MX2017002426A - Terapia de combinacion de inmunocitocinas variantes de il-2 dirigidas a tumores y anticuerpos contra pd-l1 humana. - Google Patents
Terapia de combinacion de inmunocitocinas variantes de il-2 dirigidas a tumores y anticuerpos contra pd-l1 humana.Info
- Publication number
- MX2017002426A MX2017002426A MX2017002426A MX2017002426A MX2017002426A MX 2017002426 A MX2017002426 A MX 2017002426A MX 2017002426 A MX2017002426 A MX 2017002426A MX 2017002426 A MX2017002426 A MX 2017002426A MX 2017002426 A MX2017002426 A MX 2017002426A
- Authority
- MX
- Mexico
- Prior art keywords
- targeted
- tumor
- combination therapy
- antibodies against
- against human
- Prior art date
Links
- 206010028980 Neoplasm Diseases 0.000 title abstract 2
- 238000002648 combination therapy Methods 0.000 title abstract 2
- 229940127130 immunocytokine Drugs 0.000 title abstract 2
- 101001117317 Homo sapiens Programmed cell death 1 ligand 1 Proteins 0.000 abstract 1
- 108010002350 Interleukin-2 Proteins 0.000 abstract 1
- 102000048776 human CD274 Human genes 0.000 abstract 1
Classifications
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- A61K38/19—Cytokines; Lymphokines; Interferons
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Abstract
La presente invencion se refiere a la terapia de combinacion de inmunocitocinas variantes de IL-2 dirigidas a tumores con anticuerpos especificos que se unen a PD-L1 humano.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP14182778 | 2014-08-29 | ||
PCT/EP2015/069399 WO2016030350A1 (en) | 2014-08-29 | 2015-08-25 | Combination therapy of tumor-targeted il-2 variant immunocytokines and antibodies against human pd-l1 |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2017002426A true MX2017002426A (es) | 2017-06-20 |
Family
ID=51535312
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2017002426A MX2017002426A (es) | 2014-08-29 | 2015-08-25 | Terapia de combinacion de inmunocitocinas variantes de il-2 dirigidas a tumores y anticuerpos contra pd-l1 humana. |
Country Status (24)
Country | Link |
---|---|
US (3) | US20160175397A1 (es) |
EP (1) | EP3186283B1 (es) |
JP (3) | JP6603707B2 (es) |
KR (1) | KR102058846B1 (es) |
CN (1) | CN106794245B (es) |
AR (1) | AR101697A1 (es) |
AU (1) | AU2015308527C1 (es) |
BR (1) | BR112016030670A2 (es) |
CA (1) | CA2951604A1 (es) |
DK (1) | DK3186283T3 (es) |
ES (1) | ES2774380T3 (es) |
HR (1) | HRP20200272T1 (es) |
HU (1) | HUE047806T2 (es) |
IL (1) | IL249162B (es) |
LT (1) | LT3186283T (es) |
MX (1) | MX2017002426A (es) |
MY (1) | MY193723A (es) |
PL (1) | PL3186283T3 (es) |
PT (1) | PT3186283T (es) |
RS (1) | RS59939B1 (es) |
RU (1) | RU2710354C2 (es) |
SG (1) | SG11201701157UA (es) |
SI (1) | SI3186283T1 (es) |
WO (1) | WO2016030350A1 (es) |
Families Citing this family (99)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PE20120341A1 (es) | 2008-12-09 | 2012-04-24 | Genentech Inc | Anticuerpos anti-pd-l1 y su uso para mejorar la funcion de celulas t |
DK3489255T3 (da) | 2011-02-10 | 2021-08-23 | Roche Glycart Ag | Muterede interleukin-2-polypeptider |
WO2012117002A1 (en) * | 2011-03-02 | 2012-09-07 | Roche Glycart Ag | Cea antibodies |
EA201892619A1 (ru) | 2011-04-29 | 2019-04-30 | Роше Гликарт Аг | Иммуноконъюгаты, содержащие мутантные полипептиды интерлейкина-2 |
RU2605390C2 (ru) | 2011-08-23 | 2016-12-20 | Рош Гликарт Аг | Биспецифические антитела, специфичные к антигенам, активирующим т-клетки, и опухолевому антигену, и способы их применения |
KR20150064068A (ko) | 2012-10-08 | 2015-06-10 | 로슈 글리카트 아게 | 2개의 Fab 단편을 포함하는 FC-부재 항체 및 이용 방법 |
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