PL370714A1 - Pochodne 6-O-acylo-ketolidowe erytromycyny użyteczne jako środki przeciwbakteryjne - Google Patents

Pochodne 6-O-acylo-ketolidowe erytromycyny użyteczne jako środki przeciwbakteryjne

Info

Publication number
PL370714A1
PL370714A1 PL02370714A PL37071402A PL370714A1 PL 370714 A1 PL370714 A1 PL 370714A1 PL 02370714 A PL02370714 A PL 02370714A PL 37071402 A PL37071402 A PL 37071402A PL 370714 A1 PL370714 A1 PL 370714A1
Authority
PL
Poland
Prior art keywords
erythromycine
antibacterials
acyl
useful
ketolide derivatives
Prior art date
Application number
PL02370714A
Other languages
English (en)
Inventor
Todd C. Henninger
Mark J. Macielag
Manomi A. Tennakoon
Xiaodong Xu
Original Assignee
Ortho-Mcneil Pharmaceutical, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ortho-Mcneil Pharmaceutical, Inc. filed Critical Ortho-Mcneil Pharmaceutical, Inc.
Publication of PL370714A1 publication Critical patent/PL370714A1/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
PL02370714A 2001-12-05 2002-11-21 Pochodne 6-O-acylo-ketolidowe erytromycyny użyteczne jako środki przeciwbakteryjne PL370714A1 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US33856601P 2001-12-05 2001-12-05
US39251302P 2002-06-28 2002-06-28

Publications (1)

Publication Number Publication Date
PL370714A1 true PL370714A1 (pl) 2005-05-30

Family

ID=26991254

Family Applications (1)

Application Number Title Priority Date Filing Date
PL02370714A PL370714A1 (pl) 2001-12-05 2002-11-21 Pochodne 6-O-acylo-ketolidowe erytromycyny użyteczne jako środki przeciwbakteryjne

Country Status (16)

Country Link
US (1) US6825170B2 (pl)
EP (1) EP1453847A1 (pl)
JP (1) JP2005511752A (pl)
CN (1) CN1585775A (pl)
AR (1) AR038005A1 (pl)
AU (1) AU2002346475A1 (pl)
BR (1) BR0214748A (pl)
CA (1) CA2469304A1 (pl)
HU (1) HUP0500018A3 (pl)
IL (1) IL162292A0 (pl)
MX (1) MXPA04005424A (pl)
NZ (1) NZ533282A (pl)
PL (1) PL370714A1 (pl)
RU (1) RU2004117082A (pl)
TW (1) TW200418497A (pl)
WO (1) WO2003050132A1 (pl)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005531603A (ja) * 2002-05-31 2005-10-20 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ ３−デスクラジノシル−６−ｏ−カルバモイルおよび６−ｏ−カルボノイルマクロライド抗菌剤
WO2004078771A1 (ja) * 2003-03-07 2004-09-16 Taisho Pharmaceutical Co., Ltd. ２－フルオロ－６－ｏ－置換ケトライド誘導体
US20050250713A1 (en) * 2004-04-26 2005-11-10 Bin Zhu 11,12-Cyclic thiocarbamate macrolide antibacterial agents
EP2129225B1 (en) * 2007-04-03 2012-12-05 E. I. Du Pont de Nemours and Company Substituted benzene fungicides
DE102009004061A1 (de) 2009-01-08 2010-07-15 Merck Patent Gmbh Pyridazinonderivate
BR112013009823A2 (pt) 2010-10-22 2016-07-05 Bayer Ip Gmbh novos compostos heterocíclicos como pesticidas
CN103958525A (zh) 2011-11-30 2014-07-30 埃科特莱茵药品有限公司 3,7-二取代八氢-2H-吡啶并[4,3-e][1,3]噁嗪-2-酮抗生素
JP6437523B2 (ja) 2013-04-04 2018-12-12 プレジデント アンド フェローズ オブ ハーバード カレッジ マクロライドならびにそれらの調製および使用の方法
AR097617A1 (es) 2013-09-13 2016-04-06 Actelion Pharmaceuticals Ltd Derivados antibacterianos del 2h-indazol
US10633407B2 (en) 2014-10-08 2020-04-28 President And Fellows Of Harvard College 14-membered ketolides and methods of their preparation and use
EP3273969A4 (en) 2015-03-25 2018-11-21 President and Fellows of Harvard College Macrolides with modified desosamine sugars and uses thereof
CN110028447B (zh) * 2019-05-17 2022-10-14 济南大学 一种2-一氟甲基喹啉衍生物的制备方法

