PL2764367T3 - Sposoby diagnozowania choroby Alzheimera - Google Patents

Sposoby diagnozowania choroby Alzheimera

Info

Publication number
PL2764367T3
PL2764367T3 PL12761989T PL12761989T PL2764367T3 PL 2764367 T3 PL2764367 T3 PL 2764367T3 PL 12761989 T PL12761989 T PL 12761989T PL 12761989 T PL12761989 T PL 12761989T PL 2764367 T3 PL2764367 T3 PL 2764367T3
Authority
PL
Poland
Prior art keywords
disease
diagnosing alzheimer
alzheimer
diagnosing
Prior art date
Application number
PL12761989T
Other languages
English (en)
Inventor
Günther STAFFLER
Andreas Mairhofer
Achim Schneeberger
Martina LUTTEROVA
Walter Schmidt
Frank Mattner
Original Assignee
Affiris Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Affiris Ag filed Critical Affiris Ag
Publication of PL2764367T3 publication Critical patent/PL2764367T3/pl

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/566Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/564Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G01N33/6896Neurological disorders, e.g. Alzheimer's disease
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/46Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
    • G01N2333/47Assays involving proteins of known structure or function as defined in the subgroups
    • G01N2333/4701Details
    • G01N2333/4709Amyloid plaque core protein
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/28Neurological disorders
    • G01N2800/2814Dementia; Cognitive disorders
    • G01N2800/2821Alzheimer

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Rehabilitation Therapy (AREA)
  • Rheumatology (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Sampling And Sample Adjustment (AREA)
PL12761989T 2011-10-04 2012-09-20 Sposoby diagnozowania choroby Alzheimera PL2764367T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP11183842.1A EP2579042B1 (en) 2011-10-04 2011-10-04 Method for detecting Aß-specific antibodies in a biological sample
EP12761989.8A EP2764367B1 (en) 2011-10-04 2012-09-20 Method for diagnosing alzheimer's disease (ad)
PCT/EP2012/068493 WO2013050248A1 (en) 2011-10-04 2012-09-20 Method for diagnosing alzheimer's disease (ad)

Publications (1)

Publication Number Publication Date
PL2764367T3 true PL2764367T3 (pl) 2019-04-30

Family

ID=46888451

Family Applications (2)

Application Number Title Priority Date Filing Date
PL11183842T PL2579042T3 (pl) 2011-10-04 2011-10-04 Sposób wykrywania przeciwciał swoistych wobec Aß w próbce biologicznej
PL12761989T PL2764367T3 (pl) 2011-10-04 2012-09-20 Sposoby diagnozowania choroby Alzheimera

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PL11183842T PL2579042T3 (pl) 2011-10-04 2011-10-04 Sposób wykrywania przeciwciał swoistych wobec Aß w próbce biologicznej

Country Status (23)

