PL3081566T3 - Pochodna 5-hydroksy-4-(trifluorometylo)pirazolopirydyny - Google Patents
Pochodna 5-hydroksy-4-(trifluorometylo)pirazolopirydynyInfo
- Publication number
- PL3081566T3 PL3081566T3 PL14869320T PL14869320T PL3081566T3 PL 3081566 T3 PL3081566 T3 PL 3081566T3 PL 14869320 T PL14869320 T PL 14869320T PL 14869320 T PL14869320 T PL 14869320T PL 3081566 T3 PL3081566 T3 PL 3081566T3
- Authority
- PL
- Poland
- Prior art keywords
- trifluoromethyl
- hydroxy
- pyrazolopyridine derivative
- pyrazolopyridine
- derivative
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4965—Non-condensed pyrazines
- A61K31/497—Non-condensed pyrazines containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/50—Pyridazines; Hydrogenated pyridazines
- A61K31/501—Pyridazines; Hydrogenated pyridazines not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2013258008 | 2013-12-13 | ||
| EP14869320.3A EP3081566B1 (en) | 2013-12-13 | 2014-12-12 | 5-hydroxy-4-(trifluoromethyl)pyrazolopyridine derivative |
| PCT/JP2014/082943 WO2015087994A1 (ja) | 2013-12-13 | 2014-12-12 | ５－ヒドロキシ－４－（トリフルオロメチル）ピラゾロピリジン誘導体 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL3081566T3 true PL3081566T3 (pl) | 2018-07-31 |
Family
ID=53371291
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL14869320T PL3081566T3 (pl) | 2013-12-13 | 2014-12-12 | Pochodna 5-hydroksy-4-(trifluorometylo)pirazolopirydyny |
Country Status (29)
| Country | Link |
|---|---|
| US (1) | US9796709B2 (pl) |
| EP (1) | EP3081566B1 (pl) |
| JP (1) | JP6465813B2 (pl) |
| KR (1) | KR20160096612A (pl) |
| CN (1) | CN105873928B (pl) |
| AU (1) | AU2014362144B2 (pl) |
| BR (1) | BR112016013500B8 (pl) |
| CA (1) | CA2932707C (pl) |
| CY (1) | CY1120256T1 (pl) |
| DK (1) | DK3081566T3 (pl) |
| ES (1) | ES2671377T3 (pl) |
| HR (1) | HRP20180473T1 (pl) |
| HU (1) | HUE038636T2 (pl) |
| IL (1) | IL246006B (pl) |
| LT (1) | LT3081566T (pl) |
| MX (1) | MX368576B (pl) |
| MY (1) | MY180338A (pl) |
| NO (1) | NO3081566T3 (pl) |
| PH (1) | PH12016501129B1 (pl) |
| PL (1) | PL3081566T3 (pl) |
| PT (1) | PT3081566T (pl) |
| RS (1) | RS57088B1 (pl) |
| RU (1) | RU2673810C1 (pl) |
| SG (1) | SG11201604251UA (pl) |
| SI (1) | SI3081566T1 (pl) |
| TR (1) | TR201807696T4 (pl) |
| TW (1) | TWI634120B (pl) |
| WO (1) | WO2015087994A1 (pl) |
| ZA (1) | ZA201603594B (pl) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI713534B (zh) * | 2015-06-11 | 2020-12-21 | 日商第一三共股份有限公司 | 5-羥基-4-(三氟甲基)吡唑并吡啶衍生物之結晶及其用途 |
| CN106916143B (zh) * | 2017-03-14 | 2019-09-27 | 哈尔滨医科大学 | 一种预防和治疗冠心病的药物及其应用 |
| EP3777859A4 (en) * | 2018-03-30 | 2021-11-24 | Daiichi Sankyo Company, Limited | THERAPEUTIC FOR LCAT DEFECTS |
| CN108530433A (zh) * | 2018-05-31 | 2018-09-14 | 马文军 | 一种酯类衍生物及其在防治心脑血管疾病中的应用 |
| CN108558847A (zh) * | 2018-05-31 | 2018-09-21 | 马文军 | 一种酯类衍生物及其在防治心脑血管疾病中的应用 |
| CN108658830A (zh) * | 2018-05-31 | 2018-10-16 | 马文军 | 一种酯类衍生物及其在防治心脑血管疾病中的应用 |
| CN108774242B (zh) * | 2018-08-22 | 2020-10-27 | 牡丹江医学院 | 一种防治冠心病的药物及其制备方法 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3130342B2 (ja) * | 1991-10-04 | 2001-01-31 | 日産化学工業株式会社 | 動脈硬化性血管内膜肥厚抑制薬 |
| BR0313262A (pt) | 2002-08-07 | 2005-07-12 | Mitsubishi Pharma Corp | Compostos de dihidropirazolpiridina |
| US7135575B2 (en) * | 2003-03-03 | 2006-11-14 | Array Biopharma, Inc. | P38 inhibitors and methods of use thereof |