Family Cites Families (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8521402D0 (en) 1985-08-28 1985-10-02 Beecham Group Plc Chemical compounds
IL114589A (en) 1990-11-21 1999-12-22 Roussel Uclaf Intermediates for the preparation of the history of erythromycin
US5559256A (en) 1992-07-20 1996-09-24 E. R. Squibb & Sons, Inc. Aminediol protease inhibitors
US5780473A (en) 1995-02-06 1998-07-14 Bristol-Myers Squibb Company Substituted biphenyl sulfonamide endothelin antagonists
ES2218604T3 (es) 1995-11-08 2004-11-16 Abbott Laboratories Derivados triciclicos de eritromicina.
EP0906103A1 (en) 1995-12-29 1999-04-07 Smithkline Beecham Corporation Vitronectin receptor antagonists
DE69710731T2 (de) 1996-07-17 2002-10-24 Novartis Ag Anilinopeptid-derivate
UA51730C2 (uk) 1996-09-04 2002-12-16 Ебботт Лабораторіз 6-o-заміщені кетоліди з антибактеріальною активністю, спосіб їх одержання (варіанти), фармацевтична композиція та спосіб регулювання бактеріальної інфекції у ссавців
KR100523679B1 (ko) 1996-09-04 2005-10-26 아보트 러보러터리즈 항균 활성을 지닌 6-ｏ-치환된 케톨라이드
UA56197C2 (uk) 1996-11-08 2003-05-15 Зенека Лімітед Гетероциклічні похідні
UA59384C2 (uk) 1996-12-20 2003-09-15 Пфайзер, Інк. Похідні сульфонамідів та амідів як агоністи простагландину, фармацевтична композиція та способи лікування на їх основі
US6034069A (en) 1997-09-30 2000-03-07 Abbott Laboratories 3-'N-modified 6-O-substituted erythromycin ketolide derivatives having antibacterial activity
CO4990960A1 (es) 1997-10-29 2000-12-26 Abbott Lab Derivados de cetolidos 2-halo-6-o sustituidos
AR015986A1 (es) 1997-10-29 2001-05-30 Abbott Lab Derivados de eritromicina puenteados en 6,11, composiciones farmaceuticas que los contienen, su uso para la manufactura de un medicamento y procedimientospara su preparacion
AP1060A (en) 1998-01-02 2002-04-23 Pfizer Prod Inc Novel erythromycin derivatives.
US5992683A (en) 1998-08-31 1999-11-30 Kimberly-Clark Worldwide, Inc. Clip lift for sheet dispensing system
US6458771B1 (en) 1999-04-16 2002-10-01 Ortho-Mcneil Pharmaceutical, Inc. Ketolide antibacterials
US6590083B1 (en) 1999-04-16 2003-07-08 Ortho-Mcneil Pharmaceutical, Inc. Ketolide antibacterials
ATE340183T1 (de) 1999-04-16 2006-10-15 Kosan Biosciences Inc Antiinfektiöse makrolidderivate
US6355620B1 (en) 1999-05-14 2002-03-12 Abbott Laboratories C-2 modified erythromycin derivatives
CN1351608A (zh) 1999-05-24 2002-05-29 辉瑞产品公司 13－甲基红霉素衍生物
ATE250076T1 (de) * 1999-06-07 2003-10-15 Abbott Lab 6-o-carbamat ketolide derivate
ES2306674T3 (es) * 1999-12-02 2008-11-16 Abbott Laboratories Derivados cetolidos 6-o-alquil-2-nor-2-sustituidos.
EP1114826A3 (en) 1999-12-29 2001-10-31 Pfizer Products Inc. Novel antibacterial and prokinetic macrolides
EP1146051A3 (en) 2000-04-10 2001-10-31 Pfizer Products Inc. Erythromycin A derivatives
UY26964A1 (es) 2000-10-16 2002-06-20 Abbott Lab Derivados de eritromicina 6-0-sustituidos con mayor tolerancia gastrointestinal
US6472372B1 (en) * 2000-12-06 2002-10-29 Ortho-Mcneil Pharmaceuticals, Inc. 6-O-Carbamoyl ketolide antibacterials
WO2003090760A1 (en) 2002-04-25 2003-11-06 Abbott Laboratories Oxolide antibacterials
JP2005530758A (ja) 2002-04-30 2005-10-13 アボット・ラボラトリーズ 三環式マクロライド系抗菌化合物