Country Link
US (2) US9625459B2 (pl)
EP (3) EP2579042B1 (pl)
JP (2) JP6162127B2 (pl)
KR (2) KR20140073568A (pl)
CN (2) CN103842824A (pl)
AR (1) AR088108A1 (pl)
AU (2) AU2012320767A1 (pl)
BR (2) BR112014008088A2 (pl)
CA (2) CA2850843A1 (pl)
CY (1) CY1115624T1 (pl)
DK (2) DK2579042T3 (pl)
ES (2) ES2496341T3 (pl)
HR (1) HRP20140937T1 (pl)
IL (2) IL231057A0 (pl)
MX (2) MX2014003983A (pl)
PL (2) PL2579042T3 (pl)
PT (1) PT2579042E (pl)
RS (1) RS53496B1 (pl)
RU (2) RU2014117671A (pl)
SG (2) SG11201400229XA (pl)
SI (1) SI2579042T1 (pl)
SM (1) SMT201400145B (pl)
WO (2) WO2013050249A1 (pl)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2787349A1 (en) 2013-04-03 2014-10-08 Affiris AG Method for detecting proteinopathy-specific antibodies in a biological sample
EP2787347A1 (en) * 2013-04-03 2014-10-08 Affiris AG Method for detecting Aß-specific antibodies in a biological sample
WO2015165961A1 (en) 2014-04-29 2015-11-05 Affiris Ag Treatment and prevention of alzheimer's disease (ad)
KR101658620B1 (ko) * 2014-12-02 2016-09-23 주식회사 피플바이오 응집형-형성 폴리펩타이드의 응집형을 검출하는 방법
KR20170108203A (ko) * 2016-03-16 2017-09-27 주식회사 피플바이오 응집형-형성 폴리펩타이드의 응집형을 검출하는 방법
KR101871895B1 (ko) * 2016-04-20 2018-06-28 한국과학기술연구원 응집 단백질의 고감도 광 산화 증폭 면역 분석을 통한 체액기반의 퇴행성 신경질환 진단 방법
EP3242134A1 (en) * 2016-05-04 2017-11-08 Euroimmun Medizinische Labordiagnostika AG Assay for the diagnosis of a neurological disease
KR101989383B1 (ko) * 2017-04-04 2019-06-14 조선대학교산학협력단 알츠하이머성 치매의 조기진단을 위한 펩타이드 프로브
KR102108171B1 (ko) * 2018-08-27 2020-05-08 광주과학기술원 알츠하이머성 치매 진단용 펩타이드 바이오마커
WO2020045962A1 (ko) * 2018-08-27 2020-03-05 광주과학기술원 알츠하이머성 치매 진단용 펩타이드 바이오마커
CN113063949B (zh) * 2021-03-23 2024-11-15 中国医学科学院输血研究所 一种血浆中特异性IgM抗体的定量测定方法
CN113075398A (zh) * 2021-03-23 2021-07-06 中国医学科学院输血研究所 一种血浆中特异性IgG抗体的定量测定方法

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US5262332A (en) * 1989-04-05 1993-11-16 Brigham And Women's Hospital Diagnostic method for Alzheimer's disease: examination of non-neural tissue
CA2203142C (en) * 1994-10-19 2006-01-31 Rudolph E. Tanzi A diagnostic assay for alzheimer's disease: assessment of a.beta. abnormalities
US7427392B1 (en) 1994-11-14 2008-09-23 Elan Pharmaceuticals, Inc. Methods for aiding in the diagnosis of alzheimer's disease by measuring amyloid-β peptide (x-≧41) and tau
TWI239847B (en) 1997-12-02 2005-09-21 Elan Pharm Inc N-terminal fragment of Abeta peptide and an adjuvant for preventing and treating amyloidogenic disease
UA81216C2 (en) * 1999-06-01 2007-12-25 Prevention and treatment of amyloid disease
ATE354655T1 (de) 1999-08-24 2007-03-15 Medarex Inc Humane antikörper gegen ctla-4 und deren verwendungen
AT413945B (de) 2003-01-14 2006-07-15 Mattner Frank Dr Impfstoff für die alzheimer-krankheit
WO2004074837A1 (en) * 2003-02-24 2004-09-02 Digitalbiotech Co., Ltd. Method for measuring the level of anti-beta-amyloid antibody in body fluids and diagnostic kit for alzheimer’s disease using same
AT413336B (de) 2003-09-12 2006-02-15 Mattner Frank Dr Apherese-vorrichtung
AT413946B (de) 2004-07-13 2006-07-15 Mattner Frank Dr Impfstoff gegen die alzheimer-krankheit
AT500483B1 (de) 2004-07-13 2006-01-15 Mattner Frank Dr Set zur vorbeugung oder behandlung der alzheimer'schen erkrankung
DE102005006217B4 (de) * 2005-02-07 2007-08-16 Universitätsklinikum Hamburg-Eppendorf Diagnose von allergischen Erkrankungen und/oder atopischen Erkrankungen durch Nachweis von Autoantikörpern gegen CD28 in humanem Serum
JP4937143B2 (ja) * 2005-03-05 2012-05-23 アボット ゲーエムベーハー ウント カンパニー カーゲー 非拡散性球状Aβ(X−38..43)オリゴマー構造エピトープに対して特異性を有する自己抗体を検出する方法
TW200726774A (en) * 2005-06-30 2007-07-16 Merck & Co Inc Composition and method for producing stable amyloid beta oligomers
MX336435B (es) * 2005-07-08 2016-01-19 Dsm Ip Assets Bv Acidos grasos poliinsaturados para el tratamiento de demencia y condiciones relacionadas con pre-demencia.
SG10201404801YA (en) * 2005-12-12 2014-09-26 Ac Immune Sa Monoclonal antibody
PL2104682T3 (pl) * 2007-01-11 2017-03-31 Michael Bacher Diagnostyka i leczenie choroby Alzheimera i innych chorób neurodegeneracyjnych
US7771957B2 (en) * 2007-10-19 2010-08-10 The Regents Of The University Of California Method for diagnosing alzheimer's disease
WO2009051599A1 (en) * 2007-10-19 2009-04-23 The Regents Of The University Of California Use of biomarkers of alzheimer's disease for diagnostic tests and drug screening
AT506535B1 (de) 2008-02-22 2010-04-15 Affiris Forschungs & Entwicklungs Gmbh Vaccine enthaltend alpha-synuclein-mimotope auf basis von peptiden
AT506820B1 (de) 2008-06-12 2011-07-15 Affiris Forschungs Und Entwicklungs Gmbh Vakzine gegen alzheimer-krankheit
BRPI0915134A2 (pt) 2008-06-12 2016-02-16 Affiris Ag composto, e, uso de um composto
AT506819B1 (de) 2008-06-12 2011-06-15 Affiris Forschungs Und Entwicklungs Gmbh Vakzin zur behandlung von alzheimer-krankheit
WO2010099199A1 (en) * 2009-02-24 2010-09-02 Gibbons Winton G Detection of complexes of tau and amyloid
WO2010128139A1 (en) 2009-05-08 2010-11-11 Georg-August-Universität Göttingen Stiftung Öffentlichen Rechts, Universitätsmedizin Biomarkers and methods for diagnosing alzheimer's disease and/ or mild cognitive impairment
AT508638B1 (de) 2009-08-21 2011-08-15 Affiris Ag Verwendung von peptiden und polypeptiden zur behandlung und/oder prävention von synukleinopathien
US20130084245A1 (en) * 2010-02-25 2013-04-04 Wyeth Llc Pet monitoring of a-beta-directed immunotherapy

