PL364521A1 - Non-peptide ccr1 receptor antagonists in combination with cyclosporin a for the treatment of heart transplant rejection - Google Patents

Non-peptide ccr1 receptor antagonists in combination with cyclosporin a for the treatment of heart transplant rejection

Info

Publication number
PL364521A1
PL364521A1 PL01364521A PL36452101A PL364521A1 PL 364521 A1 PL364521 A1 PL 364521A1 PL 01364521 A PL01364521 A PL 01364521A PL 36452101 A PL36452101 A PL 36452101A PL 364521 A1 PL364521 A1 PL 364521A1
Authority
PL
Poland
Prior art keywords
cyclosporin
transplant rejection
heart transplant
treatment
combination
Prior art date
Application number
PL01364521A
Other languages
English (en)
Polish (pl)
Inventor
Richard Horuk
Original Assignee
Schering Aktiengesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Aktiengesellschaft filed Critical Schering Aktiengesellschaft
Publication of PL364521A1 publication Critical patent/PL364521A1/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13Cyclosporins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Transplantation (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PL01364521A 2000-07-31 2001-07-31 Non-peptide ccr1 receptor antagonists in combination with cyclosporin a for the treatment of heart transplant rejection PL364521A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US22205300P 2000-07-31 2000-07-31
US23128200P 2000-09-08 2000-09-08
US09/915,411 US6740636B2 (en) 2000-07-31 2001-07-25 Non-peptide CCR1 receptor antagonists in combination with cyclosporin A for the treatment of heart transplant rejection

Publications (1)

Publication Number Publication Date
PL364521A1 true PL364521A1 (en) 2004-12-13

Family

ID=27397025

Family Applications (1)

Application Number Title Priority Date Filing Date
PL01364521A PL364521A1 (en) 2000-07-31 2001-07-31 Non-peptide ccr1 receptor antagonists in combination with cyclosporin a for the treatment of heart transplant rejection

Country Status (28)

Country Link
US (1) US6740636B2 (pt)
EP (1) EP1305047B1 (pt)
JP (1) JP2004530630A (pt)
KR (1) KR20030048000A (pt)
CN (1) CN1655818A (pt)
AT (1) ATE330634T1 (pt)
AU (2) AU7807301A (pt)
BG (1) BG107502A (pt)
BR (1) BR0113140A (pt)
CA (1) CA2417636A1 (pt)
CY (1) CY1105321T1 (pt)
DE (1) DE60120986T2 (pt)
DK (1) DK1305047T3 (pt)
EE (1) EE200300047A (pt)
ES (1) ES2261447T3 (pt)
HR (1) HRP20030121A2 (pt)
HU (1) HUP0300686A3 (pt)
IL (1) IL153933A0 (pt)
LV (1) LV13033B (pt)
MX (1) MXPA03000836A (pt)
NO (1) NO20030475L (pt)
NZ (1) NZ523688A (pt)
PL (1) PL364521A1 (pt)
PT (1) PT1305047E (pt)
SI (1) SI21123A (pt)
SK (1) SK1222003A3 (pt)
WO (1) WO2002009762A2 (pt)
YU (1) YU6703A (pt)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2004266153A1 (en) * 2003-08-22 2005-03-03 Bayer Schering Pharma Aktiengesellschaft Chemokine inhibiting piperazine derivatives and their use to treat myocarditis
US10499828B2 (en) * 2004-03-05 2019-12-10 Lifescience Solutions, Llc System and method for heart monitoring
US7917195B2 (en) 2004-03-05 2011-03-29 Lifesciences Solutions LLC Systems, methods and computer program products for heart monitoring
US8103065B2 (en) * 2006-01-05 2012-01-24 Lifescience Solutions Llc Assessment of medical conditions
US20110009758A1 (en) * 2009-07-10 2011-01-13 Lifescience Solutions Llc System and method for heart monitoring

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6323206B1 (en) 1996-07-12 2001-11-27 Millennium Pharmaceuticals, Inc. Chemokine receptor antagonists and methods of use therefor
CN1248968A (zh) 1997-02-26 2000-03-29 辉瑞大药厂 杂芳基-己酸酰胺衍生物、其制备方法及其作为MIP-1α与其CCRI受体结合的选择性抑制剂的用途
US6207665B1 (en) * 1997-06-12 2001-03-27 Schering Aktiengesellschaft Piperazine derivatives and their use as anti-inflammatory agents
US6433165B1 (en) 1998-01-21 2002-08-13 Millennium Pharmaceuticals, Inc. Chemokine receptor antagonists and methods of use therefor
DE69928226T8 (de) 1998-01-21 2006-10-19 Millennium Pharmaceuticals, Inc., Cambridge Chemokin rezeptor antagonisten und verwendung
AU752407B2 (en) 1998-02-05 2002-09-19 Pfizer Products Inc. Novel dihydroxyhexanoic acid derivatives
EP1000626A1 (en) 1998-09-18 2000-05-17 Applied Research Systems ARS Holding N.V. Chemokine receptor antagonist and cyclosporin in combined therapy
EP1152752A1 (en) 1999-01-29 2001-11-14 Millennium Pharmaceuticals, Inc. Methods for preventing graft rejection and ischemia-reperfusion injury

Also Published As

Publication number Publication date
BG107502A (en) 2003-07-31
AU2001278073B2 (en) 2005-06-30
YU6703A (sh) 2006-05-25
DE60120986T2 (de) 2006-11-23
CN1655818A (zh) 2005-08-17
MXPA03000836A (es) 2003-06-06
JP2004530630A (ja) 2004-10-07
ES2261447T3 (es) 2006-11-16
US6740636B2 (en) 2004-05-25
CA2417636A1 (en) 2002-02-07
ATE330634T1 (de) 2006-07-15
HUP0300686A3 (en) 2005-03-29
EP1305047A2 (en) 2003-05-02
LV13033B (en) 2004-02-20
DE60120986D1 (de) 2006-08-03
IL153933A0 (en) 2003-07-31
SK1222003A3 (en) 2003-09-11
EP1305047B1 (en) 2006-06-21
WO2002009762A2 (en) 2002-02-07
AU7807301A (en) 2002-02-13
KR20030048000A (ko) 2003-06-18
BR0113140A (pt) 2003-06-24
NO20030475L (no) 2003-03-28
US20020039997A1 (en) 2002-04-04
EE200300047A (et) 2004-10-15
HRP20030121A2 (en) 2005-02-28
HUP0300686A2 (hu) 2003-08-28
DK1305047T3 (da) 2006-10-23
PT1305047E (pt) 2006-11-30
NZ523688A (en) 2005-04-29
CY1105321T1 (el) 2010-03-03
SI21123A (sl) 2003-08-31
NO20030475D0 (no) 2003-01-30
WO2002009762A3 (en) 2003-01-09

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Legal Events

Date Code Title Description
REFS Decisions on refusal to grant patents (taken after the publication of the particulars of the applications)