Also Published As

Publication number Publication date
US6825170B2 (en) 2004-11-30
US20030220272A1 (en) 2003-11-27
IL162292A0 (en) 2005-11-20
CN1585775A (zh) 2005-02-23
HUP0500018A3 (en) 2009-09-28
TW200418497A (en) 2004-10-01
HUP0500018A2 (en) 2006-09-28
JP2005511752A (ja) 2005-04-28
RU2004117082A (ru) 2005-04-10
AU2002346475A1 (en) 2003-06-23
BR0214748A (pt) 2004-11-23
NZ533282A (en) 2006-09-29
MXPA04005424A (es) 2005-06-20
EP1453847A1 (en) 2004-09-08
WO2003050132A1 (en) 2003-06-19
CA2469304A1 (en) 2003-06-19
AR038005A1 (es) 2004-12-22

Similar Documents

Publication Publication Date Title
IL156329A0 (en) 6-o-carbamoyl ketolide derivatives of erythromycin useful as antibacterials
HK1208446A1 (en) Derivatives of uk-2a uk-2a
HK1066218A1 (en) Qunazoline derivatives as antitumor agents
AU2002243969A1 (en) Rod to rod connector
TWI318880B (en) Azalide antibiotic compositions
IL145976A0 (en) Ketolide antibacterials
IL161996A0 (en) Directly compressible formulations of azithromycin
IL161710A0 (en) Macrolides
PL362005A1 (pl) Ketolidowe środki przeciwbakteryjne
IL162292A0 (en) 6-O-acyl ketolide derivatives of erythromycine useful as antibacterials
IL158236A0 (en) Pharmaceutical compositions containing azithromycin and derivatives thereof
AU2002330717A1 (en) Monosaccharide derivatives
AU2003293635A1 (en) 4'' - modified erythromycin derivatives
PL369674A1 (pl) Pochodne pirazolu jako psychofarmaceutyki
IL161560A0 (en) Anthelmintic compositions containing milbemycin derivatives
AU2002350942A8 (en) Imidazolidineacetic acid derivatives
ZA200507475B (en) Derivatives of azithromycin
AU2001214115A1 (en) Process for the preparation of anhydrous azithromycin
AU2002317415A1 (en) Azalide antibiotic compositions
ZA200405252B (en) 6-O-Acyl ketolide derivatives of erythromycine useful as antibacterials.
HUP0402108A3 (en) Macrolides containing pharmaceutical compositions
SI1638984T1 (sl) Monosaharidni derivati avermektina B1
AU2002346601A1 (en) Novel 11-o-substituted ketolide derivatives
AU2002232183A1 (en) 12- and 13-modified novel 16-membered macrolide derivatives
AU2003253701A1 (en) 11-c-substituted derivatives of clarithromycin

Legal Events

Date Code Title Description
REFS Decisions on refusal to grant patents (taken after the publication of the particulars of the applications)