PL371679A1 - A process for the preparation of modafinil - Google Patents
A process for the preparation of modafinilInfo
- Publication number
- PL371679A1 PL371679A1 PL03371679A PL37167903A PL371679A1 PL 371679 A1 PL371679 A1 PL 371679A1 PL 03371679 A PL03371679 A PL 03371679A PL 37167903 A PL37167903 A PL 37167903A PL 371679 A1 PL371679 A1 PL 371679A1
- Authority
- PL
- Poland
- Prior art keywords
- preparation
- modafinil
- diphenylmethyl
- sulfenyl
- sulfinyl
- Prior art date
Links
- YFGHCGITMMYXAQ-UHFFFAOYSA-N 2-[(diphenylmethyl)sulfinyl]acetamide Chemical compound C=1C=CC=CC=1C(S(=O)CC(=O)N)C1=CC=CC=C1 YFGHCGITMMYXAQ-UHFFFAOYSA-N 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 238000002360 preparation method Methods 0.000 title abstract 2
- 229960001165 modafinil Drugs 0.000 title 1
- 150000001408 amides Chemical class 0.000 abstract 1
- 238000001212 derivatisation Methods 0.000 abstract 1
- 230000003647 oxidation Effects 0.000 abstract 1
- 238000007254 oxidation reaction Methods 0.000 abstract 1
- TVJWZSWDEPQVDV-UHFFFAOYSA-M sodium;2-benzhydrylsulfanylacetate Chemical compound [Na+].C=1C=CC=CC=1C(SCC(=O)[O-])C1=CC=CC=C1 TVJWZSWDEPQVDV-UHFFFAOYSA-M 0.000 abstract 1
- 150000003462 sulfoxides Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C315/00—Preparation of sulfones; Preparation of sulfoxides
- C07C315/02—Preparation of sulfones; Preparation of sulfoxides by formation of sulfone or sulfoxide groups by oxidation of sulfides, or by formation of sulfone groups by oxidation of sulfoxides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C315/00—Preparation of sulfones; Preparation of sulfoxides
- C07C315/04—Preparation of sulfones; Preparation of sulfoxides by reactions not involving the formation of sulfone or sulfoxide groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
- C07C317/44—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Liquid Crystal (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Electrochromic Elements, Electrophoresis, Or Variable Reflection Or Absorption Elements (AREA)
- Optical Modulation, Optical Deflection, Nonlinear Optics, Optical Demodulation, Optical Logic Elements (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT2002MI000991A ITMI20020991A1 (it) | 2002-05-10 | 2002-05-10 | Procedimento per la sintesi del modafinil |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL371679A1 true PL371679A1 (en) | 2005-06-27 |
Family
ID=11449867
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL03371679A PL371679A1 (en) | 2002-05-10 | 2003-04-23 | A process for the preparation of modafinil |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US7057068B2 (https=) |
| EP (1) | EP1503983B1 (https=) |
| JP (1) | JP4351626B2 (https=) |
| KR (1) | KR20040108789A (https=) |
| AT (1) | ATE364593T1 (https=) |
| AU (1) | AU2003227668A1 (https=) |
| CA (1) | CA2485428A1 (https=) |
| DE (1) | DE60314410T2 (https=) |
| DK (1) | DK1503983T3 (https=) |
| EA (1) | EA007327B1 (https=) |
| ES (1) | ES2286429T3 (https=) |
| IL (1) | IL165121A0 (https=) |
| IT (1) | ITMI20020991A1 (https=) |
| MX (1) | MXPA04011141A (https=) |
| PL (1) | PL371679A1 (https=) |
| PT (1) | PT1503983E (https=) |
| WO (1) | WO2003095423A1 (https=) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CZ2003529A3 (cs) | 2000-07-27 | 2003-09-17 | Teva Pharmaceutical Industries Ltd. | Krystalický a čistý modafinil a postup jeho přípravy |
| ITMI20051971A1 (it) * | 2005-10-18 | 2007-04-19 | Dipharma Spa | Procedimento per la preparazione di - modafinil |
| US20070293702A1 (en) * | 2006-02-21 | 2007-12-20 | Viviana Braude | Novel crystalline forms of armodafinil and preparation thereof |
