PL3294770T3 - Sposoby terapeutyczne i diagnostyczne stosowane w przypadku nowotworu - Google Patents
Sposoby terapeutyczne i diagnostyczne stosowane w przypadku nowotworuInfo
- Publication number
- PL3294770T3 PL3294770T3 PL16724821.0T PL16724821T PL3294770T3 PL 3294770 T3 PL3294770 T3 PL 3294770T3 PL 16724821 T PL16724821 T PL 16724821T PL 3294770 T3 PL3294770 T3 PL 3294770T3
- Authority
- PL
- Poland
- Prior art keywords
- cancer
- therapeutic
- diagnostic methods
- diagnostic
- methods
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2827—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against B7 molecules, e.g. CD80, CD86
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
- G01N33/57423—Specifically defined cancers of lung
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
- G01N2333/70503—Immunoglobulin superfamily, e.g. VCAMs, PECAM, LFA-3
- G01N2333/70532—B7 molecules, e.g. CD80, CD86
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Pathology (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Analytical Chemistry (AREA)
- Wood Science & Technology (AREA)
- Oncology (AREA)
- Hospice & Palliative Care (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Hematology (AREA)
- Microbiology (AREA)
- Zoology (AREA)
- Urology & Nephrology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- General Physics & Mathematics (AREA)
- General Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562160561P | 2015-05-12 | 2015-05-12 | |
| US201562168700P | 2015-05-29 | 2015-05-29 | |
| PCT/US2016/032112 WO2016183326A1 (en) | 2015-05-12 | 2016-05-12 | Therapeutic and diagnostic methods for cancer |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PL3294770T3 true PL3294770T3 (pl) | 2021-03-22 |
| PL3294770T5 PL3294770T5 (pl) | 2024-12-09 |
Family
ID=56072467
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL16724821.0T PL3294770T5 (pl) | 2015-05-12 | 2016-05-12 | Sposoby terapeutyczne i diagnostyczne stosowane w przypadku nowotworu |
Country Status (21)
| Country | Link |
|---|---|
| US (2) | US20180030138A1 (pl) |
| EP (2) | EP3294770B2 (pl) |
| JP (3) | JP7048319B2 (pl) |
| KR (2) | KR20180008449A (pl) |
| CN (1) | CN107667119A (pl) |
| AU (2) | AU2016262074A1 (pl) |
| CA (1) | CA2983282A1 (pl) |
| DK (1) | DK3294770T4 (pl) |
| ES (1) | ES2835866T5 (pl) |
| FI (1) | FI3294770T4 (pl) |
| HK (1) | HK1250376A1 (pl) |
| HR (1) | HRP20201900T4 (pl) |
| HU (1) | HUE051815T2 (pl) |
| IL (2) | IL255312B (pl) |
| LT (1) | LT3294770T (pl) |
| MX (2) | MX2017014381A (pl) |
| PL (1) | PL3294770T5 (pl) |
| PT (1) | PT3294770T (pl) |
| RS (1) | RS61152B2 (pl) |
| SI (1) | SI3294770T2 (pl) |
| WO (1) | WO2016183326A1 (pl) |
Families Citing this family (43)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10301273B2 (en) | 2014-08-07 | 2019-05-28 | Mayo Foundation For Medical Education And Research | Compounds and methods for treating cancer |
| JP6826055B2 (ja) | 2015-03-13 | 2021-02-03 | サイトメックス セラピューティクス インコーポレイテッド | 抗pdl1抗体、活性化可能抗pdl1抗体、およびその使用方法 |
| RS61152B2 (sr) | 2015-05-12 | 2024-06-28 | Hoffmann La Roche | Terapeutski i dijagnostički postupci za lečenje raka |
| CN108025035B (zh) | 2015-08-03 | 2023-06-13 | Enb治疗公司 | 用于治疗与etbr激活相关的癌症的组合物和方法 |
| HUE049620T2 (hu) * | 2015-08-17 | 2020-09-28 | Kura Oncology Inc | Módszerek rákos páciensek kezelésére farneziltranszferáz inhibitorokkal |
| ES2837428T3 (es) | 2016-01-08 | 2021-06-30 | Hoffmann La Roche | Procedimientos de tratamiento de cánceres positivos para CEA usando antagonistas de unión al eje PD-1 y anticuerpos biespecíficos anti-CEA/anti-CD3 |
| WO2018097166A1 (ja) * | 2016-11-24 | 2018-05-31 | 第一三共株式会社 | Pd-1免疫チェックポイント阻害剤による治療に対するがんの感受性を予測する方法 |
| AU2018205233A1 (en) * | 2017-01-07 | 2019-07-11 | Merck Patent Gmbh | Dosing regimens and dosage forms for targeted TGFβ inhibition |
| JP7105238B2 (ja) * | 2017-01-18 | 2022-07-22 | ジェネンテック, インコーポレイテッド | 抗pd-l1抗体に対するイディオタイプ抗体及びそれらの使用 |
| US20190360051A1 (en) * | 2017-02-17 | 2019-11-28 | Stichting Vumc | Swarm intelligence-enhanced diagnosis and therapy selection for cancer using tumor- educated platelets |
| MX2019009772A (es) * | 2017-02-21 | 2019-12-02 | Regeneron Pharma | Anticuerpos anti-pd-1 para el tratamiento del cancer de pulmon. |
