with a hydroxy compound having the hydroxy group bound to a carbon atom of a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
    • C07C69/738—Esters of keto-carboxylic acids or aldehydo-carboxylic acids

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrane Compounds (AREA)

Abstract

Wynalazek dotyczy nowych podstawionych pochodnych 1,3-difenyloprop-2-en-1-onu, farmaceutycznych kompozycji zawierających te pochodne, ich zastosowań terapeutycznych, w szczególności do leczenia niedokrwienia mózgowego. Wynalazek dotyczy również sposobu otrzymywania tych pochodnych.
PL372809A 2002-07-08 2003-07-08 Podstawione pochodne 1,3-difenyloprop-2-en-1-onu, sposób otrzymywania tych związków , kompozycje farmaceutyczne zawierające te związki oraz zastosowanie tych związków PL207362B1 (pl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0208571A FR2841900B1 (fr) 2002-07-08 2002-07-08 Nouveaux derives de 1,3-diphenylprop-2-en-1-one substitues, preparation et utilisations

Publications (2)

Publication Number Publication Date
PL372809A1 true PL372809A1 (pl) 2005-08-08
PL207362B1 PL207362B1 (pl) 2010-12-31

Family

ID=29725283

Family Applications (1)

Application Number Title Priority Date Filing Date
PL372809A PL207362B1 (pl) 2002-07-08 2003-07-08 Podstawione pochodne 1,3-difenyloprop-2-en-1-onu, sposób otrzymywania tych związków , kompozycje farmaceutyczne zawierające te związki oraz zastosowanie tych związków

Country Status (24)

Country Link
US (3) US7943661B2 (pl)
EP (1) EP1525177B1 (pl)
JP (1) JP4575771B2 (pl)
KR (1) KR100974577B1 (pl)
CN (1) CN100548960C (pl)
AT (1) ATE365703T1 (pl)
AU (1) AU2003264698B2 (pl)
BR (1) BRPI0312398B8 (pl)
CA (1) CA2490986C (pl)
CY (1) CY1108085T1 (pl)
DE (1) DE60314633T2 (pl)
DK (1) DK1525177T3 (pl)
EA (1) EA011090B1 (pl)
ES (1) ES2287528T3 (pl)
FR (1) FR2841900B1 (pl)
IL (2) IL165696A0 (pl)
MX (1) MXPA05000427A (pl)
NO (1) NO329700B1 (pl)
NZ (1) NZ538051A (pl)
PL (1) PL207362B1 (pl)
PT (1) PT1525177E (pl)
SI (1) SI1525177T1 (pl)
WO (1) WO2004005233A1 (pl)
ZA (1) ZA200501082B (pl)

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FR2841900B1 (fr) 2002-07-08 2007-03-02 Genfit S A Nouveaux derives de 1,3-diphenylprop-2-en-1-one substitues, preparation et utilisations
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EP1701938B1 (fr) * 2004-01-08 2012-07-25 Genfit Composes derives de 1,3-diphenylprop-2-en-1-one, preparation et utilisations
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Also Published As

Publication number Publication date
CN100548960C (zh) 2009-10-14
BRPI0312398B8 (pt) 2021-05-25
US7943661B2 (en) 2011-05-17
ES2287528T3 (es) 2007-12-16
US7566737B2 (en) 2009-07-28
DE60314633D1 (de) 2007-08-09
EA200500169A1 (ru) 2005-06-30
PL207362B1 (pl) 2010-12-31
IL165696A (en) 2012-09-24
CY1108085T1 (el) 2014-02-12
BR0312398A (pt) 2005-04-12
ZA200501082B (en) 2007-01-31
MXPA05000427A (es) 2005-09-30
JP2005532385A (ja) 2005-10-27
JP4575771B2 (ja) 2010-11-04
CA2490986A1 (fr) 2004-01-15
NO329700B1 (no) 2010-12-06
KR20050025327A (ko) 2005-03-14
CA2490986C (fr) 2012-09-18
FR2841900B1 (fr) 2007-03-02
NO20045301L (no) 2005-02-04
PT1525177E (pt) 2007-09-06
NZ538051A (en) 2007-11-30
AU2003264698A1 (en) 2004-01-23
BRPI0312398B1 (pt) 2016-11-08
WO2004005233A1 (fr) 2004-01-15
US20070032543A1 (en) 2007-02-08
IL165696A0 (en) 2006-01-15
US20110190515A1 (en) 2011-08-04
AU2003264698B2 (en) 2009-09-17
DE60314633T2 (de) 2008-02-28
EP1525177A1 (fr) 2005-04-27
ATE365703T1 (de) 2007-07-15
FR2841900A1 (fr) 2004-01-09
KR100974577B1 (ko) 2010-08-06
US8058308B2 (en) 2011-11-15
SI1525177T1 (sl) 2007-10-31
US20050176808A1 (en) 2005-08-11
EA011090B1 (ru) 2008-12-30
EP1525177B1 (fr) 2007-06-27
DK1525177T3 (da) 2007-10-22
CN1668565A (zh) 2005-09-14

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