| EP1670761B1 (en) | 2003-10-01 | 2009-01-28 | Xention Limited | Tetrahydro-naphthalene and urea derivatives |
| ES2376396T3 (es) | 2006-06-26 | 2012-03-13 | Amgen Inc. | Método para tratar aterosclerosis. |
| CA2689575A1 (en) * | 2007-06-20 | 2008-12-24 | Merck Sharp & Dohme Corp. | Cetp inhibitors derived from benzoxazole arylamides |
| WO2009081789A1 (ja) | 2007-12-26 | 2009-07-02 | Banyu Pharmaceutical Co., Ltd. | スルホニル置換六員環誘導体 |
| US20120041009A1 (en) | 2009-05-18 | 2012-02-16 | Sumitomo Chemical Company, Limited | Pyrimidine compound and its use in pest control |
| KR101764458B1 (ko) * | 2010-07-09 | 2017-08-02 | 다이이찌 산쿄 가부시키가이샤 | 치환 피리딘 화합물 |
| ES2530345T3 (es) | 2010-09-02 | 2015-03-02 | Merck Patent Gmbh | Derivados de pirazolopiridinona como antagonistas del receptor del LPA |
| CN103958511A (zh) * | 2011-09-27 | 2014-07-30 | 雷迪博士实验室有限公司 | 作为胆固醇酯转移蛋白(CETP)抑制剂用于治疗动脉粥样硬化的5-苄基氨基甲基-6-氨基吡唑并[3,4-b]吡啶衍生物 |
| JP6097225B2 (ja) * | 2012-01-06 | 2017-03-15 | 第一三共株式会社 | 置換ピリジン化合物の酸付加塩 |
| WO2013137371A1 (ja) * | 2012-03-15 | 2013-09-19 | 興和株式会社 | 新規ピリミジン化合物及びそれらを含有する医薬 |
| CN104781257A (zh) * | 2012-06-14 | 2015-07-15 | 第一三共株式会社 | 哌啶基吡唑并吡啶衍生物 |
-
2014
- 2014-12-12 JP JP2015552528A patent/JP6465813B2/ja active Active
- 2014-12-12 HU HUE14869320A patent/HUE038636T2/hu unknown
- 2014-12-12 BR BR112016013500A patent/BR112016013500B8/pt not_active IP Right Cessation
- 2014-12-12 AU AU2014362144A patent/AU2014362144B2/en not_active Ceased
- 2014-12-12 TR TR2018/07696T patent/TR201807696T4/tr unknown
- 2014-12-12 KR KR1020167015459A patent/KR20160096612A/ko not_active Application Discontinuation
- 2014-12-12 EP EP14869320.3A patent/EP3081566B1/en active Active
- 2014-12-12 ES ES14869320.3T patent/ES2671377T3/es active Active
- 2014-12-12 SG SG11201604251UA patent/SG11201604251UA/en unknown
- 2014-12-12 MX MX2016007257A patent/MX368576B/es active IP Right Grant
- 2014-12-12 DK DK14869320.3T patent/DK3081566T3/en active
- 2014-12-12 MY MYPI2016000996A patent/MY180338A/en unknown
- 2014-12-12 SI SI201430677T patent/SI3081566T1/en unknown
- 2014-12-12 PT PT148693203T patent/PT3081566T/pt unknown
- 2014-12-12 WO PCT/JP2014/082943 patent/WO2015087994A1/ja active Application Filing
- 2014-12-12 US US15/100,654 patent/US9796709B2/en active Active
- 2014-12-12 NO NO14869320A patent/NO3081566T3/no unknown
- 2014-12-12 RS RS20180370A patent/RS57088B1/sr unknown
- 2014-12-12 CN CN201480067845.0A patent/CN105873928B/zh not_active Expired - Fee Related
- 2014-12-12 RU RU2016128050A patent/RU2673810C1/ru not_active IP Right Cessation
- 2014-12-12 CA CA2932707A patent/CA2932707C/en not_active Expired - Fee Related
- 2014-12-12 TW TW103143409A patent/TWI634120B/zh not_active IP Right Cessation
- 2014-12-12 LT LTEP14869320.3T patent/LT3081566T/lt unknown
- 2014-12-12 PL PL14869320T patent/PL3081566T3/pl unknown
-
2016
- 2016-05-25 ZA ZA2016/03594A patent/ZA201603594B/en unknown
- 2016-06-02 IL IL246006A patent/IL246006B/en not_active IP Right Cessation
- 2016-06-10 PH PH12016501129A patent/PH12016501129B1/en unknown
-
2018
- 2018-03-21 HR HRP20180473TT patent/HRP20180473T1/hr unknown
- 2018-05-23 CY CY20181100545T patent/CY1120256T1/el unknown
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