| WO2007103221A2 (en) * | 2006-03-01 | 2007-09-13 | Teva Pharmaceutical Industries Ltd. | An improved process for the preparation of armodafinil |
| KR20090031618A (ko) * | 2006-07-12 | 2009-03-26 | 엘란 코포레이션, 피엘씨 | 나노입자형 모다피닐 제제 |
| WO2009025791A2 (en) * | 2007-08-16 | 2009-02-26 | Teva Pharmaceutical Industries Ltd. | Purification of armodafinil |
| EP1911739A3 (en) | 2007-11-05 | 2008-09-17 | Dipharma Francis S.r.l. | Crystalline form of (S)-2-phenylethylammonium (R)-diphenyl-methanesulphinyl-acetate |
| US9616068B2 (en) | 2014-10-27 | 2017-04-11 | Pohela LLC | Animal training using cognitive enhancement |
| CN114044730B (zh) * | 2021-11-26 | 2024-04-23 | 台州学院 | 一种亚砜类化合物的合成方法 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE221261C (https=) * | ||||
| DE2546319C2 (de) * | 1975-10-16 | 1986-02-27 | Dr. Karl Thomae Gmbh, 7950 Biberach | Cyclohexylphenyl-Derivate, Verfahren zu deren Herstellung und diese enthaltende Mittel |
| GB1584462A (en) * | 1977-03-31 | 1981-02-11 | Lafon Labor | N-diaryl-malonamide and diarylmethyl-sulphinyl-acetamide derivatives and pharmaceutical compositions containing them |
| FR2593809B1 (fr) * | 1986-01-31 | 1988-07-22 | Lafon Labor | Benzhydrylsulfinylacetamide, procede de preparation et utilisation en therapeutique |
| US4964893A (en) * | 1986-04-17 | 1990-10-23 | Monsanto Company | Benzhydryl compounds as herbicide antidotes |
| CZ2003529A3 (cs) | 2000-07-27 | 2003-09-17 | Teva Pharmaceutical Industries Ltd. | Krystalický a čistý modafinil a postup jeho přípravy |
-
2002
- 2002-05-10 IT IT2002MI000991A patent/ITMI20020991A1/it unknown
-
2003
- 2003-04-23 MX MXPA04011141A patent/MXPA04011141A/es active IP Right Grant
- 2003-04-23 CA CA002485428A patent/CA2485428A1/en not_active Abandoned
- 2003-04-23 DK DK03725083T patent/DK1503983T3/da active
- 2003-04-23 KR KR10-2004-7018040A patent/KR20040108789A/ko not_active Withdrawn
- 2003-04-23 EA EA200401235A patent/EA007327B1/ru not_active IP Right Cessation
- 2003-04-23 WO PCT/EP2003/004229 patent/WO2003095423A1/en not_active Ceased
- 2003-04-23 PL PL03371679A patent/PL371679A1/xx not_active IP Right Cessation
- 2003-04-23 JP JP2004503444A patent/JP4351626B2/ja not_active Expired - Fee Related
- 2003-04-23 AU AU2003227668A patent/AU2003227668A1/en not_active Abandoned
- 2003-04-23 US US10/513,881 patent/US7057068B2/en not_active Expired - Fee Related
- 2003-04-23 DE DE60314410T patent/DE60314410T2/de not_active Expired - Lifetime
- 2003-04-23 ES ES03725083T patent/ES2286429T3/es not_active Expired - Lifetime
- 2003-04-23 PT PT03725083T patent/PT1503983E/pt unknown
- 2003-04-23 EP EP03725083A patent/EP1503983B1/en not_active Expired - Lifetime
- 2003-04-23 AT AT03725083T patent/ATE364593T1/de not_active IP Right Cessation
-
2004
- 2004-11-09 IL IL16512104A patent/IL165121A0/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JP4351626B2 (ja) | 2009-10-28 |
| ES2286429T3 (es) | 2007-12-01 |
| JP2005525420A (ja) | 2005-08-25 |
| WO2003095423A1 (en) | 2003-11-20 |
| US7057068B2 (en) | 2006-06-06 |
| IL165121A0 (en) | 2005-12-18 |
| EA007327B1 (ru) | 2006-08-25 |
| MXPA04011141A (es) | 2005-07-01 |
| EP1503983A1 (en) | 2005-02-09 |
| AU2003227668A1 (en) | 2003-11-11 |
| DE60314410D1 (de) | 2007-07-26 |
| DE60314410T2 (de) | 2008-02-14 |
| DK1503983T3 (da) | 2007-09-10 |
| US20050154063A1 (en) | 2005-07-14 |
| CA2485428A1 (en) | 2003-11-20 |
| EA200401235A1 (ru) | 2005-06-30 |
| PT1503983E (pt) | 2007-07-31 |
| ATE364593T1 (de) | 2007-07-15 |
| KR20040108789A (ko) | 2004-12-24 |
| EP1503983B1 (en) | 2007-06-13 |
| ITMI20020991A0 (it) | 2002-05-10 |
| ITMI20020991A1 (it) | 2003-11-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| VOID | Decisions declaring the decisions on the grant of the patent lapsed |