| US11596629B2 (en) | 2017-02-28 | 2023-03-07 | Mayo Foundation For Medical Education And Research | Compounds and methods for treating cancer |
| ES2953595T3 (es) | 2017-03-01 | 2023-11-14 | Hoffmann La Roche | Procedimientos diagnósticos y terapéuticos para el cáncer |
| BR112019025188A2 (pt) | 2017-06-01 | 2020-06-23 | Cytomx Therapeutics, Inc. | Anticorpos anti-pdl1 ativáveis e métodos de uso dos mesmos |
| IL271888B2 (en) | 2017-07-21 | 2024-09-01 | Genentech Inc | Therapeutic and diagnostic methods for cancer |
| US10269803B2 (en) * | 2017-08-31 | 2019-04-23 | Taiwan Semiconductor Manufacturing Company, Ltd. | Hybrid scheme for improved performance for P-type and N-type FinFETs |
| EA202091630A1 (ru) | 2018-01-12 | 2020-12-04 | Инб Терапьютикс, Инк. | Дейтерированные соединения, композиции и способы для лечения раков, связанных с активацией etbr |
| CN112424222A (zh) * | 2018-02-17 | 2021-02-26 | 冠科美博有限公司 | 使用中性粒细胞调节剂与免疫检查点调节剂的组合的癌症治疗 |
| US11243207B2 (en) | 2018-03-29 | 2022-02-08 | Mayo Foundation For Medical Education And Research | Assessing and treating cancer |
| WO2019207030A1 (en) * | 2018-04-26 | 2019-10-31 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods for predicting a response with an immune checkpoint inhibitor in a patient suffering from a lung cancer |
| JP2021524744A (ja) * | 2018-05-21 | 2021-09-16 | ナノストリング テクノロジーズ,インコーポレイティド | 分子遺伝子シグネチャーとその使用方法 |
| TW202011991A (zh) * | 2018-07-18 | 2020-04-01 | 美商建南德克公司 | 用pd-1軸結合拮抗劑、抗代謝劑及鉑劑治療肺癌之方法 |
| KR102084196B1 (ko) | 2018-08-29 | 2020-03-03 | 연세대학교 산학협력단 | 면역 항암 요법의 치료 반응에 관한 정보 제공 방법 및 이를 이용한 키트 |
| ES2955032T3 (es) | 2018-09-21 | 2023-11-28 | Hoffmann La Roche | Métodos de diagnóstico para el cáncer de mama triple negativo |
| AU2019361983A1 (en) | 2018-10-18 | 2021-05-20 | Genentech, Inc. | Diagnostic and therapeutic methods for sarcomatoid kidney cancer |
| CN113164599B (zh) * | 2018-12-24 | 2023-08-01 | 正大天晴药业集团股份有限公司 | 抗pd-l1单克隆抗体治疗癌症的用途 |
| WO2020227100A1 (en) * | 2019-05-03 | 2020-11-12 | Cornell University | Markers for identifying and quantifying of nucleic acid sequence mutation, expression, splice variant, translocation, copy number, or methylation changes |
| CN111973739B (zh) * | 2019-05-23 | 2024-02-13 | 正大天晴药业集团股份有限公司 | 抗pd-l1单克隆抗体治疗癌症的用途 |
| CN112805566A (zh) * | 2019-07-29 | 2021-05-14 | 上海谷森医药有限公司 | 用于吸入治疗肺癌的抗体类药物制剂 |
| EP3792632A1 (en) * | 2019-09-16 | 2021-03-17 | Vito NV | Immunotherapy markers |
| WO2021154761A1 (en) | 2020-01-27 | 2021-08-05 | Genentech, Inc. | Methods for treatment of cancer with an anti-tigit antagonist antibody |
| WO2021202959A1 (en) * | 2020-04-03 | 2021-10-07 | Genentech, Inc. | Therapeutic and diagnostic methods for cancer |
| EP4147052A1 (en) * | 2020-05-05 | 2023-03-15 | F. Hoffmann-La Roche AG | Predicting response to pd-1 axis inhibitors |
| CA3181820A1 (en) | 2020-06-16 | 2021-12-23 | Genentech, Inc. | Methods and compositions for treating triple-negative breast cancer |
| WO2022232503A1 (en) | 2021-04-30 | 2022-11-03 | Genentech, Inc. | Therapeutic and diagnostic methods and compositions for cancer |
| EP4384276A4 (en) * | 2021-08-10 | 2025-06-25 | Apexigen, Inc. | Biomarkers for cd40 agonist therapy |
| AU2023269154A1 (en) | 2022-05-12 | 2024-10-10 | Genentech, Inc. | Methods and compositions comprising a shp2 inhibitor and a pd-l1 binding antagonist |
| KR20250022049A (ko) | 2022-06-07 | 2025-02-14 | 제넨테크, 인크. | 항-pd-l1 길항제 및 항-tigit 길항제 항체를 포함하는, 폐암 치료의 효율을 결정하는 방법 |
| WO2024163494A1 (en) | 2023-01-31 | 2024-08-08 | F. Hoffmann-La Roche Ag | Methods and compositions for treating non-small cell lung cancer and triple-negative breast cancer |
| WO2024163009A1 (en) | 2023-01-31 | 2024-08-08 | Genentech, Inc. | Methods and compositions for treating urothelial bladder cancer |
| IL323044A (en) | 2023-03-06 | 2025-10-01 | Genentech Inc | Prognostic and therapeutic methods for non-small cell lung cancer |
| WO2025049277A1 (en) | 2023-08-25 | 2025-03-06 | Genentech, Inc. | Methods and compositions for treating non-small cell lung cancer comprising an anti-tigit antagonist antibody and a pd-1 axis binding antagonist |
| WO2025174933A1 (en) | 2024-02-14 | 2025-08-21 | Genentech, Inc. | Methods for treatment of pancreatic cancer with anti-pd-l1 ab, anti-tigit ab, gemcitabine and nab-placlitaxel |
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