PL3186283T3 - Terapia skojarzona z zastosowaniem skierowanej przeciw nowotworowi, opartej na wariancie IL2 immunocytokiny oraz przeciwciał przeciwko ludzkiemu ligandowi programowanej śmierci PD-L1 - Google Patents

Terapia skojarzona z zastosowaniem skierowanej przeciw nowotworowi, opartej na wariancie IL2 immunocytokiny oraz przeciwciał przeciwko ludzkiemu ligandowi programowanej śmierci PD-L1

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Publication number
PL3186283T3
PL3186283T3 PL15753700T PL15753700T PL3186283T3 PL 3186283 T3 PL3186283 T3 PL 3186283T3 PL 15753700 T PL15753700 T PL 15753700T PL 15753700 T PL15753700 T PL 15753700T PL 3186283 T3 PL3186283 T3 PL 3186283T3
Authority
PL
Poland
Prior art keywords
tumor
targeted
combination therapy
antibodies against
against human
Prior art date
Application number
PL15753700T
Other languages
English (en)
Inventor
Pablo Umana
Christian Klein
Valeria G. Nicolini
Original Assignee
F. Hoffmann-La Roche Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F. Hoffmann-La Roche Ag filed Critical F. Hoffmann-La Roche Ag
Publication of PL3186283T3 publication Critical patent/PL3186283T3/pl

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    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
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    • C07K16/2803Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2827Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against B7 molecules, e.g. CD80, CD86
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    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
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PL15753700T 2014-08-29 2015-08-25 Terapia skojarzona z zastosowaniem skierowanej przeciw nowotworowi, opartej na wariancie IL2 immunocytokiny oraz przeciwciał przeciwko ludzkiemu ligandowi programowanej śmierci PD-L1 PL3186283T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP14182778 2014-08-29
EP15753700.2A EP3186283B1 (en) 2014-08-29 2015-08-25 Combination therapy of tumor-targeted il-2 variant immunocytokines and antibodies against human pd-l1
PCT/EP2015/069399 WO2016030350A1 (en) 2014-08-29 2015-08-25 Combination therapy of tumor-targeted il-2 variant immunocytokines and antibodies against human pd-l1

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PL3186283T3 true PL3186283T3 (pl) 2020-05-18

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PL15753700T PL3186283T3 (pl) 2014-08-29 2015-08-25 Terapia skojarzona z zastosowaniem skierowanej przeciw nowotworowi, opartej na wariancie IL2 immunocytokiny oraz przeciwciał przeciwko ludzkiemu ligandowi programowanej śmierci PD-L1

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US (3) US20160175397A1 (pl)
EP (1) EP3186283B1 (pl)
JP (3) JP6603707B2 (pl)
KR (1) KR102058846B1 (pl)
CN (1) CN106794245B (pl)
AR (1) AR101697A1 (pl)
AU (1) AU2015308527C1 (pl)
BR (1) BR112016030670A2 (pl)
CA (1) CA2951604A1 (pl)
DK (1) DK3186283T3 (pl)
ES (1) ES2774380T3 (pl)
HR (1) HRP20200272T1 (pl)
HU (1) HUE047806T2 (pl)
IL (1) IL249162B (pl)
LT (1) LT3186283T (pl)
MX (1) MX2017002426A (pl)
MY (1) MY193723A (pl)
PL (1) PL3186283T3 (pl)
PT (1) PT3186283T (pl)
RS (1) RS59939B1 (pl)
RU (1) RU2710354C2 (pl)
SG (1) SG11201701157UA (pl)
SI (1) SI3186283T1 (pl)
WO (1) WO2016030350A1 (pl)

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