Also Published As

Publication number Publication date
ES2496341T3 (es) 2014-09-18
AU2012320766B2 (en) 2017-09-21
HRP20140937T1 (hr) 2014-12-05
US20140234877A1 (en) 2014-08-21
JP6162127B2 (ja) 2017-07-12
AU2012320767A1 (en) 2014-03-13
CA2850843A1 (en) 2013-04-11
EP2764367B1 (en) 2018-07-25
CN103842825B (zh) 2016-04-20
JP2014529088A (ja) 2014-10-30
KR20140073568A (ko) 2014-06-16
AU2012320766A1 (en) 2014-03-13
EP2579042B1 (en) 2014-07-09
DK2764367T3 (en) 2018-10-29
RU2014117671A (ru) 2015-11-10
MX2014003984A (es) 2014-05-07
CN103842825A (zh) 2014-06-04
HK1178601A1 (en) 2013-09-13
RU2014117677A (ru) 2015-11-10
IL231620A0 (en) 2014-05-28
SI2579042T1 (sl) 2014-09-30
SMT201400145B (it) 2014-11-10
DK2579042T3 (da) 2014-07-21
SG11201400223SA (en) 2014-05-29
IL231057A0 (en) 2014-03-31
EP2579042A1 (en) 2013-04-10
CA2850840A1 (en) 2013-04-11
ES2692185T3 (es) 2018-11-30
AR088108A1 (es) 2014-05-07
JP2014529087A (ja) 2014-10-30
MX2014003983A (es) 2014-05-07
PT2579042E (pt) 2014-09-09
US9625459B2 (en) 2017-04-18
EP2764367A1 (en) 2014-08-13
CY1115624T1 (el) 2017-01-04
EP2764368A1 (en) 2014-08-13
WO2013050249A1 (en) 2013-04-11
BR112014008089A2 (pt) 2017-04-18
KR20140069346A (ko) 2014-06-09
RS53496B1 (sr) 2015-02-27
US20140242727A1 (en) 2014-08-28
CN103842824A (zh) 2014-06-04
PL2579042T3 (pl) 2014-12-31
SG11201400229XA (en) 2014-05-29
BR112014008088A2 (pt) 2017-04-18
WO2013050248A1 (en) 2013-04-11

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